PL2626420T3 - Polinukleotydy kodujące epitopy hTERT ograniczone do MHC klasy I HLA-B7, ich analogi lub poliepitopy - Google Patents

Polinukleotydy kodujące epitopy hTERT ograniczone do MHC klasy I HLA-B7, ich analogi lub poliepitopy

Info

Publication number
PL2626420T3
PL2626420T3 PL13165854T PL13165854T PL2626420T3 PL 2626420 T3 PL2626420 T3 PL 2626420T3 PL 13165854 T PL13165854 T PL 13165854T PL 13165854 T PL13165854 T PL 13165854T PL 2626420 T3 PL2626420 T3 PL 2626420T3
Authority
PL
Poland
Prior art keywords
polyepitopes
hla
analogues
mhc class
polynucleotides encoding
Prior art date
Application number
PL13165854T
Other languages
English (en)
Inventor
Pierre Langlade-Demoyen
Pons Fransisco Garcia
Olivier Adotevi
Sylvain Cardinaud
Christine Neuveut
Original Assignee
Institut Pasteur
Institut National De La Sante Et De La Recherche Medicale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur, Institut National De La Sante Et De La Recherche Medicale filed Critical Institut Pasteur
Publication of PL2626420T3 publication Critical patent/PL2626420T3/pl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1276RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL13165854T 2005-07-29 2006-07-31 Polinukleotydy kodujące epitopy hTERT ograniczone do MHC klasy I HLA-B7, ich analogi lub poliepitopy PL2626420T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05291627A EP1748067A1 (en) 2005-07-29 2005-07-29 Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes

Publications (1)

Publication Number Publication Date
PL2626420T3 true PL2626420T3 (pl) 2017-01-31

Family

ID=35735256

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13165854T PL2626420T3 (pl) 2005-07-29 2006-07-31 Polinukleotydy kodujące epitopy hTERT ograniczone do MHC klasy I HLA-B7, ich analogi lub poliepitopy

Country Status (9)

Country Link
US (3) US8858931B2 (pl)
EP (3) EP1748067A1 (pl)
JP (4) JP5631545B2 (pl)
CA (1) CA2616674C (pl)
DK (2) DK1910529T3 (pl)
ES (2) ES2590462T3 (pl)
PL (1) PL2626420T3 (pl)
PT (1) PT2626420T (pl)
WO (1) WO2007014740A2 (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10767167B2 (en) 2005-07-29 2020-09-08 Institut Pasteur Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes
EP1748067A1 (en) * 2005-07-29 2007-01-31 Institut Pasteur Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes
WO2008010010A1 (en) * 2006-07-12 2008-01-24 Vaxon Biotech Identification, optimization and use of cryptic hla-b7 epitopes for immunotherapy
US20080171062A1 (en) * 2006-08-16 2008-07-17 Monica Sala-Schaeffer Recombinant HBsAg virus-like particles containing polyepitopes of interest, their production and use
WO2008106551A2 (en) * 2007-02-28 2008-09-04 The Govt. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Serv. Brachyury polypeptides and methods for use
BRPI0813626A2 (pt) * 2007-07-27 2014-12-23 Immatics Biotechnologies Gmbh Epitopos imunogênicos para a imunoterapia
US7904566B2 (en) * 2008-03-14 2011-03-08 Silicon Image, Inc. Method, apparatus, and system for employing an enhanced port multiplier
US7979589B2 (en) * 2008-03-14 2011-07-12 Silicon Image, Inc. Method, apparatus, and system for port multiplier enhancement
EP3581649A1 (en) 2010-02-16 2019-12-18 Ultimovacs ASA Polypeptides
RU2014140792A (ru) 2012-03-15 2016-05-10 Макрокьюэ, Лтд. Активированная иммуностимулирующая клеточная композиция и ее использование
CA2864838A1 (en) 2012-03-15 2013-09-19 Macrocure, Ltd. Activated immunostimulatory cell composition for therapy of infection
EP2639299A1 (en) 2012-03-16 2013-09-18 Invectys Universal cancer peptides derived from telomerase
KR102201429B1 (ko) * 2012-09-19 2021-01-12 주식회사 젬백스앤카엘 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물
WO2014105870A1 (en) * 2012-12-27 2014-07-03 Sierra Sciences, Inc. Enhancing health in mammals using telomerase reverse transcriptase gene therapy
WO2014154905A1 (en) * 2013-03-28 2014-10-02 Invectys A cancer vaccine for dogs
WO2014154904A1 (en) 2013-03-28 2014-10-02 Invectys A cancer vaccine for cats
GB201315946D0 (en) * 2013-09-06 2013-10-23 Immune Targeting Systems Its Ltd Oncology vaccine
US10183065B2 (en) * 2013-10-28 2019-01-22 Invectys Telomerase encoding DNA vaccine
DK3063280T3 (da) 2013-10-28 2019-11-11 Invectys Genelektrooverførsel ind i hudceller
CA2973978A1 (en) 2015-01-14 2016-07-21 The Brigham And Women's Hospital, Inc. Treatment of cancer with anti-lap monoclonal antibodies
US11254914B2 (en) 2015-03-12 2022-02-22 Health Research, Inc. Enrichment of CD16+ monocytes to improve dendritic cell vaccine quality
WO2016168601A1 (en) 2015-04-17 2016-10-20 Khalid Shah Agents, systems and methods for treating cancer
EP3359183B1 (en) * 2015-10-06 2020-06-17 Invectys Polyepitope constructs for use in immunotherapy
GB201519557D0 (en) 2015-11-05 2015-12-23 Univ Witwatersrand Jhb Compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions
ES2811523T3 (es) 2016-01-19 2021-03-12 Pfizer Vacunas contra el cáncer
WO2018064588A2 (en) 2016-09-30 2018-04-05 Weiner, David Tert immunogenic compositions and methods of treatment using the same
WO2018206512A1 (en) 2017-05-09 2018-11-15 Invectys Recombinant measles vaccine expressing htert
TWI837109B (zh) * 2017-12-28 2024-04-01 美商磨石生物公司 靶向共有抗原之抗原結合蛋白
CN110305217B (zh) 2018-03-27 2022-03-29 广州爱思迈生物医药科技有限公司 双特异性抗体及其应用
WO2019197610A1 (en) 2018-04-13 2019-10-17 INSERM (Institut National de la Santé et de la Recherche Médicale) New vaccinal strategy
US11702450B2 (en) * 2018-08-30 2023-07-18 Université de Montréal Proteogenomic-based method for identifying tumor-specific antigens
CN113105528B (zh) * 2020-01-13 2023-12-08 辽宁中健医药科技有限公司 一条肿瘤相关抗原ctl表位肽及其应用
EP4171619A4 (en) * 2020-06-26 2024-08-07 National Breast Cancer Coalition BREAST CANCER VACCINE
CN118792176A (zh) * 2024-07-24 2024-10-18 佳吾益(北京)科技有限公司 用于mhc新抗原肽发现及亲和分析的工程化细胞
WO2026020513A1 (en) * 2024-07-24 2026-01-29 Jwe (Beijing) Science Technology, Inc. Engineered cell for identifing mhc neoantigens

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1254376A (zh) * 1996-10-01 2000-05-24 杰龙公司 端粒酶逆转录酶
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
CN1270634A (zh) * 1997-07-01 2000-10-18 卡姆比亚生物系统有限责任公司 脊椎动物端粒酶基因和蛋白质及其用途
WO1999050392A1 (en) * 1998-03-31 1999-10-07 Geron Corporation Methods and compositions for eliciting an immune response to a telomerase antigen
FR2777909B1 (fr) 1998-04-24 2002-08-02 Pasteur Institut Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex
US7030211B1 (en) * 1998-07-08 2006-04-18 Gemvax As Antigenic peptides derived from telomerase
EP2169073B1 (en) 1999-10-11 2013-11-13 Institut Pasteur Vector for the preparation of immunotherapeutical compositions
WO2001027304A2 (en) 1999-10-12 2001-04-19 Institut Pasteur Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna
FR2862648B1 (fr) * 2003-11-21 2006-02-03 Biomerieux Sa Nouveau peptide immunogene et nouveaux epitopes et utilisations notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l 'hepatite c
CA2504451A1 (en) * 2004-08-10 2006-02-10 Geron Corporation Dendritic cell vaccines for treating cancer made from embryonic stem cells
EP1748067A1 (en) 2005-07-29 2007-01-31 Institut Pasteur Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes

Also Published As

Publication number Publication date
EP2626420A3 (en) 2013-10-30
WO2007014740A3 (en) 2007-05-03
JP2009502150A (ja) 2009-01-29
EP2626420B1 (en) 2016-06-22
US20100172878A1 (en) 2010-07-08
US9624479B2 (en) 2017-04-18
US20090175892A1 (en) 2009-07-09
DK1910529T3 (da) 2014-01-13
EP2626420A2 (en) 2013-08-14
DK2626420T3 (en) 2016-09-26
US8003773B2 (en) 2011-08-23
US20140056932A1 (en) 2014-02-27
EP1910529A2 (en) 2008-04-16
CA2616674C (en) 2018-09-04
EP1748067A1 (en) 2007-01-31
CA2616674A1 (en) 2007-02-08
ES2440768T3 (es) 2014-01-30
EP1910529B1 (en) 2013-10-16
JP2016104031A (ja) 2016-06-09
PT2626420T (pt) 2016-09-28
JP5931812B2 (ja) 2016-06-08
WO2007014740A2 (en) 2007-02-08
ES2590462T3 (es) 2016-11-22
JP2013230164A (ja) 2013-11-14
JP5631545B2 (ja) 2014-11-26
JP5836202B2 (ja) 2015-12-24
US8858931B2 (en) 2014-10-14
JP6257667B2 (ja) 2018-01-10
JP2012183076A (ja) 2012-09-27

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