PL2640711T3 - Ulepszony sposób otrzymywania rufinamidu - Google Patents
Ulepszony sposób otrzymywania rufinamiduInfo
- Publication number
- PL2640711T3 PL2640711T3 PL11819524T PL11819524T PL2640711T3 PL 2640711 T3 PL2640711 T3 PL 2640711T3 PL 11819524 T PL11819524 T PL 11819524T PL 11819524 T PL11819524 T PL 11819524T PL 2640711 T3 PL2640711 T3 PL 2640711T3
- Authority
- PL
- Poland
- Prior art keywords
- rufinamide
- preparation
- improved process
- improved
- Prior art date
Links
- POGQSBRIGCQNEG-UHFFFAOYSA-N rufinamide Chemical compound N1=NC(C(=O)N)=CN1CC1=C(F)C=CC=C1F POGQSBRIGCQNEG-UHFFFAOYSA-N 0.000 title 1
- 229960003014 rufinamide Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/58—Preparation of carboxylic acid halides
- C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2458CH2010 | 2010-08-25 | ||
| EP11819524.7A EP2640711B1 (en) | 2010-08-25 | 2011-08-23 | Improved process for the preparation of rufinamide |
| PCT/IN2011/000561 WO2012025936A2 (en) | 2010-08-25 | 2011-08-23 | Improved process for the preparation of rufinamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2640711T3 true PL2640711T3 (pl) | 2016-06-30 |
Family
ID=45723872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11819524T PL2640711T3 (pl) | 2010-08-25 | 2011-08-23 | Ulepszony sposób otrzymywania rufinamidu |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8871945B2 (pl) |
| EP (1) | EP2640711B1 (pl) |
| JP (1) | JP6108112B2 (pl) |
| PL (1) | PL2640711T3 (pl) |
| WO (1) | WO2012025936A2 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9511151B2 (en) | 2010-11-12 | 2016-12-06 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of cancer |
| US10988516B2 (en) | 2012-03-26 | 2021-04-27 | Uti Limited Partnership | Methods and compositions for treating inflammation |
| CN103539750A (zh) * | 2012-07-09 | 2014-01-29 | 旭和（天津）医药科技有限公司 | 一种合成卢非酰胺的工艺 |
| US9603948B2 (en) | 2012-10-11 | 2017-03-28 | Uti Limited Partnership | Methods and compositions for treating multiple sclerosis and related disorders |
| WO2014072992A1 (en) | 2012-11-12 | 2014-05-15 | Aarti Industries Limited | A process for preparing triazole compounds |
| WO2014121383A1 (en) * | 2013-02-11 | 2014-08-14 | Apotex Technologies Inc. | A process for the preparation of rufinamide and intermediates thereof |
| SG10201803780UA (en) | 2013-11-04 | 2018-06-28 | Uti Lp | Methods and compositions for sustained immunotherapy |
| ES3055030T3 (en) | 2015-05-06 | 2026-02-09 | Uti Lp | Nanoparticle compositions for sustained therapy |
| EP3716949A4 (en) | 2017-11-29 | 2022-05-18 | UTI Limited Partnership | Methods of treating autoimmune disease |
| CN109096211B (zh) * | 2018-08-30 | 2021-11-23 | 华侨大学 | 一种多取代三氮唑衍生物的制备方法 |
| CN114106211A (zh) * | 2021-08-31 | 2022-03-01 | 海南医学院 | 一种云南鸡油菌多糖及其分离纯化方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1030332B (de) * | 1955-11-09 | 1958-05-22 | Basf Ag | Verfahren zur Herstellung von ª‡-Chloracrylsaeureestern |
| JPS596305B2 (ja) * | 1980-03-11 | 1984-02-10 | 工業技術院長 | １，２，３−トリアゾ−ル誘導体の製造方法 |
| US4789680A (en) | 1982-12-23 | 1988-12-06 | Ciba-Geigy Corporation | Aralkyltriazole compounds |
| DK0918758T3 (da) * | 1996-07-11 | 2002-08-19 | Novartis Ag | Fremgangsmåde til fremstilling af 1-substituerede 4-cyan-1,2,3-triazoler |
| JP2012505191A (ja) | 2008-10-13 | 2012-03-01 | シプラ・リミテッド | ルフィナマイドの製造方法 |
| EP2563766B1 (en) * | 2010-04-30 | 2014-06-25 | Laboratorios Lesvi, S.L. | Improved process for preparing rufinamide intermediate |
-
2011
- 2011-08-23 EP EP11819524.7A patent/EP2640711B1/en not_active Not-in-force
- 2011-08-23 US US13/818,660 patent/US8871945B2/en not_active Expired - Fee Related
- 2011-08-23 JP JP2013525423A patent/JP6108112B2/ja not_active Expired - Fee Related
- 2011-08-23 WO PCT/IN2011/000561 patent/WO2012025936A2/en not_active Ceased
- 2011-08-23 PL PL11819524T patent/PL2640711T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6108112B2 (ja) | 2017-04-05 |
| WO2012025936A3 (en) | 2012-04-19 |
| EP2640711B1 (en) | 2015-10-14 |
| EP2640711A2 (en) | 2013-09-25 |
| US8871945B2 (en) | 2014-10-28 |
| JP2013538208A (ja) | 2013-10-10 |
| WO2012025936A2 (en) | 2012-03-01 |
| US20130184469A1 (en) | 2013-07-18 |
| EP2640711A4 (en) | 2014-02-12 |
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