PL2646031T3 - Increasing drug bioavailability in naltrexone therapy - Google Patents

Increasing drug bioavailability in naltrexone therapy

Info

Publication number: PL2646031T3
Authority: PL; Poland
Prior art keywords: drug bioavailability; increasing drug; naltrexone therapy; naltrexone; therapy
Prior art date: 2010-12-03

Application number

PL11845186T

Other languages

Polish (pl)

Inventor

Shawn Flanagan

Eduardo Dunayevich

Original Assignee

Orexigen Therapeutics, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-12-03

Filing date

2011-12-02

Publication date

2017-08-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46172304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2646031(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-12-02 Application filed by Orexigen Therapeutics, Inc. filed Critical Orexigen Therapeutics, Inc.

2017-08-31 Publication of PL2646031T3 publication Critical patent/PL2646031T3/en

Links

229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 title 1
229960003086 naltrexone Drugs 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Physics & Mathematics (AREA)
Acoustics & Sound (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

PL11845186T 2010-12-03 2011-12-02 Increasing drug bioavailability in naltrexone therapy PL2646031T3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US41939510P	2010-12-03	2010-12-03

Publications (1)

Publication Number	Publication Date
PL2646031T3 true PL2646031T3 (en)	2017-08-31

Family

ID=46172304

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
PL17156985T PL3222280T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy
PL11845186T PL2646031T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy
PL23209711.3T PL4349369T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy
PL21152314.7T PL3884947T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL17156985T PL3222280T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
PL23209711.3T PL4349369T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy
PL21152314.7T PL3884947T3 (en)	2010-12-03	2011-12-02	Increasing drug bioavailability in naltrexone therapy

Country Status (27)

Country	Link
US (1)	US20130245056A1 (en)
EP (5)	EP2646031B9 (en)
JP (5)	JP6008866B2 (en)
KR (5)	KR20140035320A (en)
CN (1)	CN103313711A (en)
AR (2)	AR093182A1 (en)
AU (2)	AU2011336304B2 (en)
BR (1)	BR112013013390A2 (en)
CA (2)	CA3239386A1 (en)
CL (1)	CL2013001564A1 (en)
CY (2)	CY1118968T1 (en)
DK (4)	DK4349369T3 (en)
ES (3)	ES2866879T3 (en)
FI (2)	FI3884947T3 (en)
HR (4)	HRP20170734T1 (en)
HU (3)	HUE065852T2 (en)
IL (3)	IL226504B (en)
LT (4)	LT2646031T (en)
MX (2)	MX384662B (en)
PL (4)	PL3222280T3 (en)
PT (4)	PT3884947T (en)
RS (4)	RS65198B1 (en)
RU (1)	RU2640561C2 (en)
SI (4)	SI3884947T1 (en)
SM (4)	SMT202100227T1 (en)
TW (1)	TWI618536B (en)
WO (1)	WO2012075459A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004096201A1 (en)	2003-04-29	2004-11-11	Orexigen Therapeutics, Inc.	Compositions for affecting weight loss
ES2761812T3 (en)	2005-11-22	2020-05-21	Nalpropion Pharmaceuticals Inc	Composition and methods of increasing insulin sensitivity
WO2007089318A2 (en) *	2005-11-23	2007-08-09	Orexigen Therapeutics, Inc.	Compositions and methods for reducing food cravings
WO2009158114A1 (en)	2008-05-30	2009-12-30	Orexigen Therapeutics, Inc.	Methods for treating visceral fat conditions
CN102724878A (en)	2010-01-11	2012-10-10	奥雷西根治疗公司	Approach to providing weight loss therapy in patients with major depressive disorder
PL3222280T3 (en) *	2010-12-03	2021-11-29	Nalpropion Pharmaceuticals Llc	Increasing drug bioavailability in naltrexone therapy
HUE072188T2 (en)	2012-06-06	2025-10-28	Nalpropion Pharmaceuticals Llc	Preparation for use in a procedure for the treatment of overweight and obese patients at high cardiovascular risk
WO2016125109A1 (en) *	2015-02-07	2016-08-11	Intas Pharmaceuticals Ltd.	Pharmaceutical composition for the treatment of obesity
EP3600433B1 (en) *	2017-03-28	2021-05-05	LDN Pharma Limited	An agent that increases the expresssion of the bcl2-associated agonist of cell death for the treatment of cancer
EP3482751A1 (en) *	2017-11-14	2019-05-15	LDN Pharma Limited	Cancer treatment
US12303604B1 (en) *	2024-10-16	2025-05-20	Currax Pharmaceuticals Llc	Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10129265A1 (en) *	2001-06-18	2003-01-02	Hf Arzneimittelforsch Gmbh	Active ingredient combination for drug addiction or intoxicant therapy
US6972291B2 (en) *	2002-07-02	2005-12-06	Bernstein Richard K	Method for reducing food intake
EP1772147A2 (en) *	2003-03-17	2007-04-11	Japan Tobacco, Inc.	Method for increasing the oral bioavailability of S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate
WO2004096201A1 (en) *	2003-04-29	2004-11-11	Orexigen Therapeutics, Inc.	Compositions for affecting weight loss
WO2007016108A1 (en)	2005-07-27	2007-02-08	Orexigen Therapeutics, Inc.	Compositions for affecting weight loss
US8921344B2 (en) *	2006-11-03	2014-12-30	Salix Pharmaceuticals, Inc.	Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
ES2761812T3 (en)	2005-11-22	2020-05-21	Nalpropion Pharmaceuticals Inc	Composition and methods of increasing insulin sensitivity
WO2007089318A2 (en)	2005-11-23	2007-08-09	Orexigen Therapeutics, Inc.	Compositions and methods for reducing food cravings
US20070179168A1 (en)	2005-11-28	2007-08-02	Orexigen Therapeutics, Inc.	Methods of treating anxiety disorders
US8916195B2 (en)	2006-06-05	2014-12-23	Orexigen Therapeutics, Inc.	Sustained release formulation of naltrexone
KR101486228B1 (en) *	2006-06-19	2015-01-26	알파마 파머슈티컬스 엘엘씨	Pharmaceutical composition
KR101264789B1 (en) *	2006-06-30	2013-05-15	엘지디스플레이 주식회사	An array substrate for in plan switching LCD and method of fabricating of the same
WO2008011150A1 (en) *	2006-07-20	2008-01-24	Somaxon Pharmaceuticals, Inc.	Methods of improving the pharmacokinetics of doxepin
KR20150082689A (en)	2006-11-09	2015-07-15	오렉시젠 세러퓨틱스 인크.	Unit dosage packages
DK2089005T3 (en)	2006-11-09	2010-07-19	Orexigen Therapeutics Inc	Layered pharmaceutical formulations comprising a rapidly dissolving intermediate layer
SI3461503T1 (en) *	2007-04-11	2022-04-29	Biomarin Pharmaceutical Inc.	Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring
DE102007036076A1 (en)	2007-08-01	2009-02-05	Bayer Healthcare Aktiengesellschaft	Dipeptoid Produgs and their use
WO2009035473A2 (en) *	2007-09-13	2009-03-19	Sanfilippo Louis C	Method of treating binge eating disorder, obesity resulting from binge eating behavior and depressive disorders
WO2009158114A1 (en)	2008-05-30	2009-12-30	Orexigen Therapeutics, Inc.	Methods for treating visceral fat conditions
PL3222280T3 (en)	2010-12-03	2021-11-29	Nalpropion Pharmaceuticals Llc	Increasing drug bioavailability in naltrexone therapy

2011
- 2011-12-02 PL PL17156985T patent/PL3222280T3/en unknown
- 2011-12-02 MX MX2017013169A patent/MX384662B/en unknown
- 2011-12-02 WO PCT/US2011/063177 patent/WO2012075459A1/en not_active Ceased
- 2011-12-02 PL PL11845186T patent/PL2646031T3/en unknown
- 2011-12-02 AR ARP110104512A patent/AR093182A1/en not_active Application Discontinuation
- 2011-12-02 LT LTEP11845186.3T patent/LT2646031T/en unknown
- 2011-12-02 CA CA3239386A patent/CA3239386A1/en active Pending
- 2011-12-02 SM SM20210227T patent/SMT202100227T1/en unknown
- 2011-12-02 LT LTEP21152314.7T patent/LT3884947T/en unknown
- 2011-12-02 DK DK23209711.3T patent/DK4349369T3/en active
- 2011-12-02 ES ES17156985T patent/ES2866879T3/en active Active
- 2011-12-02 EP EP11845186.3A patent/EP2646031B9/en active Active
- 2011-12-02 SI SI201132102T patent/SI3884947T1/en unknown
- 2011-12-02 CA CA2819262A patent/CA2819262C/en active Active
- 2011-12-02 KR KR1020137017317A patent/KR20140035320A/en not_active Ceased
- 2011-12-02 RS RS20240196A patent/RS65198B1/en unknown
- 2011-12-02 KR KR1020217015625A patent/KR102391511B1/en active Active
- 2011-12-02 PT PT211523147T patent/PT3884947T/en unknown
- 2011-12-02 KR KR1020197014576A patent/KR102105857B1/en active Active
- 2011-12-02 AU AU2011336304A patent/AU2011336304B2/en active Active
- 2011-12-02 BR BR112013013390A patent/BR112013013390A2/en not_active Application Discontinuation
- 2011-12-02 SI SI201132141T patent/SI4349369T1/en unknown
- 2011-12-02 EP EP21152314.7A patent/EP3884947B1/en active Active
- 2011-12-02 RS RS20210469A patent/RS62149B1/en unknown
- 2011-12-02 HU HUE21152314A patent/HUE065852T2/en unknown
- 2011-12-02 HU HUE11845186A patent/HUE034393T2/en unknown
- 2011-12-02 ES ES11845186.3T patent/ES2625527T3/en active Active
- 2011-12-02 MX MX2013006071A patent/MX356801B/en active IP Right Grant
- 2011-12-02 LT LTEP23209711.3T patent/LT4349369T/en unknown
- 2011-12-02 US US13/991,137 patent/US20130245056A1/en not_active Abandoned
- 2011-12-02 DK DK17156985.8T patent/DK3222280T3/en active
- 2011-12-02 RU RU2013127423A patent/RU2640561C2/en active
- 2011-12-02 PT PT118451863T patent/PT2646031T/en unknown
- 2011-12-02 FI FIEP21152314.7T patent/FI3884947T3/en active
- 2011-12-02 JP JP2013542229A patent/JP6008866B2/en active Active
- 2011-12-02 KR KR1020207011510A patent/KR102258043B1/en active Active
- 2011-12-02 RS RS20251278A patent/RS67527B1/en unknown
- 2011-12-02 SM SM20240038T patent/SMT202400038T1/en unknown
- 2011-12-02 PT PT232097113T patent/PT4349369T/en unknown
- 2011-12-02 KR KR1020187016354A patent/KR101984500B1/en active Active
- 2011-12-02 SI SI201131967T patent/SI3222280T1/en unknown
- 2011-12-02 RS RS20170491A patent/RS56014B1/en unknown
- 2011-12-02 HR HRP20170734TT patent/HRP20170734T1/en unknown
- 2011-12-02 HR HRP20240115TT patent/HRP20240115T1/en unknown
- 2011-12-02 EP EP25202419.5A patent/EP4696322A3/en active Pending
- 2011-12-02 EP EP23209711.3A patent/EP4349369B1/en active Active
- 2011-12-02 CN CN2011800638854A patent/CN103313711A/en active Pending
- 2011-12-02 ES ES23209711T patent/ES3056642T3/en active Active
- 2011-12-02 HR HRP20251576TT patent/HRP20251576T1/en unknown
- 2011-12-02 TW TW100144442A patent/TWI618536B/en active
- 2011-12-02 PL PL23209711.3T patent/PL4349369T3/en unknown
- 2011-12-02 FI FIEP23209711.3T patent/FI4349369T3/en active
- 2011-12-02 SM SM20170232T patent/SMT201700232T1/en unknown
- 2011-12-02 LT LTEP17156985.8T patent/LT3222280T/en unknown
- 2011-12-02 DK DK11845186.3T patent/DK2646031T3/en active
- 2011-12-02 PL PL21152314.7T patent/PL3884947T3/en unknown
- 2011-12-02 PT PT171569858T patent/PT3222280T/en unknown
- 2011-12-02 SM SM20250474T patent/SMT202500474T1/en unknown
- 2011-12-02 SI SI201131199A patent/SI2646031T1/en unknown
- 2011-12-02 HU HUE17156985A patent/HUE053831T2/en unknown
- 2011-12-02 EP EP17156985.8A patent/EP3222280B1/en active Active
- 2011-12-02 DK DK21152314.7T patent/DK3884947T3/en active
2013
- 2013-05-23 IL IL226504A patent/IL226504B/en active IP Right Grant
- 2013-05-31 CL CL2013001564A patent/CL2013001564A1/en unknown
2016
- 2016-09-12 JP JP2016177391A patent/JP6456890B2/en active Active
2017
- 2017-05-18 CY CY20171100524T patent/CY1118968T1/en unknown
- 2017-06-26 AU AU2017204309A patent/AU2017204309A1/en not_active Abandoned
2018
- 2018-12-19 JP JP2018237245A patent/JP7025319B2/en active Active
2019
- 2019-11-21 IL IL270841A patent/IL270841A/en unknown
2020
- 2020-12-21 IL IL279626A patent/IL279626A/en unknown
2021
- 2021-04-19 CY CY20211100340T patent/CY1124331T1/en unknown
- 2021-04-19 HR HRP20210618TT patent/HRP20210618T1/en unknown
- 2021-12-23 AR ARP210103655A patent/AR124500A2/en unknown
2022
- 2022-02-10 JP JP2022019546A patent/JP2022060331A/en active Pending
2024
- 2024-03-27 JP JP2024051334A patent/JP2024071605A/en active Pending

Also Published As

Publication number	Publication date
JP2019056004A (en)	2019-04-11
TW201304780A (en)	2013-02-01
FI4349369T3 (en)	2025-12-17
SMT201700232T1 (en)	2017-07-18
IL279626A (en)	2021-03-01
KR101984500B1 (en)	2019-05-31
EP3884947A1 (en)	2021-09-29
FI3884947T3 (en)	2024-01-30
JP2024071605A (en)	2024-05-24
US20130245056A1 (en)	2013-09-19
EP4349369B1 (en)	2025-09-17
DK4349369T3 (en)	2025-12-22
RU2013127423A (en)	2015-01-10
ES3056642T3 (en)	2026-02-23
ES2625527T9 (en)	2018-09-25
HRP20251576T1 (en)	2026-01-30
DK3222280T3 (en)	2021-04-19
AU2011336304B2 (en)	2017-03-30
EP2646031B9 (en)	2018-01-10
PL3222280T3 (en)	2021-11-29
JP2022060331A (en)	2022-04-14
ES2625527T3 (en)	2017-07-19
KR20140035320A (en)	2014-03-21
KR102105857B1 (en)	2020-05-04
HUE053831T2 (en)	2021-07-28
KR20180069089A (en)	2018-06-22
MX384662B (en)	2025-03-14
KR20200044158A (en)	2020-04-28
IL226504B (en)	2021-01-31
HUE034393T2 (en)	2018-02-28
EP3222280A1 (en)	2017-09-27
AR124500A2 (en)	2023-04-05
IL270841A (en)	2020-01-30
JP6008866B2 (en)	2016-10-19
HRP20170734T1 (en)	2017-08-11
CY1124331T1 (en)	2022-07-22
CY1118968T1 (en)	2018-01-10
PT2646031T (en)	2017-05-25
KR102258043B1 (en)	2021-05-28
KR102391511B1 (en)	2022-04-26
DK2646031T3 (en)	2017-05-22
RU2640561C2 (en)	2018-01-09
HRP20210618T1 (en)	2021-09-17
AU2011336304A1 (en)	2013-07-11
LT3884947T (en)	2024-03-12
BR112013013390A2 (en)	2016-09-06
CA2819262A1 (en)	2012-06-07
JP6456890B2 (en)	2019-01-23
KR20190058702A (en)	2019-05-29
EP3884947B1 (en)	2023-11-15
CA3239386A1 (en)	2012-06-07
EP4349369A2 (en)	2024-04-10
AU2017204309A1 (en)	2017-07-13
PL3884947T3 (en)	2024-05-06
SI3222280T1 (en)	2021-11-30
EP4696322A2 (en)	2026-02-18
CN103313711A (en)	2013-09-18
EP4696322A3 (en)	2026-04-15
PL4349369T3 (en)	2026-03-23
EP3222280B1 (en)	2021-01-20
RU2017144631A3 (en)	2021-04-13
TWI618536B (en)	2018-03-21
AR093182A1 (en)	2015-05-27
CA2819262C (en)	2024-05-28
HRP20240115T1 (en)	2024-06-07
JP7025319B2 (en)	2022-02-24
MX356801B (en)	2018-06-13
RS67527B1 (en)	2026-01-30
EP2646031A4 (en)	2014-04-23
RS56014B1 (en)	2017-09-29
PT3222280T (en)	2021-04-22
SMT202500474T1 (en)	2026-01-12
MX2013006071A (en)	2013-10-01
RS65198B1 (en)	2024-03-29
SI3884947T1 (en)	2024-06-28
RU2017144631A (en)	2019-02-18
PT4349369T (en)	2025-12-17
SMT202400038T1 (en)	2024-03-13
SMT202100227T1 (en)	2021-07-12
LT3222280T (en)	2021-05-10
EP4349369A3 (en)	2024-05-15
SI2646031T1 (en)	2017-07-31
WO2012075459A1 (en)	2012-06-07
KR20210063473A (en)	2021-06-01
LT2646031T (en)	2017-06-26
JP2016210809A (en)	2016-12-15
DK3884947T3 (en)	2024-01-22
EP2646031B1 (en)	2017-02-22
HUE065852T2 (en)	2024-06-28
EP2646031A1 (en)	2013-10-09
LT4349369T (en)	2026-01-12
SI4349369T1 (en)	2026-02-27
JP2013544290A (en)	2013-12-12
RS62149B1 (en)	2021-08-31
PT3884947T (en)	2024-02-16
ES2866879T3 (en)	2021-10-20
CL2013001564A1 (en)	2014-05-02

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SG10201700715SA (en)	2017-02-27	Drug delivery device
PL2560624T3 (en)	2019-01-31	Therapeutic formulation for reduced drug side effects
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GB201019527D0 (en)	2010-12-29	Redox drug derivatives
GB201006112D0 (en)	2010-05-26	Redox drug derivatives