PL2657233T3 - 3,5-dipodstawiony związek alkinylobenzenowy i jego sól - Google Patents

3,5-dipodstawiony związek alkinylobenzenowy i jego sól

Info

Publication number
PL2657233T3
PL2657233T3 PL13728918T PL13728918T PL2657233T3 PL 2657233 T3 PL2657233 T3 PL 2657233T3 PL 13728918 T PL13728918 T PL 13728918T PL 13728918 T PL13728918 T PL 13728918T PL 2657233 T3 PL2657233 T3 PL 2657233T3
Authority
PL
Poland
Prior art keywords
disubstituted
salt
alkynylbenzene
compound
alkynylbenzene compound
Prior art date
Application number
PL13728918T
Other languages
English (en)
Inventor
Takeshi Sagara
Satoru Ito
Sachie Otsuki
Hiroshi Sootome
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of PL2657233T3 publication Critical patent/PL2657233T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
PL13728918T 2012-01-19 2013-01-17 3,5-dipodstawiony związek alkinylobenzenowy i jego sól PL2657233T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012009467 2012-01-19
PCT/JP2013/050740 WO2013108809A1 (ja) 2012-01-19 2013-01-17 ３，５－二置換ベンゼンアルキニル化合物及びその塩
EP13728918.7A EP2657233B1 (en) 2012-01-19 2013-01-17 3,5-disubstituted alkynylbenzene compound and salt thereof

Publications (1)

Publication Number Publication Date
PL2657233T3 true PL2657233T3 (pl) 2015-01-30

Family

ID=48799233

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13728918T PL2657233T3 (pl) 2012-01-19 2013-01-17 3,5-dipodstawiony związek alkinylobenzenowy i jego sól

Country Status (23)

Country Link
US (1) US9108973B2 (pl)
EP (1) EP2657233B1 (pl)
JP (1) JP5355825B1 (pl)
KR (1) KR101623286B1 (pl)
CN (1) CN103958512B (pl)
AU (1) AU2013210403B2 (pl)
BR (1) BR112014017749B1 (pl)
CA (1) CA2854093C (pl)
DK (1) DK2657233T3 (pl)
ES (1) ES2516392T3 (pl)
FI (1) FIC20230038I1 (pl)
FR (1) FR23C1050I2 (pl)
HU (1) HUS2300043I1 (pl)
MX (1) MX351513B (pl)
MY (1) MY171055A (pl)
NL (1) NL301254I2 (pl)
NO (1) NO2023046I1 (pl)
PL (1) PL2657233T3 (pl)
PT (1) PT2657233E (pl)
RU (1) RU2576384C1 (pl)
SG (1) SG2014009286A (pl)
TW (1) TWI508964B (pl)
WO (1) WO2013108809A1 (pl)

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US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
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US9580423B2 (en) 2015-02-20 2017-02-28 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
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JP6141568B1 (ja) 2015-09-01 2017-06-07 大鵬薬品工業株式会社 新規なピラゾロ［３，４−ｄ］ピリミジン化合物又はその塩
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CN107344940B (zh) * 2016-05-06 2020-04-21 广东东阳光药业有限公司 Btk抑制剂及其用途
CN107698593A (zh) * 2016-08-09 2018-02-16 南京天印健华医药科技有限公司 作为fgfr抑制剂的杂环化合物
WO2018159613A1 (ja) * 2017-02-28 2018-09-07 大鵬薬品工業株式会社 ピラゾロ［３，４－ｄ］ピリミジン化合物を用いた抗腫瘍効果増強剤
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WO2020110974A1 (ja) 2018-11-26 2020-06-04 大鵬薬品工業株式会社 線維芽細胞増殖因子受容体阻害剤と内分泌療法との併用による内分泌療法が適用される腫瘍の治療及び予防方法
WO2020170355A1 (ja) * 2019-02-20 2020-08-27 大鵬薬品工業株式会社 Ｆｇｆｒ１変異腫瘍の治療方法
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JP2024509472A (ja) * 2021-03-08 2024-03-01 大鵬薬品工業株式会社 Ｆｇｆｒ２及び癌ドライバー遺伝子に遺伝子変化が同時発生する患者におけるがんの治療
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CN115785103A (zh) * 2022-12-28 2023-03-14 北京康立生医药技术开发有限公司 一种治疗胆管癌药物福巴替尼的合成方法
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Also Published As

Publication number Publication date
ES2516392T3 (es) 2014-10-30
PT2657233E (pt) 2014-10-24
NL301254I1 (pl) 2023-12-20
MY171055A (en) 2019-09-23
AU2013210403A1 (en) 2014-06-26
BR112014017749A2 (pt) 2017-06-20
CN103958512B (zh) 2016-01-20
TW201335156A (zh) 2013-09-01
SG2014009286A (en) 2014-04-28
KR20140080551A (ko) 2014-06-30
AU2013210403B2 (en) 2016-01-14
MX351513B (es) 2017-10-17
EP2657233B1 (en) 2014-08-27
US9108973B2 (en) 2015-08-18
CN103958512A (zh) 2014-07-30
FIC20230038I1 (fi) 2023-12-18
CA2854093C (en) 2016-07-05
CA2854093A1 (en) 2013-07-25
FR23C1050I2 (fr) 2024-12-13
MX2014008605A (es) 2014-08-27
KR101623286B1 (ko) 2016-05-20
BR112014017749B1 (pt) 2021-08-03
WO2013108809A1 (ja) 2013-07-25
TWI508964B (zh) 2015-11-21
NL301254I2 (nl) 2024-01-10
RU2576384C1 (ru) 2016-03-10
BR112014017749A8 (pt) 2017-07-11
JP5355825B1 (ja) 2013-11-27
EP2657233A4 (en) 2013-12-04
FR23C1050I1 (fr) 2024-01-26
NO2023046I1 (no) 2023-12-20
EP2657233A1 (en) 2013-10-30
HK1198164A1 (zh) 2015-03-13
US20140343035A1 (en) 2014-11-20
JPWO2013108809A1 (ja) 2015-05-11
HUS2300043I1 (hu) 2024-01-28
DK2657233T3 (da) 2014-09-22

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