|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
JP5873656B2
(ja)
|
2011-06-13 |
2016-03-01 |
株式会社Ihi |
金属サレン錯体化合物、局所麻酔薬剤及び抗悪性腫瘍薬剤
|
|
CA2876689C
(en)
|
2012-06-13 |
2022-04-26 |
Incyte Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
NZ703495A
(en)
|
2012-07-11 |
2018-02-23 |
Blueprint Medicines Corp |
Inhibitors of the fibroblast growth factor receptor
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
AR094812A1
(es)
|
2013-02-20 |
2015-08-26 |
Eisai R&D Man Co Ltd |
Derivado de piridina monocíclico como inhibidor del fgfr
|
|
PH12015502383B1
(en)
|
2013-04-19 |
2023-02-03 |
Incyte Holdings Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
DK3023100T3
(da)
*
|
2013-07-18 |
2019-05-27 |
Taiho Pharmaceutical Co Ltd |
Antitumorlægemiddel til intermitterende administration af fgfr-hæmmer
|
|
JP6084292B2
(ja)
|
2013-07-18 |
2017-02-22 |
大鵬薬品工業株式会社 |
Ｆｇｆｒ阻害剤耐性癌の治療薬
|
|
MX360498B
(es)
|
2013-08-12 |
2018-11-05 |
Taiho Pharmaceutical Co Ltd |
Compuesto novedoso de pirimidina fusionada o sal del mismo.
|
|
PT3395814T
(pt)
|
2013-10-25 |
2022-07-27 |
Blueprint Medicines Corp |
Inibidores do recetor do fator de crescimento de fibroblastos
|
|
WO2015099127A1
(ja)
*
|
2013-12-27 |
2015-07-02 |
中外製薬株式会社 |
Ｆｇｆｒゲートキーパー変異遺伝子およびそれを標的とする医薬
|
|
WO2015108992A1
(en)
|
2014-01-15 |
2015-07-23 |
Blueprint Medicines Corporation |
Heterobicyclic compounds and their use as fgfr4 receptor inhibitors
|
|
CN106661031B
(zh)
*
|
2014-06-24 |
2019-07-23 |
大鹏药品工业株式会社 |
吡咯并嘧啶化合物或其盐、含有其的药物组合物及应用
|
|
WO2016027781A1
(ja)
|
2014-08-18 |
2016-02-25 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
単環ピリジン誘導体の塩およびその結晶
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
CN105837575B
(zh)
*
|
2015-01-13 |
2019-01-15 |
四川大学 |
3-乙炔基吡唑并嘧啶衍生物及其制备方法和用途
|
|
DK3120852T3
(da)
*
|
2015-01-30 |
2019-07-29 |
Taiho Pharmaceutical Co Ltd |
Præventivt og/eller terapeutisk middel til immunsygdomme
|
|
CA2976790C
(en)
|
2015-02-20 |
2024-02-27 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
US9580423B2
(en)
|
2015-02-20 |
2017-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
CN114984013A
(zh)
|
2015-03-25 |
2022-09-02 |
国立癌症研究中心 |
胆管癌治疗剂
|
|
US10434103B2
(en)
*
|
2015-03-31 |
2019-10-08 |
Taiho Pharmaceutical Co., Ltd. |
Crystal of 3,5-disubstituted benzene alkynyl compound
|
|
JP6762300B2
(ja)
|
2015-06-17 |
2020-09-30 |
中外製薬株式会社 |
アミノピラゾール誘導体
|
|
KR102075886B1
(ko)
|
2015-09-01 |
2020-02-11 |
다이호야쿠힌고교 가부시키가이샤 |
신규한 피라졸로[3,4-d]피리미딘 화합물 또는 그 염
|
|
AU2016374441B2
(en)
|
2015-12-17 |
2021-10-21 |
Eisai R&D Management Co., Ltd. |
Therapeutic agent for breast cancer
|
|
TWI623316B
(zh)
*
|
2015-12-22 |
2018-05-11 |
Taiho Pharmaceutical Co Ltd |
Antitumor effect enhancer derived from pyrrolopyrimidine compound
|
|
DK3269370T3
(da)
*
|
2016-02-23 |
2020-04-06 |
Taiho Pharmaceutical Co Ltd |
Hidtil ukendt kondenseret pyrimidinforbindelse eller salt deraf
|
|
US11883404B2
(en)
*
|
2016-03-04 |
2024-01-30 |
Taiho Pharmaceuticals Co., Ltd. |
Preparation and composition for treatment of malignant tumors
|
|
KR20250007056A
(ko)
|
2016-03-04 |
2025-01-13 |
다이호야쿠힌고교 가부시키가이샤 |
악성 종양 치료용 제제 및 조성물
|
|
CN107344940B
(zh)
*
|
2016-05-06 |
2020-04-21 |
广东东阳光药业有限公司 |
Btk抑制剂及其用途
|
|
CN107698593A
(zh)
*
|
2016-08-09 |
2018-02-16 |
南京天印健华医药科技有限公司 |
作为fgfr抑制剂的杂环化合物
|
|
JP7223684B2
(ja)
*
|
2017-02-28 |
2023-02-16 |
大鵬薬品工業株式会社 |
ピラゾロ［３，４－ｄ］ピリミジン化合物を用いた抗腫瘍効果増強剤
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
KR20190043437A
(ko)
|
2017-10-18 |
2019-04-26 |
씨제이헬스케어 주식회사 |
단백질 키나제 억제제로서의 헤테로고리 화합물
|
|
CN109776544B
(zh)
*
|
2017-11-15 |
2022-02-01 |
上海医药工业研究院 |
吡唑并[3,4-d]嘧啶类化合物及其制备方法和用途
|
|
US11833151B2
(en)
|
2018-03-19 |
2023-12-05 |
Taiho Pharmaceutical Co., Ltd. |
Pharmaceutical composition including sodium alkyl sulfate
|
|
BR112020017922A2
(pt)
|
2018-03-28 |
2020-12-22 |
Eisai R&D Management Co., Ltd. |
Agente terapêutico para carcinoma hepatocelular
|
|
RS66310B1
(sr)
|
2018-05-04 |
2025-01-31 |
Incyte Corp |
Čvrsti oblici inhibitora fgfr i procesi za njegovu pripremu
|
|
KR102956194B1
(ko)
|
2018-05-04 |
2026-04-23 |
인사이트 코포레이션 |
Fgfr 억제제의 염
|
|
WO2020007234A1
(zh)
*
|
2018-07-02 |
2020-01-09 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制蛋白激酶活性的炔基(杂)芳环类化合物
|
|
JP7161546B2
(ja)
*
|
2018-11-09 |
2022-10-26 |
大鵬薬品工業株式会社 |
ジメトキシベンゼン化合物の類縁物質、該化合物の分析方法及び標準品
|
|
AU2018448845B2
(en)
*
|
2018-11-09 |
2022-03-24 |
Taiho Pharmaceutical Co., Ltd. |
Method for producing dimethoxybenzene compound
|
|
KR102195348B1
(ko)
|
2018-11-15 |
2020-12-24 |
에이치케이이노엔 주식회사 |
단백질 키나제 억제제로서의 신규 화합물 및 이를 포함하는 약제학적 조성물
|
|
US20220023300A1
(en)
*
|
2018-11-26 |
2022-01-27 |
Taiho Pharmaceutical Co., Ltd. |
Therapeutic and prophylactic method for tumor treatable with endocrine therapy by combined use of fibroblast growth factor receptor inhibitor with endocrine therapy
|
|
WO2020170355A1
(ja)
*
|
2019-02-20 |
2020-08-27 |
大鵬薬品工業株式会社 |
Ｆｇｆｒ１変異腫瘍の治療方法
|
|
EP3932425A4
(en)
*
|
2019-02-28 |
2022-12-07 |
Taiho Pharmaceutical Co., Ltd. |
CANCER THERAPY WITH 3,5-DISUBSTITUTED BENZENE ALKINYL COMPOUND AND IMMUNE CHECKPOINT INHIBITOR
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
CA3129665A1
(en)
|
2019-03-21 |
2020-09-24 |
Onxeo |
A dbait molecule in combination with kinase inhibitor for the treatment of cancer
|
|
ES3065954T3
(en)
*
|
2019-05-13 |
2026-05-08 |
Relay Therapeutics Inc |
Fgfr inhibitors and methods of use thereof
|
|
JP2022533939A
(ja)
*
|
2019-05-17 |
2022-07-27 |
キネート バイオファーマ インク． |
線維芽細胞増殖因子受容体キナーゼの阻害剤
|
|
JP7574184B2
(ja)
|
2019-06-21 |
2024-10-28 |
大鵬薬品工業株式会社 |
悪性腫瘍の治療方法
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
GEP20247679B
(en)
|
2019-10-14 |
2024-10-10 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
CN114641293B
(zh)
*
|
2019-11-08 |
2024-05-31 |
石药集团中奇制药技术（石家庄）有限公司 |
一种fgfr抑制剂的用途
|
|
KR20220098759A
(ko)
|
2019-11-08 |
2022-07-12 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
키나제 억제제에 대해 내성을 획득한 암의 치료 방법
|
|
MX2022006691A
(es)
|
2019-12-04 |
2022-09-19 |
Incyte Corp |
Derivados de un inhibidor de receptores del factor de crecimiento de fibroblastos (fgfr).
|
|
WO2021113479A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021148581A1
(en)
|
2020-01-22 |
2021-07-29 |
Onxeo |
Novel dbait molecule and its use
|
|
WO2021153703A1
(ja)
|
2020-01-31 |
2021-08-05 |
国立大学法人京都大学 |
軟骨形成異常症の治療
|
|
CN116057045B
(zh)
|
2020-06-05 |
2026-06-09 |
金耐特生物制药公司 |
成纤维细胞生长因子受体激酶抑制剂
|
|
TW202216151A
(zh)
*
|
2020-07-15 |
2022-05-01 |
日商大鵬藥品工業股份有限公司 |
含有使用於腫瘤之治療之嘧啶化合物之組合
|
|
TWI797711B
(zh)
*
|
2020-08-13 |
2023-04-01 |
大陸商上海和譽生物醫藥科技有限公司 |
一種fgfr及其突變抑制劑，其製備方法和應用
|
|
WO2022042613A1
(zh)
*
|
2020-08-27 |
2022-03-03 |
上海和誉生物医药科技有限公司 |
一种1h-吡唑-4-酰胺衍生物，其制备方法和应用
|
|
TWI924727B
(zh)
|
2020-11-18 |
2026-05-11 |
美商傳達治療有限公司 |
Ｆｇｆｒ抑制劑及其製造及使用方法
|
|
CA3199714A1
(en)
*
|
2020-11-20 |
2022-05-27 |
Isao Miyazaki |
Brain-migrating tumor therapeutic agent containing fused pyrimidine compound as active ingredient
|
|
CN114805359B
(zh)
*
|
2021-01-28 |
2023-10-27 |
药雅科技(上海)有限公司 |
炔代杂环化合物fgfr抑制剂的制备方法和用途
|
|
CN115028634B
(zh)
*
|
2021-03-08 |
2023-11-28 |
药雅科技(上海)有限公司 |
一种炔代吡嗪并杂环类fgfr抑制剂及其制备方法和用途
|
|
JP2024509472A
(ja)
*
|
2021-03-08 |
2024-03-01 |
大鵬薬品工業株式会社 |
Ｆｇｆｒ２及び癌ドライバー遺伝子に遺伝子変化が同時発生する患者におけるがんの治療
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為ｆｇｆｒ抑制劑之三環雜環
|
|
CN115785103A
(zh)
*
|
2022-12-28 |
2023-03-14 |
北京康立生医药技术开发有限公司 |
一种治疗胆管癌药物福巴替尼的合成方法
|
|
WO2025046898A1
(ja)
|
2023-08-31 |
2025-03-06 |
大鵬薬品工業株式会社 |
３，５－二置換ベンゼンアルキニル化合物と免疫チェックポイント阻害薬を含む癌治療法
|
|
JPWO2025178019A1
(pl)
*
|
2024-02-19 |
2025-08-28 |
|
|
|
CN119080780A
(zh)
*
|
2024-08-29 |
2024-12-06 |
武汉九州钰民医药科技有限公司 |
一种富替巴替尼的制备方法
|
|
CN120172981B
(zh)
*
|
2025-05-20 |
2025-07-25 |
南京工业大学 |
一类以fgfr2为靶点的小分子降解剂及其药物组合物和应用
|