PL2678333T3 - Ulepszony sposób otrzymywania worykonazolu i jego produktów pośrednich - Google Patents
Ulepszony sposób otrzymywania worykonazolu i jego produktów pośrednichInfo
- Publication number
- PL2678333T3 PL2678333T3 PL12709178T PL12709178T PL2678333T3 PL 2678333 T3 PL2678333 T3 PL 2678333T3 PL 12709178 T PL12709178 T PL 12709178T PL 12709178 T PL12709178 T PL 12709178T PL 2678333 T3 PL2678333 T3 PL 2678333T3
- Authority
- PL
- Poland
- Prior art keywords
- voriconazole
- intermediates
- preparation
- improved process
- improved
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title 1
- BCEHBSKCWLPMDN-MGPLVRAMSA-N voriconazole Chemical compound C1([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)=NC=NC=C1F BCEHBSKCWLPMDN-MGPLVRAMSA-N 0.000 title 1
- 229960004740 voriconazole Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN433DE2011 | 2011-02-21 | ||
| EP12709178.3A EP2678333B1 (en) | 2011-02-21 | 2012-02-21 | An improved process for the preparation of voriconazole and intermediates thereof |
| PCT/IB2012/050791 WO2012114273A1 (en) | 2011-02-21 | 2012-02-21 | An improved process for the preparation of voriconazole and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2678333T3 true PL2678333T3 (pl) | 2015-08-31 |
Family
ID=46720174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12709178T PL2678333T3 (pl) | 2011-02-21 | 2012-02-21 | Ulepszony sposób otrzymywania worykonazolu i jego produktów pośrednich |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140350252A1 (pl) |
| EP (1) | EP2678333B1 (pl) |
| AU (1) | AU2012221788A1 (pl) |
| CA (1) | CA2827379A1 (pl) |
| PL (1) | PL2678333T3 (pl) |
| WO (1) | WO2012114273A1 (pl) |
| ZA (1) | ZA201306212B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102898419A (zh) * | 2012-11-15 | 2013-01-30 | 南京海陵中药制药工艺技术研究有限公司 | 一种制备伏立康唑中间体ⅰ的方法 |
| CN105277629A (zh) * | 2014-06-12 | 2016-01-27 | 陕西合成药业股份有限公司 | 一种分离分析伏立康唑磷酸酯或其药用盐异构体的hplc方法 |
| CN105699498B (zh) * | 2014-11-25 | 2020-06-12 | 陕西合成药业股份有限公司 | 一种分离分析伏立康唑磷酸酯或其药用盐有关物质的hplc方法 |
| CN105503834B (zh) | 2015-12-23 | 2021-03-05 | 浙江华海药业股份有限公司 | 一种伏立康唑中间体的合成方法 |
| CN111704606A (zh) * | 2020-06-11 | 2020-09-25 | 广东隆赋药业股份有限公司 | 一种伏立康唑中间体的制备方法 |
| CN112079819B (zh) * | 2020-09-24 | 2022-06-17 | 南京易亨制药有限公司 | 一种改进的伏立康唑消旋体制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8819308D0 (en) | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Triazole antifungal agents |
| GB9002375D0 (en) | 1990-02-02 | 1990-04-04 | Pfizer Ltd | Triazole antifungal agents |
| GB9516121D0 (en) | 1995-08-05 | 1995-10-04 | Pfizer Ltd | Organometallic addition to ketones |
-
2012
- 2012-02-21 AU AU2012221788A patent/AU2012221788A1/en not_active Abandoned
- 2012-02-21 EP EP12709178.3A patent/EP2678333B1/en active Active
- 2012-02-21 CA CA2827379A patent/CA2827379A1/en not_active Abandoned
- 2012-02-21 PL PL12709178T patent/PL2678333T3/pl unknown
- 2012-02-21 WO PCT/IB2012/050791 patent/WO2012114273A1/en not_active Ceased
- 2012-02-21 US US13/985,157 patent/US20140350252A1/en not_active Abandoned
-
2013
- 2013-08-19 ZA ZA2013/06212A patent/ZA201306212B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20140350252A1 (en) | 2014-11-27 |
| CA2827379A1 (en) | 2012-08-30 |
| EP2678333A1 (en) | 2014-01-01 |
| AU2012221788A1 (en) | 2013-09-05 |
| EP2678333B1 (en) | 2015-04-08 |
| ZA201306212B (en) | 2014-04-30 |
| WO2012114273A1 (en) | 2012-08-30 |
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