PL2682409T3 - Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowym - Google Patents
Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowymInfo
- Publication number
- PL2682409T3 PL2682409T3 PL12752403T PL12752403T PL2682409T3 PL 2682409 T3 PL2682409 T3 PL 2682409T3 PL 12752403 T PL12752403 T PL 12752403T PL 12752403 T PL12752403 T PL 12752403T PL 2682409 T3 PL2682409 T3 PL 2682409T3
- Authority
- PL
- Poland
- Prior art keywords
- derivative
- amino
- carboxylic acid
- hyaluronic acid
- modified
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011046749 | 2011-03-03 | ||
| EP12752403.1A EP2682409B1 (en) | 2011-03-03 | 2012-03-02 | Derivative of hyaluronic acid modified with amino-carboxylic acid |
| PCT/JP2012/055421 WO2012118189A1 (ja) | 2011-03-03 | 2012-03-02 | アミノ－カルボン酸により修飾されたヒアルロン酸誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2682409T3 true PL2682409T3 (pl) | 2017-12-29 |
Family
ID=46758114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12752403T PL2682409T3 (pl) | 2011-03-03 | 2012-03-02 | Pochodna kwasu hialuronowego zmodyfikowana kwasem aminokarboksylowym |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9243077B2 (pl) |
| EP (2) | EP2682409B1 (pl) |
| JP (2) | JP6141180B2 (pl) |
| DK (1) | DK2682409T3 (pl) |
| ES (1) | ES2635087T3 (pl) |
| HU (1) | HUE033169T2 (pl) |
| PL (1) | PL2682409T3 (pl) |
| SI (1) | SI2682409T1 (pl) |
| WO (1) | WO2012118189A1 (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11564971B2 (en) | 2012-09-05 | 2023-01-31 | Chugai Seiyaku Kabushiki Kaisha | Hyaluronic acid derivative having amino acid and steryl group introduced thereinto |
| US9572832B2 (en) * | 2013-08-29 | 2017-02-21 | Holy Stone Healthcare Co., Ltd. | Compound of glycosaminoglycan and its fabrication method as well as application |
| CN107207627B (zh) * | 2015-02-27 | 2022-05-24 | 学校法人常翔学园 | 具有膜透过性肽链的多糖衍生物 |
| JP6613300B2 (ja) * | 2015-03-31 | 2019-11-27 | キユーピー株式会社 | ヒアルロン酸誘導体およびその製造方法、ならびにヒアルロン酸誘導体を含む化粧料、食品組成物および医薬組成物 |
| EP3397649B1 (en) | 2015-12-29 | 2020-05-27 | Galderma S.A. | Method for preparing acylated crosslinked glycosaminoglycans |
| EP3252080A1 (en) * | 2016-05-31 | 2017-12-06 | Galderma S.A. | Method for preparing acylated crosslinked glycosaminoglycans |
| PT3623390T (pt) | 2016-05-31 | 2023-10-27 | Galderma Sa | Reticulador de hidrato de carbono |
| IL269506B2 (en) | 2017-03-22 | 2024-04-01 | Genentech Inc | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods |
| WO2019098393A1 (ja) * | 2017-11-15 | 2019-05-23 | 中外製薬株式会社 | ポリエチレングリコールにより修飾されたヒアルロン酸誘導体 |
| CN109206537B (zh) * | 2018-10-10 | 2021-04-09 | 华熙生物科技股份有限公司 | 一种乙酰化透明质酸钠的制备方法及其应用 |
| US11730691B2 (en) | 2019-12-02 | 2023-08-22 | Galderma Holding SA | High molecular weight esthetic compositions |
| CN114989455B (zh) * | 2022-06-16 | 2024-11-19 | 燕山大学 | 用于光固化载细胞3d打印复合水凝胶及其制备方法和应用 |
| KR20260034668A (ko) * | 2023-07-03 | 2026-03-11 | 셀라 테라퓨틱스, 엘엘씨 | 히알루론산 기반의 약물 전달 시스템 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174999B1 (en) | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
| US6610669B1 (en) * | 1987-09-18 | 2003-08-26 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
| US4937270A (en) * | 1987-09-18 | 1990-06-26 | Genzyme Corporation | Water insoluble derivatives of hyaluronic acid |
| JP2766303B2 (ja) | 1989-04-13 | 1998-06-18 | 生化学工業株式会社 | グリコサミノグリカンで修飾されたスーパーオキシドジスムターゼ及びその製造法 |
| CA2070672C (en) | 1990-10-18 | 2002-10-08 | Kazuo Akima | Compound of medicinal ingredient and hyaluronic acid and process for producing the same |
| JPH0585942A (ja) | 1991-02-26 | 1993-04-06 | Denki Kagaku Kogyo Kk | インターフエロン−ヒアルロン酸及び／又はその塩の結合体 |
| JP4018181B2 (ja) * | 1995-11-07 | 2007-12-05 | 生化学工業株式会社 | グリコサミノグリカン誘導体およびその製造法 |
| JP2001526181A (ja) | 1997-12-12 | 2001-12-18 | エクスプレション・ジェネティックス・インコーポレーテッド | 遺伝子輸送体であるグラフト共重合体 |
| ITPD980169A1 (it) | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
| US6630457B1 (en) | 1998-09-18 | 2003-10-07 | Orthogene Llc | Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same |
| AU6357900A (en) | 1999-07-20 | 2001-02-05 | Amgen, Inc. | Hyaluronic acid-protein conjugates, pharmaceutical compositions and related methods |
| JP2001081103A (ja) | 1999-09-13 | 2001-03-27 | Denki Kagaku Kogyo Kk | ヒアルロン酸結合薬剤 |
| WO2001060412A2 (en) | 2000-02-15 | 2001-08-23 | Genzyme Corporation | Modification of biopolymers for improved drug delivery |
| KR101121403B1 (ko) | 2003-09-08 | 2012-04-12 | 추가이 세이야쿠 가부시키가이샤 | 히알루론산 수식물, 및 그것을 사용한 약물 담체 |
| TW200526253A (en) * | 2003-11-14 | 2005-08-16 | Chugai Pharmaceutical Co Ltd | Cross-linked polysaccharide microparticles and process for producing the same |
| WO2005054302A1 (ja) * | 2003-12-05 | 2005-06-16 | Chugai Seiyaku Kabushiki Kaisha | 薬物担体及びその製造方法 |
| EP1790665B1 (en) | 2004-09-07 | 2014-11-05 | Chugai Seiyaku Kabushiki Kaisha | Process for producing water-soluble modified hyaluronic acid |
| TW200643033A (en) * | 2005-03-08 | 2006-12-16 | Chugai Pharmaceutical Co Ltd | Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue |
| US8258295B2 (en) * | 2007-04-30 | 2012-09-04 | Prometic Biosciences Inc. | Triazine derivatives, compositions containing such derivatives, and methods of treatment of cancer and autoimmune diseases using such derivatives |
| WO2010053140A1 (ja) | 2008-11-05 | 2010-05-14 | 国立大学法人 東京医科歯科大学 | ヒアルロン酸誘導体、およびその医薬組成物 |
| IT1399351B1 (it) | 2009-06-16 | 2013-04-16 | Fidia Farmaceutici | Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi |
| WO2011148116A2 (fr) | 2010-05-27 | 2011-12-01 | Laboratoire Idenov | Acide hyaluronique modifie, procede de fabrication et utilisations |
-
2012
- 2012-03-02 PL PL12752403T patent/PL2682409T3/pl unknown
- 2012-03-02 US US14/002,919 patent/US9243077B2/en active Active
- 2012-03-02 EP EP12752403.1A patent/EP2682409B1/en active Active
- 2012-03-02 DK DK12752403.1T patent/DK2682409T3/en active
- 2012-03-02 HU HUE12752403A patent/HUE033169T2/en unknown
- 2012-03-02 JP JP2013502420A patent/JP6141180B2/ja active Active
- 2012-03-02 SI SI201231008T patent/SI2682409T1/sl unknown
- 2012-03-02 ES ES12752403.1T patent/ES2635087T3/es active Active
- 2012-03-02 EP EP17152228.7A patent/EP3184553B1/en active Active
- 2012-03-02 WO PCT/JP2012/055421 patent/WO2012118189A1/ja not_active Ceased
-
2017
- 2017-05-01 JP JP2017091352A patent/JP2017179374A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK2682409T3 (en) | 2017-09-11 |
| EP2682409A1 (en) | 2014-01-08 |
| EP3184553B1 (en) | 2019-05-01 |
| HUE033169T2 (en) | 2017-11-28 |
| JP2017179374A (ja) | 2017-10-05 |
| EP3184553A1 (en) | 2017-06-28 |
| SI2682409T1 (sl) | 2017-08-31 |
| JPWO2012118189A1 (ja) | 2014-07-07 |
| JP6141180B2 (ja) | 2017-06-07 |
| US20130338352A1 (en) | 2013-12-19 |
| WO2012118189A1 (ja) | 2012-09-07 |
| ES2635087T3 (es) | 2017-10-02 |
| EP2682409A4 (en) | 2014-11-19 |
| EP2682409B1 (en) | 2017-07-05 |
| US9243077B2 (en) | 2016-01-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2682409T1 (sl) | Derivat hialuronske kisline modificiran z amino-karboksilno kislino | |
| SG11201500187WA (en) | Methods of manufacturing cartilage products | |
| GB201104096D0 (en) | Production of graphene | |
| EP2712362A4 (en) | MANUFACTURE OF LACTO-N-TETRAOSE | |
| PL2772490T3 (pl) | Aminoalkilo-podstawiona pochodna n-tienylobenzamidu | |
| GB201103499D0 (en) | Process | |
| GB201107072D0 (en) | Process | |
| ZA201402377B (en) | Electrolytic production of power | |
| SG11201402979PA (en) | Biotechnological production of 3-hydroxyisobutyric acid | |
| GB201101370D0 (en) | Process | |
| EP2875122A4 (en) | PROCESSES FOR PRODUCING METABOLIC LINE PRODUCTS | |
| SG2014010441A (en) | Preparation process of l-methionine | |
| GB201410312D0 (en) | Photobioreactor | |
| GB201107073D0 (en) | Process | |
| ZA201400918B (en) | Pyrrolidine-3-ylacetic acid derivative | |
| IL229126A0 (en) | process | |
| GB2507679B (en) | Nanostructure tracking of products | |
| ZA201309109B (en) | Methods of treating biomass | |
| GB201119962D0 (en) | Process | |
| GB201104469D0 (en) | Control of phagocytosis | |
| ZA201307229B (en) | Prodrugs of d-isoglutamyl-[d/l]- tryprophan | |
| EP2768941A4 (en) | photobioreactor | |
| GB201103092D0 (en) | Process | |
| EP2782902A4 (en) | DERIVATIVES FROM PHENOXYISOBUTTERIC ACID | |
| GB201114798D0 (en) | Method of modifying surfaces |