PL2684955T3 - Sposób stymulowania angiogenezy, waskularyzacji lub naprawy naczyń lub hamowania angiogenezy nowotworowej - Google Patents

Sposób stymulowania angiogenezy, waskularyzacji lub naprawy naczyń lub hamowania angiogenezy nowotworowej

Info

Publication number: PL2684955T3
Authority: PL; Poland
Prior art keywords: angiogenesis; vascularisation; inhibiting tumour; vessel repair; promoting
Prior art date: 2007-10-30

Application number

PL13179144T

Other languages

English (en)

Inventor

Stefanie Dimmeler

Carmen Urbich

Andreas Zeiher

Angelika Bonauer

Original Assignee

T2Cure Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-30

Filing date

2008-10-30

Publication date

2018-05-30

2008-10-30 Application filed by T2Cure Gmbh filed Critical T2Cure Gmbh

2018-05-30 Publication of PL2684955T3 publication Critical patent/PL2684955T3/pl

Links

230000033115 angiogenesis Effects 0.000 title 2
206010028980 Neoplasm Diseases 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
230000001737 promoting effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Plant Pathology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL13179144T 2007-10-30 2008-10-30 Sposób stymulowania angiogenezy, waskularyzacji lub naprawy naczyń lub hamowania angiogenezy nowotworowej PL2684955T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE102007052114A DE102007052114B4 (de)	2007-10-30	2007-10-30	Verfahren zur Modulation der Funktion, des Wachstums oder der Differenzierung einer Zelle
EP13179144.4A EP2684955B1 (de)	2007-10-30	2008-10-30	Verfahren zur Förderung der Angiogenese, Vaskularisierung oder Gefäßreparatur oder zur Hemmung der Tumorangiogenese
EP08844273.6A EP2217704B1 (de)	2007-10-30	2008-10-30	Verfahren zur förderung der angiogenese, vaskularisierung oder gefässreparatur oder zur hemmung der tumorangiogenese

Publications (1)

Publication Number	Publication Date
PL2684955T3 true PL2684955T3 (pl)	2018-05-30

Family

ID=40375407

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL08844273T PL2217704T3 (pl)	2007-10-30	2008-10-30	Sposób stymulowania angiogenezy, waskularyzacji lub naprawy naczyń lub hamowania angiogenezy nowotworowej
PL13179144T PL2684955T3 (pl)	2007-10-30	2008-10-30	Sposób stymulowania angiogenezy, waskularyzacji lub naprawy naczyń lub hamowania angiogenezy nowotworowej

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL08844273T PL2217704T3 (pl)	2007-10-30	2008-10-30	Sposób stymulowania angiogenezy, waskularyzacji lub naprawy naczyń lub hamowania angiogenezy nowotworowej

Country Status (16)

Country	Link
US (4)	US8258113B2 (pl)
EP (3)	EP2217704B1 (pl)
JP (4)	JP5898843B2 (pl)
CA (1)	CA2704290C (pl)
CY (2)	CY1120360T1 (pl)
DE (1)	DE102007052114B4 (pl)
DK (2)	DK2217704T3 (pl)
ES (2)	ES2618203T3 (pl)
HR (2)	HRP20170346T1 (pl)
HU (2)	HUE031559T2 (pl)
LT (2)	LT2684955T (pl)
NO (1)	NO2684955T3 (pl)
PL (2)	PL2217704T3 (pl)
PT (2)	PT2684955T (pl)
SI (2)	SI2684955T1 (pl)
WO (1)	WO2009056116A1 (pl)

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ITRM20030376A1 (it)	2003-07-31	2005-02-01	Univ Roma	Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
US11660317B2 (en)	2004-11-08	2023-05-30	The Johns Hopkins University	Compositions comprising cardiosphere-derived cells for use in cell therapy
ES2911034T3 (es)	2006-08-08	2022-05-17	Univ Bonn Rheinische Friedrich Wilhelms	Estructura y uso de oligonucleótidos 5' fosfato
DE102007052114B4 (de)	2007-10-30	2011-01-05	T2Cure Gmbh	Verfahren zur Modulation der Funktion, des Wachstums oder der Differenzierung einer Zelle
WO2009141146A1 (en)	2008-05-21	2009-11-26	Gunther Hartmann	5' triphosphate oligonucleotide with blunt end and uses thereof
US9249392B2 (en)	2010-04-30	2016-02-02	Cedars-Sinai Medical Center	Methods and compositions for maintaining genomic stability in cultured stem cells
US9845457B2 (en)	2010-04-30	2017-12-19	Cedars-Sinai Medical Center	Maintenance of genomic stability in cultured stem cells
EP2638158A4 (en) *	2010-11-11	2015-07-15	Univ Miami	COMPOSITIONS, CELLS, KITS AND METHODS FOR AUTOLOGOUS STEM CELL THERAPY
EP2508530A1 (en)	2011-03-28	2012-10-10	Rheinische Friedrich-Wilhelms-Universität Bonn	Purification of triphosphorylated oligonucleotides using capture tags
US9884076B2 (en)	2012-06-05	2018-02-06	Capricor, Inc.	Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
CN107236735B (zh)	2012-06-21	2019-11-08	米拉根医疗股份有限公司	包含锁核酸基序的基于寡核苷酸的抑制剂
EP3563859B1 (en)	2012-08-13	2021-10-13	Cedars-Sinai Medical Center	Cardiosphere-derived exosomes for tissue regeneration
EP2712870A1 (en)	2012-09-27	2014-04-02	Rheinische Friedrich-Wilhelms-Universität Bonn	Novel RIG-I ligands and methods for producing them
ES2606636T3 (es) *	2013-01-24	2017-03-24	Pierre Fabre Médicament S.A.S.	Composición que comprende un antagomir encapsulado
DK2970968T3 (en)	2013-03-15	2018-03-05	Miragen Therapeutics Inc	CONNECTED BICYCLIC Nucleosides
US11253549B2 (en)	2014-05-23	2022-02-22	JangoBio, LLC	Methods to rebalance the hypothalamic-pituitary-gonadal axis
US11439668B2 (en)	2014-05-23	2022-09-13	JangoBio, LLC	Methods to differentiate stem cells into hormone-producing cells
EP4494699A3 (en)	2014-10-03	2025-04-30	Cedars-Sinai Medical Center	Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
US20160122762A1 (en) *	2014-10-27	2016-05-05	University Of Iowa Research Foundation	Methods of treating atherosclerosis
EP3247716A4 (en)	2015-01-20	2018-10-17	Miragen Therapeutics, Inc.	Mir-92 inhibitors and uses thereof
WO2017123662A1 (en)	2016-01-11	2017-07-20	Cedars-Sinai Medical Center	Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
WO2017210652A1 (en)	2016-06-03	2017-12-07	Cedars-Sinai Medical Center	Cdc-derived exosomes for treatment of ventricular tachyarrythmias
CN107586784B (zh) *	2016-07-08	2020-08-25	田小利	一种分离的rnasek基因及其在制备抗血管衰老药物中的应用
US11541078B2 (en)	2016-09-20	2023-01-03	Cedars-Sinai Medical Center	Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
JP7336769B2 (ja)	2017-04-19	2023-09-01	シーダーズ―シナイメディカルセンター	骨格筋ジストロフィーを治療する方法及び組成物
WO2019126068A1 (en)	2017-12-20	2019-06-27	Cedars-Sinai Medical Center	Engineered extracellular vesicles for enhanced tissue delivery
EP3749344A4 (en)	2018-02-05	2022-01-26	Cedars-Sinai Medical Center	METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS
EP3760209B1 (en) *	2018-02-28	2023-11-22	National University Corporation Tokyo Medical and Dental University	Ischemic-lesion-site-specific gene therapy

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US7683036B2 (en) *	2003-07-31	2010-03-23	Regulus Therapeutics Inc.	Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
EP2290073A3 (en) *	2004-05-28	2011-08-31	Asuragen, Inc.	Methods and compositions involving microRNA
WO2006133022A2 (en) *	2005-06-03	2006-12-14	The Johns Hopkins University	Compositions and methods for decreasing microrna expression for the treatment of neoplasia
EP2041317A4 (en) *	2006-07-13	2009-10-14	Univ Ohio State Res Found	METHODS AND COMPOSITIONS BASED ON MICRO-RNA FOR THE DIAGNOSIS AND TREATMENT OF COLON CANCER RELATED DISEASES
WO2008014008A2 (en) *	2006-07-28	2008-01-31	The Johns Hopkins University	Compositions and methods for modulating angiogenesis
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CA2693031A1 (en) *	2007-07-18	2009-01-22	The Regents Of The University Colorado	Differential expression of micrornas in nonfailing versus failing human hearts
DE102007052114B4 (de)	2007-10-30	2011-01-05	T2Cure Gmbh	Verfahren zur Modulation der Funktion, des Wachstums oder der Differenzierung einer Zelle

2007
- 2007-10-30 DE DE102007052114A patent/DE102007052114B4/de active Active
2008
- 2008-10-30 US US12/739,876 patent/US8258113B2/en active Active
- 2008-10-30 NO NO13179144A patent/NO2684955T3/no unknown
- 2008-10-30 HR HRP20170346TT patent/HRP20170346T1/hr unknown
- 2008-10-30 EP EP08844273.6A patent/EP2217704B1/de active Active
- 2008-10-30 EP EP13179144.4A patent/EP2684955B1/de active Active
- 2008-10-30 SI SI200831894T patent/SI2684955T1/en unknown
- 2008-10-30 ES ES08844273.6T patent/ES2618203T3/es active Active
- 2008-10-30 LT LTEP13179144.4T patent/LT2684955T/lt unknown
- 2008-10-30 JP JP2010531412A patent/JP5898843B2/ja not_active Expired - Fee Related
- 2008-10-30 DK DK08844273.6T patent/DK2217704T3/en active
- 2008-10-30 WO PCT/DE2008/001759 patent/WO2009056116A1/de not_active Ceased
- 2008-10-30 ES ES13179144.4T patent/ES2651287T3/es active Active
- 2008-10-30 PL PL08844273T patent/PL2217704T3/pl unknown
- 2008-10-30 PT PT131791444T patent/PT2684955T/pt unknown
- 2008-10-30 LT LTEP08844273.6T patent/LT2217704T/lt unknown
- 2008-10-30 SI SI200831774A patent/SI2217704T1/sl unknown
- 2008-10-30 CA CA2704290A patent/CA2704290C/en not_active Expired - Fee Related
- 2008-10-30 DK DK13179144.4T patent/DK2684955T3/en active
- 2008-10-30 HU HUE08844273A patent/HUE031559T2/hu unknown
- 2008-10-30 HU HUE13179144A patent/HUE037494T2/hu unknown
- 2008-10-30 PL PL13179144T patent/PL2684955T3/pl unknown
- 2008-10-30 PT PT88442736T patent/PT2217704T/pt unknown
- 2008-10-30 EP EP13179146.9A patent/EP2684956B1/de active Active
2012
- 2012-08-08 US US13/569,786 patent/US8912158B2/en active Active
2014
- 2014-06-05 JP JP2014116545A patent/JP2014196317A/ja active Pending
- 2014-07-31 US US14/448,119 patent/US9279123B2/en active Active
2016
- 2016-02-10 US US15/040,487 patent/US9862949B2/en active Active
- 2016-06-24 JP JP2016125260A patent/JP2016199565A/ja active Pending
2017
- 2017-02-22 CY CY20171100245T patent/CY1120360T1/el unknown
- 2017-12-04 HR HRP20171874TT patent/HRP20171874T1/hr unknown
- 2017-12-06 CY CY20171101283T patent/CY1120226T1/el unknown
- 2017-12-14 JP JP2017239230A patent/JP2018083817A/ja active Pending

Also Published As

Publication number	Publication date
CA2704290C (en)	2018-05-15
DK2217704T3 (en)	2017-03-13
JP2011500858A (ja)	2011-01-06
CA2704290A1 (en)	2009-05-07
NO2684955T3 (pl)	2018-02-03
PL2217704T3 (pl)	2017-06-30
LT2217704T (lt)	2017-04-10
US20100324118A1 (en)	2010-12-23
JP2016199565A (ja)	2016-12-01
HUE037494T2 (hu)	2018-08-28
LT2684955T (lt)	2017-12-27
DK2684955T3 (en)	2017-12-18
US8258113B2 (en)	2012-09-04
US20120322856A1 (en)	2012-12-20
EP2684955A1 (de)	2014-01-15
JP2014196317A (ja)	2014-10-16
US20160237433A1 (en)	2016-08-18
EP2684955B1 (de)	2017-09-06
JP5898843B2 (ja)	2016-04-06
US8912158B2 (en)	2014-12-16
PT2217704T (pt)	2017-03-15
US9862949B2 (en)	2018-01-09
HUE031559T2 (hu)	2017-07-28
WO2009056116A1 (de)	2009-05-07
HRP20171874T1 (hr)	2018-01-12
CY1120360T1 (el)	2019-07-10
EP2684956B1 (de)	2017-08-23
ES2651287T3 (es)	2018-01-25
EP2217704B1 (de)	2016-12-07
HRP20170346T1 (hr)	2017-04-21
JP2018083817A (ja)	2018-05-31
US9279123B2 (en)	2016-03-08
EP2684956A1 (de)	2014-01-15
CY1120226T1 (el)	2018-12-12
US20150018407A1 (en)	2015-01-15
SI2217704T1 (sl)	2017-05-31
SI2684955T1 (en)	2018-01-31
EP2217704A1 (de)	2010-08-18
ES2618203T3 (es)	2017-06-21
DE102007052114A1 (de)	2009-05-07
DE102007052114B4 (de)	2011-01-05
PT2684955T (pt)	2017-12-13

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