PL2705155T3 - Racjonalne projektowanie składników katalizowanej przez transferazę oligosacharydową glikozylacji przez połączenie z asparaginą - Google Patents

Racjonalne projektowanie składników katalizowanej przez transferazę oligosacharydową glikozylacji przez połączenie z asparaginą

Info

Publication number
PL2705155T3
PL2705155T3 PL12729340.5T PL12729340T PL2705155T3 PL 2705155 T3 PL2705155 T3 PL 2705155T3 PL 12729340 T PL12729340 T PL 12729340T PL 2705155 T3 PL2705155 T3 PL 2705155T3
Authority
PL
Poland
Prior art keywords
saccharyltransferase
oligo
components
linked glycosylation
rational design
Prior art date
Application number
PL12729340.5T
Other languages
English (en)
Inventor
Markus Aebi
Kaspar Locher
Christian Lizak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2705155T3 publication Critical patent/PL2705155T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30Drug targeting using structural data; Docking or binding prediction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL12729340.5T 2011-05-04 2012-05-03 Racjonalne projektowanie składników katalizowanej przez transferazę oligosacharydową glikozylacji przez połączenie z asparaginą PL2705155T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11003648 2011-05-04

Publications (1)

Publication Number Publication Date
PL2705155T3 true PL2705155T3 (pl) 2016-10-31

Family

ID=46354132

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12729340.5T PL2705155T3 (pl) 2011-05-04 2012-05-03 Racjonalne projektowanie składników katalizowanej przez transferazę oligosacharydową glikozylacji przez połączenie z asparaginą

Country Status (12)

Country Link
US (1) US9881124B2 (pl)
EP (1) EP2705155B1 (pl)
JP (1) JP2014516519A (pl)
KR (1) KR20140003658A (pl)
CN (1) CN103620053B (pl)
AU (1) AU2012251886B2 (pl)
CA (1) CA2833457C (pl)
ES (1) ES2587302T3 (pl)
IL (1) IL229133A0 (pl)
PL (1) PL2705155T3 (pl)
SG (1) SG194456A1 (pl)
WO (1) WO2012150034A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201700446XA (en) 2014-07-21 2017-02-27 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
WO2016023018A2 (en) * 2014-08-08 2016-02-11 Glycobia, Inc. Engineered oligosaccharyltransferases
HRP20240776T1 (hr) 2019-08-09 2024-09-13 Glaxosmithkline Biologicals Sa Mutirani enzimi pglb oligosahariltransferaze

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006235490A1 (en) 2005-04-12 2006-10-19 Romark Laboratories, L.C. Methods for treating diseases through the function of molecular chaperones such as protein disulfide isomerases, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents

Also Published As

Publication number Publication date
ES2587302T3 (es) 2016-10-21
KR20140003658A (ko) 2014-01-09
CA2833457A1 (en) 2012-11-08
SG194456A1 (en) 2013-12-30
EP2705155A1 (en) 2014-03-12
CA2833457C (en) 2018-01-30
US9881124B2 (en) 2018-01-30
CN103620053B (zh) 2016-04-06
US20140100836A1 (en) 2014-04-10
EP2705155B1 (en) 2016-04-27
AU2012251886A1 (en) 2013-10-24
WO2012150034A1 (en) 2012-11-08
CN103620053A (zh) 2014-03-05
AU2012251886B2 (en) 2016-01-28
IL229133A0 (en) 2013-12-31
JP2014516519A (ja) 2014-07-17

Similar Documents

Publication Publication Date Title
PL2281747T3 (pl) Statek powietrzny
GB201213905D0 (en) Component assembly
GB2485334B (en) Structure
TWM401068U (en) Screw
GB2494018B (en) Electrical functional plaster
EP2565986A4 (en) FLAT STRUCTURED EBG
GB201006445D0 (en) Achomedis screw assembly
GB0917059D0 (en) No-back arrangement
EP2616548A4 (en) NANODEAGGREGATED CELLULOSE
EP2657244A4 (en) glycoside
GB201211984D0 (en) Rigless intervention
EP2719552A4 (en) MOUNTING STRUCTURE
GB2476838B (en) Screw
IL229133A0 (en) Intelligent design of oligo-saccharyltransferase-catalyzed asparagine-linked glycosylation components
HUP1100726A2 (en) Component
EP2591985A4 (en) PANEL ASSEMBLY STRUCTURE
GB2481439B (en) Connection arrangement
EP2535541A4 (en) AIRCRAFT
PL389502A1 (pl) Statek powietrzny
GB0900818D0 (en) Aircraft wing-box
GB201013636D0 (en) Glycosylation process
GB201006473D0 (en) Anfibian aircraft
AU325319S (en) Aircraft
PL389964A1 (pl) Statek powietrzny
TWM391251U (en) Ceramic PCB structure