PL2707363T3 - Sposób wytwarzania [(3aS,4R,6S,6aR)-6-hydroksy-2,2- dimetylotetrahydro-3aH-cyklopenta[d][1,3]dioksol]-4-ilo]karbaminianu benzylu i związki pośrednie w tym sposobie - Google Patents

Sposób wytwarzania [(3aS,4R,6S,6aR)-6-hydroksy-2,2- dimetylotetrahydro-3aH-cyklopenta[d][1,3]dioksol]-4-ilo]karbaminianu benzylu i związki pośrednie w tym sposobie

Info

Publication number: PL2707363T3
Authority: PL; Poland
Prior art keywords: dimethyltetrahydro; dioxol; cyclopenta; carbamate; intermediates
Prior art date: 2011-05-13

Application number

PL12785416T

Other languages

English (en)

Inventor

Tibor Musil

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-13

Filing date

2012-05-11

Publication date

2016-02-29

2012-05-11 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2016-02-29 Publication of PL2707363T3 publication Critical patent/PL2707363T3/pl

Links

KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL12785416T 2011-05-13 2012-05-11 Sposób wytwarzania [(3aS,4R,6S,6aR)-6-hydroksy-2,2- dimetylotetrahydro-3aH-cyklopenta[d][1,3]dioksol]-4-ilo]karbaminianu benzylu i związki pośrednie w tym sposobie PL2707363T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201161485691P	2011-05-13	2011-05-13
US201161540084P	2011-09-28	2011-09-28
PCT/SE2012/050498 WO2012158099A1 (en)	2011-05-13	2012-05-11	A process for the preparation of benzyl [(3as,4r,6s,6ar)-6-hydroxy-2,2- dimethyltetrahydro-3ah-cyclopenta[d][1,3]dioxol]-4-yl]carbamate and intermediates in the process
EP12785416.4A EP2707363B1 (en)	2011-05-13	2012-05-11	A process for the preparation of benzyl [(3as,4r,6s,6ar)-6-hydroxy-2,2- dimethyltetrahydro-3ah-cyclopenta[d][1,3]dioxol]-4-yl]carbamate and intermediates in the process

Publications (1)

Publication Number	Publication Date
PL2707363T3 true PL2707363T3 (pl)	2016-02-29

Family

ID=47177189

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL12785416T PL2707363T3 (pl)	2011-05-13	2012-05-11	Sposób wytwarzania [(3aS,4R,6S,6aR)-6-hydroksy-2,2- dimetylotetrahydro-3aH-cyklopenta[d][1,3]dioksol]-4-ilo]karbaminianu benzylu i związki pośrednie w tym sposobie

Country Status (26)

Country	Link
US (1)	US9079873B2 (pl)
EP (1)	EP2707363B1 (pl)
JP (1)	JP6023795B2 (pl)
KR (1)	KR20140028070A (pl)
CN (1)	CN103534245B (pl)
AR (1)	AR086351A1 (pl)
AU (1)	AU2012256439B2 (pl)
BR (1)	BR112013028936B1 (pl)
CA (1)	CA2834935A1 (pl)
CY (1)	CY1117592T1 (pl)
DK (1)	DK2707363T3 (pl)
ES (1)	ES2556833T3 (pl)
HR (1)	HRP20151328T1 (pl)
HU (1)	HUE027145T2 (pl)
IL (1)	IL229075A (pl)
MX (1)	MX2013013221A (pl)
MY (1)	MY163203A (pl)
PL (1)	PL2707363T3 (pl)
PT (1)	PT2707363E (pl)
RS (1)	RS54443B1 (pl)
RU (1)	RU2588673C2 (pl)
SG (1)	SG194585A1 (pl)
SI (1)	SI2707363T1 (pl)
SM (1)	SMT201500309B (pl)
TW (1)	TWI537256B (pl)
WO (1)	WO2012158099A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN104513221A (zh) *	2013-09-26	2015-04-15	上海科胜药物研发有限公司	一种制备光学活性的替卡格雷中间体的方法
CN108484566A (zh) *	2018-02-26	2018-09-04	苏州楚凯药业有限公司	一种替格瑞洛关键中间体的制备方法
CN117551071A (zh) *	2023-10-13	2024-02-13	重庆普佑生物医药有限公司	替卡格雷中间体及其制备方法和应用该中间体的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9702772D0 (sv) *	1997-07-22	1997-07-22	Astra Pharma Prod	Novel compounds
US6316671B1 (en) *	1997-11-28	2001-11-13	Universite De Rouen	Method for splitting 1-amino-alkan-2-ol compounds
TWI229674B (en) *	1998-12-04	2005-03-21	Astra Pharma Prod	Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
JP4406483B2 (ja) *	1999-11-17	2010-01-27	株式会社デ・ウエスタン・セラピテクス研究所	光学活性２−アミノシクロヘキサノール誘導体の製造方法
GB0013488D0 (en) *	2000-06-02	2000-07-26	Astrazeneca Ab	Chemical compound
JP2005104874A (ja) *	2003-09-29	2005-04-21	Yamakawa Yakuhin Kogyo Kk	光学活性なα−アミノ−ε−カプロラクタムまたはその塩の製造方法および製造の中間体
WO2007055180A1 (ja) *	2005-11-09	2007-05-18	Toray Fine Chemicals Co., Ltd.	光学活性トランス－２－アミノシクロヘキサノールおよびその誘導体の製造方法
JP2009023978A (ja) *	2007-07-23	2009-02-05	Kaneka Corp	トランス−２−ベンジロキシシクロヘキシルアミンの製造法
TWI496776B (zh)	2007-11-15	2015-08-21	Astrazeneca Ab	製備(3aR,4S,6R,6aS)-6-胺基-2,2-二甲基四氫-3aH-環戊并[d][1,3]二氧雜環戊烯-4-醇之純非對映異構性之二苯甲醯-L-酒石酸鹽之方法
RU2400478C1 (ru) *	2009-02-24	2010-09-27	Учреждение Российской академии наук Институт органической химии Уфимского научного центра РАН	Способ получения (4s,5s)-4,5-о-изопропилиденциклопент-2-ен-1-она
EP2459564B1 (en) *	2009-07-27	2016-09-07	Auspex Pharmaceuticals, Inc.	Cyclopropyl modulators of p2y12 receptor

2012
- 2012-05-11 PL PL12785416T patent/PL2707363T3/pl unknown
- 2012-05-11 CA CA2834935A patent/CA2834935A1/en not_active Abandoned
- 2012-05-11 AU AU2012256439A patent/AU2012256439B2/en active Active
- 2012-05-11 MX MX2013013221A patent/MX2013013221A/es unknown
- 2012-05-11 HU HUE12785416A patent/HUE027145T2/en unknown
- 2012-05-11 DK DK12785416.4T patent/DK2707363T3/en active
- 2012-05-11 SI SI201230397T patent/SI2707363T1/sl unknown
- 2012-05-11 TW TW101116976A patent/TWI537256B/zh active
- 2012-05-11 ES ES12785416.4T patent/ES2556833T3/es active Active
- 2012-05-11 RU RU2013150325/04A patent/RU2588673C2/ru active
- 2012-05-11 SG SG2013078621A patent/SG194585A1/en unknown
- 2012-05-11 RS RS20150821A patent/RS54443B1/sr unknown
- 2012-05-11 BR BR112013028936-8A patent/BR112013028936B1/pt active IP Right Grant
- 2012-05-11 KR KR1020137032916A patent/KR20140028070A/ko not_active Withdrawn
- 2012-05-11 PT PT127854164T patent/PT2707363E/pt unknown
- 2012-05-11 AR ARP120101663A patent/AR086351A1/es active IP Right Grant
- 2012-05-11 EP EP12785416.4A patent/EP2707363B1/en active Active
- 2012-05-11 WO PCT/SE2012/050498 patent/WO2012158099A1/en not_active Ceased
- 2012-05-11 CN CN201280023753.3A patent/CN103534245B/zh active Active
- 2012-05-11 JP JP2014510277A patent/JP6023795B2/ja active Active
- 2012-05-11 HR HRP20151328TT patent/HRP20151328T1/hr unknown
- 2012-05-11 MY MYPI2013702133A patent/MY163203A/en unknown
- 2012-05-11 US US14/117,077 patent/US9079873B2/en active Active
2013
- 2013-10-24 IL IL229075A patent/IL229075A/en active IP Right Grant
2015
- 2015-12-09 SM SM201500309T patent/SMT201500309B/it unknown
- 2015-12-15 CY CY20151101145T patent/CY1117592T1/el unknown

Also Published As

Publication number	Publication date
JP6023795B2 (ja)	2016-11-09
EP2707363B1 (en)	2015-10-21
WO2012158099A1 (en)	2012-11-22
HRP20151328T1 (hr)	2016-01-01
BR112013028936B1 (pt)	2021-10-19
TW201249820A (en)	2012-12-16
AU2012256439A1 (en)	2013-05-02
CN103534245A (zh)	2014-01-22
HUE027145T2 (en)	2016-08-29
DK2707363T3 (en)	2015-12-21
JP2014524885A (ja)	2014-09-25
CY1117592T1 (el)	2017-04-26
MX2013013221A (es)	2013-12-02
TWI537256B (zh)	2016-06-11
RU2013150325A (ru)	2015-06-20
HK1195307A1 (zh)	2014-11-07
CN103534245B (zh)	2015-08-19
BR112013028936A2 (pt)	2016-08-09
EP2707363A1 (en)	2014-03-19
PT2707363E (pt)	2016-01-07
AR086351A1 (es)	2013-12-04
RS54443B1 (sr)	2016-06-30
IL229075A0 (en)	2013-12-31
KR20140028070A (ko)	2014-03-07
US9079873B2 (en)	2015-07-14
EP2707363A4 (en)	2014-11-12
AU2012256439B2 (en)	2015-10-22
IL229075A (en)	2016-10-31
MY163203A (en)	2017-08-15
CA2834935A1 (en)	2012-11-22
ES2556833T3 (es)	2016-01-20
RU2588673C2 (ru)	2016-07-10
SI2707363T1 (sl)	2016-01-29
SG194585A1 (en)	2013-12-30
SMT201500309B (it)	2016-01-08
US20140135509A1 (en)	2014-05-15

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