PL2714676T3 - Sposób wytwarzania formy polimorficznej I etorykoksybu - Google Patents
Sposób wytwarzania formy polimorficznej I etorykoksybuInfo
- Publication number
- PL2714676T3 PL2714676T3 PL12723214T PL12723214T PL2714676T3 PL 2714676 T3 PL2714676 T3 PL 2714676T3 PL 12723214 T PL12723214 T PL 12723214T PL 12723214 T PL12723214 T PL 12723214T PL 2714676 T3 PL2714676 T3 PL 2714676T3
- Authority
- PL
- Poland
- Prior art keywords
- etoricoxib
- preparation
- polymorphic form
- polymorphic
- Prior art date
Links
- MNJVRJDLRVPLFE-UHFFFAOYSA-N etoricoxib Chemical compound C1=NC(C)=CC=C1C1=NC=C(Cl)C=C1C1=CC=C(S(C)(=O)=O)C=C1 MNJVRJDLRVPLFE-UHFFFAOYSA-N 0.000 title 1
- 229960004945 etoricoxib Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI201100190 | 2011-05-27 | ||
| PCT/EP2012/059852 WO2012163839A1 (en) | 2011-05-27 | 2012-05-25 | A process for the preparation of polymorphic form i of etoricoxib |
| EP12723214.8A EP2714676B1 (en) | 2011-05-27 | 2012-05-25 | A process for the preparation of polymorphic form i of etoricoxib |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2714676T3 true PL2714676T3 (pl) | 2019-10-31 |
Family
ID=46148892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12723214T PL2714676T3 (pl) | 2011-05-27 | 2012-05-25 | Sposób wytwarzania formy polimorficznej I etorykoksybu |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2714676B1 (pl) |
| EA (1) | EA023286B1 (pl) |
| PL (1) | PL2714676T3 (pl) |
| SI (1) | SI2714676T1 (pl) |
| WO (1) | WO2012163839A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2831045A2 (en) * | 2012-03-30 | 2015-02-04 | Mylan Laboratories, Limited | An improved process for the preparation of etoricoxib |
| EP2888231B1 (en) * | 2012-08-27 | 2019-01-09 | Glenmark Pharmaceuticals Limited | Process for preparation of crystalline etoricoxib |
| WO2014033526A1 (en) * | 2012-08-27 | 2014-03-06 | Cadila Healthcare Limited | Pharmaceutical compositions of etoricoxib |
| WO2016015776A1 (en) * | 2014-07-31 | 2016-02-04 | Krka, D.D., Novo Mesto | Pharmaceutical composition of etoricoxib |
| CN105250231B (zh) * | 2015-11-02 | 2020-05-12 | 北京泰德制药股份有限公司 | 一种含有依托考昔的药物组合物及其制备方法 |
| CN111410629A (zh) * | 2020-03-31 | 2020-07-14 | 天津大学 | 依托考昔溶剂化物及其制备方法 |
| CN112321493A (zh) * | 2020-10-28 | 2021-02-05 | 四川尚锐生物医药有限公司 | 一种依托考昔的纯化方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EE03680B1 (et) | 1996-07-18 | 2002-04-15 | Merck Frosst Canada & Co. / Merck Frosst Canada &Cie. | Asendatud püridiinid, nende kasutamine ja farmatseutilised kompositsioonid |
| US5861419A (en) | 1996-07-18 | 1999-01-19 | Merck Frosst Canad, Inc. | Substituted pyridines as selective cyclooxygenase-2 inhibitors |
| EA002975B1 (ru) | 1998-04-24 | 2002-12-26 | Мерк Энд Ко., Инк. | Способ синтеза ингибиторов циклооксигеназы-2 |
| ES2259295T3 (es) | 1999-11-29 | 2006-10-01 | Merck Frosst Canada Inc. | Formas polimorficas, amorfas e hidratadas de 5-cloro-3-(4-metanosulfonilfenil)-6'-metil-(2,3')bipiridinilo. |
| PH12001001175B1 (en) | 2000-05-26 | 2006-08-10 | Merck Sharp & Dohme | 5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl- (2,3')bipyridinyl in pure crystalline form and process for synthesis |
| US6521642B2 (en) * | 2000-05-26 | 2003-02-18 | Merck & Co., Inc. | 5-chloro-3-(4-methanesulfonylphenyl)-6′-methyl-[2,3′]bipyridinyl in pure crystalline form and process for synthesis |
| WO2005085199A1 (en) | 2004-01-14 | 2005-09-15 | Cadila Healthcare Limited | Novel polymorphs of etoricoxib |
| ES2496465T3 (es) * | 2009-02-27 | 2014-09-19 | Cadila Healthcare Limited | Un procedimiento para la preparación de Etoricoxib |
-
2012
- 2012-05-25 SI SI201231601T patent/SI2714676T1/sl unknown
- 2012-05-25 EP EP12723214.8A patent/EP2714676B1/en not_active Not-in-force
- 2012-05-25 PL PL12723214T patent/PL2714676T3/pl unknown
- 2012-05-25 EA EA201391721A patent/EA023286B1/ru not_active IP Right Cessation
- 2012-05-25 WO PCT/EP2012/059852 patent/WO2012163839A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EA201391721A1 (ru) | 2014-03-31 |
| WO2012163839A1 (en) | 2012-12-06 |
| EP2714676A1 (en) | 2014-04-09 |
| EP2714676B1 (en) | 2019-04-24 |
| SI2714676T1 (sl) | 2019-06-28 |
| EA023286B1 (ru) | 2016-05-31 |
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