PL2723727T3 - Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftolu - Google Patents

Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftolu

Info

Publication number
PL2723727T3
PL2723727T3 PL12803844T PL12803844T PL2723727T3 PL 2723727 T3 PL2723727 T3 PL 2723727T3 PL 12803844 T PL12803844 T PL 12803844T PL 12803844 T PL12803844 T PL 12803844T PL 2723727 T3 PL2723727 T3 PL 2723727T3
Authority
PL
Poland
Prior art keywords
tetrahydronaphthol
substituted amino
nitrogen substituted
preparing nitrogen
industrially preparing
Prior art date
Application number
PL12803844T
Other languages
English (en)
Inventor
Mina Yang
Qingguo Meng
Tao Wang
Qilin Wang
Jun Li
Zheng Ruan
Original Assignee
Shan Dong Luye Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shan Dong Luye Pharmaceutical Co., Ltd. filed Critical Shan Dong Luye Pharmaceutical Co., Ltd.
Publication of PL2723727T3 publication Critical patent/PL2723727T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL12803844T 2011-06-27 2012-06-21 Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftolu PL2723727T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110179616 2011-06-27
EP12803844.5A EP2723727B1 (en) 2011-06-27 2012-06-21 Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol

Publications (1)

Publication Number Publication Date
PL2723727T3 true PL2723727T3 (pl) 2017-08-31

Family

ID=47423417

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12803844T PL2723727T3 (pl) 2011-06-27 2012-06-21 Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftolu

Country Status (12)

Country Link
US (1) US8809590B2 (pl)
EP (1) EP2723727B1 (pl)
JP (1) JP5643467B2 (pl)
KR (1) KR101478597B1 (pl)
CN (1) CN103649071B (pl)
AU (1) AU2012276179B2 (pl)
BR (1) BR112013033559A2 (pl)
CA (1) CA2839366C (pl)
ES (1) ES2626024T3 (pl)
PL (1) PL2723727T3 (pl)
RU (1) RU2558145C1 (pl)
WO (1) WO2013000273A1 (pl)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
EP0026848B1 (de) * 1979-09-14 1983-05-04 Sandoz Ag Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten
JPS60258146A (ja) * 1984-06-01 1985-12-20 ウイットバイ リサーチ インコーポレイテッド 置換2−アミノテトラリン類及び合成方法
US5382596A (en) * 1993-08-05 1995-01-17 Whitby Research, Inc. Substituted 2-aminotetralins
HK1052514A1 (zh) * 1999-11-23 2003-09-19 阿德里斯制药公司 制备氮取代的氨基1,2,3,4-四氢化萘的改进方法
JP5595404B2 (ja) * 2008-10-13 2014-09-24 インテルキム、ソシエダッド アノニマ 光学活性(s)−(−)−2−(n−プロピルアミノ)−5−メトキシテトラリン及び(s)−(−)−2−(n−プロピルアミノ)−5−ヒドロキシテトラリン化合物の調製の方法
KR101774598B1 (ko) * 2008-12-09 2017-09-04 인터퀴임, 에스.에이. (6s)­(­)­5,6,7,8­테트라하이드로-6-[프로필­(2­티에닐)에틸]아미노­1­나프톨(로티고틴)의 제조를 위한 공정
CN102010400B (zh) * 2009-09-07 2015-02-04 药源药物化学(上海)有限公司 S-5-取代-n-2'-(噻吩-2-基-)乙基-1,2,3,4-四氢萘-2-胺或其手性酸盐和用于制备罗替戈汀

Also Published As

Publication number Publication date
CN103649071A (zh) 2014-03-19
EP2723727A1 (en) 2014-04-30
US8809590B2 (en) 2014-08-19
BR112013033559A2 (pt) 2016-08-16
AU2012276179A1 (en) 2014-01-16
KR101478597B1 (ko) 2015-01-02
AU2012276179B2 (en) 2015-09-24
HK1189887A1 (en) 2014-06-20
CA2839366C (en) 2015-01-20
JP5643467B2 (ja) 2014-12-17
ES2626024T3 (es) 2017-07-21
KR20140027492A (ko) 2014-03-06
EP2723727A4 (en) 2015-01-07
US20140121380A1 (en) 2014-05-01
WO2013000273A1 (en) 2013-01-03
CA2839366A1 (en) 2013-01-03
RU2558145C1 (ru) 2015-07-27
EP2723727B1 (en) 2017-03-01
JP2014523428A (ja) 2014-09-11
CN103649071B (zh) 2014-07-30

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