PL2723727T3 - Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftolu - Google Patents
Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftoluInfo
- Publication number
- PL2723727T3 PL2723727T3 PL12803844T PL12803844T PL2723727T3 PL 2723727 T3 PL2723727 T3 PL 2723727T3 PL 12803844 T PL12803844 T PL 12803844T PL 12803844 T PL12803844 T PL 12803844T PL 2723727 T3 PL2723727 T3 PL 2723727T3
- Authority
- PL
- Poland
- Prior art keywords
- tetrahydronaphthol
- substituted amino
- nitrogen substituted
- preparing nitrogen
- industrially preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110179616 | 2011-06-27 | ||
| EP12803844.5A EP2723727B1 (en) | 2011-06-27 | 2012-06-21 | Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2723727T3 true PL2723727T3 (pl) | 2017-08-31 |
Family
ID=47423417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12803844T PL2723727T3 (pl) | 2011-06-27 | 2012-06-21 | Sposób do przemysłowego wytwarzania podstawionego na azocie amino-5,6,7,8-tetrahydronaftolu |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8809590B2 (pl) |
| EP (1) | EP2723727B1 (pl) |
| JP (1) | JP5643467B2 (pl) |
| KR (1) | KR101478597B1 (pl) |
| CN (1) | CN103649071B (pl) |
| AU (1) | AU2012276179B2 (pl) |
| BR (1) | BR112013033559A2 (pl) |
| CA (1) | CA2839366C (pl) |
| ES (1) | ES2626024T3 (pl) |
| PL (1) | PL2723727T3 (pl) |
| RU (1) | RU2558145C1 (pl) |
| WO (1) | WO2013000273A1 (pl) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2752659A1 (de) * | 1976-12-07 | 1978-06-08 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
| EP0026848B1 (de) * | 1979-09-14 | 1983-05-04 | Sandoz Ag | Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten |
| JPS60258146A (ja) * | 1984-06-01 | 1985-12-20 | ウイットバイ リサーチ インコーポレイテッド | 置換2−アミノテトラリン類及び合成方法 |
| US5382596A (en) * | 1993-08-05 | 1995-01-17 | Whitby Research, Inc. | Substituted 2-aminotetralins |
| HK1052514A1 (zh) * | 1999-11-23 | 2003-09-19 | 阿德里斯制药公司 | 制备氮取代的氨基1,2,3,4-四氢化萘的改进方法 |
| JP5595404B2 (ja) * | 2008-10-13 | 2014-09-24 | インテルキム、ソシエダッド アノニマ | 光学活性(s)−(−)−2−(n−プロピルアミノ)−5−メトキシテトラリン及び(s)−(−)−2−(n−プロピルアミノ)−5−ヒドロキシテトラリン化合物の調製の方法 |
| KR101774598B1 (ko) * | 2008-12-09 | 2017-09-04 | 인터퀴임, 에스.에이. | (6s)()5,6,7,8테트라하이드로-6-[프로필(2티에닐)에틸]아미노1나프톨(로티고틴)의 제조를 위한 공정 |
| CN102010400B (zh) * | 2009-09-07 | 2015-02-04 | 药源药物化学(上海)有限公司 | S-5-取代-n-2'-(噻吩-2-基-)乙基-1,2,3,4-四氢萘-2-胺或其手性酸盐和用于制备罗替戈汀 |
-
2012
- 2012-06-21 WO PCT/CN2012/000863 patent/WO2013000273A1/en not_active Ceased
- 2012-06-21 AU AU2012276179A patent/AU2012276179B2/en not_active Ceased
- 2012-06-21 CN CN201280031707.8A patent/CN103649071B/zh not_active Expired - Fee Related
- 2012-06-21 EP EP12803844.5A patent/EP2723727B1/en not_active Not-in-force
- 2012-06-21 BR BR112013033559A patent/BR112013033559A2/pt active Search and Examination
- 2012-06-21 KR KR1020147001631A patent/KR101478597B1/ko not_active Expired - Fee Related
- 2012-06-21 PL PL12803844T patent/PL2723727T3/pl unknown
- 2012-06-21 ES ES12803844.5T patent/ES2626024T3/es active Active
- 2012-06-21 US US14/128,131 patent/US8809590B2/en not_active Expired - Fee Related
- 2012-06-21 JP JP2014517396A patent/JP5643467B2/ja not_active Expired - Fee Related
- 2012-06-21 CA CA2839366A patent/CA2839366C/en not_active Expired - Fee Related
- 2012-06-21 RU RU2014102378/04A patent/RU2558145C1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103649071A (zh) | 2014-03-19 |
| EP2723727A1 (en) | 2014-04-30 |
| US8809590B2 (en) | 2014-08-19 |
| BR112013033559A2 (pt) | 2016-08-16 |
| AU2012276179A1 (en) | 2014-01-16 |
| KR101478597B1 (ko) | 2015-01-02 |
| AU2012276179B2 (en) | 2015-09-24 |
| HK1189887A1 (en) | 2014-06-20 |
| CA2839366C (en) | 2015-01-20 |
| JP5643467B2 (ja) | 2014-12-17 |
| ES2626024T3 (es) | 2017-07-21 |
| KR20140027492A (ko) | 2014-03-06 |
| EP2723727A4 (en) | 2015-01-07 |
| US20140121380A1 (en) | 2014-05-01 |
| WO2013000273A1 (en) | 2013-01-03 |
| CA2839366A1 (en) | 2013-01-03 |
| RU2558145C1 (ru) | 2015-07-27 |
| EP2723727B1 (en) | 2017-03-01 |
| JP2014523428A (ja) | 2014-09-11 |
| CN103649071B (zh) | 2014-07-30 |
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