PL2736888T3 - Pochodne kwasu 3-heteroaroiloamino-propionowego i ich zastosowanie jako środków farmaceutycznych - Google Patents
Pochodne kwasu 3-heteroaroiloamino-propionowego i ich zastosowanie jako środków farmaceutycznychInfo
- Publication number
- PL2736888T3 PL2736888T3 PL12738473T PL12738473T PL2736888T3 PL 2736888 T3 PL2736888 T3 PL 2736888T3 PL 12738473 T PL12738473 T PL 12738473T PL 12738473 T PL12738473 T PL 12738473T PL 2736888 T3 PL2736888 T3 PL 2736888T3
- Authority
- PL
- Poland
- Prior art keywords
- heteroaroylamino
- pharmaceuticals
- propionic acid
- acid derivatives
- derivatives
- Prior art date
Links
- 229940111131 antiinflammatory and antirheumatic product propionic acid derivative Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11305971 | 2011-07-26 | ||
| EP12738473.3A EP2736888B1 (en) | 2011-07-26 | 2012-07-25 | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals |
| PCT/EP2012/064628 WO2013014204A2 (en) | 2011-07-26 | 2012-07-25 | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2736888T3 true PL2736888T3 (pl) | 2016-04-29 |
Family
ID=46579041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12738473T PL2736888T3 (pl) | 2011-07-26 | 2012-07-25 | Pochodne kwasu 3-heteroaroiloamino-propionowego i ich zastosowanie jako środków farmaceutycznych |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9353068B2 (pl) |
| EP (2) | EP3037417B1 (pl) |
| JP (2) | JP6021910B2 (pl) |
| KR (1) | KR20140049019A (pl) |
| CN (2) | CN105646362B (pl) |
| AU (2) | AU2012288842A1 (pl) |
| BR (1) | BR112014001518A2 (pl) |
| CA (1) | CA2841905A1 (pl) |
| CY (1) | CY1117397T1 (pl) |
| DK (1) | DK2736888T3 (pl) |
| ES (1) | ES2560381T3 (pl) |
| HK (1) | HK1225714A1 (pl) |
| HR (1) | HRP20160047T1 (pl) |
| HU (1) | HUE028418T2 (pl) |
| IL (2) | IL230126A (pl) |
| MX (1) | MX337173B (pl) |
| MY (1) | MY169319A (pl) |
| PL (1) | PL2736888T3 (pl) |
| PT (1) | PT2736888E (pl) |
| RU (1) | RU2014107000A (pl) |
| SI (1) | SI2736888T1 (pl) |
| WO (1) | WO2013014204A2 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY162786A (en) * | 2011-07-26 | 2017-07-14 | Sanofi Sa | Substituted 3-thiazoloamino-propionic acid derivatives and their use as pharmaceuticals |
| WO2013014204A2 (en) | 2011-07-26 | 2013-01-31 | Sanofi | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals |
| CN107007597A (zh) | 2012-05-31 | 2017-08-04 | 菲尼克斯药品股份公司 | 作为孤儿核受体RORγ调节物的经甲酰胺或磺酰胺取代的噻唑及相关衍生物的制药用途 |
| JO3215B1 (ar) | 2012-08-09 | 2018-03-08 | Phenex Pharmaceuticals Ag | حلقات غير متجانسة بها 5 ذرات تحتوي على النيتروجين بها استبدال بكربوكساميد أو سلفوناميد كمعدلات لمستقبل نووي غير محمي RORy |
| WO2014053533A1 (en) | 2012-10-05 | 2014-04-10 | Sanofi | Use of substituted 3-heteroaroylamino-propionic acid derivatives as pharmaceuticals for prevention/treatment of atrial fibrillation |
| WO2014154727A1 (en) * | 2013-03-28 | 2014-10-02 | Sanofi | Biaryl-propionic acid derivatives and their use as pharmaceuticals |
| JP6359634B2 (ja) | 2013-03-28 | 2018-07-18 | サノフイ | ビアリール−プロピオン酸誘導体および医薬品としてのその使用 |
| WO2015188073A1 (en) * | 2014-06-06 | 2015-12-10 | Research Triangle Institute | Apelin receptor (apj) agonists and uses thereof |
| AU2016366310C1 (en) | 2015-12-09 | 2021-09-09 | Research Triangle Institute | Improved apelin receptor (APJ) agonists and uses thereof |
| ES3032633T3 (en) * | 2016-10-12 | 2025-07-22 | Res Triangle Inst | Heterocyclic apelin receptor (apj) agonists and uses thereof |
| KR20220054391A (ko) | 2019-08-29 | 2022-05-02 | 리서치 트라이앵글 인스티튜트 | 아펠린 수용체 작용제에 대한 방법 및 용도 |
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| US6080767A (en) * | 1996-01-02 | 2000-06-27 | Aventis Pharmaceuticals Products Inc. | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides |
| AR011515A1 (es) * | 1996-12-25 | 2000-08-30 | Agrogene Ltd | Derivado del acido aminobutirico para la proteccion de plantas de enfermedades fungosas y un metodo para proteger un cultivo contra enfermedadesfungosas por ejemplo tomates y papas contra el tizon tardio o temprano, cereales contra el mildiu polvoroso, y pepino, vides, melones contra el mildiu |
| DK1027328T3 (da) * | 1997-10-31 | 2006-11-13 | Aventis Pharma Ltd | Substituerede anilider |
| US6468977B1 (en) * | 1998-03-02 | 2002-10-22 | Apotex Inc. | Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes |
| AU759310B2 (en) * | 1998-08-20 | 2003-04-10 | Agouron Pharmaceuticals, Inc. | Non-peptide GnRH agents, methods and intermediates for their preparation |
| DE19858191A1 (de) * | 1998-12-17 | 2000-06-21 | Aventis Cropscience Gmbh | 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclyl-pyrimidine und ihre Verwendung als Repellentien |
| US6462076B2 (en) | 2000-06-14 | 2002-10-08 | Hoffmann-La Roche Inc. | Beta-amino acid nitrile derivatives as cathepsin K inhibitors |
| JP2002326980A (ja) * | 2001-04-27 | 2002-11-15 | Nippon Nohyaku Co Ltd | ジアミド誘導体及び農園芸用薬剤並びにその使用方法 |
| PL370766A1 (pl) * | 2001-12-04 | 2005-05-30 | F.Hoffmann-La Roche Ag | Podstawione 2-aminocykloalkanokarboksyamidy i ichzastosowanie jako inhibitorów proteaz cysteinowych |
| US20040072802A1 (en) | 2002-10-09 | 2004-04-15 | Jingwu Duan | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha |
| AU2003292218A1 (en) | 2002-12-23 | 2004-07-14 | Sanofi-Aventis Deutschland Gmbh | PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS |
| US20060178433A1 (en) | 2003-03-17 | 2006-08-10 | Yasuhito Yamamoto | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto |
| EP1493740A1 (fr) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés de 5-fluoro-thiophene, leur procédé de preparation, les compositions pharmaceutiques les contenant et leur utilisation comme inhibiteurs de métalloprotéinases |
| EP1493739A1 (fr) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
| US7115646B2 (en) * | 2003-10-08 | 2006-10-03 | Bristol Myers Squibb, Co. | Cyclic diamines and derivatives as factor Xa inhibitors |
| JP2005145839A (ja) | 2003-11-12 | 2005-06-09 | Japan Science & Technology Agency | 新規なカテプシンa阻害剤 |
| TW200526641A (en) * | 2003-12-26 | 2005-08-16 | Daiichi Seiyaku Co | Amidopyrazole derivatives |
| JP5123668B2 (ja) | 2005-01-10 | 2013-01-23 | エグゼリクシス, インコーポレイテッド | 医薬品としての複素環カルボキサミド化合物 |
| AU2007226673A1 (en) * | 2006-03-10 | 2007-09-20 | Jenrin Discovery | Cannabinoid receptor antagonists/inverse agonists useful for treating obesity |
| WO2008124838A1 (en) * | 2007-04-10 | 2008-10-16 | University Of Maryland, Baltimore | Compounds that inhibit human dna ligases and methods of treating cancer |
| JPWO2009028280A1 (ja) * | 2007-08-29 | 2010-11-25 | 三井化学アグロ株式会社 | ピラゾールカルボン酸誘導体及びその製造方法、並びに殺菌剤 |
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| AU2008345225A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| EP2238127B1 (en) | 2007-12-26 | 2012-08-15 | Sanofi | Pyrazole-carboxamide derivatives as p2y12 antagonists |
| EP2238128B1 (en) | 2007-12-26 | 2012-08-22 | Sanofi | Heterocyclic pyrazole-carboxamides as p2y12 antagonists |
| JP5411927B2 (ja) * | 2008-05-06 | 2014-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ccr1アンタゴニストとしてのピラゾール化合物 |
| US7863309B2 (en) * | 2008-07-24 | 2011-01-04 | Theravance, Inc. | Dual-acting antihypertensive agents |
| PL2435409T3 (pl) * | 2009-05-28 | 2015-01-30 | Novartis Ag | Podstawione pochodne aminopropionowe jako inhibitory neprylizyny |
| US7956054B2 (en) * | 2009-07-07 | 2011-06-07 | Theravance, Inc. | Dual-acting pyrazole antihypertensive agents |
| EP2456762B1 (en) * | 2009-07-22 | 2013-10-16 | Theravance, Inc. | Dual-acting oxazole antihypertensive agents |
| UY33200A (es) * | 2010-01-26 | 2011-08-31 | Sanofi Aventis | Derivados de ácido 3-heteroaroilamino-propiónico sustituidos con oxígeno y su uso como productos farmacéuticos |
| ES2602835T3 (es) * | 2011-05-17 | 2017-02-22 | Waterdiam Sàrl | Método para tratar cítricos después de la cosecha |
| ES2653215T3 (es) * | 2011-05-31 | 2018-02-06 | Theravance Biopharma R&D Ip, Llc | Inhibidores de neprilisina |
| WO2013014204A2 (en) | 2011-07-26 | 2013-01-31 | Sanofi | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals |
-
2012
- 2012-07-25 WO PCT/EP2012/064628 patent/WO2013014204A2/en not_active Ceased
- 2012-07-25 HR HRP20160047TT patent/HRP20160047T1/hr unknown
- 2012-07-25 EP EP15190731.8A patent/EP3037417B1/en not_active Not-in-force
- 2012-07-25 SI SI201230439T patent/SI2736888T1/sl unknown
- 2012-07-25 CA CA2841905A patent/CA2841905A1/en not_active Abandoned
- 2012-07-25 CN CN201511021647.3A patent/CN105646362B/zh not_active Expired - Fee Related
- 2012-07-25 JP JP2014522086A patent/JP6021910B2/ja not_active Expired - Fee Related
- 2012-07-25 PT PT127384733T patent/PT2736888E/pt unknown
- 2012-07-25 ES ES12738473.3T patent/ES2560381T3/es active Active
- 2012-07-25 EP EP12738473.3A patent/EP2736888B1/en not_active Not-in-force
- 2012-07-25 MY MYPI2013004643A patent/MY169319A/en unknown
- 2012-07-25 RU RU2014107000/04A patent/RU2014107000A/ru not_active Application Discontinuation
- 2012-07-25 AU AU2012288842A patent/AU2012288842A1/en not_active Abandoned
- 2012-07-25 DK DK12738473.3T patent/DK2736888T3/da active
- 2012-07-25 BR BR112014001518A patent/BR112014001518A2/pt not_active IP Right Cessation
- 2012-07-25 CN CN201280046863.1A patent/CN103827097B/zh not_active Expired - Fee Related
- 2012-07-25 KR KR1020147004756A patent/KR20140049019A/ko not_active Withdrawn
- 2012-07-25 MX MX2014000598A patent/MX337173B/es active IP Right Grant
- 2012-07-25 PL PL12738473T patent/PL2736888T3/pl unknown
- 2012-07-25 HU HUE12738473A patent/HUE028418T2/en unknown
- 2012-07-26 US US13/559,401 patent/US9353068B2/en not_active Expired - Fee Related
-
2013
- 2013-12-23 IL IL230126A patent/IL230126A/en not_active IP Right Cessation
-
2016
- 2016-02-03 CY CY20161100093T patent/CY1117397T1/el unknown
- 2016-04-27 US US15/140,350 patent/US9751858B2/en not_active Expired - Fee Related
- 2016-09-30 JP JP2016192793A patent/JP6360534B2/ja not_active Expired - Fee Related
- 2016-12-06 HK HK16113874.6A patent/HK1225714A1/zh unknown
-
2017
- 2017-01-31 IL IL250370A patent/IL250370A0/en unknown
- 2017-06-02 AU AU2017203739A patent/AU2017203739A1/en not_active Abandoned
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