PL2768848T3 - Środki i sposoby ekspresji i wydzielania peptydów i białek - Google Patents

Środki i sposoby ekspresji i wydzielania peptydów i białek

Info

Publication number
PL2768848T3
PL2768848T3 PL12777908T PL12777908T PL2768848T3 PL 2768848 T3 PL2768848 T3 PL 2768848T3 PL 12777908 T PL12777908 T PL 12777908T PL 12777908 T PL12777908 T PL 12777908T PL 2768848 T3 PL2768848 T3 PL 2768848T3
Authority
PL
Poland
Prior art keywords
secretion
peptides
proteins
expression
agents
Prior art date
Application number
PL12777908T
Other languages
English (en)
Inventor
Christian Schwarz
Lutz Schmitt
Sander Hendrikus Joannes Smits
Original Assignee
Numaferm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Numaferm Gmbh filed Critical Numaferm Gmbh
Publication of PL2768848T3 publication Critical patent/PL2768848T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL12777908T 2011-10-21 2012-10-22 Środki i sposoby ekspresji i wydzielania peptydów i białek PL2768848T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11186225.6A EP2583975A1 (en) 2011-10-21 2011-10-21 Agents and methods for the expression and secretion of peptides and proteins
PCT/EP2012/070880 WO2013057312A1 (en) 2011-10-21 2012-10-22 Agents and methods for the expression and secretion of peptides and proteins
EP12777908.0A EP2768848B1 (en) 2011-10-21 2012-10-22 Agents and methods for the expression and secretion of peptides and proteins

Publications (1)

Publication Number Publication Date
PL2768848T3 true PL2768848T3 (pl) 2019-01-31

Family

ID=47073445

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12777908T PL2768848T3 (pl) 2011-10-21 2012-10-22 Środki i sposoby ekspresji i wydzielania peptydów i białek

Country Status (7)

Country Link
US (1) US9493804B2 (pl)
EP (3) EP2583975A1 (pl)
DK (1) DK2768848T3 (pl)
ES (1) ES2689245T3 (pl)
PL (1) PL2768848T3 (pl)
PT (1) PT2768848T (pl)
WO (1) WO2013057312A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2792686A1 (en) 2013-04-17 2014-10-22 Heinrich-Heine-Universität Düsseldorf Methods for the expression of peptides and proteins
US12351805B2 (en) 2015-11-19 2025-07-08 Northeastern University Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria
WO2017087827A1 (en) * 2015-11-19 2017-05-26 President And Fellows Of Harvard College Method of making recombinant silk andsilk-amyloid hybrid proteins using bacteria
EP3630807B1 (en) 2017-05-25 2025-08-13 Leidos, Inc. Pd-1 and ctla-4 dual inhibitor peptides
AU2020279371A1 (en) 2019-05-22 2021-12-23 Leidos, Inc. LAG 3 binding peptides
EP3892290A1 (en) 2020-04-08 2021-10-13 NUMAFERM GmbH Variants of hlya and uses thereof
WO2022194375A1 (en) 2020-03-18 2022-09-22 Numaferm Gmbh Fusion proteins comprising gg repeat sequences
EP3882260A1 (en) * 2020-03-18 2021-09-22 NUMAFERM GmbH Fragments of hlya and uses thereof
AU2021316230A1 (en) 2020-07-31 2023-03-16 Leidos, Inc. LAG3 binding peptides
US20240228553A1 (en) * 2021-03-18 2024-07-11 Numaferm Gmbh Fusion proteins comprising gg repeat sequences
CN113354723A (zh) * 2021-04-29 2021-09-07 中山大学 吉富罗非鱼神经分泌肽gl及其应用
EP4339202A1 (en) 2022-09-16 2024-03-20 NUMAFERM GmbH Fusion proteins comprising gg repeat sequences ii
EP4737471A1 (en) 2024-10-29 2026-05-06 NUMAFERM GmbH Methods for the c-terminal modification of (poly)peptides
WO2025247862A1 (en) 2024-05-27 2025-12-04 Numaferm Gmbh Methods for the c-terminal modification of (poly)peptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) * 1986-05-15 1986-06-25 Holland I B Polypeptide
US20030165870A1 (en) * 2002-03-01 2003-09-04 Blattner Frederick R. Novel sequences of E. coli CFT073
CA2428646A1 (en) * 2003-04-30 2004-10-30 National Research Council Of Canada Array and uses thereof
US20060094034A1 (en) * 2003-04-30 2006-05-04 Roland Brousseau Virulence and antibiotic resistance array and uses thereof
EP1921149A1 (en) * 2006-11-13 2008-05-14 AEterna Zentaris GmbH Microorganisms as carriers of nucleotide sequences coding for antigens and protein toxins, process of manufacturing and uses thereof

Also Published As

Publication number Publication date
EP2768848A1 (en) 2014-08-27
US20140343251A1 (en) 2014-11-20
EP2768848B1 (en) 2018-07-04
EP2583975A1 (en) 2013-04-24
EP3210997C0 (en) 2023-07-26
WO2013057312A1 (en) 2013-04-25
PT2768848T (pt) 2018-10-26
EP3210997B1 (en) 2023-07-26
DK2768848T3 (en) 2018-10-08
EP3210997A1 (en) 2017-08-30
US9493804B2 (en) 2016-11-15
ES2689245T3 (es) 2018-11-12

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