PL2773331T3 - Preparaty do leczenia cukrzycy - Google Patents

Preparaty do leczenia cukrzycy

Info

Publication number
PL2773331T3
PL2773331T3 PL12798470T PL12798470T PL2773331T3 PL 2773331 T3 PL2773331 T3 PL 2773331T3 PL 12798470 T PL12798470 T PL 12798470T PL 12798470 T PL12798470 T PL 12798470T PL 2773331 T3 PL2773331 T3 PL 2773331T3
Authority
PL
Poland
Prior art keywords
diabetes
formulations
treatment
Prior art date
Application number
PL12798470T
Other languages
English (en)
Inventor
Steven Prestrelski
Nancy Scott
Original Assignee
Xeris Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xeris Pharmaceuticals Inc filed Critical Xeris Pharmaceuticals Inc
Publication of PL2773331T3 publication Critical patent/PL2773331T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
PL12798470T 2011-10-31 2012-10-31 Preparaty do leczenia cukrzycy PL2773331T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161553388P 2011-10-31 2011-10-31
US201261609123P 2012-03-09 2012-03-09
EP12798470.6A EP2773331B1 (en) 2011-10-31 2012-10-31 Formulations for the treatment of diabetes
PCT/US2012/062816 WO2013067022A1 (en) 2011-10-31 2012-10-31 Formulations for the treatment of diabetes

Publications (1)

Publication Number Publication Date
PL2773331T3 true PL2773331T3 (pl) 2016-08-31

Family

ID=47324375

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12798470T PL2773331T3 (pl) 2011-10-31 2012-10-31 Preparaty do leczenia cukrzycy

Country Status (16)

Country Link
US (1) US9138479B2 (pl)
EP (1) EP2773331B1 (pl)
JP (1) JP6117811B2 (pl)
KR (1) KR102007057B1 (pl)
CN (1) CN103930096B (pl)
AU (1) AU2012332556B2 (pl)
BR (1) BR112014010275A2 (pl)
CA (1) CA2853942C (pl)
DK (1) DK2773331T3 (pl)
EA (1) EA027744B1 (pl)
ES (1) ES2574761T3 (pl)
MX (1) MX349383B (pl)
PL (1) PL2773331T3 (pl)
SG (1) SG11201401921YA (pl)
WO (1) WO2013067022A1 (pl)
ZA (1) ZA201403795B (pl)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853348B (zh) * 2011-03-10 2019-08-30 Xeris药物公司 肠胃外注射用稳定溶液
US9125805B2 (en) 2012-06-27 2015-09-08 Xeris Pharmaceuticals, Inc. Stable formulations for parenteral injection of small molecule drugs
MX360420B (es) * 2012-12-19 2018-10-31 Wockhardt Ltd Una composicion acuosa estable que comprende insulina humana o un analogo o derivado de la misma.
US9018162B2 (en) 2013-02-06 2015-04-28 Xeris Pharmaceuticals, Inc. Methods for rapidly treating severe hypoglycemia
KR102351111B1 (ko) * 2014-01-13 2022-01-14 써멀린 다이어비티즈, 엘엘씨 초속효성 인슐린 제형 및 약제학적 전달 시스템
EP3102184B1 (en) * 2014-02-06 2019-01-30 Xeris Pharmaceuticals, Inc. Stable peptide formulations and methods for preparation
WO2015153728A1 (en) 2014-04-02 2015-10-08 Xeris Pharmaceuticals, Inc. Polar aprotic solvent-compatible infusion sets, components, and methods
AU2015300944B2 (en) 2014-08-06 2019-07-11 Xeris Pharmaceuticals, Inc. Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes
US9649364B2 (en) * 2015-09-25 2017-05-16 Xeris Pharmaceuticals, Inc. Methods for producing stable therapeutic formulations in aprotic polar solvents
WO2016196976A1 (en) * 2015-06-04 2016-12-08 Xeris Pharmaceuticals, Inc. Glucagon delivery apparatuses and related methods
EP3307295A1 (en) * 2015-06-10 2018-04-18 Xeris Pharmaceuticals, Inc. Use of low dose glucagon
US11590205B2 (en) 2015-09-25 2023-02-28 Xeris Pharmaceuticals, Inc. Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents
EP3518893A1 (en) * 2016-09-29 2019-08-07 Arecor Limited Novel formulations
JP7022746B2 (ja) * 2016-10-24 2022-02-18 ノヴォ ノルディスク アー/エス インスリン製剤のためのバイオアッセイ
CN106310232A (zh) * 2016-10-25 2017-01-11 南京师范大学 一种稳定的胰岛素解聚体超分子复合物及其制备方法
EP3562500B1 (fr) 2016-12-27 2023-07-19 Adocia Compositions sous forme de solution aqueuse injectable comprenant de l'amyline, un agoniste au récepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
CA3059985C (en) 2017-05-05 2023-08-08 Eli Lilly And Company Closed loop control of physiological glucose
BR112019024987A2 (pt) 2017-06-02 2020-06-16 Xeris Pharmaceuticals, Inc. Formulações de fármaco de molécula pequena resistente à precipitação
FR3082426A1 (fr) 2018-06-14 2019-12-20 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant au moins de l'insuline humaine a21g et un suppresseur de glucagon a action prandiale
PL3658115T4 (pl) * 2017-07-27 2022-08-08 Adocia Kompozycje w postaci wodnego roztworu do wstrzykiwań zawierające co najmniej insulinę ludzką a21g i co najmniej jeden supresor glukagonu o działaniu prandialnym
WO2019115411A1 (fr) 2017-12-07 2019-06-20 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
FR3083085B1 (fr) 2018-06-29 2020-10-02 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
BR112020011479A2 (pt) 2017-12-07 2020-11-17 Adocia composições na forma de uma solução aquosa injetável caracterizada pelo fato de que compreende amilina, um agonista do receptor de amilina ou um análogo de amilina e um co-poliaminoácido
KR20240171194A (ko) 2017-12-07 2024-12-06 아도시아 아밀린, 아밀린 작용제 수용체 또는 아밀린 유사체 및 코-폴리아미노산을 포함하는 주사용 수용액 형태의 조성물
FR3083086A1 (fr) 2018-06-29 2020-01-03 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
EP3740195A1 (fr) 2017-12-07 2020-11-25 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
CA3085930A1 (en) 2017-12-21 2019-06-27 Eli Lilly And Company Closed loop control of physiological glucose
JP2021528758A (ja) * 2018-06-22 2021-10-21 イーライ リリー アンド カンパニー インスリンとプラムリンタイドの送達システム、方法、およびデバイス
FR3084586B1 (fr) 2018-08-03 2020-11-06 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un compose amphiphile porteur de radicaux hydrophobes
US11439606B2 (en) 2018-12-03 2022-09-13 Guadalupe Cleva Villanueva Lopez Reduction of hyperglycemia by administration of dimethylformamide for treating hyperglycemic conditions, including diabetes mellitus
AU2020219125B2 (en) 2019-02-05 2025-10-02 Lindy Biosciences, Inc. Isolated cell culture components and methods for isolating the same from liquid cell culture medium
WO2020168003A1 (en) * 2019-02-12 2020-08-20 The Board Of Trustees Of The Leland Stanford Junior University Co-formulations of amylin analogues with insulin analogues for treatment of diabetes
EP3975993A1 (en) 2019-05-31 2022-04-06 Xeris Pharmaceuticals, Inc. Stable therapeutic compositions in aprotic polar solvents and methods of manufacturing the same
EP4072577A4 (en) * 2019-12-13 2024-02-14 The Board of Trustees of the Leland Stanford Junior University STABLE MONOMERIC INSULIN FORMULATIONS BY SUPRAMOLECULAR PEGYLATION OF INSULIN ANALOGS

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3016895A (en) 1958-08-01 1962-01-16 Pan American Lab Inc Injector for subcutaneous implantation of solids
US5260306A (en) 1981-07-24 1993-11-09 Fisons Plc Inhalation pharmaceuticals
GB2119248A (en) * 1982-04-28 1983-11-16 John Kenneth Mcmullen Insulin formulations and method of producing them
CH664005A5 (de) 1984-05-19 1988-01-29 Glatt Maschinen & Apparatebau Verfahren zum trocknen eines teilchenfoermigen gutes und einrichtung zur durchfuehrung des verfahrens.
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US4927571A (en) 1987-05-18 1990-05-22 Liposome Technology, Inc. Preparation of injectable doxorubicin/liposome suspension
US4848094A (en) 1988-04-29 1989-07-18 Union Carbide Corporation Droplet freezing method and apparatus
US5031336A (en) 1989-08-31 1991-07-16 Abbott Laboratories Lyophilization of bulk pharmaceuticals
US5092843A (en) 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
CA2081474A1 (en) 1990-05-08 1991-11-09 Manzer Durrani Direct spray-dried drug/lipid powder composition
US5208998A (en) 1991-02-25 1993-05-11 Oyler Jr James R Liquid substances freeze-drying systems and methods
JP3277342B2 (ja) 1992-09-02 2002-04-22 武田薬品工業株式会社 徐放性マイクロカプセルの製造法
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US5652216A (en) 1994-05-26 1997-07-29 Novo Nordisk A/S Pharmaceutical preparation
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
KR970705979A (ko) 1994-09-29 1997-11-03 디 히스 치료용 매개체로서의 분무-건조 미소입자 (Spray-dried microparticles as therapeutic vehicles)
US5932547A (en) * 1996-07-03 1999-08-03 Alza Corporation Non-aqueous polar aprotic peptide formulations
US5945128A (en) 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
IN184589B (pl) 1996-10-16 2000-09-09 Alza Corp
JP2002512597A (ja) 1996-12-20 2002-04-23 アルザ コーポレイション 注射可能な貯留槽ゲル組成物およびこの組成物の製造方法
AU5806998A (en) 1996-12-31 1998-07-31 Inhale Therapeutic Systems Processes for spray drying solutions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
ZA984697B (en) * 1997-06-13 1999-12-01 Lilly Co Eli Stable insulin formulations.
DK0916347T3 (da) 1997-11-18 2003-04-22 Uni Pharma Kleon Tsetis A B E Farmaceutiske injicerbare opløsninger der indeholder paracetamol og kombinationer af paracetamol med andre aktive bestanddele
FR2783433B1 (fr) 1998-09-18 2001-02-16 Delab Seringues pour l'administration de formulations pateuses ou semi-solides
SE9803662D0 (sv) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab Autoinjector
US6199297B1 (en) 1999-02-01 2001-03-13 Integrated Biosystems, Inc. Lyophilization apparatus and methods
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US6253463B1 (en) 1999-04-26 2001-07-03 Niro A/S Method of spray drying
US6309663B1 (en) 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
FR2801226B1 (fr) * 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
US6478776B1 (en) 2000-04-05 2002-11-12 Biocardia, Inc. Implant delivery catheter system and methods for its use
WO2001078687A1 (en) 2000-04-18 2001-10-25 Peptron Inc. Injectable sustained release pharmaceutical composition and processes for preparing the same
US6495164B1 (en) 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
CN1283215C (zh) 2000-06-28 2006-11-08 A·J·舒克拉 生物活性物质的可生物降解载体和释放系统
CA2419067C (en) 2000-08-18 2008-12-23 Takeda Chemical Industries, Ltd. Injectable composition comprising benzimidazole compound and strong alkali
FR2814951B1 (fr) * 2000-10-06 2003-01-17 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation
RO120121B1 (ro) 2000-12-18 2005-09-30 Elena Ionaşcu Soluţie injectabilă, cu efect antiinflamator, procedeu de obţinere şi metodă de tratament a bolilor autoimune
US6676958B2 (en) 2001-06-19 2004-01-13 Advanced Bioadjuvants, Llc Adjuvant composition for mucosal and injection delivered vaccines
JP4490095B2 (ja) 2001-06-29 2010-06-23 メドグラフト マイクロテック インコーポレイテッド 生体分解性の注入可能な移植物およびそれに関連する製造方法ならびに使用方法
EP1413310A1 (en) 2001-07-09 2004-04-28 Yamanouchi Pharmaceutical Co. Ltd. Sustained-release compositions for injection and process for producing the same
US6733813B2 (en) 2001-08-02 2004-05-11 Ocean Spray Cranberries, Inc. Process for producing acids-enriched juice and acids-reduced juice
CA2466632C (en) 2001-11-14 2014-02-11 Alza Corporation Injectable depot compositions and uses thereof
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
CN1582170B (zh) 2001-12-18 2010-05-05 联合制药克伦茨蒂斯药物实验室公司 扑热息痛的肠胃外组合物
CN1171610C (zh) 2002-04-23 2004-10-20 张瑞香 一种治疗心脑血管和眼底病的中药针剂及其制备方法
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
EP1558234B1 (en) 2002-10-25 2007-05-23 Dompé S.P.A. Painless injectable compositions containing salt of 2-arylpropionic acids
CN102205127A (zh) 2002-12-18 2011-10-05 阿尔乔医疗公司 类辣椒素的给药
WO2004057959A2 (en) 2002-12-20 2004-07-15 Generipharm, Inc. Intracutaneous injection
ES2298672T3 (es) 2003-04-14 2008-05-16 Wyeth Holdings Corporation Composiciones que contienen piperacilina y tazobactam utiles para inyeccion.
WO2004098643A1 (en) 2003-04-14 2004-11-18 Wyeth Holdings Corporation Compositions containing piperacillin and tazobactam useful for injection
KR100517643B1 (ko) 2003-07-25 2005-09-28 한국과학기술연구원 온도 감응성 폴리포스파젠계 고분자, 이의 제조방법 및이를 이용한 주입형 온도 감응성 폴리포스파젠 하이드로젤
SI1502589T1 (sl) 2003-07-31 2006-12-31 Emdoka Bvba Drug Registration Veterinarske vodne injektibilne suspenzije, ki vsebujejo florfenikol
US20050100538A1 (en) 2003-07-31 2005-05-12 Attawia Mohamed Intradiscal injection of anti-oxidants
PL1658171T3 (pl) 2003-08-22 2008-10-31 Singulus Tech Ag Sposób łączenia substratów do wytwarzania dysków optycznych, oraz urządzenie do realizacji tego sposobu
US20050069591A1 (en) 2003-09-30 2005-03-31 Howard Bernstein Injectable, oral, or topical sustained release pharmaceutical formulations
US20080248999A1 (en) * 2007-04-04 2008-10-09 Biodel Inc. Amylin formulations
EP1987843A3 (en) 2004-03-12 2011-10-26 Intercell AG Method for solubilising peptide mixtures
US20060160823A1 (en) 2004-05-28 2006-07-20 Leonore Witchey-Lakshmanan Particulate-stabilized injectable pharmaceutical compositions of Posaconazole
CN101056643A (zh) 2004-09-13 2007-10-17 Pr药品有限公司 雌二醇代谢物的长效可注射晶体制剂及其应用方法
JP5069130B2 (ja) 2005-01-27 2012-11-07 エリモス・ファーマスーティカルズ・エルエルシー Ndga化合物を包含するカテコールブタンの送達のための経口用製剤
EP1909824B1 (en) 2005-04-08 2011-05-18 Amylin Pharmaceuticals, Inc. Pharmaceutical formulations comprising incretin peptide and aprotic polar solvent
US20080305161A1 (en) 2005-04-13 2008-12-11 Pfizer Inc Injectable depot formulations and methods for providing sustained release of nanoparticle compositions
AU2007207618B2 (en) 2006-01-18 2011-03-24 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical compositions with enhanced stability
AR054215A1 (es) 2006-01-20 2007-06-13 Eriochem Sa Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit
US20070275030A1 (en) 2006-05-25 2007-11-29 The General Hospital Corporation Dba Massachusetts General Hospital Anti-cross-linking agents and methods for inhibiting cross-linking of injectable hydrogel formulations
CA2662827C (en) 2006-09-07 2015-04-07 Merial Limited Soft chewable, tablet, and long-acting injectable veterinary antibiotic formulations
CA2665101A1 (en) 2006-10-05 2008-04-10 Panacea Biotec Ltd. Injectable depot composition and it's process of preparation
WO2008098212A2 (en) 2007-02-08 2008-08-14 Diobex, Inc. Extended release formulations of glucagon and other peptides and proteins
CA2683610C (en) 2007-04-23 2013-01-08 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
JP5496082B2 (ja) 2007-04-30 2014-05-21 ノボ・ノルデイスク・エー/エス タンパク質組成物を乾燥させる方法、乾燥タンパク質組成物、及び乾燥タンパク質を含有する薬学的組成物
EP2152243A2 (en) * 2007-04-30 2010-02-17 Novo Nordisk A/S Highly concentrated insulin solutions and compositions
TW200922635A (en) 2007-08-31 2009-06-01 Archimedes Dev Ltd Non-aqueous pharmaceutical compositions
US20090088393A1 (en) 2007-09-28 2009-04-02 Zomanex, Llc Methods and formulations for converting intravenous and injectable drugs into oral dosage forms
CL2008003305A1 (es) 2007-11-06 2009-06-05 M/S Panacea Biotec Ltd Composicion inyectable que comprende un agente activo seleccionado de un grupo definido; al menos un polimero bioerosionable, al menos un solvente no toxico y opcionalmente uno o mas excipientes; proceso de preparacion; uso para tratar enfermedades mentales o cancer.
EP2060268A1 (en) * 2007-11-15 2009-05-20 Novo Nordisk A/S Pharmaceutical compositions for pulmonary or nasal delivery of peptides
CN101877963A (zh) 2007-11-28 2010-11-03 泰华制药工业有限公司 延缓临床确诊的多发性硬化症发作的方法
EP2249809A1 (en) 2008-01-15 2010-11-17 Abbott GmbH & Co. KG Powdered protein compositions and methods of making same
MX2011000795A (es) 2008-07-23 2011-03-29 Bharat Serums & Vaccines Ltd Nanoemulsion estable inyectable de docetaxel de aceite en agua.
GB2481017B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
WO2012012460A1 (en) 2010-07-19 2012-01-26 Xeris Pharmaceuticals, Inc. Stable glucagon formulations for the treatment of hypoglycemia
CN105853348B (zh) 2011-03-10 2019-08-30 Xeris药物公司 肠胃外注射用稳定溶液

Also Published As

Publication number Publication date
JP2014532667A (ja) 2014-12-08
KR102007057B1 (ko) 2019-08-02
EP2773331B1 (en) 2016-02-10
MX349383B (es) 2017-07-26
KR20140107228A (ko) 2014-09-04
US20140349926A1 (en) 2014-11-27
CA2853942C (en) 2020-08-25
EP2773331A1 (en) 2014-09-10
CA2853942A1 (en) 2013-05-10
AU2012332556B2 (en) 2016-05-26
CN103930096B (zh) 2017-05-31
CN103930096A (zh) 2014-07-16
ES2574761T3 (es) 2016-06-21
BR112014010275A2 (pt) 2017-04-18
WO2013067022A1 (en) 2013-05-10
EA027744B1 (ru) 2017-08-31
EA201490913A1 (ru) 2014-09-30
SG11201401921YA (en) 2014-05-29
AU2012332556A1 (en) 2014-06-19
US9138479B2 (en) 2015-09-22
ZA201403795B (en) 2016-01-27
JP6117811B2 (ja) 2017-04-19
DK2773331T3 (en) 2016-03-14
MX2014005311A (es) 2014-10-06

Similar Documents

Publication Publication Date Title
ZA201403795B (en) Formulations for the treatment of diabetes
IL232251A0 (en) Protocol for the treatment of type 2 diabetes
AP2014007533A0 (en) Substituted benzylindazoles for use as BUB1 kinaseinhibitors in the treatment of hyperproliferative diseases
EP2609848A4 (en) Borescope
SG2014014724A (en) METHODS FOR THE TREATMENT OF IL-1ß RELATED CONDITIONS
IL223289A0 (en) Treatment of type 2 diabetes
IL232239A0 (en) Medical use
HUP1100290A2 (en) Combination compositions for the treatment of proliferative diseases
IL234796B (en) Compounds for the treatment of diseases related to ischemia-reperfusion
ZA201408065B (en) Compositions and methods for the treatment of diabetes
ZA201308117B (en) Avian-based treatment
HUE047357T2 (hu) Gyógyászati kezelés
GB201102283D0 (en) Treatment
IL232294B (en) Preparations for the treatment of diabetes
GB201106981D0 (en) Compounds for the treatment of clostridium difficle-associated disease
GB201110659D0 (en) composition for skin treatment
GB201110653D0 (en) Composition for skin treatment
AP2015008270A0 (en) Preparation for the treatment of tuberculosis
GB201119533D0 (en) Compounds for the treatment of neoplasia
GB201102273D0 (en) Treatment
GB201102265D0 (en) Treatment
GB201111247D0 (en) Treatment
GB201102269D0 (en) Treatment
GB201102275D0 (en) Treatment
GB201102267D0 (en) Treatment