PL2776382T3 - 18f-sacharydo-foliany - Google Patents

18f-sacharydo-foliany

Info

Publication number
PL2776382T3
PL2776382T3 PL12748492T PL12748492T PL2776382T3 PL 2776382 T3 PL2776382 T3 PL 2776382T3 PL 12748492 T PL12748492 T PL 12748492T PL 12748492 T PL12748492 T PL 12748492T PL 2776382 T3 PL2776382 T3 PL 2776382T3
Authority
PL
Poland
Prior art keywords
folates
saccharide
Prior art date
Application number
PL12748492T
Other languages
English (en)
Inventor
Roger Schibli
Rudolf Moser
Cristina Magdalena MÜLLER
Simon Mensah Ametamey
Cindy Ramona FISCHER
Viola Groehn
Original Assignee
Merck & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Cie filed Critical Merck & Cie
Publication of PL2776382T3 publication Critical patent/PL2776382T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/005—Sugars; Derivatives thereof; Nucleosides; Nucleotides; Nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nuclear Medicine (AREA)
  • Saccharide Compounds (AREA)
PL12748492T 2011-08-22 2012-08-21 18f-sacharydo-foliany PL2776382T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11178260 2011-08-22
EP12748492.1A EP2776382B1 (en) 2011-08-22 2012-08-21 18f-saccharide-folates
PCT/EP2012/066236 WO2013026842A1 (en) 2011-08-22 2012-08-21 18f-saccharide-folates

Publications (1)

Publication Number Publication Date
PL2776382T3 true PL2776382T3 (pl) 2019-05-31

Family

ID=46704677

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12748492T PL2776382T3 (pl) 2011-08-22 2012-08-21 18f-sacharydo-foliany

Country Status (17)

Country Link
US (2) US10322195B2 (pl)
EP (1) EP2776382B1 (pl)
JP (1) JP6161209B2 (pl)
KR (1) KR101994327B1 (pl)
CN (1) CN103732563B (pl)
AU (2) AU2012298546A1 (pl)
CA (1) CA2839654C (pl)
DK (1) DK2776382T3 (pl)
EA (1) EA201400253A1 (pl)
ES (1) ES2703107T3 (pl)
IL (1) IL230760A (pl)
PL (1) PL2776382T3 (pl)
PT (1) PT2776382T (pl)
SG (2) SG2014001085A (pl)
TR (1) TR201819447T4 (pl)
WO (1) WO2013026842A1 (pl)
ZA (1) ZA201400175B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
TWI732825B (zh) * 2016-05-20 2021-07-11 日商王子控股股份有限公司 圖案形成用定向自組裝組成物、圖案形成用定向自組裝組成物用單體及圖案形成方法
CN109232690A (zh) * 2018-09-10 2019-01-18 南方医科大学南方医院 一种正电子显像剂标准品前体及其制备方法
EP3671511B1 (en) 2018-12-19 2022-07-06 Rohde & Schwarz GmbH & Co. KG Communication system and method
CN111714640B (zh) * 2019-03-14 2023-02-14 北京和益源生物技术有限公司 一种糖修饰的叶酸衍生物制备的纳米运载颗粒及其应用
CN111748002B (zh) * 2019-03-14 2022-03-29 北京和益源生物技术有限公司 一种脱氧葡萄糖修饰的叶酸衍生物及其合成与应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276280A (en) 1976-09-29 1981-06-30 Becton, Dickinson And Company Radiolabeled derivatives of folic acid
US4628090A (en) 1984-08-21 1986-12-09 Rensselaer Polytechnic Institute Fluorine-containing antifolates incapable of polyglutanayte formation related compounds
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
ES2566761T3 (es) 2002-05-30 2016-04-15 The Scripps Research Institute Ligación de azidas y acetilenos catalizada por cobre
CN101128152A (zh) 2004-12-23 2008-02-20 普渡研究基金会 发射正电子段层成像方法
KR20080000620A (ko) 2005-04-27 2008-01-02 지멘스 메디컬 솔루션즈 유에스에이, 인크. 분자 이미징 프로브를 합성하기 위한 클릭 화학 방법
US8926945B2 (en) * 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
US8586595B2 (en) 2007-02-07 2013-11-19 Purdue Research Foundation Positron emission tomography imaging method
DK2146944T3 (da) * 2007-04-11 2014-02-03 Merck & Cie Fremgangsmåde til fremstillingen af 18f-mærkede folater
PT2144912E (pt) 2007-04-11 2013-02-01 Merck & Cie Folatos marcados com 18f
JP5693950B2 (ja) * 2007-04-11 2015-04-01 メルク エ カンパニー １８ｆ標識葉酸
EP2194068B1 (en) * 2007-09-28 2013-04-17 Nanodex INC. Cyclodextrin compound modified with folic acid, process for production thereof, drug delivery agent for targeting drug delivery system, pharmaceutical composition, and imaging agent
ES2548140T3 (es) * 2008-10-10 2015-10-14 Merck & Cie Folatos marcados con 18F como radiotrazadores PET
WO2013024035A1 (en) * 2011-08-17 2013-02-21 Merck & Cie Folate conjugates of albumin-binding entities

Also Published As

Publication number Publication date
HK1194355A1 (zh) 2014-10-17
TR201819447T4 (tr) 2019-01-21
EA201400253A1 (ru) 2014-08-29
IL230760A0 (en) 2014-03-31
IL230760A (en) 2017-08-31
CN103732563B (zh) 2016-04-20
JP6161209B2 (ja) 2017-07-12
AU2017203512B2 (en) 2019-02-28
JP2014531411A (ja) 2014-11-27
US20140193337A1 (en) 2014-07-10
AU2012298546A1 (en) 2014-02-20
CA2839654C (en) 2021-02-16
EP2776382B1 (en) 2018-09-19
WO2013026842A1 (en) 2013-02-28
ZA201400175B (en) 2015-08-26
US20190255200A1 (en) 2019-08-22
CN103732563A (zh) 2014-04-16
EP2776382A1 (en) 2014-09-17
ES2703107T3 (es) 2019-03-07
DK2776382T3 (en) 2019-01-14
AU2017203512A1 (en) 2017-06-15
US10322195B2 (en) 2019-06-18
SG10201606981QA (en) 2016-10-28
PT2776382T (pt) 2018-12-24
US10973936B2 (en) 2021-04-13
KR20140054284A (ko) 2014-05-08
KR101994327B1 (ko) 2019-06-28
CA2839654A1 (en) 2013-02-28
SG2014001085A (en) 2014-03-28

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