PL2781519T3 - Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzania - Google Patents
Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzaniaInfo
- Publication number
- PL2781519T3 PL2781519T3 PL12849140T PL12849140T PL2781519T3 PL 2781519 T3 PL2781519 T3 PL 2781519T3 PL 12849140 T PL12849140 T PL 12849140T PL 12849140 T PL12849140 T PL 12849140T PL 2781519 T3 PL2781519 T3 PL 2781519T3
- Authority
- PL
- Poland
- Prior art keywords
- same
- production method
- novel antiviral
- pyrrolopyridine derivative
- pyrrolopyridine
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000005255 pyrrolopyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20110119102 | 2011-11-15 | ||
| EP12849140.4A EP2781519B1 (en) | 2011-11-15 | 2012-11-15 | Novel antiviral pyrrolopyridine derivative and a production method for same |
| PCT/KR2012/009689 WO2013073875A1 (ko) | 2011-11-15 | 2012-11-15 | 신규한 항바이러스성 피롤로피리딘 유도체 및 이의 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2781519T3 true PL2781519T3 (pl) | 2020-06-29 |
Family
ID=48429876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12849140T PL2781519T3 (pl) | 2011-11-15 | 2012-11-15 | Nowa przeciwwirusowa pochodna pirolopirydyny i sposób jej wytwarzania |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9499537B2 (pl) |
| EP (1) | EP2781519B1 (pl) |
| JP (1) | JP5893156B2 (pl) |
| KR (1) | KR101467477B1 (pl) |
| CN (1) | CN104066732B (pl) |
| DK (1) | DK2781519T3 (pl) |
| ES (1) | ES2760981T3 (pl) |
| HU (1) | HUE046795T2 (pl) |
| PL (1) | PL2781519T3 (pl) |
| PT (1) | PT2781519T (pl) |
| WO (1) | WO2013073875A1 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2876370A1 (en) | 2012-07-12 | 2014-01-16 | Viiv Healthcare Uk Limited | Compounds and methods for treating hiv |
| TW201441197A (zh) | 2013-01-31 | 2014-11-01 | Shionogi & Co | Ｈｉｖ複製抑制劑 |
| EP2821082A1 (en) | 2013-07-05 | 2015-01-07 | Laboratoire Biodim | Method of producing an inactivated lentivirus, especially HIV, vaccine, kit and method of use |
| EP3105236B1 (en) | 2014-02-12 | 2017-10-18 | ViiV Healthcare UK (No.5) Limited | Benzothiazole macrocycles as inhibitors of human immunodeficiency virus replication |
| WO2015126758A1 (en) | 2014-02-18 | 2015-08-27 | Bristol-Myers Squibb Company | Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9409922B2 (en) | 2014-02-18 | 2016-08-09 | Bristol-Myers Squibb Company | Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9834566B2 (en) | 2014-02-18 | 2017-12-05 | VIIV Healthcare UK (No.5) Limited | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9273067B2 (en) | 2014-02-19 | 2016-03-01 | Bristol-Myers Squibb Company | Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication |
| US9975906B2 (en) | 2014-05-16 | 2018-05-22 | Shionogi & Co., Ltd. | Tricyclic heterocycle derivatives having HIV replication inhibitory effect |
| KR101592370B1 (ko) * | 2014-06-09 | 2016-02-11 | 한국화학연구원 | 신규한 피롤로피리딘 유도체 및 이의 hiv 저해제로서의 용도 |
| CN104478911A (zh) * | 2014-12-19 | 2015-04-01 | 成都安斯利生物医药有限公司 | 一种制备3-三氟甲基吡咯硼酸的方法 |
| TWI700284B (zh) | 2015-05-29 | 2020-08-01 | 日商塩野義製藥股份有限公司 | 具有ｈｉｖ複製抑制作用之含氮３環性衍生物 |
| PL3604303T3 (pl) | 2017-03-24 | 2023-04-11 | St Pharm Co., Ltd. | Nowa pochodna pirolopirydyny, sposób jej wytwarzania oraz jej zastosowanie |
| CN110831945B (zh) | 2017-03-29 | 2023-08-08 | 赛特温治疗公司 | 用于治疗疼痛的11,13-修饰的石房蛤毒素类化合物 |
| JP7096686B2 (ja) * | 2017-03-30 | 2022-07-06 | 住友化学株式会社 | アミノ基を有する有機リチウム化合物およびその中間体の製造方法、並びに有機リチウム化合物を用いた共役ジエン系重合体の製造方法 |
| CN114746424B (zh) | 2020-01-10 | 2023-06-16 | 江苏恒瑞医药股份有限公司 | 三环四氢异喹啉类衍生物、其制备方法及其在医药上的应用 |
| KR102909106B1 (ko) * | 2020-08-20 | 2026-01-07 | 에스티팜 주식회사 | 피롤로피리딘 유도체 및 이들의 용도 |
| EP4276101B1 (en) | 2021-01-11 | 2026-03-04 | ST Pharm Co., Ltd. | Pyrrolopyridine derivative preparation method |
| WO2025159587A1 (ko) * | 2024-01-25 | 2025-07-31 | 에스티팜 주식회사 | 헤테로아릴 화합물 및 이의 용도 |
| CN119462437B (zh) * | 2024-10-30 | 2025-10-10 | 中船(邯郸)派瑞特种气体股份有限公司 | 一种三氟甲磺酸三氟乙酯的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2564356A1 (en) * | 2004-04-26 | 2005-11-03 | Pfizer Inc. | Pyrrolopyridine derivatives and their use as hiv-integrase inhibitors |
| DE102004060659A1 (de) * | 2004-12-15 | 2006-07-06 | Lanxess Deutschland Gmbh | Neue substituierte 1H-Pyrrolo[2,3-b]pyridine und deren Herstellung |
| US7939545B2 (en) * | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| GB0710528D0 (en) * | 2007-06-01 | 2007-07-11 | Glaxo Group Ltd | Novel compounds |
| ES2402322T3 (es) * | 2007-11-15 | 2013-04-30 | Gilead Sciences, Inc. | Inhibidores de la replicación del virus de la inmunodeficiencia humana |
| EA019259B1 (ru) * | 2007-11-16 | 2014-02-28 | Джилид Сайенсиз, Инк. | Ингибиторы репликации вируса иммунодефицита человека |
| ES2463720T3 (es) * | 2007-11-16 | 2014-05-29 | Gilead Sciences, Inc. | Inhibidores de la replicación del virus de inmunodeficiencia humana |
| GB0908394D0 (en) * | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
| US8338441B2 (en) * | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| WO2012102985A1 (en) * | 2011-01-24 | 2012-08-02 | Glaxosmithkline Llc | Isoquinoline compounds and methods for treating hiv |
| WO2013012649A1 (en) * | 2011-07-15 | 2013-01-24 | Glaxosmithkline Llc | Azaindole compounds and methods for treating hiv |
-
2012
- 2012-11-15 WO PCT/KR2012/009689 patent/WO2013073875A1/ko not_active Ceased
- 2012-11-15 PT PT128491404T patent/PT2781519T/pt unknown
- 2012-11-15 JP JP2014542241A patent/JP5893156B2/ja active Active
- 2012-11-15 ES ES12849140T patent/ES2760981T3/es active Active
- 2012-11-15 CN CN201280066270.1A patent/CN104066732B/zh active Active
- 2012-11-15 KR KR1020120129805A patent/KR101467477B1/ko active Active
- 2012-11-15 PL PL12849140T patent/PL2781519T3/pl unknown
- 2012-11-15 DK DK12849140.4T patent/DK2781519T3/da active
- 2012-11-15 HU HUE12849140A patent/HUE046795T2/hu unknown
- 2012-11-15 EP EP12849140.4A patent/EP2781519B1/en active Active
-
2014
- 2014-05-15 US US14/278,955 patent/US9499537B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9499537B2 (en) | 2016-11-22 |
| JP5893156B2 (ja) | 2016-03-23 |
| US20140249162A1 (en) | 2014-09-04 |
| ES2760981T3 (es) | 2020-05-18 |
| KR101467477B1 (ko) | 2014-12-02 |
| HUE046795T2 (hu) | 2020-03-30 |
| CN104066732A (zh) | 2014-09-24 |
| CN104066732B (zh) | 2016-04-13 |
| EP2781519A4 (en) | 2015-06-24 |
| DK2781519T3 (da) | 2019-12-16 |
| JP2014533298A (ja) | 2014-12-11 |
| WO2013073875A1 (ko) | 2013-05-23 |
| PT2781519T (pt) | 2019-12-17 |
| KR20130054211A (ko) | 2013-05-24 |
| EP2781519A1 (en) | 2014-09-24 |
| EP2781519B1 (en) | 2019-10-30 |
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