PL2790712T3 - Podpopulacja ludzkich monocytów do leczenia uszkodzenia ośrodkowego układu nerwowego - Google Patents

Podpopulacja ludzkich monocytów do leczenia uszkodzenia ośrodkowego układu nerwowego

Info

Publication number
PL2790712T3
PL2790712T3 PL12858248T PL12858248T PL2790712T3 PL 2790712 T3 PL2790712 T3 PL 2790712T3 PL 12858248 T PL12858248 T PL 12858248T PL 12858248 T PL12858248 T PL 12858248T PL 2790712 T3 PL2790712 T3 PL 2790712T3
Authority
PL
Poland
Prior art keywords
subpopulation
treatment
nervous system
central nervous
human monocytes
Prior art date
Application number
PL12858248T
Other languages
English (en)
Inventor
Michal Eisenbach-Schwartz
Ester Yoles
Ravid Shechter
Omer Miller
Original Assignee
Yeda Research And Development Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research And Development Co. Ltd. filed Critical Yeda Research And Development Co. Ltd.
Publication of PL2790712T3 publication Critical patent/PL2790712T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/17—Monocytes; Macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/414—Nervous system antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL12858248T 2011-12-14 2012-12-13 Podpopulacja ludzkich monocytów do leczenia uszkodzenia ośrodkowego układu nerwowego PL2790712T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161570593P 2011-12-14 2011-12-14

Publications (1)

Publication Number Publication Date
PL2790712T3 true PL2790712T3 (pl) 2017-04-28

Family

ID=48611950

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12858248T PL2790712T3 (pl) 2011-12-14 2012-12-13 Podpopulacja ludzkich monocytów do leczenia uszkodzenia ośrodkowego układu nerwowego

Country Status (15)

Country Link
US (1) US9314483B2 (pl)
EP (1) EP2790712B1 (pl)
JP (1) JP6148679B2 (pl)
KR (1) KR20140107439A (pl)
CN (1) CN104159590A (pl)
AU (2) AU2012354057B2 (pl)
BR (1) BR112014014560A8 (pl)
DK (1) DK2790712T3 (pl)
ES (1) ES2604356T3 (pl)
HU (1) HUE032096T2 (pl)
IN (1) IN2014MN01420A (pl)
MX (1) MX358589B (pl)
PL (1) PL2790712T3 (pl)
PT (1) PT2790712T (pl)
WO (1) WO2013088441A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3226971B2 (ja) 1992-08-04 2001-11-12 栗田工業株式会社 イオン交換装置の採水−再生サイクル制御装置
ES2786253T3 (es) 2013-03-14 2020-10-09 Immusoft Corp Métodos para la diferenciación y transducción in vitro de células b de memoria con vectores virales pseudotipados vsv-g
BR112015029299A2 (pt) * 2013-05-22 2017-07-25 Yeda Res & Dev subpopulação de monócitos humanos para tratamento de doenças e distúrbios oculares
EP4177336A1 (en) * 2014-12-19 2023-05-10 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
WO2017096246A1 (en) * 2015-12-03 2017-06-08 Temple University-Of The Commonwealth System Of Higher Education Modulation of nad+ and nad+ metabolic pathways for treatment of disease
US20220146534A1 (en) * 2019-01-16 2022-05-12 Yeda Research And Development, Co., Ltd. Biomarkers for CNS Disease Modification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800812A (en) 1995-09-15 1998-09-01 Yeda Research And Development Co. Ltd. Methods of use of mononuclear phagocytes to promote axonal regeneration
WO1998005795A1 (en) * 1996-08-02 1998-02-12 The Center For Blood Research, Inc. Enrichment of dendritic cells from blood
US6267995B1 (en) 1999-03-03 2001-07-31 Pure World Botanicals, Inc. Extract of Lepidium meyenii roots for pharmaceutical applications
AU2002353465B2 (en) 2001-11-21 2008-10-16 Yeda Research And Development Co. Ltd. Process for the manufacture of human mononuclear phagocytic leukocytes
JP2011515470A (ja) * 2008-03-28 2011-05-19 ステムサイト インコーポレーテッド 臍帯血細胞を用いた脳損傷の処置
BR112015029299A2 (pt) * 2013-05-22 2017-07-25 Yeda Res & Dev subpopulação de monócitos humanos para tratamento de doenças e distúrbios oculares

Also Published As

Publication number Publication date
HUE032096T2 (en) 2017-09-28
MX2014007188A (es) 2015-09-22
JP2015501835A (ja) 2015-01-19
PT2790712T (pt) 2016-12-02
KR20140107439A (ko) 2014-09-04
ES2604356T3 (es) 2017-03-06
MX358589B (es) 2018-08-27
BR112014014560A8 (pt) 2017-07-04
WO2013088441A1 (en) 2013-06-20
EP2790712B1 (en) 2016-08-31
EP2790712A1 (en) 2014-10-22
DK2790712T3 (en) 2016-12-19
AU2012354057A1 (en) 2014-07-31
EP2790712A4 (en) 2015-06-24
US20140363411A1 (en) 2014-12-11
JP6148679B2 (ja) 2017-06-14
US9314483B2 (en) 2016-04-19
CN104159590A (zh) 2014-11-19
IN2014MN01420A (pl) 2015-04-03
BR112014014560A2 (pt) 2017-06-13
AU2012354057B2 (en) 2017-08-03
AU2017254830A1 (en) 2017-11-16

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