PL2854870T3 - Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego - Google Patents

Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego

Info

Publication number
PL2854870T3
PL2854870T3 PL13725620T PL13725620T PL2854870T3 PL 2854870 T3 PL2854870 T3 PL 2854870T3 PL 13725620 T PL13725620 T PL 13725620T PL 13725620 T PL13725620 T PL 13725620T PL 2854870 T3 PL2854870 T3 PL 2854870T3
Authority
PL
Poland
Prior art keywords
lead
production
medical use
medical
Prior art date
Application number
PL13725620T
Other languages
English (en)
Inventor
Julien Torgue
Patrick Maquaire
John Young
Gilbert Andreoletti
Patrick Bourdet
Original Assignee
Orano Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orano Med filed Critical Orano Med
Publication of PL2854870T3 publication Critical patent/PL2854870T3/pl

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005—Isotope delivery systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B13/00—Obtaining lead
    • C22B13/02—Obtaining lead by dry processes
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B13/00—Obtaining lead
    • C22B13/06—Refining
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C11/00—Alloys based on lead
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N2030/067—Preparation by reaction, e.g. derivatising the sample
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001—Recovery of specific isotopes from irradiated targets
    • G21G2001/0094—Other isotopes not provided for in the groups listed above
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00—Radioactive sources
    • G21G4/04—Radioactive sources other than neutron sources
    • G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
PL13725620T 2012-05-24 2013-05-23 Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego PL2854870T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1254798A FR2990956B1 (fr) 2012-05-24 2012-05-24 Procede et appareil pour la production de plomb 212 a usage medical
PCT/EP2013/060672 WO2013174949A1 (en) 2012-05-24 2013-05-23 Method and apparatus for the production of lead 212 for medical use
EP13725620.2A EP2854870B1 (en) 2012-05-24 2013-05-23 Method and apparatus for the production of lead 212 for medical use

Publications (1)

Publication Number Publication Date
PL2854870T3 true PL2854870T3 (pl) 2019-01-31

Family

ID=48536828

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13725620T PL2854870T3 (pl) 2012-05-24 2013-05-23 Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego

Country Status (12)

Country Link
US (2) US10020086B2 (pl)
EP (1) EP2854870B1 (pl)
JP (1) JP6392210B2 (pl)
AU (1) AU2013265268B2 (pl)
DK (1) DK2854870T3 (pl)
ES (1) ES2683398T3 (pl)
FR (1) FR2990956B1 (pl)
PL (1) PL2854870T3 (pl)
PT (1) PT2854870T (pl)
SI (1) SI2854870T1 (pl)
TR (1) TR201811310T4 (pl)
WO (1) WO2013174949A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015247689B2 (en) * 2014-04-15 2019-10-10 Lantheus Medical Imaging, Inc. Methods and devices for isolating lead 203
CN104528653B (zh) * 2015-01-26 2017-01-11 中国工程物理研究院核物理与化学研究所 一种立式Na131I干馏生产装置
CN104528652B (zh) * 2015-01-26 2016-04-06 中国工程物理研究院核物理与化学研究所 直立式Na131I干馏生产装置
WO2016128022A1 (en) * 2015-02-09 2016-08-18 Areva Gmbh Radionuclide generation system
US9433690B1 (en) * 2015-02-26 2016-09-06 Sciencons AS Radiopharmaceutical solutions with advantageous properties
ES2688061T3 (es) 2015-11-30 2018-10-30 Orano Med Nuevo procedimiento y aparato para la producción de radionúclidos de alta pureza
FR3086186B1 (fr) 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
FR3088768B1 (fr) * 2018-11-15 2020-11-20 Orano Med Procede de transfert d'un radioisotope entre deux phases stationnaires contenues dans deux colonnes de chromatographie
FR3088769B1 (fr) 2018-11-15 2020-12-25 Orano Med Procede de preparation d'au moins un generateur a haute teneur en radium-228
EP3800648A1 (en) * 2019-10-04 2021-04-07 Sck Cen Methods and systems for the production of isotopes
CN114902350A (zh) * 2019-12-05 2022-08-12 塞控斯公司 生产高纯度212Pb
EP4385045B1 (en) 2021-08-11 2025-10-01 Nrg Pallas B.V. System and method of the production and isolation of charged radionuclides
CN118451221A (zh) 2021-08-23 2024-08-06 安德万细胞同位素有限公司 用于产生放射性同位素的材料和方法
US11383204B1 (en) 2021-09-08 2022-07-12 Potentgen Nükleer Tip Biyoteknoloji Klinik Araştirma Ve Danişmanlik Anonim Şirket Method for production of lead-212 isotope
EP4532005A4 (en) * 2023-08-15 2025-10-22 Perspective Therapeutics Inc LEAD GENERATION SYSTEMS AND METHODS

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663129A (en) * 1985-01-30 1987-05-05 The United States Of America As Represented By The United States Department Of Energy Isotopic generator for bismuth-212 and lead-212 from radium
US5038046A (en) * 1990-07-10 1991-08-06 Biotechnetics Method and generator for producing radioactive lead-212
WO1998008481A2 (en) * 1996-08-26 1998-03-05 Arch Development Corporation PROCESS AND APPARATUS FOR THE PRODUCTION OF Bi-212 AND A USE THEREOF
ATE527038T1 (de) * 2001-06-22 2011-10-15 Pg Res Foundation Inc Automatisiertes system und verfahren zur trennung von radionukliden
DE60228960D1 (de) * 2001-06-22 2008-10-30 Pg Res Foundation Inc Kompakte automatisierte vorrichtung zur trennung von radionukliden
US6998052B2 (en) * 2002-04-12 2006-02-14 Pg Research Foundation Multicolumn selectivity inversion generator for production of ultrapure radionuclides
US9283521B2 (en) * 2002-06-14 2016-03-15 Parker-Hannifin Corporation Single-use manifold and sensors for automated, aseptic transfer of solutions in bioprocessing applications
WO2005079867A2 (en) * 2004-02-20 2005-09-01 Algeta As Alpha-emitting hydroxyapatite particles
GB2436508C (en) * 2005-01-14 2011-01-26 Europ Organisation For Nuclear Res Cern Method for production of radioisotope preparationsand their use in life science, research, medical application and industry.
US20070009409A1 (en) * 2005-07-11 2007-01-11 Hariprasad Gali 212Bi or 213Bi Generator from supported parent isotope
US7838844B2 (en) * 2005-10-03 2010-11-23 Mallinckrodt Inc. Radiopharmaceutical system and method utilizing radio-frequency identification tags
US7700926B2 (en) * 2006-01-12 2010-04-20 Draximage General Partnership Systems and methods for radioisotope generation
US7586102B2 (en) * 2006-08-14 2009-09-08 Board Of Regents The University Of Texas System Automated system for formulating radiopharmaceuticals
US9326742B2 (en) * 2007-01-01 2016-05-03 Bayer Healthcare Llc Systems for integrated radiopharmaceutical generation, preparation, transportation and administration
AU2008243144A1 (en) * 2008-11-06 2010-05-20 Quark Technologies Australia Pty Ltd Improvements in Radiopharmaceutical Purification
US8435454B2 (en) * 2009-07-09 2013-05-07 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US8273300B2 (en) * 2009-07-09 2012-09-25 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US20120108858A1 (en) * 2010-10-28 2012-05-03 Maxim Kiselev Method and device for manufacturing of radiopharmaceuticals
CA2854820C (en) * 2011-12-08 2016-05-24 Nordion (Canada) Inc. Method of pre-treating an adsorbent for a chromatographic separation
US9299466B2 (en) * 2013-10-30 2016-03-29 NorthStar Medical Radioisotopes LLC System for processing and tracking radionuclides

Also Published As

Publication number Publication date
AU2013265268B2 (en) 2016-07-07
ES2683398T3 (es) 2018-09-26
EP2854870A1 (en) 2015-04-08
FR2990956A1 (fr) 2013-11-29
EP2854870B1 (en) 2018-05-16
FR2990956B1 (fr) 2014-07-04
AU2013265268A2 (en) 2016-06-30
WO2013174949A1 (en) 2013-11-28
US20180308600A1 (en) 2018-10-25
SI2854870T1 (sl) 2018-10-30
DK2854870T3 (en) 2018-08-06
US20150170776A1 (en) 2015-06-18
PT2854870T (pt) 2018-10-03
JP6392210B2 (ja) 2018-09-19
AU2013265268A1 (en) 2014-12-18
JP2015523555A (ja) 2015-08-13
US10020086B2 (en) 2018-07-10
US11037690B2 (en) 2021-06-15
TR201811310T4 (tr) 2018-08-27

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