PL2864781T3 - Sposób i układ do jakościowego lub ilościowego oznaczania składnika docelowego - Google Patents

Sposób i układ do jakościowego lub ilościowego oznaczania składnika docelowego

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Publication number
PL2864781T3
PL2864781T3 PL13807718T PL13807718T PL2864781T3 PL 2864781 T3 PL2864781 T3 PL 2864781T3 PL 13807718 T PL13807718 T PL 13807718T PL 13807718 T PL13807718 T PL 13807718T PL 2864781 T3 PL2864781 T3 PL 2864781T3
Authority
PL
Poland
Prior art keywords
quantitative
target component
qualitative determination
qualitative
determination
Prior art date
Application number
PL13807718T
Other languages
English (en)
Inventor
Martin Heller
Bent Overby
Niels Kristian Bau-Madsen
Original Assignee
Scandinavian Micro Biodevices Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scandinavian Micro Biodevices Aps filed Critical Scandinavian Micro Biodevices Aps
Publication of PL2864781T3 publication Critical patent/PL2864781T3/pl

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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Optics & Photonics (AREA)
  • Fluid Mechanics (AREA)
  • Materials Engineering (AREA)
  • Virology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
PL13807718T 2012-06-22 2013-06-21 Sposób i układ do jakościowego lub ilościowego oznaczania składnika docelowego PL2864781T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201270353 2012-06-22
EP13807718.5A EP2864781B1 (en) 2012-06-22 2013-06-21 A method and a system for quantitative or qualitative determination of a target component
PCT/DK2013/050208 WO2013189502A1 (en) 2012-06-22 2013-06-21 A method and a system for quantitative or qualitative determination of a target component

Publications (1)

Publication Number Publication Date
PL2864781T3 true PL2864781T3 (pl) 2018-05-30

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US (2) US10859571B2 (pl)
EP (1) EP2864781B1 (pl)
JP (1) JP6301322B2 (pl)
AU (1) AU2013279833B2 (pl)
BR (1) BR112014032304B1 (pl)
DK (1) DK2864781T3 (pl)
NZ (1) NZ703227A (pl)
PL (1) PL2864781T3 (pl)
WO (1) WO2013189502A1 (pl)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
CN111871476B (zh) 2014-06-18 2022-08-16 硕腾丹麦公司 微流控检测系统和微流控盒
US11262354B2 (en) * 2014-10-20 2022-03-01 Boston Scientific Scimed, Inc. Disposable sensor elements, systems, and related methods
JP6466775B2 (ja) * 2015-04-30 2019-02-06 シスメックス株式会社 検体分析カートリッジを用いた検体分析方法、検体分析カートリッジ、および、検体分析装置
TWI789343B (zh) 2016-02-01 2023-01-11 丹麥商碩騰丹麥有限公司 微流體分析系統、執行分析的微流體匣及方法
US10807093B2 (en) 2016-02-05 2020-10-20 Katholieke Universiteit Leuven Microfluidic systems
EP3439544B1 (en) 2016-06-15 2024-05-15 Regents of the University of Minnesota Gas sampling catheters
CN107583675B (zh) * 2016-07-06 2023-04-14 广州好芝生物科技有限公司 一种流控机构及含有该机构的系统
CN109862829A (zh) 2016-10-21 2019-06-07 波士顿科学国际有限公司 气体采样装置
WO2018140719A1 (en) * 2017-01-26 2018-08-02 Confer Health, Inc. Magnetic particle-based immunoassay and methods of using the same
WO2018213564A1 (en) 2017-05-19 2018-11-22 Cardiac Pacemakers, Inc. Systems and methods for assessing the health status of a patient
US10852264B2 (en) 2017-07-18 2020-12-01 Boston Scientific Scimed, Inc. Systems and methods for analyte sensing in physiological gas samples
US11166636B2 (en) 2018-02-20 2021-11-09 Boston Scientific Scimed, Inc. Breath sampling mask and system
US11291997B2 (en) * 2018-08-02 2022-04-05 Colorado State University Research Foundation Rotary manifold for paper-based immunoassays
WO2020081834A1 (en) 2018-10-19 2020-04-23 Regents Of The University Of Minnesota Systems and methods for detecting a brain condition
EP3861329A1 (en) 2018-11-27 2021-08-11 Boston Scientific Scimed Inc. Systems and methods for detecting a health condition
CN113196047B (zh) 2018-12-18 2024-08-16 明尼苏达大学董事会 用于测量化学传感器元件的动力学响应的系统和方法
CN111366725A (zh) * 2018-12-26 2020-07-03 台达电子工业股份有限公司 增强检测信号的检测方法、装置及试片
US20200206735A1 (en) * 2018-12-26 2020-07-02 Delta Electronics, Inc. Detection method, device and cartridge for enhancing detection signal intensity
CN113747836A (zh) 2019-04-29 2021-12-03 明尼苏达大学董事会 用于评估和治疗出血及其他病症的系统和方法
EP4028758A2 (en) 2019-09-10 2022-07-20 Boston Scientific Scimed Inc. Gas measurement device and method
KR20220100883A (ko) * 2019-11-15 2022-07-18 에프. 호프만-라 로슈 아게 환자 샘플의 질량분석법 측정을 위한 베타-락탐 항생제의 유도체화
US12613212B2 (en) 2020-05-01 2026-04-28 Regents Of The University Of Minnesota Non-invasive bladder cancer detection system via liquid and gaseous phase analysis
WO2021252856A1 (en) 2020-06-11 2021-12-16 New York University Devices. methods, and applications for recirculation of fluids in microfluidic channels
WO2022029732A1 (en) * 2020-08-07 2022-02-10 Vital Biosciences Inc. Kinetic modulation for magnetic analyte detection
US20240295549A1 (en) * 2020-08-07 2024-09-05 Vital Biosciences Inc. Multiplexed analyte detection
US12480907B2 (en) 2021-04-16 2025-11-25 Regents Of The University Of Minnesota Systems utilizing graphene varactor hysteresis effects for sample characterization
CN115308200B (zh) * 2022-10-12 2022-12-13 东营钧辰石油设备有限责任公司 一种采用醋酸铅纸法密闭式气体检测仪

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2063385B (en) * 1979-11-23 1983-06-22 Cross Mfg Co 1938 Ltd Gas seals
US4347312A (en) 1980-03-20 1982-08-31 Research Triangle Institute Detection of antibiotics in milk
FI842992A0 (fi) 1984-07-26 1984-07-26 Labsystems Oy Immunologiskt definitionsfoerfarande.
JP2001518624A (ja) * 1997-09-26 2001-10-16 ユニバーシティ・オブ・ワシントン 同時の粒子分離および化学反応
JP4404489B2 (ja) * 1998-09-18 2010-01-27 マサチューセッツ インスティテュート オブ テクノロジー 水溶性蛍光半導体ナノ結晶
EP1116036B1 (en) 1998-09-18 2004-08-11 Massachusetts Institute Of Technology Water-soluble fluorescent semiconductor nanocrystals
US6498497B1 (en) * 1998-10-14 2002-12-24 Caliper Technologies Corp. Microfluidic controller and detector system with self-calibration
US6565727B1 (en) * 1999-01-25 2003-05-20 Nanolytics, Inc. Actuators for microfluidics without moving parts
US6562581B2 (en) * 2001-08-31 2003-05-13 Portascience Method for quantitative determination of glycated hemoglobin
US7314763B2 (en) * 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US6872450B2 (en) * 2002-10-23 2005-03-29 Evident Technologies Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same
US20050226779A1 (en) * 2003-09-19 2005-10-13 Oldham Mark F Vacuum assist for a microplate
US7787923B2 (en) * 2003-11-26 2010-08-31 Becton, Dickinson And Company Fiber optic device for sensing analytes and method of making same
US20080032420A1 (en) * 2004-03-30 2008-02-07 Lambert James L Surface Enhanced Raman Scattering and Multiplexed Diagnostic Assays
US7521226B2 (en) * 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
EP1827693B1 (en) 2004-12-09 2010-03-24 Scandinavian Micro Biodevices ApS A micro fluidic device and methods for producing a micro fluidic device
WO2007092713A2 (en) * 2006-02-02 2007-08-16 Trustees Of The University Of Pennsylvania Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease
DK3088083T3 (en) * 2006-03-24 2018-11-26 Handylab Inc Method of carrying out PCR down a multi-track cartridge
US8492168B2 (en) * 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US7498177B2 (en) 2006-04-24 2009-03-03 Jesus Martinez De La Fuente Quantum dots and their uses
EP2049902A4 (en) * 2006-07-28 2010-09-01 Biosite Inc DEVICES AND METHODS FOR PERFORMING BINDING TESTS WITH RECEIVERS USING MAGNETIC PARTICLES
KR100872596B1 (ko) * 2006-11-24 2008-12-08 연세대학교 산학협력단 발광 다이오드와 광섬유 다발과의 결합구조와 이를 위한커넥터
US8586385B2 (en) * 2006-12-28 2013-11-19 Intel Corporation Method and device for biomolecule preparation and detection using magnetic array
US20080217254A1 (en) 2007-03-05 2008-09-11 Anderson N Leigh Magnetic Bead Trap and Mass Spectrometer Interface
JP2009019971A (ja) 2007-07-11 2009-01-29 Sumitomo Electric Ind Ltd マイクロ化学用光分析チップおよびマイクロ化学光分析システム
WO2009064490A2 (en) 2007-11-14 2009-05-22 The State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of Oregon State University Microchannel structures having bonded layers including height control features
EP2214824A4 (en) * 2007-11-28 2015-08-19 Smart Tube Inc DEVICES, SYSTEMS AND METHODS FOR DETECTING, STIMULATING, STABILIZING AND ANALYZING A BIOLOGICAL SAMPLE
JP4683066B2 (ja) * 2008-04-14 2011-05-11 コニカミノルタホールディングス株式会社 液体混合機構
US20090270269A1 (en) 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
US8618508B2 (en) * 2008-09-25 2013-12-31 Koninklijke Philips N.V. Detection system and method
WO2010042242A1 (en) 2008-10-10 2010-04-15 Rutgers, The State University Of New Jersey Methods and related devices for continuous sensing utilizing magnetic beads
EP2346607A2 (en) * 2008-10-10 2011-07-27 Cnrs-Dae Microfluidic integrated device for sample processing
US8585627B2 (en) * 2008-12-04 2013-11-19 The Invention Science Fund I, Llc Systems, devices, and methods including catheters configured to monitor biofilm formation having biofilm spectral information configured as a data structure
WO2010141105A2 (en) 2009-01-23 2010-12-09 Bae Systems Information And Electronic Systems Integration Inc. Quantum dot-sensory array for biological recognition
TWI400446B (zh) 2009-03-20 2013-07-01 Univ Nat Cheng Kung 免疫分析晶片
JP5451236B2 (ja) 2009-07-31 2014-03-26 富士フイルム株式会社 検出方法、および該検出方法に用いられる磁性体含有誘電体粒子
WO2011026030A1 (en) 2009-08-31 2011-03-03 Mbio Diagnostics Corporation Integrated sample preparation and analyte detection
WO2012016107A1 (en) 2010-07-30 2012-02-02 Sdix Methods and kits for detection of salmonella enteritidis and related serovars
GB201014805D0 (en) * 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
US20120275929A1 (en) * 2011-04-27 2012-11-01 Aptina Imaging Corporation Ferrofluid control and sample collection for microfluidic application

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