PL2922530T3 - Formulacje octanu kaspofunginy - Google Patents

Formulacje octanu kaspofunginy

Info

Publication number
PL2922530T3
PL2922530T3 PL12810519T PL12810519T PL2922530T3 PL 2922530 T3 PL2922530 T3 PL 2922530T3 PL 12810519 T PL12810519 T PL 12810519T PL 12810519 T PL12810519 T PL 12810519T PL 2922530 T3 PL2922530 T3 PL 2922530T3
Authority
PL
Poland
Prior art keywords
caspofungin acetate
acetate formulations
formulations
caspofungin
acetate
Prior art date
Application number
PL12810519T
Other languages
English (en)
Inventor
Zhi-Qiang Jiang
Arunya Usayapant
David Bowman
Keith Kwok
Joel Peterson
Original Assignee
Fresenius Kabi Usa, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Usa, Llc filed Critical Fresenius Kabi Usa, Llc
Publication of PL2922530T3 publication Critical patent/PL2922530T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL12810519T 2012-11-20 2012-12-21 Formulacje octanu kaspofunginy PL2922530T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261728406P 2012-11-20 2012-11-20

Publications (1)

Publication Number Publication Date
PL2922530T3 true PL2922530T3 (pl) 2017-04-28

Family

ID=47505366

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12810519T PL2922530T3 (pl) 2012-11-20 2012-12-21 Formulacje octanu kaspofunginy

Country Status (14)

Country Link
US (4) US9636407B2 (pl)
EP (1) EP2922530B1 (pl)
CA (1) CA2888625A1 (pl)
CY (1) CY1120016T1 (pl)
DK (1) DK2922530T3 (pl)
ES (1) ES2607646T3 (pl)
HR (1) HRP20161703T1 (pl)
HU (1) HUE032392T2 (pl)
LT (1) LT2922530T (pl)
PL (1) PL2922530T3 (pl)
PT (1) PT2922530T (pl)
SI (1) SI2922530T1 (pl)
SM (1) SMT201600452B (pl)
WO (1) WO2014081443A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20161703T1 (hr) * 2012-11-20 2017-03-10 Fresenius Kabi Usa, Llc Formulacije kaspofungin acetata
WO2017185030A1 (en) * 2016-04-22 2017-10-26 Fresenius Kabi Usa, Llc Caspofungin formulation with low impurities
WO2019148282A1 (en) * 2018-02-01 2019-08-08 The Royal Institution For The Advancement Of Learning/Mcgill University Formulations for improving the delivery of hydrophobic agents
WO2019157453A1 (en) 2018-02-12 2019-08-15 Trilogy Therapeutics, Inc. Caspofungin compositions for inhalation
EP3628683A1 (en) * 2018-09-28 2020-04-01 Zealand Pharma A/S Formulations of glucagon-like-peptide-2 (glp-2) analogues
CN109758426B (zh) * 2019-01-24 2021-04-27 四川制药制剂有限公司 一种注射用醋酸卡泊芬净药物组合物及其制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
WO1996008266A1 (en) 1994-09-16 1996-03-21 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516756A (en) 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
US5952300A (en) * 1996-04-19 1999-09-14 Merck & Co., Inc. Antifungal compositions
USRE38984E1 (en) 1996-09-12 2006-02-14 Merck & Co., Inc. Antifungal combination therapy
US5936062A (en) 1997-06-12 1999-08-10 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
CN100448482C (zh) 1999-05-31 2009-01-07 三菱化学株式会社 Hgf冻干制剂
ATE267582T1 (de) 2000-01-20 2004-06-15 Basilea Pharmaceutica Ag Nasal verabreichbare cyclische antimykotische peptidzusammensetzungen
US6803046B2 (en) 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
US8158152B2 (en) 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
ES2401299T5 (es) 2006-07-26 2016-04-06 Sandoz Ag Formulaciones de caspofungina
TW200826957A (en) 2006-10-16 2008-07-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Purification processes for echinocandin-type compounds
CA2692053A1 (en) 2007-06-26 2008-12-31 Merck Sharp & Dohme Corp. Lyophilized anti-fungal composition
WO2009006301A2 (en) 2007-06-29 2009-01-08 Battelle Memorial Institute Protein stabilization
CN102026621A (zh) 2008-05-15 2011-04-20 巴克斯特国际公司 稳定的药物制剂
WO2009142761A1 (en) 2008-05-21 2009-11-26 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Caspofungin bo free of caspofungin co
US20090324635A1 (en) 2008-06-25 2009-12-31 Ferenc Korodi Caspofungin free of caspofungin impurity A
WO2010008493A2 (en) 2008-06-25 2010-01-21 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Processes for preparing high purity aza cyclohexapeptides
GB0817121D0 (en) 2008-09-18 2008-10-29 Univ St Andrews Anti-fungal therapy
TW201024322A (en) 2008-12-31 2010-07-01 Chunghwa Chemical Synthesis & Biotech Co Ltd Preparation method for nitrogen containing heterocyclic hexapeptide with high conversion rate
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
CN102947327B (zh) 2010-03-29 2017-06-13 中化帝斯曼制药有限公司荷兰公司 卡泊芬净中间体的纯化
RU2013114993A (ru) 2010-09-20 2014-10-27 Кселлия Фармасьютикалз Апс Композиция каспофунгина
WO2012041801A1 (en) 2010-09-28 2012-04-05 Dsm Sinochem Pharmaceuticals Netherlands B.V. Method for isolating a cyclohexapeptide
CA2826086A1 (en) 2011-01-03 2012-07-12 Biocon Limited Process for preparation of caspofungin acetate and intermediates
CN102166186A (zh) 2011-04-18 2011-08-31 深圳市健元医药科技有限公司 一种更加稳定的氮杂环己肽类制剂
CN102746384B (zh) 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
RU2592280C2 (ru) 2011-04-28 2016-07-20 Юнитрис Биофарма Ко., Лтд Промежуточное соединение для синтеза каспофунгина и способ его получения
HRP20161703T1 (hr) * 2012-11-20 2017-03-10 Fresenius Kabi Usa, Llc Formulacije kaspofungin acetata
CN105164146B (zh) 2013-05-02 2019-06-28 灿盛制药有限公司荷兰公司 分离卡泊芬净的方法
US9556233B2 (en) 2013-09-11 2017-01-31 Dsm Sinochem Pharmaceuticals Netherlands B.V. Cyclohexapeptide

Also Published As

Publication number Publication date
US20160310597A1 (en) 2016-10-27
US20190105392A1 (en) 2019-04-11
HUE032392T2 (en) 2017-09-28
LT2922530T (lt) 2017-01-25
HK1215668A1 (en) 2016-09-09
EP2922530A1 (en) 2015-09-30
ES2607646T3 (es) 2017-04-03
SMT201600452B (it) 2017-01-10
US20140142032A1 (en) 2014-05-22
HRP20161703T1 (hr) 2017-03-10
EP2922530B1 (en) 2016-09-14
PT2922530T (pt) 2016-12-22
WO2014081443A1 (en) 2014-05-30
CY1120016T1 (el) 2018-12-12
US20170296667A1 (en) 2017-10-19
US9636407B2 (en) 2017-05-02
SI2922530T1 (sl) 2017-04-26
CA2888625A1 (en) 2014-05-30
DK2922530T3 (en) 2017-01-09

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