PL2931922T3 - Personalizowane biomarkery nowotworu - Google Patents

Personalizowane biomarkery nowotworu

Info

Publication number
PL2931922T3
PL2931922T3 PL13863107T PL13863107T PL2931922T3 PL 2931922 T3 PL2931922 T3 PL 2931922T3 PL 13863107 T PL13863107 T PL 13863107T PL 13863107 T PL13863107 T PL 13863107T PL 2931922 T3 PL2931922 T3 PL 2931922T3
Authority
PL
Poland
Prior art keywords
cancer
personalized biomarkers
biomarkers
personalized
Prior art date
Application number
PL13863107T
Other languages
English (en)
Inventor
Ekkehard Schütz
Julia Beck
Howard Urnovitz
Original Assignee
Chronix Biomedical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chronix Biomedical filed Critical Chronix Biomedical
Publication of PL2931922T3 publication Critical patent/PL2931922T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL13863107T 2012-12-14 2013-12-13 Personalizowane biomarkery nowotworu PL2931922T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737626P 2012-12-14 2012-12-14
EP13863107.2A EP2931922B1 (en) 2012-12-14 2013-12-13 Personalized biomarkers for cancer
PCT/US2013/075015 WO2014093825A1 (en) 2012-12-14 2013-12-13 Personalized biomarkers for cancer

Publications (1)

Publication Number Publication Date
PL2931922T3 true PL2931922T3 (pl) 2019-04-30

Family

ID=50934991

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13863107T PL2931922T3 (pl) 2012-12-14 2013-12-13 Personalizowane biomarkery nowotworu

Country Status (5)

Country Link
US (1) US9909186B2 (pl)
EP (1) EP2931922B1 (pl)
ES (1) ES2703764T3 (pl)
PL (1) PL2931922T3 (pl)
WO (1) WO2014093825A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105531375B (zh) 2012-12-10 2020-03-03 分析生物科学有限公司 靶向基因组分析的方法
CN105190656B (zh) 2013-01-17 2018-01-16 佩索纳里斯公司 用于遗传分析的方法和系统
GB2534067B (en) 2013-08-30 2021-07-21 Personalis Inc Methods and systems for genomic analysis
GB2535066A (en) 2013-10-03 2016-08-10 Personalis Inc Methods for analyzing genotypes
US20160053301A1 (en) 2014-08-22 2016-02-25 Clearfork Bioscience, Inc. Methods for quantitative genetic analysis of cell free dna
JP7441584B6 (ja) * 2014-08-22 2024-03-15 レゾリューション バイオサイエンス, インコーポレイテッド 無細胞DNA(cfDNA)の定量的遺伝子解析のための方法
US10125399B2 (en) 2014-10-30 2018-11-13 Personalis, Inc. Methods for using mosaicism in nucleic acids sampled distal to their origin
US20180305757A1 (en) * 2015-10-16 2018-10-25 The Regents Of The University Of California Repetitive Element (RE)-based Genome Analysis and Dynamic Genetics Surveillance Systems
EP3889257A1 (en) 2015-11-11 2021-10-06 Resolution Bioscience, Inc. High efficiency construction of dna libraries
US11299783B2 (en) 2016-05-27 2022-04-12 Personalis, Inc. Methods and systems for genetic analysis
KR102505122B1 (ko) 2016-08-25 2023-03-08 레졸루션 바이오사이언스, 인크. Dna 샘플 중 게놈 카피 변화의 검출을 위한 방법
WO2018094031A1 (en) * 2016-11-16 2018-05-24 Progenity, Inc. Multimodal assay for detecting nucleic acid aberrations
US11814750B2 (en) 2018-05-31 2023-11-14 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
US10801064B2 (en) 2018-05-31 2020-10-13 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
WO2020168239A1 (en) * 2019-02-15 2020-08-20 Takara Bio Usa, Inc. Methods of preparing and analyzing nucleic acid libraries
CN109825583B (zh) * 2019-03-01 2021-08-17 清华大学 人重复元件dna甲基化作为肝癌早期诊断的标记物及其应用
JP7470787B2 (ja) 2019-11-05 2024-04-18 パーソナリス,インコーポレイティド 単一試料からの腫瘍純度の推定
US20230357854A1 (en) * 2020-08-24 2023-11-09 Dana-Farber Cancer Institute, Inc. Enhanced sequencing following random dna ligation and repeat element amplification
WO2023059654A1 (en) 2021-10-05 2023-04-13 Personalis, Inc. Customized assays for personalized cancer monitoring
WO2025059176A1 (en) * 2023-09-15 2025-03-20 The Johns Hopkins University Assessing and treating cancer
WO2026006629A1 (en) 2024-06-27 2026-01-02 Personalis, Inc. System and method for management of compressed sequencing files

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955589A (en) 1991-12-24 1999-09-21 Isis Pharmaceuticals Inc. Gapped 2' modified oligonucleotides
YU187991A (sh) 1990-12-11 1994-09-09 Hoechst Aktiengesellschaft 3-(2)-amino-ali tiol-modifikovani, s fluorescentnom bojom vezani nukleozidi, nukleotidi i oligonukleotidi, postupak za njihovo dobijanje i njihova upotreba
US5652099A (en) 1992-02-12 1997-07-29 Conrad; Michael J. Probes comprising fluorescent nucleosides and uses thereof
US5446137B1 (en) 1993-12-09 1998-10-06 Behringwerke Ag Oligonucleotides containing 4'-substituted nucleotides
DE4415370A1 (de) 1994-05-02 1995-11-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
DE4438918A1 (de) 1994-11-04 1996-05-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
US5773649A (en) * 1996-06-10 1998-06-30 Centre De Recherche De L'hopital Sainte-Justine DNA markers to detect cancer cells expressing a mutator phenotype and method of diagnosis of cancer cells
JP4044142B2 (ja) * 1996-10-04 2008-02-06 ビー. アーノビッツ,ハワード 核酸の診断検出
DK0866071T3 (da) 1997-03-20 2005-01-17 Hoffmann La Roche Modificerede primere
USH2191H1 (en) * 2000-10-24 2007-06-05 Snp Consortium Identification and mapping of single nucleotide polymorphisms in the human genome
WO2007111937A1 (en) * 2006-03-23 2007-10-04 Applera Corporation Directed enrichment of genomic dna for high-throughput sequencing
WO2010117817A2 (en) * 2009-03-30 2010-10-14 Life Technologies Corporation Methods for generating target specific probes for solution based capture
CN102409048B (zh) * 2010-09-21 2013-10-23 深圳华大基因科技服务有限公司 一种基于高通量测序的dna标签文库构建方法
WO2012129008A1 (en) * 2011-03-18 2012-09-27 Baylor Research Institute Line-1 hypomethylation as a biomarker for early-onset colorectal cancer
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US20150275308A1 (en) * 2012-10-19 2015-10-01 Sequenta, Inc. Monitoring diffuse large b-cell lymphoma from peripheral blood samples

Also Published As

Publication number Publication date
WO2014093825A1 (en) 2014-06-19
US20160053328A1 (en) 2016-02-25
EP2931922A1 (en) 2015-10-21
US9909186B2 (en) 2018-03-06
ES2703764T3 (es) 2019-03-12
EP2931922B1 (en) 2018-10-17
EP2931922A4 (en) 2016-07-27

Similar Documents

Publication Publication Date Title
EP2825674A4 (en) BIOMARKER FOR THYROID CANCER
GB201213567D0 (en) Biomarkers
EP2931922A4 (en) PERSONALIZED BIOMARKERS FOR CANCER
ZA201503280B (en) Physical channel design for network-assisted d2d
PL2714926T3 (pl) Biomarkery raka płuca
IL237436A0 (en) A method for screening cancer
IL233803A0 (en) Monocyte biomarkers for cancer detection
PL2876447T3 (pl) Sposób wykrywania nowotworu
GB201211982D0 (en) Biomarker
EP2986326A4 (en) Methods for detecting cancer metastasis
EP2994545A4 (en) Dna methylation biomarkers for bladder cancer
EP2831270B8 (en) Biomarker for bladder cancer
LT3143972T (lt) Blauzdinio pėdos sąnario ortozė
EP2985605A4 (en) Method for detecting colon cancer
GB201322800D0 (en) Prostate cancer biomarkers
WO2015095862A3 (en) Microrna biomarkers for ovarian cancer
IL242551A (en) Expectation markers for cancer treatment
ZA201409006B (en) Diabetes biomarkers
EP3030906A4 (en) Biomarkers for ovarian cancer
GB201104556D0 (en) Biomarkers
GB201210565D0 (en) Biomarkers
EP3033617A4 (en) Biomarkers for prostate cancer
GB2510539B (en) Biomarkers of cancer
GB201306339D0 (en) Biomarkers for prognosis
ZA201504169B (en) Anti-adam28 antibody for treating cancer