PL2943460T3 - 6-chloro-3-(fenylo-d5)inden-1-on i jego zastosowanie - Google Patents
6-chloro-3-(fenylo-d5)inden-1-on i jego zastosowanieInfo
- Publication number
- PL2943460T3 PL2943460T3 PL13811511T PL13811511T PL2943460T3 PL 2943460 T3 PL2943460 T3 PL 2943460T3 PL 13811511 T PL13811511 T PL 13811511T PL 13811511 T PL13811511 T PL 13811511T PL 2943460 T3 PL2943460 T3 PL 2943460T3
- Authority
- PL
- Poland
- Prior art keywords
- inden
- chloro
- phenyl
- Prior art date
Links
- VBFPHOYPKVNWMJ-RALIUCGRSA-N 6-chloro-3-(2,3,4,5,6-pentadeuteriophenyl)inden-1-one Chemical compound [2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1C1=CC(=O)C2=CC(Cl)=CC=C12 VBFPHOYPKVNWMJ-RALIUCGRSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261739095P | 2012-12-19 | 2012-12-19 | |
| DKPA201200811 | 2012-12-19 | ||
| EP13811511.8A EP2943460B1 (en) | 2012-12-19 | 2013-12-19 | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof |
| PCT/EP2013/077314 WO2014096151A2 (en) | 2012-12-19 | 2013-12-19 | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2943460T3 true PL2943460T3 (pl) | 2020-06-29 |
Family
ID=59295365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13811511T PL2943460T3 (pl) | 2012-12-19 | 2013-12-19 | 6-chloro-3-(fenylo-d5)inden-1-on i jego zastosowanie |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9309165B2 (pl) |
| EP (1) | EP2943460B1 (pl) |
| JP (1) | JP6290921B2 (pl) |
| KR (1) | KR102212096B1 (pl) |
| CN (1) | CN104955796B (pl) |
| AR (1) | AR094054A1 (pl) |
| AU (1) | AU2013366693B2 (pl) |
| BR (1) | BR112015014384A2 (pl) |
| CA (1) | CA2893224C (pl) |
| CL (1) | CL2015001720A1 (pl) |
| CY (1) | CY1122715T1 (pl) |
| DK (1) | DK2943460T3 (pl) |
| HR (1) | HRP20200385T1 (pl) |
| IL (1) | IL239097A (pl) |
| LT (1) | LT2943460T (pl) |
| MX (1) | MX365707B (pl) |
| PL (1) | PL2943460T3 (pl) |
| PT (1) | PT2943460T (pl) |
| RS (1) | RS59982B1 (pl) |
| RU (1) | RU2681221C2 (pl) |
| SG (1) | SG11201504437SA (pl) |
| SI (1) | SI2943460T1 (pl) |
| SM (1) | SMT202000131T1 (pl) |
| WO (1) | WO2014096151A2 (pl) |
| ZA (1) | ZA201504405B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3135656T1 (sl) | 2011-06-20 | 2019-05-31 | H. Lundbeck A/S | Devterirani 1-piperazino-3-fenil indani za zdravljenje shizofrenije |
| CN104628630B (zh) * | 2015-03-16 | 2017-01-18 | 哈尔滨工业大学 | 一种茚衍生物1‑吡啶基‑2‑溴茚及其合成方法 |
| CN104892492A (zh) * | 2015-06-18 | 2015-09-09 | 哈尔滨工业大学 | 一种茚衍生物1-吡啶基-6-甲基茚及其合成方法 |
| JP2021520382A (ja) * | 2018-04-06 | 2021-08-19 | ハー・ルンドベック・アクチエゼルスカベット | ２，２−ジメチルピペラジンの調製方法 |
| EP3873885A1 (en) * | 2018-10-29 | 2021-09-08 | H. Lundbeck A/S | Amorphous compounds of formula (i) and amorphous compounds of formula (i) salts |
| US11535600B2 (en) | 2018-12-03 | 2022-12-27 | H. Lundbeck A/S | Prodrugs of 4-((1R,3S)-6-chloro-3-phenyl-2,3-dihydro-1H-inden-1-yl)-1,2,2-trimethylpiperazine and 4-((1R,3S)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1H-inden-1-yl)-2,2-dimethyl-1-(methyl-d3)piperazine |
| KR102051783B1 (ko) * | 2019-09-02 | 2019-12-03 | 부산대학교 산학협력단 | 3,10-이치환 벤조풀벤 유도체의 신규 합성방법 |
| CN116251081A (zh) * | 2021-12-09 | 2023-06-13 | 复旦大学 | 3-芳基茚酮类化合物及其药物用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62501009A (ja) * | 1984-12-04 | 1987-04-23 | サンド・アクチエンゲゼルシヤフト | メバロノラクトンのインデン同族体及びその誘導体 |
| DE19538218A1 (de) * | 1995-10-13 | 1997-04-17 | Bayer Ag | Cyclopentan-1,3-dion-Derivate |
| WO1999015524A1 (en) * | 1997-09-23 | 1999-04-01 | Fujisawa Pharmaceutical Co., Ltd. | Thiazole derivatives |
| SE9904850D0 (sv) * | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| JP5144930B2 (ja) * | 2003-08-18 | 2013-02-13 | ハー・ルンドベック・アクチエゼルスカベット | トランス−１−（６−クロロ−３−フェニルインダン−１−イル）−３，３−ジメチルピペラジン |
| RU2366654C2 (ru) * | 2004-06-08 | 2009-09-10 | ЭнЭсЭйБи, ФИЛИАЛ АФ НЕУРОСЕРЧ СВИДЕН АБ, СВЕРИЙЕ | Новые дизамещенные фенилпиперидины/пиперазины в качестве модуляторов допаминовой нейротрансмиссии |
| TWI453198B (zh) * | 2005-02-16 | 2014-09-21 | Lundbeck & Co As H | 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s）-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法 |
| WO2007016431A2 (en) * | 2005-07-29 | 2007-02-08 | Concert Pharmaceuticals Inc. | Novel benzo [d] [1,3]-dioxol derivatives |
| WO2008086158A1 (en) * | 2007-01-04 | 2008-07-17 | Smithkline Beecham Corporation | Benzodihydroquinazoline as pi3 kinase inhibitors |
| TW201102370A (en) | 2009-07-07 | 2011-01-16 | Lundbeck & Co As H | Manufacture of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl piperazine |
| KR101149529B1 (ko) * | 2009-09-11 | 2012-05-25 | 한국화학연구원 | 인덴온 유도체 및 이를 포함하는 약학적 조성물 |
| DK2639216T3 (en) | 2010-11-09 | 2018-09-24 | Kaneka Corp | Halogenated Indones and Methods for Preparation of Optically Active Indanones or Optically Active Indanols Using These |
| EP2661427A1 (en) | 2011-01-07 | 2013-11-13 | H. Lundbeck A/S | Method for resolution of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1r,3s)-6-chloro-3-phenyl-indan, 1-yl)-3,3-dimethyl-piperazine |
| SI3135656T1 (sl) * | 2011-06-20 | 2019-05-31 | H. Lundbeck A/S | Devterirani 1-piperazino-3-fenil indani za zdravljenje shizofrenije |
-
2013
- 2013-12-17 AR ARP130104787A patent/AR094054A1/es active IP Right Grant
- 2013-12-19 HR HRP20200385TT patent/HRP20200385T1/hr unknown
- 2013-12-19 EP EP13811511.8A patent/EP2943460B1/en active Active
- 2013-12-19 SI SI201331680T patent/SI2943460T1/sl unknown
- 2013-12-19 MX MX2015007727A patent/MX365707B/es active IP Right Grant
- 2013-12-19 JP JP2015548555A patent/JP6290921B2/ja active Active
- 2013-12-19 KR KR1020157015940A patent/KR102212096B1/ko active Active
- 2013-12-19 PT PT138115118T patent/PT2943460T/pt unknown
- 2013-12-19 LT LTEP13811511.8T patent/LT2943460T/lt unknown
- 2013-12-19 RU RU2015123308A patent/RU2681221C2/ru active
- 2013-12-19 PL PL13811511T patent/PL2943460T3/pl unknown
- 2013-12-19 DK DK13811511.8T patent/DK2943460T3/da active
- 2013-12-19 WO PCT/EP2013/077314 patent/WO2014096151A2/en not_active Ceased
- 2013-12-19 US US14/653,318 patent/US9309165B2/en active Active
- 2013-12-19 SG SG11201504437SA patent/SG11201504437SA/en unknown
- 2013-12-19 AU AU2013366693A patent/AU2013366693B2/en active Active
- 2013-12-19 BR BR112015014384A patent/BR112015014384A2/pt not_active IP Right Cessation
- 2013-12-19 RS RS20200220A patent/RS59982B1/sr unknown
- 2013-12-19 CN CN201380065995.3A patent/CN104955796B/zh active Active
- 2013-12-19 SM SM20200131T patent/SMT202000131T1/it unknown
- 2013-12-19 CA CA2893224A patent/CA2893224C/en active Active
-
2015
- 2015-05-31 IL IL239097A patent/IL239097A/en active IP Right Grant
- 2015-06-18 CL CL2015001720A patent/CL2015001720A1/es unknown
- 2015-06-18 ZA ZA2015/04405A patent/ZA201504405B/en unknown
-
2020
- 2020-03-05 CY CY20201100198T patent/CY1122715T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL235826A0 (en) | Diazaspirocycloalkane and azaspirocycloalkane | |
| IL236616B (en) | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | |
| IL234628A0 (en) | Imidazolyl-pyrimidines are converted into amino-indolyl and their use as drugs | |
| IL237309A0 (en) | Benzocyclooctyne compounds and uses thereof | |
| EP2828258A4 (en) | NOVEL PYRIDOPYRIMIDINE DERIVATIVES AND THEIR USE | |
| IL237926A0 (en) | Combinations and their uses | |
| EP2867209A4 (en) | COMPOUNDS AND THEIR THERAPEUTIC USES | |
| IL251974A0 (en) | Antifibrosis compounds and their uses | |
| ZA201504405B (en) | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof | |
| ZA201405392B (en) | Substituted phenylimidazopyrazoles and use thereof | |
| ZA201407276B (en) | Polypeptides and their use | |
| SG11201504482VA (en) | Beta-hexosyl-transferases and uses thereof | |
| PL2882708T3 (pl) | Nowe związki i ich zastosowania | |
| ZA201408128B (en) | Etract of greyia radlkoferi and use thereof | |
| PL2895751T3 (pl) | Śruba i jej zastosowanie | |
| HUE048382T2 (hu) | 6-klór-3-(fenil-d5)-inden-1-on és alkalmazása | |
| GB201215414D0 (en) | Composition and use | |
| GB201222541D0 (en) | Kiddibidet and pottibidet | |
| IL218974A0 (en) | Conaction bitwen coutch and playels | |
| GB201202021D0 (en) | Co-sleeper and breastfeeder | |
| GB201222342D0 (en) | Compounds and uses thereof | |
| GB201213726D0 (en) | Novel compounds and their use | |
| GB201206055D0 (en) | New compounds and uses |