PL2970378T3 - Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli - Google Patents

Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli

Info

Publication number
PL2970378T3
PL2970378T3 PL14765488T PL14765488T PL2970378T3 PL 2970378 T3 PL2970378 T3 PL 2970378T3 PL 14765488 T PL14765488 T PL 14765488T PL 14765488 T PL14765488 T PL 14765488T PL 2970378 T3 PL2970378 T3 PL 2970378T3
Authority
PL
Poland
Prior art keywords
hydrophobic interaction
chromatography under
salt conditions
interaction protein
protein chromatography
Prior art date
Application number
PL14765488T
Other languages
English (en)
Inventor
Sanchayita Ghose
Yinying TAO
Original Assignee
Biogen Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51537906&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2970378(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Ma Inc. filed Critical Biogen Ma Inc.
Publication of PL2970378T3 publication Critical patent/PL2970378T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
PL14765488T 2013-03-15 2014-03-15 Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli PL2970378T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791238P 2013-03-15 2013-03-15
EP14765488.3A EP2970378B1 (en) 2013-03-15 2014-03-15 Hydrophobic interaction protein chromatography under no-salt conditions
PCT/US2014/029930 WO2014145208A1 (en) 2013-03-15 2014-03-15 Hydrophobic interaction protein chromatography under no-salt conditions

Publications (1)

Publication Number Publication Date
PL2970378T3 true PL2970378T3 (pl) 2021-12-06

Family

ID=51537906

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14765488T PL2970378T3 (pl) 2013-03-15 2014-03-15 Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli

Country Status (6)

Country Link
US (3) US9994609B2 (pl)
EP (2) EP3936515A1 (pl)
JP (1) JP6592426B2 (pl)
DK (1) DK2970378T3 (pl)
PL (1) PL2970378T3 (pl)
WO (1) WO2014145208A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
PL2970378T3 (pl) * 2013-03-15 2021-12-06 Biogen Ma Inc. Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli
US10457720B2 (en) * 2014-03-04 2019-10-29 Merck Patent Gmbh Robust antibody purification
TW201628649A (zh) 2014-10-09 2016-08-16 再生元醫藥公司 減少醫藥調配物中微可見顆粒之方法
CN119119244A (zh) 2016-08-16 2024-12-13 里珍纳龙药品有限公司 用于对混合物中的个体抗体进行量化的方法
FI4071469T3 (fi) 2016-10-25 2025-07-17 Regeneron Pharma Menetelmiä kromatografiatietojen analysointia varten
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
SG11202001564QA (en) 2017-09-19 2020-04-29 Regeneron Pharma Methods of reducing particle formation and compositions formed thereby
TWI853823B (zh) 2018-07-02 2024-09-01 美商里珍納龍藥品有限公司 自混合物製備多肽之系統及方法
CN118909119A (zh) * 2019-06-10 2024-11-08 武田药品工业株式会社 抗体纯化方法及其组合物
JP7787490B2 (ja) 2020-09-03 2025-12-17 Jnc株式会社 疎水性相互作用クロマトグラフィー担体とタンパク質精製方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US7427659B2 (en) 2003-10-24 2008-09-23 Amgen Inc. Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction
EP1711512B1 (en) 2004-01-30 2012-01-11 Amgen Inc. Process for purifying proteins
AU2005296352B2 (en) 2004-10-21 2011-01-06 Cytiva Bioprocess R&D Ab Chromatography ligand
US7408030B2 (en) 2005-01-13 2008-08-05 North Carolina State University Purification of immunoglobulins using affinity chromatography and peptide ligands
CN101384623B (zh) * 2005-12-22 2013-07-24 常山凯捷健生物药物研发（河北）有限公司 白蛋白与治疗剂的预成型偶联物的制备方法
CA2674140C (en) 2007-01-05 2018-05-15 University Of Zurich Method of providing disease-specific binding molecules and targets
CA2673771A1 (en) 2007-01-17 2008-07-24 Merck Serono S.A. Process for the purification of fc-containing proteins
JP2011527338A (ja) 2008-07-09 2011-10-27 ユニバーシティー オブ チューリッヒ 神経新生を促進する方法
NZ590605A (en) 2008-07-09 2012-11-30 Biogen Idec Inc Compositions comprising antibodies to lingo or fragments thereof
US8497358B2 (en) 2008-12-19 2013-07-30 Takeda Pharmaceutical Company Limited Antibody purification method
WO2011046494A1 (en) 2009-10-12 2011-04-21 Ge Healthcare Bio-Sciences Ab Separation matrices
NZ599100A (en) 2009-10-20 2014-07-25 Abbvie Inc Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography
JP5699429B2 (ja) * 2009-12-18 2015-04-08 東ソー株式会社 Ｆｃレセプターの精製方法
EP2649087A1 (en) 2010-12-08 2013-10-16 Amgen Inc. Ion exchange chromatography in the presence of an amino acid
WO2012171853A1 (en) 2011-06-16 2012-12-20 Dsm Ip Assets B.V. Single unit chromatography antibody purification
MX357193B (es) 2011-06-23 2018-06-29 Univ Zuerich Moleculas de union anti-alfa sinucleina.
US9334319B2 (en) * 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
US9249182B2 (en) * 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US11718643B2 (en) 2012-11-13 2023-08-08 Cytiva Bioprocess R&D Ab Multimodal anion exchange matrices
PL2970378T3 (pl) 2013-03-15 2021-12-06 Biogen Ma Inc. Chromatografia oddziaływań hydrofobowych białek w warunkach bez soli
US20160083453A1 (en) 2013-05-13 2016-03-24 Medlmmune, Llc Separation of recombinant polyclonal antibody multimers with minimal separation of monomers
IL320195A (en) 2013-09-13 2025-06-01 Genentech Inc Methods and compositions containing purified recombinant polypeptides
TW202330606A (zh) * 2014-03-21 2023-08-01 美商艾伯維有限公司 抗-egfr抗體及抗體藥物結合物

Also Published As

Publication number Publication date
EP3936515A1 (en) 2022-01-12
US11111269B2 (en) 2021-09-07
US9994609B2 (en) 2018-06-12
US20230391820A1 (en) 2023-12-07
US20190144495A1 (en) 2019-05-16
EP2970378A1 (en) 2016-01-20
WO2014145208A1 (en) 2014-09-18
JP2016515529A (ja) 2016-05-30
JP6592426B2 (ja) 2019-10-16
DK2970378T3 (da) 2021-08-23
US20160024145A1 (en) 2016-01-28
EP2970378A4 (en) 2016-11-16
EP2970378B1 (en) 2021-05-26

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