PL2976072T3 - Drobne cząstki epinefryny i sposoby ich stosowania do leczenia chorób reagujących na epinefrynę - Google Patents
Drobne cząstki epinefryny i sposoby ich stosowania do leczenia chorób reagujących na epinefrynęInfo
- Publication number
- PL2976072T3 PL2976072T3 PL14768584T PL14768584T PL2976072T3 PL 2976072 T3 PL2976072 T3 PL 2976072T3 PL 14768584 T PL14768584 T PL 14768584T PL 14768584 T PL14768584 T PL 14768584T PL 2976072 T3 PL2976072 T3 PL 2976072T3
- Authority
- PL
- Poland
- Prior art keywords
- epinephrine
- treatment
- methods
- fine particles
- conditions responsive
- Prior art date
Links
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 title 2
- 229930182837 (R)-adrenaline Natural products 0.000 title 2
- 229960005139 epinephrine Drugs 0.000 title 2
- 239000010419 fine particle Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361804519P | 2013-03-22 | 2013-03-22 | |
| US201361804892P | 2013-03-25 | 2013-03-25 | |
| PCT/US2014/031579 WO2014153559A1 (en) | 2013-03-22 | 2014-03-24 | Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine |
| EP14768584.6A EP2976072B9 (en) | 2013-03-22 | 2014-03-24 | Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2976072T3 true PL2976072T3 (pl) | 2021-11-22 |
Family
ID=51581536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14768584T PL2976072T3 (pl) | 2013-03-22 | 2014-03-24 | Drobne cząstki epinefryny i sposoby ich stosowania do leczenia chorób reagujących na epinefrynę |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11229613B2 (pl) |
| EP (2) | EP2976072B9 (pl) |
| CA (1) | CA2907770C (pl) |
| DK (1) | DK2976072T3 (pl) |
| ES (1) | ES2882530T3 (pl) |
| HR (1) | HRP20211286T1 (pl) |
| HU (1) | HUE055773T2 (pl) |
| PL (1) | PL2976072T3 (pl) |
| PT (1) | PT2976072T (pl) |
| WO (1) | WO2014153559A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160045457A1 (en) | 2005-09-09 | 2016-02-18 | Ousama Rachid | Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine |
| US9877921B2 (en) | 2005-09-09 | 2018-01-30 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| US20120322884A1 (en) | 2010-03-01 | 2012-12-20 | University Of Manitoba | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| EP2753321B1 (en) | 2011-10-21 | 2021-12-15 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| CA2876883C (en) | 2012-06-15 | 2022-11-01 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| PL2976072T3 (pl) | 2013-03-22 | 2021-11-22 | Nova Southeastern University | Drobne cząstki epinefryny i sposoby ich stosowania do leczenia chorób reagujących na epinefrynę |
| IL272957B2 (en) | 2017-09-06 | 2024-04-01 | pHase Pharmaceuticals LLC | Sublingual epinephrine tablets |
| JP7657457B2 (ja) * | 2018-10-19 | 2025-04-07 | ノバ サウスイースタン ユニバーシティー | ｐＨ修飾賦形剤及び浸入促進剤を含む舌下エピネフリン組成物及びそれを使用する方法 |
| AU2022241136A1 (en) | 2021-03-16 | 2023-11-09 | Robert C H CHISHOLM | Composite oromucosal film compositions comprising epinephrine particles |
| US12414916B2 (en) | 2021-06-10 | 2025-09-16 | Belhaven BioPharma Inc. | Dry powder formulations of epinephrine and associated methods |
| US12502498B1 (en) | 2024-10-21 | 2025-12-23 | Belhaven BioPharma Inc. | Compositions, devices, and methods for intranasal delivery of dry powder epinephrine |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2561916B1 (fr) | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
| US5622716A (en) | 1987-02-20 | 1997-04-22 | Farmarc Nederland B.V. | Process for preparing a retard product containing diltiazem for a single daily administration |
| US5223614A (en) | 1987-12-19 | 1993-06-29 | Boehringer Ingelheim Gmbh | New quaternary ammonium compounds, their preparation and use |
| US5143731A (en) | 1990-08-07 | 1992-09-01 | Mediventures Incorporated | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
| DE69231281T2 (de) | 1991-12-17 | 2001-03-01 | Biovail Technologies Ltd.(N.D.Ges.D.Staates Delaware), Chantilly | Zusammensetzung und verfahren zur ulcusprävention und -behandlung |
| US5654003A (en) | 1992-03-05 | 1997-08-05 | Fuisz Technologies Ltd. | Process and apparatus for making tablets and tablets made therefrom |
| EP0668758A1 (en) | 1992-11-05 | 1995-08-30 | Merck & Co. Inc. | Drug delivery device |
| US20070116761A1 (en) | 1993-02-22 | 2007-05-24 | Desai Neil P | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| US5895664A (en) | 1993-09-10 | 1999-04-20 | Fuisz Technologies Ltd. | Process for forming quickly dispersing comestible unit and product therefrom |
| US5622719A (en) | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
| US5567439A (en) | 1994-06-14 | 1996-10-22 | Fuisz Technologies Ltd. | Delivery of controlled-release systems(s) |
| US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
| US6368625B1 (en) | 1998-08-12 | 2002-04-09 | Cima Labs Inc. | Orally disintegrable tablet forming a viscous slurry |
| US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| US6264981B1 (en) | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| WO2002026223A2 (en) | 2000-09-29 | 2002-04-04 | Board Of Trustees Operating Michigan State University | Catecholamine pharmaceutical compositions and methods |
| US6833377B2 (en) | 2001-02-05 | 2004-12-21 | Gevys Pharmaceuticals Ltd. | Composition and method for potentiating drugs |
| WO2003004009A1 (en) | 2001-07-02 | 2003-01-16 | Geneva Pharmaceuticals, Inc. | Pharmaceutical composition |
| GB0122318D0 (en) * | 2001-09-14 | 2001-11-07 | Novartis Ag | Organic compounds |
| EA007906B1 (ru) | 2002-04-19 | 2007-02-27 | Астион Девелопмент А/С | Комбинация агониста бета-2-адренорецепторов и аминосахара и их применение для лечения иммуномодуляторных расстройств |
| WO2004002551A2 (en) * | 2002-06-28 | 2004-01-08 | Advanced Inhalation Research, Inc. | Inhalable epinephrine |
| US20040121003A1 (en) | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
| US20080069779A1 (en) | 2003-08-04 | 2008-03-20 | Foamix Ltd. | Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof |
| GB0330255D0 (en) | 2003-12-31 | 2004-02-04 | Vectura Ltd | Multiparticulate formulations for oral delivery |
| US9162005B2 (en) | 2005-04-25 | 2015-10-20 | Arch Biosurgery, Inc. | Compositions for prevention of adhesions and other barrier applications |
| MX2007016039A (es) | 2005-06-17 | 2008-10-27 | Univ North Carolina | Metodos, sistemas y materiales de fabricacion de nanoparticulas. |
| US20070202163A1 (en) * | 2005-09-09 | 2007-08-30 | Mutasem Rawas-Qalaji | Fast-disintegrating epinephrine tablets for buccal or sublingual administration |
| WO2007028247A1 (en) | 2005-09-09 | 2007-03-15 | University Of Manitoba | Fast-disintegrating epinephrine tablets for buccal or sublingual administration |
| US20160045457A1 (en) | 2005-09-09 | 2016-02-18 | Ousama Rachid | Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine |
| US9877921B2 (en) | 2005-09-09 | 2018-01-30 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| US20150164827A1 (en) | 2005-09-09 | 2015-06-18 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| US20070092553A1 (en) | 2005-10-21 | 2007-04-26 | Pfab Lp | Compositions and methods of making rapidly dissolving lonically masked formulations |
| US8906392B2 (en) | 2005-12-16 | 2014-12-09 | University Of Kansas | Nanocluster compositions and methods |
| WO2007143674A2 (en) * | 2006-06-05 | 2007-12-13 | Verus Pharmaceuticals, Inc. | Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies |
| CA2669392C (en) | 2006-11-17 | 2016-05-10 | Abbott Gmbh & Co. Kg | Nanocrystals for use in topical cosmetic formulations and method of production thereof |
| US20090263476A1 (en) | 2008-04-16 | 2009-10-22 | Jobdevairakkam Christopher N | Composition of Rapid Disintegrating Direct Compression Buccal Tablet |
| EP2133414A1 (en) | 2008-06-11 | 2009-12-16 | Basf Se | Uses and methods for preventing and /or treating oral malodour |
| JP5985824B2 (ja) | 2008-07-01 | 2016-09-06 | ザ ユニヴァーシティー オヴ シカゴ | オピオイド受容体アンタゴニスト含有の粒子および使用方法 |
| CN101669917B (zh) | 2009-09-23 | 2013-07-24 | 中国人民解放军第二军医大学 | 一种基于“NiMS”系统的氢溴酸东莨菪碱口腔速崩微囊片 |
| CN101841990B (zh) | 2010-01-28 | 2012-05-30 | 鸿富锦精密工业（深圳）有限公司 | 带支撑架的电子设备 |
| US20120322884A1 (en) * | 2010-03-01 | 2012-12-20 | University Of Manitoba | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| EP2753321B1 (en) | 2011-10-21 | 2021-12-15 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| KR20130076015A (ko) | 2011-12-28 | 2013-07-08 | 주식회사 삼양바이오팜 | 높은 경도를 갖는 속붕정 및 이의 제조 방법 |
| CA2876883C (en) | 2012-06-15 | 2022-11-01 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| PL2976072T3 (pl) | 2013-03-22 | 2021-11-22 | Nova Southeastern University | Drobne cząstki epinefryny i sposoby ich stosowania do leczenia chorób reagujących na epinefrynę |
| CN104666401B (zh) | 2015-03-17 | 2019-03-05 | 成都乾坤动物药业股份有限公司 | 一种兽用中西药复方口崩微粉片及其制备方法 |
| ES2724629T3 (es) | 2015-04-08 | 2019-09-12 | Torrent Pharmaceuticals Ltd | Formulaciones farmacéuticas |
| JP7657457B2 (ja) | 2018-10-19 | 2025-04-07 | ノバ サウスイースタン ユニバーシティー | ｐＨ修飾賦形剤及び浸入促進剤を含む舌下エピネフリン組成物及びそれを使用する方法 |
-
2014
- 2014-03-24 PL PL14768584T patent/PL2976072T3/pl unknown
- 2014-03-24 WO PCT/US2014/031579 patent/WO2014153559A1/en not_active Ceased
- 2014-03-24 EP EP14768584.6A patent/EP2976072B9/en active Active
- 2014-03-24 DK DK14768584.6T patent/DK2976072T3/da active
- 2014-03-24 EP EP21170027.3A patent/EP3888642A1/en active Pending
- 2014-03-24 PT PT147685846T patent/PT2976072T/pt unknown
- 2014-03-24 CA CA2907770A patent/CA2907770C/en active Active
- 2014-03-24 HU HUE14768584A patent/HUE055773T2/hu unknown
- 2014-03-24 ES ES14768584T patent/ES2882530T3/es active Active
- 2014-03-24 HR HRP20211286TT patent/HRP20211286T1/hr unknown
-
2018
- 2018-12-19 US US16/225,609 patent/US11229613B2/en active Active
-
2022
- 2022-01-24 US US17/582,045 patent/US20220218629A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20220218629A1 (en) | 2022-07-14 |
| HRP20211286T1 (hr) | 2021-12-24 |
| US20190125698A1 (en) | 2019-05-02 |
| EP2976072B1 (en) | 2021-05-12 |
| EP2976072A4 (en) | 2016-09-07 |
| ES2882530T3 (es) | 2021-12-02 |
| US11229613B2 (en) | 2022-01-25 |
| EP2976072B9 (en) | 2021-10-13 |
| CA2907770A1 (en) | 2014-09-25 |
| DK2976072T3 (da) | 2021-08-16 |
| WO2014153559A1 (en) | 2014-09-25 |
| EP3888642A1 (en) | 2021-10-06 |
| PT2976072T (pt) | 2021-08-12 |
| HUE055773T2 (hu) | 2021-12-28 |
| CA2907770C (en) | 2022-02-15 |
| EP2976072A1 (en) | 2016-01-27 |
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