PL2976074T3 - Antagoniści receptora kannabinoidowego CB1 do zastosowania w leczeniu chorób związanych z neuronowymi nieprawidłowościami dendrytów - Google Patents

Antagoniści receptora kannabinoidowego CB1 do zastosowania w leczeniu chorób związanych z neuronowymi nieprawidłowościami dendrytów

Info

Publication number
PL2976074T3
PL2976074T3 PL13710850T PL13710850T PL2976074T3 PL 2976074 T3 PL2976074 T3 PL 2976074T3 PL 13710850 T PL13710850 T PL 13710850T PL 13710850 T PL13710850 T PL 13710850T PL 2976074 T3 PL2976074 T3 PL 2976074T3
Authority
PL
Poland
Prior art keywords
treatment
receptor antagonists
diseases associated
cannabinoid receptor
neuronal abnormalities
Prior art date
Application number
PL13710850T
Other languages
English (en)
Inventor
Andrés Ozaita Mintegui
Arnau BUSQUETS GARCÍA
Rafael MALDONADO LÓPEZ
Original Assignee
Universitat Pompeu-Fabra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitat Pompeu-Fabra filed Critical Universitat Pompeu-Fabra
Publication of PL2976074T3 publication Critical patent/PL2976074T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL13710850T 2013-03-19 2013-03-19 Antagoniści receptora kannabinoidowego CB1 do zastosowania w leczeniu chorób związanych z neuronowymi nieprawidłowościami dendrytów PL2976074T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13710850.2A EP2976074B1 (en) 2013-03-19 2013-03-19 Antagonists of the cannabionoid receptor cb1 for use in the treatment of diseases associated with neuronal dendritic abnormalities
PCT/EP2013/055728 WO2014146699A1 (en) 2013-03-19 2013-03-19 Antagonists of the cannabionoid receptor cb1 for use in the treatment of diseases associated with neuronal dendritic abnormalities

Publications (1)

Publication Number Publication Date
PL2976074T3 true PL2976074T3 (pl) 2020-07-27

Family

ID=47901995

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13710850T PL2976074T3 (pl) 2013-03-19 2013-03-19 Antagoniści receptora kannabinoidowego CB1 do zastosowania w leczeniu chorób związanych z neuronowymi nieprawidłowościami dendrytów

Country Status (14)

Country Link
US (1) US9662320B2 (pl)
EP (1) EP2976074B1 (pl)
CY (1) CY1122879T1 (pl)
DK (1) DK2976074T3 (pl)
ES (1) ES2781756T3 (pl)
HR (1) HRP20200324T1 (pl)
HU (1) HUE048755T2 (pl)
LT (1) LT2976074T (pl)
PL (1) PL2976074T3 (pl)
PT (1) PT2976074T (pl)
RS (1) RS60295B1 (pl)
SI (1) SI2976074T1 (pl)
SM (1) SMT202000164T1 (pl)
WO (1) WO2014146699A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2487712B (en) 2011-01-04 2015-10-28 Otsuka Pharma Co Ltd Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy
GB2495118B (en) 2011-09-29 2016-05-18 Otsuka Pharma Co Ltd A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD)
GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB2531278A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
GB2531282A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
GB2539472A (en) 2015-06-17 2016-12-21 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2548873B (en) 2016-03-31 2020-12-02 Gw Res Ltd Use of Cannabidiol in the Treatment of SturgeWeber Syndrome
GB2549278B (en) 2016-04-11 2021-02-17 Gw Res Ltd Use of cannabidivarin in the treatment of autism spectrum disorder
GB2549277B (en) 2016-04-11 2021-02-17 Gw Res Ltd Cannabidiolic Acid for use in the Treatment of Autism Spectrum Disorder
GB2551986A (en) 2016-07-01 2018-01-10 Gw Res Ltd Parenteral formulations
GB2551987A (en) 2016-07-01 2018-01-10 Gw Res Ltd Oral cannabinoid formulations
GB2553139A (en) 2016-08-25 2018-02-28 Gw Res Ltd Use of cannabinoids in the treatment of multiple myeloma
GB2557921A (en) 2016-12-16 2018-07-04 Gw Res Ltd Use of cannabinoids in the treatment of angelman syndrome
GB2559774B (en) 2017-02-17 2021-09-29 Gw Res Ltd Oral cannabinoid formulations
IL271464B2 (en) * 2017-06-30 2024-08-01 Chase Therapeutics Corp NK-1 antagonist compositions and methods for use in the treatment of depression
GB2568929A (en) 2017-12-01 2019-06-05 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2569961B (en) 2018-01-03 2021-12-22 Gw Res Ltd Pharmaceutical
EP3669876A1 (en) * 2018-12-18 2020-06-24 Aelis Farma 3béta-(benzyloxy)-17alpha-methyl-pregn-5-en-20-one for use in the treatment of cognitive disorders
US11160757B1 (en) 2020-10-12 2021-11-02 GW Research Limited pH dependent release coated microparticle cannabinoid formulations
EP4525836A4 (en) * 2022-05-18 2026-02-25 Hadasit Medical Res Services&Development Ltd COMBINATION OF ENDOCANNABINOIDS AND MTOR INHIBITORS IN THE TREATMENT OF NEUROENDOCRINE NEOPLASMS
EP4568702A1 (en) 2022-08-12 2025-06-18 Jazz Pharmaceuticals Research UK Limited Oral solid dosage forms comprising cannabinoids

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080255093A1 (en) * 1999-06-14 2008-10-16 Tam Peter Y Compositions and methods for treating obesity and related disorders
US20060172019A1 (en) 2003-03-07 2006-08-03 Ralston Stuart H Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders
EP1737445A4 (en) * 2004-03-19 2007-05-09 Axonyx Inc METHOD FOR TREATING DOWN SYNDROME
US8222293B2 (en) * 2004-05-24 2012-07-17 Regents of the University of Carolina Treating learning deficits with inhibitors of Hmg CoA reductase
WO2006012403A1 (en) * 2004-07-20 2006-02-02 Massachusetts Institute Of Technology Methods of treatment: cell signaling and glutamate release
US20060276549A1 (en) * 2005-05-13 2006-12-07 Jacobson Peer B Combination and use of drugs
PT1983984T (pt) * 2006-02-02 2018-06-14 Novartis Ag Tratamento da esclerosa tuberosa
US20080004313A1 (en) * 2006-06-28 2008-01-03 Mai De Ltd. Preparation of crystalline polymorphs of rimonabant hydrochloride
US8003672B2 (en) * 2008-04-21 2011-08-23 Merck Sharp & Dohme Corp. CB-1 receptor modulator formulations
WO2010020585A1 (en) * 2008-08-18 2010-02-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Serotonin reuptake inhibitors for the treatment of rett syndrome
US20130058915A1 (en) * 2010-03-02 2013-03-07 Children's Medica Center Corporation Methods and compositions for treatment of angelman syndrome and autism spectrum disorders

Also Published As

Publication number Publication date
HUE048755T2 (hu) 2020-08-28
SMT202000164T1 (it) 2020-05-08
ES2781756T3 (es) 2020-09-07
DK2976074T3 (da) 2020-03-30
CY1122879T1 (el) 2021-05-05
WO2014146699A1 (en) 2014-09-25
HRP20200324T1 (hr) 2020-06-12
US9662320B2 (en) 2017-05-30
RS60295B1 (sr) 2020-07-31
US20160067235A1 (en) 2016-03-10
PT2976074T (pt) 2020-03-11
EP2976074B1 (en) 2020-01-01
LT2976074T (lt) 2020-03-25
EP2976074A1 (en) 2016-01-27
SI2976074T1 (sl) 2020-07-31

Similar Documents

Publication Publication Date Title
SI2976074T1 (sl) Antagonisti kanabionidnega receptorja cb1 za uporabo pri tretiranju bolezni v povezavi z nevronskimi dendritičnimi anomalijami
HUE054783T2 (hu) Pridopidin Huntington-kór kezelésében
HUE056006T2 (hu) Kombináció Parkinson-kór kezelésére
IL244748A0 (en) Methods and processes for non-invasive assessment of genetic variations
SG11201509012QA (en) Sobetirome in the treatment of myelination diseases
PT3811943T (pt) Composto para uso no tratamento de distúrbios oculares
HUE068364T2 (hu) Faktor 1 fehérje betegségek kézélésében vagy megelõzésében váló alkalmazásra
HRP20190356T1 (hr) Mimetici kalcitonina za liječenje bolesti i poremećaja
IL240931A0 (en) History 3 - Phenylpropylamine is converted to the treatment of eye diseases and disorders
EP2967062A4 (en) DESETHYLHYDROXYCHLOROQUIN FOR THE TREATMENT OF DISEASES RELATED TO INFLAMMATION
EP2974730A4 (en) MEDICINAL PRODUCTS FOR RESPIRATORY DISEASES
HRP20181554T4 (hr) Tauroursodezoksikolna kiselina (tudca), namijenjena upotrebi u liječenju neurodegenerativnih poremećaja
ZA201507718B (en) The local treatment of inflammatory ophthalmic diseases
HUE045148T2 (hu) Bumetanid parkinson-szindrómás neurodegeneratív betegségek kezelésére
FR3004424B1 (fr) Marchepied amovible d'aeronef, et aeronef
EP3058005C0 (en) IN SITU ALKYLPHENOL ALDEHYDE RESINS
IL246148A0 (en) Treating brain disorders and biomarkers related thereto
EP2949329A4 (en) THERAPEUTIC AGAINST DEMYELINISING DISEASE
HUE047174T2 (hu) Imepitoin epilepsziás rendellenességek kezelésére történõ alkalmazásra macskafélékben
GB201320506D0 (en) Cyclic amino compounds for the use in the treatment of cardiac disorders
UA25914S (uk) Шпилька для з'єднання деталей транспортного засобу
UA28653S (uk) Шворінь поворотного з'єднання частин транспортного засобу
UA26553S (uk) Шворінь поворотного з'єднання частин транспортного засобу
GB201306413D0 (en) The local treatment of ophthalmic diseases
UA27047S (uk) Редуктор до форматора-вулканізатора 75'' та 88''