PL3000888T3 - Sposób przekształcania kwasu ferulowego do waniliny - Google Patents

Sposób przekształcania kwasu ferulowego do waniliny

Info

Publication number
PL3000888T3
PL3000888T3 PL14186796T PL14186796T PL3000888T3 PL 3000888 T3 PL3000888 T3 PL 3000888T3 PL 14186796 T PL14186796 T PL 14186796T PL 14186796 T PL14186796 T PL 14186796T PL 3000888 T3 PL3000888 T3 PL 3000888T3
Authority
PL
Poland
Prior art keywords
vanillin
ferulic acid
converting ferulic
converting
acid
Prior art date
Application number
PL14186796T
Other languages
English (en)
Inventor
Christian Fleige
Alexander Steinbüchel
Manuel PESARO
Florian Meyer
Original Assignee
Symrise Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symrise Ag filed Critical Symrise Ag
Publication of PL3000888T3 publication Critical patent/PL3000888T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01067—Vanillin dehydrogenase (1.2.1.67)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01017—Enoyl-CoA hydratase (4.2.1.17), i.e. crotonase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01101—Trans-feruloyl-CoA hydratase (4.2.1.101)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01034—Trans-feruloyl-CoA synthase (6.2.1.34)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL14186796T 2014-09-29 2014-09-29 Sposób przekształcania kwasu ferulowego do waniliny PL3000888T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14186796.0A EP3000888B1 (en) 2014-09-29 2014-09-29 Process for converting ferulic acid into vanillin

Publications (1)

Publication Number Publication Date
PL3000888T3 true PL3000888T3 (pl) 2019-05-31

Family

ID=51625916

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14186796T PL3000888T3 (pl) 2014-09-29 2014-09-29 Sposób przekształcania kwasu ferulowego do waniliny

Country Status (4)

Country Link
EP (1) EP3000888B1 (pl)
CN (1) CN107075465A (pl)
PL (1) PL3000888T3 (pl)
WO (1) WO2016050654A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107881188B (zh) * 2017-11-20 2021-04-09 上海交通大学 一种全细胞催化剂制备芳香醛和/或芳香醇的方法
CN113088460B (zh) * 2019-12-23 2023-07-28 波顿（上海）生物技术有限公司 一株拟无枝酸菌突变体及其应用
WO2022133269A1 (en) * 2020-12-18 2022-06-23 Basf Se Bioconversion of ferulic acid to vanillin
CN116670295A (zh) * 2020-12-18 2023-08-29 巴斯夫欧洲公司 用于在抑制香草酸形成的情况下产生香草醛的拟无枝酸菌属菌株
CN113637607B (zh) * 2021-08-16 2022-07-12 陕西海斯夫生物工程有限公司 一株拟无枝酸菌及其应用
CN115851803B (zh) * 2022-09-30 2024-09-03 厦门大学 一种高产香草醇的光合细菌构建方法及其应用
CN117417952B (zh) * 2023-10-20 2024-05-24 陕西海斯夫生物工程有限公司 一种提高香兰素产量的重组拟无枝酸菌、其构建方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19850242A1 (de) * 1998-10-31 2000-05-04 Haarmann & Reimer Gmbh Konstruktion von Produktionsstämmen für die Herstellung von substituierten Phenolen durch gezielte Inaktivierung von Genen des Eugenol- und Ferulasäure-Katabolismus
WO2012172108A1 (en) * 2011-06-17 2012-12-20 Symrise Ag Microorganisms and methods for producing substituted phenols
CN102321563B (zh) * 2011-10-24 2013-04-03 江南大学 一株拟无枝酸菌及利用其全细胞转化制备香草醛的方法
CN103060392A (zh) * 2013-01-22 2013-04-24 江南大学 一种利用固定化拟无枝酸菌转化阿魏酸生产香草醛的方法

Also Published As

Publication number Publication date
CN107075465A (zh) 2017-08-18
EP3000888B1 (en) 2018-12-05
WO2016050654A1 (en) 2016-04-07
EP3000888A1 (en) 2016-03-30

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