PL3083997T3 - Diagnostyczne, prognostyczne i terapeutyczne zastosowania długich niekodujących rna w chorobach serca i medycynie regeneracyjnej - Google Patents
Diagnostyczne, prognostyczne i terapeutyczne zastosowania długich niekodujących rna w chorobach serca i medycynie regeneracyjnejInfo
- Publication number
- PL3083997T3 PL3083997T3 PL14828456T PL14828456T PL3083997T3 PL 3083997 T3 PL3083997 T3 PL 3083997T3 PL 14828456 T PL14828456 T PL 14828456T PL 14828456 T PL14828456 T PL 14828456T PL 3083997 T3 PL3083997 T3 PL 3083997T3
- Authority
- PL
- Poland
- Prior art keywords
- prognostic
- diagnostic
- heart disease
- therapeutic uses
- regenerative medicine
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 208000019622 heart disease Diseases 0.000 title 1
- 102000042567 non-coding RNA Human genes 0.000 title 1
- 108091027963 non-coding RNA Proteins 0.000 title 1
- 230000001172 regenerating effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361964591P | 2013-12-20 | 2013-12-20 | |
| EP14828456.5A EP3083997B1 (en) | 2013-12-20 | 2014-12-19 | Diagnostic, prognostic and therapeutic uses of long noncoding rnas for heart disease and regenerative medicine |
| PCT/EP2014/078868 WO2015092020A2 (en) | 2013-12-20 | 2014-12-19 | Diagnostic, prognostic and therapeutic uses of long noncoding rnas for heart disease and regenerative medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3083997T3 true PL3083997T3 (pl) | 2021-04-06 |
Family
ID=52394217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14828456T PL3083997T3 (pl) | 2013-12-20 | 2014-12-19 | Diagnostyczne, prognostyczne i terapeutyczne zastosowania długich niekodujących rna w chorobach serca i medycynie regeneracyjnej |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11193171B2 (pl) |
| EP (2) | EP3083997B1 (pl) |
| DK (1) | DK3083997T3 (pl) |
| ES (1) | ES2837437T3 (pl) |
| HU (1) | HUE051159T2 (pl) |
| IL (3) | IL285107B2 (pl) |
| PL (1) | PL3083997T3 (pl) |
| PT (1) | PT3083997T (pl) |
| SI (1) | SI3083997T1 (pl) |
| WO (1) | WO2015092020A2 (pl) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| EP3563859B1 (en) | 2012-08-13 | 2021-10-13 | Cedars-Sinai Medical Center | Cardiosphere-derived exosomes for tissue regeneration |
| EP4494699A3 (en) | 2014-10-03 | 2025-04-30 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| WO2017123662A1 (en) | 2016-01-11 | 2017-07-20 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| CN105802969A (zh) * | 2016-05-10 | 2016-07-27 | 新疆医科大学第附属医院 | lncRNA ENST00000581794.1及制剂或诊断剂或药物或试剂盒和应用 |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| CN107460234B (zh) * | 2016-06-06 | 2020-06-16 | 王辉云 | 血清48-lncRNA作为肝脏慢性疾病诊断标记物的应用 |
| CN109996893A (zh) * | 2016-07-07 | 2019-07-09 | 西门子医疗有限公司 | 鉴定心脏发育基因模式的表观基因组范围相关的研究和一类新的心力衰竭生物标记物 |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| WO2018191536A1 (en) * | 2017-04-13 | 2018-10-18 | Chi-Hua Foundation | Method for prognosing adverse cardiovascular outcome in patients with coronary artery diseases |
| US20190127795A1 (en) * | 2017-04-13 | 2019-05-02 | Tiffany Wu | Method for prognosing and reducing cardiovascular disease in patients with kidney diseases |
| JP7336769B2 (ja) | 2017-04-19 | 2023-09-01 | シーダーズ―シナイ メディカル センター | 骨格筋ジストロフィーを治療する方法及び組成物 |
| WO2018229046A1 (en) | 2017-06-12 | 2018-12-20 | Firalis Sa | DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC USES OF LONG NONCODING RNAs FOR PATHOLOGIES AND TOXICITIES INDUCING HEART DISORDERS |
| IL271538B2 (en) * | 2017-06-19 | 2025-04-01 | Univ Lausanne | Gene transfer vector, pharmaceutical compositions, for the treatment and prevention of cardiac diseases |
| US11708600B2 (en) * | 2017-10-05 | 2023-07-25 | Decode Health, Inc. | Long non-coding RNA gene expression signatures in disease diagnosis |
| WO2019126068A1 (en) | 2017-12-20 | 2019-06-27 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| CN107948321B (zh) * | 2017-12-29 | 2021-10-12 | 威马智慧出行科技（上海）有限公司 | 车辆的远程授权方法及系统 |
| EP3749344A4 (en) | 2018-02-05 | 2022-01-26 | Cedars-Sinai Medical Center | METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS |
| CN108148908B (zh) * | 2018-03-16 | 2020-05-12 | 中国人民解放军沈阳军区总医院 | 动脉粥样硬化性肾动脉狭窄诊断分子标记物的应用 |
| CN110396542A (zh) * | 2019-05-20 | 2019-11-01 | 徐州市疾病预防控制中心(徐州市健康教育所) | 一种LncRNA标记物及其在糖尿病中的应用 |
| JP2023527766A (ja) * | 2020-05-19 | 2023-06-30 | シーダーズ―シナイ メディカル センター | エキソソーム由来のＰＩＷＩ－ｉｎｔｅｒａｃｔｉｎｇ ＲＮＡおよびその使用方法 |
| CN112176053B (zh) * | 2020-10-12 | 2021-06-25 | 山东大学齐鲁医院(青岛) | 一种急性重症病毒性心肌炎基因标志物 |
| CN113388673B (zh) * | 2021-04-28 | 2022-09-20 | 广东省人民医院 | 长非编码rna carmen的应用 |
| KR102643120B1 (ko) * | 2021-11-12 | 2024-03-05 | 재단법인 아산사회복지재단 | 대동맥판막 협착증의 진단을 위한 미토콘드리아 바이오마커 및 미토콘드리아 활성화제를 포함하는 대동맥판막 협착증의 예방 또는 치료용 약학적 조성물 |
| US20260117226A1 (en) * | 2022-06-30 | 2026-04-30 | Medizinische Hochschule Hannover | Long non-coding rnas as target for treating fibrosis and cancer |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5118937A (en) | 1989-08-22 | 1992-06-02 | Finnigan Mat Gmbh | Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules |
| US5545522A (en) | 1989-09-22 | 1996-08-13 | Van Gelder; Russell N. | Process for amplifying a target polynucleotide sequence using a single primer-promoter complex |
| US5045694A (en) | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
| EP0700521B1 (en) | 1993-05-28 | 2003-06-04 | Baylor College Of Medicine | Method and mass spectrometer for desorption and ionization of analytes |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US5539083A (en) | 1994-02-23 | 1996-07-23 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid combinatorial libraries and improved methods of synthesis |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US6028189A (en) | 1997-03-20 | 2000-02-22 | University Of Washington | Solvent for oligonucleotide synthesis and methods of use |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US7013221B1 (en) | 1999-07-16 | 2006-03-14 | Rosetta Inpharmatics Llc | Iterative probe design and detailed expression profiling with flexible in-situ synthesis arrays |
| AU2004258085B2 (en) | 2003-07-10 | 2010-05-27 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| US7312035B2 (en) * | 2004-09-03 | 2007-12-25 | Affymetrix, Inc. | Methods of genetic analysis of yeast |
| US20140004565A1 (en) | 2009-07-06 | 2014-01-02 | Alnylam Pharmaceuticals, Inc. | Cell-based bioprocessing |
| CN105980615A (zh) * | 2013-08-28 | 2016-09-28 | 卡里斯生命科学瑞士控股有限公司 | 寡核苷酸探针及其用途 |
-
2014
- 2014-12-19 PT PT148284565T patent/PT3083997T/pt unknown
- 2014-12-19 PL PL14828456T patent/PL3083997T3/pl unknown
- 2014-12-19 US US15/105,319 patent/US11193171B2/en active Active
- 2014-12-19 IL IL285107A patent/IL285107B2/en unknown
- 2014-12-19 WO PCT/EP2014/078868 patent/WO2015092020A2/en not_active Ceased
- 2014-12-19 DK DK14828456.5T patent/DK3083997T3/da active
- 2014-12-19 HU HUE14828456A patent/HUE051159T2/hu unknown
- 2014-12-19 EP EP14828456.5A patent/EP3083997B1/en active Active
- 2014-12-19 SI SI201431696T patent/SI3083997T1/sl unknown
- 2014-12-19 EP EP20176907.2A patent/EP3825419A3/en active Pending
- 2014-12-19 ES ES14828456T patent/ES2837437T3/es active Active
-
2016
- 2016-06-08 IL IL246103A patent/IL246103B/en active IP Right Grant
-
2020
- 2020-01-23 IL IL272226A patent/IL272226B/en unknown
-
2021
- 2021-10-19 US US17/505,153 patent/US20220136054A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL285107B1 (en) | 2023-10-01 |
| EP3083997B1 (en) | 2020-07-29 |
| US20220136054A1 (en) | 2022-05-05 |
| WO2015092020A2 (en) | 2015-06-25 |
| EP3825419A2 (en) | 2021-05-26 |
| PT3083997T (pt) | 2020-11-03 |
| ES2837437T3 (es) | 2021-06-30 |
| DK3083997T3 (da) | 2020-10-19 |
| IL272226A (en) | 2020-03-31 |
| IL285107A (en) | 2021-08-31 |
| US11193171B2 (en) | 2021-12-07 |
| SI3083997T1 (sl) | 2020-12-31 |
| IL246103A0 (en) | 2016-07-31 |
| IL246103B (en) | 2020-02-27 |
| WO2015092020A3 (en) | 2015-09-24 |
| IL272226B (en) | 2021-08-31 |
| HUE051159T2 (hu) | 2021-03-01 |
| US20160312283A1 (en) | 2016-10-27 |
| EP3083997A2 (en) | 2016-10-26 |
| EP3825419A3 (en) | 2021-09-15 |
| IL285107B2 (en) | 2024-02-01 |
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