PL3093011T3 - Sposób otrzymywania bezpośrednio tabletkowalnego delta-mannitolu - Google Patents

Sposób otrzymywania bezpośrednio tabletkowalnego delta-mannitolu

Info

Publication number
PL3093011T3
PL3093011T3 PL16001371T PL16001371T PL3093011T3 PL 3093011 T3 PL3093011 T3 PL 3093011T3 PL 16001371 T PL16001371 T PL 16001371T PL 16001371 T PL16001371 T PL 16001371T PL 3093011 T3 PL3093011 T3 PL 3093011T3
Authority
PL
Poland
Prior art keywords
preparation
directly tablettable
mannitol
tablettable mannitol
directly
Prior art date
Application number
PL16001371T
Other languages
English (en)
Inventor
Martin Erdmann
Walter Hamm
Eugen Schwarz
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL3093011T3 publication Critical patent/PL3093011T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/78Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by condensation or crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
PL16001371T 2010-12-17 2011-11-17 Sposób otrzymywania bezpośrednio tabletkowalnego delta-mannitolu PL3093011T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP10015770 2010-12-17
PCT/EP2011/005801 WO2012079671A2 (de) 2010-12-17 2011-11-17 VERFAHREN ZUR HERSTELLUNG VON DIREKT TABLETTIERBAREM δ-MANNIT
EP11784604.8A EP2651397A2 (de) 2010-12-17 2011-11-17 Verfahren zur herstellung von direkt tablettierbarem -mannit
EP16001371.0A EP3093011B1 (de) 2010-12-17 2011-11-17 Verfahren zur herstellung von direkt tablettierbarem delta-mannit

Publications (1)

Publication Number Publication Date
PL3093011T3 true PL3093011T3 (pl) 2021-09-06

Family

ID=44993528

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16001371T PL3093011T3 (pl) 2010-12-17 2011-11-17 Sposób otrzymywania bezpośrednio tabletkowalnego delta-mannitolu

Country Status (7)

Country Link
US (1) US8716536B2 (pl)
EP (2) EP3093011B1 (pl)
JP (2) JP2014501226A (pl)
CN (2) CN103429229A (pl)
HU (1) HUE054747T2 (pl)
PL (1) PL3093011T3 (pl)
WO (1) WO2012079671A2 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2994569B1 (fr) * 2012-08-17 2016-11-04 Roquette Freres Procede de fabrication de compositions riches en cristaux de mannitol sous forme delta, compositions et cristaux obtenus ainsi que leurs utilisations
CN118558277B (zh) * 2024-07-31 2024-11-15 江苏先卓食品科技股份有限公司 一种异麦芽酮糖醇生产用受热均匀型喷雾结晶装置及其方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
PL329614A1 (en) 1996-04-16 1999-03-29 Bayer Ag D-mannitoll and method of obtaining same
DE19615418A1 (de) * 1996-04-22 1997-10-23 Merck Patent Gmbh Polyol-Zusammensetzung
ATE346589T1 (de) * 1997-10-15 2006-12-15 Merck Patent Gmbh Herstellung eines direkt verpressbaren tablettierhilfsstoffes
DE19927537A1 (de) 1999-06-16 2000-12-21 Merck Patent Gmbh Sprühtrocknungsanlage und Verfahren zu ihrer Verwendung
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
DE10240778A1 (de) * 2002-08-30 2004-03-11 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem a-Mannit
EP1623153A1 (de) 2003-05-15 2006-02-08 Lucea AG Lichtquelle
WO2007041479A2 (en) * 2005-09-30 2007-04-12 Smithkline Beecham Corporation Pharmaceutical compositions
US8486450B2 (en) 2005-12-28 2013-07-16 Takeda Pharmaceutical Company Limited Method of producing solid preparation disintegrating in the oral cavity
US8389778B2 (en) * 2007-05-22 2013-03-05 Aptuit (West Lafayette), Llc Preparation of mannitol modification III
JP5694773B2 (ja) * 2008-09-30 2015-04-01 テバ製薬株式会社 圧縮成型製剤およびその製造方法

Also Published As

Publication number Publication date
JP6419759B2 (ja) 2018-11-07
EP3093011B1 (de) 2021-03-24
WO2012079671A2 (de) 2012-06-21
CN103429229A (zh) 2013-12-04
HUE054747T2 (hu) 2021-09-28
JP2014501226A (ja) 2014-01-20
WO2012079671A3 (de) 2012-08-30
US8716536B2 (en) 2014-05-06
EP2651397A2 (de) 2013-10-23
US20130261346A1 (en) 2013-10-03
CN106727355A (zh) 2017-05-31
JP2017036280A (ja) 2017-02-16
EP3093011A1 (de) 2016-11-16

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