PL3151859T3 - Efektywna i skuteczna kontrola stężenia fosforanów w surowicy dla optymalnego tworzenia kości - Google Patents

Efektywna i skuteczna kontrola stężenia fosforanów w surowicy dla optymalnego tworzenia kości

Info

Publication number
PL3151859T3
PL3151859T3 PL15806501T PL15806501T PL3151859T3 PL 3151859 T3 PL3151859 T3 PL 3151859T3 PL 15806501 T PL15806501 T PL 15806501T PL 15806501 T PL15806501 T PL 15806501T PL 3151859 T3 PL3151859 T3 PL 3151859T3
Authority
PL
Poland
Prior art keywords
effective
serum
bone formation
phosphate concentration
optimum bone
Prior art date
Application number
PL15806501T
Other languages
English (en)
Inventor
Emil Kakkis
Javier SAN MARTIN
Tomohiro Sudo
Original Assignee
Ultragenyx Pharmaceutical Inc.
Kyowa Kirin Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ultragenyx Pharmaceutical Inc., Kyowa Kirin Co., Ltd. filed Critical Ultragenyx Pharmaceutical Inc.
Publication of PL3151859T3 publication Critical patent/PL3151859T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/00113—Growth factors
    • A61K39/001132—Fibroblast growth factors [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
PL15806501T 2014-06-09 2015-05-29 Efektywna i skuteczna kontrola stężenia fosforanów w surowicy dla optymalnego tworzenia kości PL3151859T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462009474P 2014-06-09 2014-06-09
PCT/US2015/033226 WO2015191312A1 (en) 2014-06-09 2015-05-29 The effective and efficient control of serum phosphate for optimal bone formation
EP15806501.1A EP3151859B1 (en) 2014-06-09 2015-05-29 The effective and efficient control of serum phosphate for optimal bone formation

Publications (1)

Publication Number Publication Date
PL3151859T3 true PL3151859T3 (pl) 2021-07-26

Family

ID=54769049

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20208220.2T PL3845245T3 (pl) 2014-06-09 2015-05-29 Efektywna i skuteczna kontrola stężenia fosforanów w surowicy dla optymalnego tworzenia kości
PL15806501T PL3151859T3 (pl) 2014-06-09 2015-05-29 Efektywna i skuteczna kontrola stężenia fosforanów w surowicy dla optymalnego tworzenia kości

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL20208220.2T PL3845245T3 (pl) 2014-06-09 2015-05-29 Efektywna i skuteczna kontrola stężenia fosforanów w surowicy dla optymalnego tworzenia kości

Country Status (25)

Country Link
US (5) US10639360B2 (pl)
EP (3) EP3845245B1 (pl)
JP (2) JP6808493B2 (pl)
KR (4) KR20210099180A (pl)
CN (1) CN106604743A (pl)
AR (2) AR100689A1 (pl)
AU (1) AU2015275128C1 (pl)
BR (2) BR112016028567A2 (pl)
CA (1) CA2949234C (pl)
CL (1) CL2016003179A1 (pl)
CY (1) CY1124328T1 (pl)
DK (2) DK3845245T3 (pl)
ES (2) ES3040805T3 (pl)
FI (1) FI3845245T3 (pl)
HR (2) HRP20210250T1 (pl)
HU (2) HUE053271T2 (pl)
LT (2) LT3151859T (pl)
MX (2) MX381052B (pl)
PE (1) PE20170248A1 (pl)
PL (2) PL3845245T3 (pl)
PT (2) PT3845245T (pl)
RS (2) RS67294B1 (pl)
SI (2) SI3845245T1 (pl)
SM (2) SMT202100096T1 (pl)
WO (1) WO2015191312A1 (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1759001T3 (pl) 2004-04-21 2011-09-30 Alexion Pharma Inc Koniugaty dostarczane do kości i sposób ich zastosowania do nakierowywania białek do kości
DK3845245T3 (da) 2014-06-09 2025-09-15 Ultragenyx Pharmaceutical Inc Effektiv og virkningsfuld kontrol af serumphosphat til optimal knogledannelse
WO2016007873A1 (en) 2014-07-11 2016-01-14 The Regents Of The University Of Michigan Compositions and methods for treating craniosynostosis
JP6787894B2 (ja) 2014-12-05 2020-11-18 アレクシオン ファーマシューティカルズ， インコーポレイテッド 組換えアルカリホスファターゼを用いた発作の処置
CA2973883A1 (en) 2015-01-28 2016-08-04 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
JP6993961B2 (ja) 2015-08-17 2022-01-14 アレクシオン ファーマシューティカルズ， インコーポレイテッド アルカリホスファターゼの製造
EP3355904A4 (en) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. IDENTIFICATION OF EFFECTIVE DOSE SHEETS FOR TISSUE-SPECIFIC ALKALINE PHOSPHATASE ENZYMERSAT THERAPY OF HYPOPHOSPHATASIA
EP3368062A4 (en) 2015-10-30 2019-07-03 Alexion Pharmaceuticals, Inc. METHODS OF TREATING CRANIOSYNOSTOSIS IN A PATIENT
US11065306B2 (en) 2016-03-08 2021-07-20 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in children
US10898549B2 (en) 2016-04-01 2021-01-26 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in adolescents and adults
KR20180125979A (ko) 2016-04-01 2018-11-26 알렉시온 파마슈티칼스, 인코포레이티드 알칼리성 포스파타아제로 근육 약화의 치료
WO2017214130A1 (en) 2016-06-06 2017-12-14 Alexion Pharmaceuticals, Inc. Metal impact on manufacturing of alkaline phosphatases
JP7018933B2 (ja) 2016-08-18 2022-02-14 アレクシオン ファーマシューティカルズ， インコーポレイテッド 気管気管支軟化症の治療方法
CN106709662B (zh) * 2016-12-30 2021-07-02 山东鲁能软件技术有限公司 一种电力设备运行工况划分方法
KR20190129058A (ko) 2017-03-31 2019-11-19 알렉시온 파마슈티칼스, 인코포레이티드 성인 및 청소년에서 저포스파타제증 (hpp)을 치료하는 방법
WO2019190752A1 (en) 2018-03-30 2019-10-03 Alexion Pharmaceuticals, Inc. Manufacturing of glycoproteins
WO2020033867A2 (en) 2018-08-10 2020-02-13 Alexion Pharmaceuticals, Inc. Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
PH12021552414A1 (en) * 2019-03-29 2022-07-25 Atarga Llc Anti fgf23 antibody
CA3161266A1 (en) 2019-12-09 2021-06-17 Alexion Pharmaceuticals, Inc. Alkaline phosphatase polypeptides and methods of use thereof
US12611447B2 (en) 2020-09-04 2026-04-28 Alexion Pharmaceuticals, Inc. Methods for treating bone mineralization disorders
AU2022218782B2 (en) 2021-02-12 2026-06-25 Alexion Pharmaceuticals, Inc. Alkaline phosphatase polypeptides and methods of use thereof
TW202502815A (zh) * 2023-03-10 2025-01-16 美商超基因克斯製藥公司 具有改良之親和力及功效之人類ｆｇｆ２３結合抗體

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5096815A (en) 1989-01-06 1992-03-17 Protein Engineering Corporation Generation and selection of novel dna-binding proteins and polypeptides
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
DE69233528T2 (de) 1991-11-25 2006-03-16 Enzon, Inc. Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
AU2005202100A1 (en) 1999-05-11 2005-06-09 Ortho-Mcneil Pharmaceutical, Inc. Pharmacokinetic and pharmacodynamic modeling of erythropoietin administration
KR20080023768A (ko) 2000-03-30 2008-03-14 화이트헤드 인스티튜트 포 바이오메디칼 리서치 Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체
JP2004504063A (ja) 2000-07-19 2004-02-12 アドバンスド　リサーチ　＆　テクノロジー　インスティテュート 新規線維芽細胞増殖因子（ｆｇｆ２３）および使用方法
CN101275136A (zh) 2000-08-11 2008-10-01 麒麟医药株式会社 调节磷酸代谢,钙代谢,钙化和维生素d代谢的多肽及其编码dna
DE60131456T2 (de) 2000-11-30 2008-07-10 Medarex, Inc., Milpitas Transchromosomale transgen-nagetiere zur herstellung von humanen antikörpern
DE60329070D1 (de) * 2001-12-28 2009-10-15 Kyowa Hakko Kirin Co Ltd Antikörper gegen den fibroblastenwachstumsfaktor 23
EP1833848A2 (en) * 2004-12-09 2007-09-19 Lajolla Institute for Allergy and Immunology Novel tnf receptor regulatory domain
US8158725B2 (en) 2005-08-22 2012-04-17 Bridgestone Corporation Functionalized polymers and tires therefrom
US7883705B2 (en) 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
US8889621B2 (en) 2009-10-30 2014-11-18 New York University Inhibiting binding of FGF23 to the binary FGFR-Klotho complex for the treatment of hypophosphatemia
WO2012050673A1 (en) 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Methods for the treatment of x-linked hypophosphatemia and related disorders
US9982023B2 (en) * 2011-11-15 2018-05-29 Sanford-Burnham Medical Research Institute Compositions and methods for treating autoimmune and inflammatory disorders
DK3845245T3 (da) 2014-06-09 2025-09-15 Ultragenyx Pharmaceutical Inc Effektiv og virkningsfuld kontrol af serumphosphat til optimal knogledannelse

Also Published As

Publication number Publication date
LT3845245T (lt) 2025-09-25
KR20210099180A (ko) 2021-08-11
AR100689A1 (es) 2016-10-26
JP2021050226A (ja) 2021-04-01
KR102947335B1 (ko) 2026-04-03
AR131056A2 (es) 2025-02-12
CN106604743A (zh) 2017-04-26
AU2015275128B2 (en) 2019-10-31
PT3845245T (pt) 2025-09-16
KR20170013993A (ko) 2017-02-07
US20260035449A1 (en) 2026-02-05
ES2851674T3 (es) 2021-09-08
HUE073105T2 (hu) 2025-12-28
US20200330575A1 (en) 2020-10-22
HRP20210250T1 (hr) 2021-04-02
PL3845245T3 (pl) 2025-12-22
EP3151859B1 (en) 2020-11-25
US11202822B2 (en) 2021-12-21
HUE053271T2 (hu) 2021-06-28
RS67294B1 (sr) 2025-11-28
US20150353633A1 (en) 2015-12-10
DK3845245T3 (da) 2025-09-15
MX2016016296A (es) 2017-10-12
PT3151859T (pt) 2021-02-03
JP6808493B2 (ja) 2021-01-06
SMT202100096T1 (it) 2021-03-15
AU2015275128C1 (en) 2020-02-13
EP3845245A1 (en) 2021-07-07
EP3151859A1 (en) 2017-04-12
PE20170248A1 (es) 2017-04-14
CL2016003179A1 (es) 2017-11-03
CA2949234C (en) 2022-03-22
FI3845245T3 (fi) 2025-09-09
SI3151859T1 (sl) 2021-06-30
CA2949234A1 (en) 2015-12-17
JP2017524656A (ja) 2017-08-31
AU2015275128A1 (en) 2016-12-08
KR20260051107A (ko) 2026-04-15
US10639360B2 (en) 2020-05-05
SI3845245T1 (sl) 2025-10-30
US20240115683A1 (en) 2024-04-11
US12358976B2 (en) 2025-07-15
HRP20251099T1 (hr) 2025-11-07
MX381052B (es) 2025-03-12
JP6993490B2 (ja) 2022-02-03
BR112016028567A2 (pt) 2018-01-30
US11771748B2 (en) 2023-10-03
KR20240093956A (ko) 2024-06-24
WO2015191312A1 (en) 2015-12-17
BR122023023102A2 (pt) 2024-03-05
EP4647444A2 (en) 2025-11-12
EP4647444A3 (en) 2026-01-21
US20220133871A1 (en) 2022-05-05
EP3845245B1 (en) 2025-06-25
LT3151859T (lt) 2021-03-25
EP3151859A4 (en) 2018-01-17
SMT202500342T1 (it) 2025-11-10
ES3040805T3 (en) 2025-11-05
MX2021003740A (es) 2021-05-27
CY1124328T1 (el) 2022-07-22
DK3151859T3 (da) 2021-02-15
RS61443B1 (sr) 2021-03-31

Similar Documents

Publication Publication Date Title
FIC20250034I1 (fi) O-deuteroitu atropiini ja erityisesti O-deuteroidun atropiinin deuterohemisulfaattisuola
DK3845245T3 (da) Effektiv og virkningsfuld kontrol af serumphosphat til optimal knogledannelse
PL3353210T3 (pl) Przeciwciała anty-TIGIT i sposoby stosowania
EP4368124C0 (en) LARGE VOLUME TISSUE REDUCTION AND ELIMINATION SYSTEM
PL3123802T3 (pl) System i sposób dla fizycznego dostępu losowego opartego na wiązce
PL3708668T3 (pl) Sztuczne cząsteczki kwasu nukleinowego dla poprawy ekspresji białka
PL3215532T3 (pl) Przeciwciała anty-TIM3 i sposoby ich zastosowania
SI3258951T1 (sl) Anti-pvrig protitelesa in metode uporabe
IL250318B (en) Protein kinase c inhibitors and methods of using them
FI20155024L (fi) Menetelmä ja järjestelmä kalsiumkarbonaatin saostamiseksi sekä menetelmän käyttö
PT3094727T (pt) Materiais e métodos para a modulação da cura de tendões
ES2808978T8 (es) Heteroarilamidas como inhibidores de la agregación de proteínas
IL251759B (en) Compositions and methods for treating insomnia
IL246269B (en) Compositions and methods for treating fatty tissue buildup
PL3352752T3 (pl) Wykrywanie i leczenie niedoboru hormonu wzrostu
FI20145918A7 (fi) Vedenkäsittelyjärjestelmä ja -menetelmä
IL251421B (en) Use of neridronic acid or of its salt for the treatment of osteoarthrosis
TH1501007103A (th) องค์รวมของแอนตี้-pd-l1 แอนตี้บอดี้และตัวยับยั้ง mek และ/หรือตัวยับยั้ง braf
TH1501006563A (th) วิธีการสำหรับการเก็บ และ/หรือ การขนส่งอนุภาคแลกไทด์
TH1601000318A (th) สารประกอบเเละวิธีการเพื่อการสะสมเเร่ธาตุทางทันตกรรม
TH1601000123A (th) วิธีสำหรับการส่งเสริมการพัฒนาและ/หรือ สุขภาพของเซลล์ประสาท
ITUB20151974A1 (it) Metodo e sistema di certificazione temporale
TH1601000809B (th) วิธีการและระบบสำหรับการรับรองและการตรวจสอบอัญมณี
TH1601000124A (th) วิธีสำหรับการส่งเสริมการพัฒนา และ/หรือ สุขภาพของเซลล์ประสาทซึ่งประกอบ รวมด้วยการให้สารรวมของโดโคซาเฮกซาอีโนอิกแอซิด และอัลฟา-ไลโปอิคแอซิด
FI20145005A7 (fi) Ajovoimansiirtojärjestelmä ja menetelmä