PL3160984T3 - Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylol- fenyloalaninoamidu - Google Patents

Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylol- fenyloalaninoamidu

Info

Publication number: PL3160984T3
Authority: PL; Poland
Prior art keywords: phenylalaninamide; tyrosyl; arginyl; lysyl; dimethyl
Prior art date: 2014-06-25

Application number

PL15738001T

Other languages

English (en)

Inventor

Xinjun Zhao

Minyu ZHENG

Xiaozhong YU

Hanrong Gao

Fabrice Cornille

Original Assignee

Flamma S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-06-25

Filing date

2015-06-24

Publication date

2021-10-25

2015-06-24 Application filed by Flamma S.P.A. filed Critical Flamma S.P.A.

2021-10-25 Publication of PL3160984T3 publication Critical patent/PL3160984T3/pl

Links

SFVLTCAESLKEHH-WKAQUBQDSA-N (2s)-6-amino-2-[[(2s)-2-[[(2r)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-n-[(2s)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide Chemical compound CC1=CC(O)=CC(C)=C1C[C@H](NC(=O)[C@H](N)CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N)=O)CC1=CC=CC=C1 SFVLTCAESLKEHH-WKAQUBQDSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL15738001T 2014-06-25 2015-06-24 Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylol- fenyloalaninoamidu PL3160984T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201462016783P	2014-06-25	2014-06-25
PCT/EP2015/064301 WO2015197723A1 (en)	2014-06-25	2015-06-24	Process for preparing d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide
EP15738001.5A EP3160984B1 (en)	2014-06-25	2015-06-24	Process for preparing d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide

Publications (1)

Publication Number	Publication Date
PL3160984T3 true PL3160984T3 (pl)	2021-10-25

Family

ID=53546576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL15738001T PL3160984T3 (pl)	2014-06-25	2015-06-24	Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylol- fenyloalaninoamidu

Country Status (8)

Country	Link
US (1)	US10125164B2 (pl)
EP (1)	EP3160984B1 (pl)
JP (1)	JP2017523956A (pl)
ES (1)	ES2869430T3 (pl)
HU (1)	HUE054626T2 (pl)
PL (1)	PL3160984T3 (pl)
SI (1)	SI3160984T1 (pl)
WO (1)	WO2015197723A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2016539931A (ja) *	2013-10-23	2016-12-22	株式会社カネカ	テトラペプチド化合物及びその製造方法
PL3160985T3 (pl) *	2014-06-30	2021-12-27	Flamma S.P.A.	Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylo-l-fenyloalaninoamidu
EP4218785A3 (en) *	2017-12-15	2023-08-09	Stealth BioTherapeutics Inc.	Mitochondria-targeting peptides
US11795196B2 (en)	2017-12-15	2023-10-24	Stealth Biotherapeutics Inc.	Mitochondria-targeting peptides
US20230227499A1 (en) *	2020-06-22	2023-07-20	Stealth Biotherapeutics Inc.	Prodrugs of mitochondria-targeting oligopeptides

Family Cites Families (17)

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Publication number	Priority date	Publication date	Assignee	Title
IT1184317B (it) *	1985-02-05	1987-10-28	Eniricerche Spa	Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a
SE9900961D0 (sv)	1999-03-16	1999-03-16	Astra Ab	Novel compounds
ES2436011T3 (es)	2003-02-04	2013-12-26	Cornell Research Foundation, Inc.	Métodos para prevenir la transición de la permeabilidad mitocondrial
CN100506841C (zh) *	2003-05-01	2009-07-01	科内尔研究基金会	将分子递送到细胞的方法和载体复合物
RU2376028C2 (ru)	2004-01-23	2009-12-20	Корнелл Рисеч Фаундейшн, Инк.	Способ уменьшения окислительного повреждения (варианты)
WO2007027742A2 (en)	2005-08-31	2007-03-08	The Trustees Of The University Of Pennsylvania	SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS
WO2007099656A1 (ja) *	2006-03-01	2007-09-07	Kaneka Corporation	ペプチドの製造方法
DK2262520T3 (en)	2008-02-26	2017-08-07	Univ Cornell	COMPOSITIONS FOR PREVENTION AND TREATMENT OF Kidney Injury
US20110245183A1 (en)	2010-04-06	2011-10-06	Perricone Nicholas V	Topical Uses of Szeto-Schiller Peptides
US20110245182A1 (en)	2010-04-06	2011-10-06	Perricone Nicholas V	Topical Uses of Szeto-Schiller Peptides
US20120083452A1 (en)	2010-09-30	2012-04-05	Perricone Nicholas V	Topical Anesthetic Uses of Szeto-Schiller Peptides
CN103764159A (zh)	2011-06-14	2014-04-30	康肽德生物医药技术有限公司	芳香族阳离子肽及其用途
EP3466439A1 (en)	2011-12-09	2019-04-10	Stealth Peptides International, Inc.	Aromatic-cationic peptides and uses of same
CA2916492A1 (en)	2013-06-27	2014-12-31	Stealth Biotherapeutics Corp	Peptide therapeutics and methods for using same
JP2016539931A (ja) *	2013-10-23	2016-12-22	株式会社カネカ	テトラペプチド化合物及びその製造方法
CA2935207C (en) *	2013-12-27	2022-06-21	Stealth Biotherapeutics Corp	Pharmaceutically relevant aromatic-cationic peptides
PL3160985T3 (pl) *	2014-06-30	2021-12-27	Flamma S.P.A.	Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylo-l-fenyloalaninoamidu

2015
- 2015-06-24 EP EP15738001.5A patent/EP3160984B1/en active Active
- 2015-06-24 JP JP2016574053A patent/JP2017523956A/ja active Pending
- 2015-06-24 SI SI201531587T patent/SI3160984T1/sl unknown
- 2015-06-24 US US15/319,858 patent/US10125164B2/en active Active
- 2015-06-24 ES ES15738001T patent/ES2869430T3/es active Active
- 2015-06-24 HU HUE15738001A patent/HUE054626T2/hu unknown
- 2015-06-24 PL PL15738001T patent/PL3160984T3/pl unknown
- 2015-06-24 WO PCT/EP2015/064301 patent/WO2015197723A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP3160984A1 (en)	2017-05-03
EP3160984B1 (en)	2021-04-14
JP2017523956A (ja)	2017-08-24
SI3160984T1 (sl)	2021-08-31
ES2869430T3 (es)	2021-10-25
HUE054626T2 (hu)	2021-09-28
US20170129920A1 (en)	2017-05-11
US10125164B2 (en)	2018-11-13
WO2015197723A1 (en)	2015-12-30

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