PL3176164T3 - Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem - Google Patents

Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem

Info

Publication number
PL3176164T3
PL3176164T3 PL15826775T PL15826775T PL3176164T3 PL 3176164 T3 PL3176164 T3 PL 3176164T3 PL 15826775 T PL15826775 T PL 15826775T PL 15826775 T PL15826775 T PL 15826775T PL 3176164 T3 PL3176164 T3 PL 3176164T3
Authority
PL
Poland
Prior art keywords
benzothiazepine
pharmaceutical composition
same
composition prepared
optical isomer
Prior art date
Application number
PL15826775T
Other languages
English (en)
Inventor
Noboru Kaneko
Original Assignee
Aetas Pharma Co. Ltd.
Noboru Kaneko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aetas Pharma Co. Ltd., Noboru Kaneko filed Critical Aetas Pharma Co. Ltd.
Publication of PL3176164T3 publication Critical patent/PL3176164T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL15826775T 2014-07-30 2015-07-17 Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem PL3176164T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014155068 2014-07-30
PCT/JP2015/070488 WO2016017448A1 (ja) 2014-07-30 2015-07-17 １，４－ベンゾチアゼピン－１－オキシド誘導体の光学異性体、及びそれを用いた医薬組成物
EP15826775.7A EP3176164B1 (en) 2014-07-30 2015-07-17 Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same

Publications (1)

Publication Number Publication Date
PL3176164T3 true PL3176164T3 (pl) 2020-05-18

Family

ID=55217353

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15826775T PL3176164T3 (pl) 2014-07-30 2015-07-17 Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem

Country Status (12)

Country Link
US (1) US10071996B2 (pl)
EP (1) EP3176164B1 (pl)
JP (1) JP6574773B2 (pl)
KR (1) KR102091211B1 (pl)
CN (1) CN106795148B (pl)
AU (1) AU2015297705B2 (pl)
CA (1) CA2956699C (pl)
DK (1) DK3176164T3 (pl)
ES (1) ES2750580T3 (pl)
PL (1) PL3176164T3 (pl)
TW (1) TWI572603B (pl)
WO (1) WO2016017448A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2965277T3 (es) * 2016-06-27 2024-04-11 Glaxosmithkline Ip No 2 Ltd Métodos de síntesis
EP3725315B1 (en) * 2017-12-11 2023-10-04 Aetas Pharma Co. Ltd. Renal dysfunction improving drug comprising optical isomer of 1,4-benzothiazepine-1-oxide derivative
JP7595011B2 (ja) * 2019-07-22 2024-12-05 株式会社アエタスファルマ 光学活性な１，４－ベンゾチアゼピン－１－オキシド誘導体の製造方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS488825Y1 (pl) 1970-06-12 1973-03-08
GB9009389D0 (en) 1990-04-26 1990-06-20 Smith Kline French Lab Treatment
JP2703408B2 (ja) 1990-12-28 1998-01-26 麒麟麦酒株式会社 １，４‐ベンゾチアゼピン誘導体
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
JP4064027B2 (ja) 1998-12-28 2008-03-19 金子 昇 心房細動治療薬
US6506745B1 (en) 1998-12-28 2003-01-14 Noboru Kaneko Medicinal compositions for treatment of atrial fibrillation
JP4041642B2 (ja) 1999-05-19 2008-01-30 昇 金子 制癌剤耐性克服剤および制癌剤効果増強剤
DE60021075T2 (de) 1999-05-19 2006-05-24 Noboru Kaneko Verwendung von 1,4-benzothiazepinderivaten als arzneimittel zur überwindung einer resistenz gegenüber einem arzneimittel gegen krebs
BR0113073A (pt) 2000-08-07 2004-06-22 Glaxosmithkline Lab Sas Uso de antagonistas receptores 5ht4 na fabricação de um medicamento para a profilaxia ou tratamento de fibrilação atrial
JP2003095977A (ja) 2001-09-21 2003-04-03 Masafumi Yano 筋肉収縮・弛緩機能障害関連疾患の治療又は予防剤
CA2565024A1 (en) 2004-04-28 2005-11-10 Aetas Pharma Co., Ltd. Therapeutic agent for left ventricular diastolic dysfunction
WO2007053610A2 (en) 2005-11-01 2007-05-10 The Regents Of The University Of California Methods of treating atrial fibrillation wtih pirfenidone
WO2008004245A1 (en) * 2006-07-05 2008-01-10 Lupin Limited Process for the preparation of optically pure or optically enriched enantiomers of sulphoxide compounds
US8642586B2 (en) 2009-02-25 2014-02-04 Noboru Kaneko 1,4-benzothiazepine-1-oxide derivative and pharmaceutical composition utilizing the same
WO2010114562A1 (en) * 2009-04-03 2010-10-07 Sequel Pharmaceuticals, Inc. Improved methods of administration of k201 (jtv-519) (4-[3-{1-(4-benzyl) piperidinyl}propionyl]-7-methoxy 2, 3, 4, 5-tetrahydro-1, 4-benzothiazepine monohydrochloride)
FR2963790B1 (fr) 2010-08-11 2012-09-28 Pf Medicament Docosahexaeneoate de panthenyle et son utilisation dans le traitement et la prevention des maladies cardiovasculaires
JP2012184225A (ja) 2011-02-18 2012-09-27 Otsuka Pharmaceut Co Ltd 医薬組成物
EP2708535A1 (en) 2012-05-11 2014-03-19 Les Laboratoires Servier Agents for treating disorders involving modulation of ryanodine receptors

Also Published As

Publication number Publication date
CA2956699A1 (en) 2016-02-04
TW201607945A (zh) 2016-03-01
DK3176164T3 (da) 2019-10-28
US10071996B2 (en) 2018-09-11
CN106795148A (zh) 2017-05-31
CA2956699C (en) 2020-09-29
KR20170031712A (ko) 2017-03-21
CN106795148B (zh) 2019-12-10
JPWO2016017448A1 (ja) 2017-05-18
EP3176164B1 (en) 2019-08-21
EP3176164A4 (en) 2018-01-03
AU2015297705B2 (en) 2019-12-19
US20170247362A1 (en) 2017-08-31
WO2016017448A1 (ja) 2016-02-04
JP6574773B2 (ja) 2019-09-11
AU2015297705A1 (en) 2017-03-02
ES2750580T3 (es) 2020-03-26
EP3176164A1 (en) 2017-06-07
KR102091211B1 (ko) 2020-03-19
TWI572603B (zh) 2017-03-01

Similar Documents

Publication Publication Date Title
IL254124A0 (en) New 3-indole-transformed histories, medicinal preparations and methods of use
EP3139920A4 (en) Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
PT3339294T (pt) Derivado de quinolona, sal farmaceuticamente aceitável ou estereoisómero do mesmo como inibidor de axl
EP3357513A4 (en) Pharmaceutical composition and application thereof
SI3426348T1 (sl) Derivat 3-dezoksi in njegovi farmacevtski sestavki
EP3102200A4 (en) Therapeutic compounds and compositions
EP3302439A4 (en) Therapeutic composition
EP3297640A4 (en) Pharmaceutical co-crystal composition and use thereof
EP3202759A4 (en) Alpha-aminoamide derivative compound and pharmaceutical composition comprising same
EP3141243A4 (en) Pharmaceutical composition
EP3285758A4 (en) Co-crystal composition and its pharmaceutical use
ZA201804203B (en) Pharmaceutical compositions comprising phenylaminopyrimidine derivative
EP3185873A4 (en) Pharmaceutical composition and methods
IL263040A (en) Pharmaceutical composition comprising eteplirsen
EP3272362A4 (en) Sustained-release pharmaceutical composition
EP3279205A4 (en) Phytospingosine derivative and composition containing same
EP3244895A4 (en) Novel pharmaceutical composition
IL257621B (en) A catechol derivative and a pharmaceutical preparation that includes it
EP3176164A4 (en) Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same
EP3496714A4 (en) DRUG COMPOSITIONS.
ZA202000959B (en) Adamantylmethylamine derivative and use thereof as pharmaceutical
EP3205343A4 (en) Pharmaceutical composition of fused aminodihydrothiazine derivative
EP3170512A4 (en) Pharmaceutical composition
EP3533448A4 (en) STABLE PHARMACEUTICAL COMPOSITION
PL3424500T3 (pl) Kompozycja farmaceutyczna zawierająca famitynib