PL3194360T3 - Pochodne 4-okso-N-(4-hydroksyfenylo)retinamidu jako środki terapeutyczne do leczenia raka - Google Patents
Pochodne 4-okso-N-(4-hydroksyfenylo)retinamidu jako środki terapeutyczne do leczenia rakaInfo
- Publication number
- PL3194360T3 PL3194360T3 PL15775638T PL15775638T PL3194360T3 PL 3194360 T3 PL3194360 T3 PL 3194360T3 PL 15775638 T PL15775638 T PL 15775638T PL 15775638 T PL15775638 T PL 15775638T PL 3194360 T3 PL3194360 T3 PL 3194360T3
- Authority
- PL
- Poland
- Prior art keywords
- hydroxyphenyl
- oxo
- cancer
- treatment
- therapeutic agents
- Prior art date
Links
- NZVOGZATHCUFRC-KFJFTADJSA-N (2e,4e,6e,8e)-n-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenamide Chemical class C=1C=C(O)C=CC=1NC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)CCC1(C)C NZVOGZATHCUFRC-KFJFTADJSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
- C07C251/60—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI20141603 | 2014-09-17 | ||
| PCT/EP2015/071178 WO2016042010A1 (en) | 2014-09-17 | 2015-09-16 | 4-oxo-n-(4-hydroxyphenyl)retinamide derivatives as therapeutic agents for the treatment of cancer |
| EP15775638.8A EP3194360B1 (en) | 2014-09-17 | 2015-09-16 | 4-oxo-n-(4-hydroxyphenyl)retinamide derivatives as therapeutic agents for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3194360T3 true PL3194360T3 (pl) | 2018-11-30 |
Family
ID=51799184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15775638T PL3194360T3 (pl) | 2014-09-17 | 2015-09-16 | Pochodne 4-okso-N-(4-hydroksyfenylo)retinamidu jako środki terapeutyczne do leczenia raka |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10093621B2 (pl) |
| EP (1) | EP3194360B1 (pl) |
| JP (1) | JP6654771B2 (pl) |
| KR (1) | KR102547925B1 (pl) |
| CN (1) | CN107001258B (pl) |
| AU (1) | AU2015316886B2 (pl) |
| CA (1) | CA2961275C (pl) |
| CY (1) | CY1121920T1 (pl) |
| DK (1) | DK3194360T3 (pl) |
| ES (1) | ES2686733T3 (pl) |
| HR (1) | HRP20181460T1 (pl) |
| HU (1) | HUE039947T2 (pl) |
| PL (1) | PL3194360T3 (pl) |
| PT (1) | PT3194360T (pl) |
| RS (1) | RS57443B1 (pl) |
| SI (1) | SI3194360T1 (pl) |
| WO (1) | WO2016042010A1 (pl) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399757A (en) * | 1993-07-20 | 1995-03-21 | Ortho Pharmaceutical Corporation | Process for the preparation of N-(4-hydroxyphenyl)-retinamide |
| JP4384409B2 (ja) * | 2000-12-05 | 2009-12-16 | チルドレンズ・ホスピタル・ロス・アンジエルス | バイオアベイラビリティが増加したフェンレチニドの医薬組成物、およびその使用方法 |
| US20030232820A1 (en) | 2001-08-29 | 2003-12-18 | Saul Wolfe | Method for synthesizing oxazinones |
| WO2005092314A1 (en) | 2004-03-18 | 2005-10-06 | Istituto Nazionale Per Lo Studio E La Cura Del Tum | 4-oxo-fenretinide, administered alone and in combination with fenretinide, as preventive and therapeutic agent for cancer |
| WO2011059776A2 (en) * | 2009-10-28 | 2011-05-19 | Revision Therapeutics, Inc | Prophylaxis of skin cancer with retinamides |
-
2015
- 2015-09-16 EP EP15775638.8A patent/EP3194360B1/en active Active
- 2015-09-16 PT PT15775638T patent/PT3194360T/pt unknown
- 2015-09-16 RS RS20180828A patent/RS57443B1/sr unknown
- 2015-09-16 HR HRP20181460TT patent/HRP20181460T1/hr unknown
- 2015-09-16 ES ES15775638.8T patent/ES2686733T3/es active Active
- 2015-09-16 HU HUE15775638A patent/HUE039947T2/hu unknown
- 2015-09-16 US US15/510,798 patent/US10093621B2/en active Active
- 2015-09-16 KR KR1020177006984A patent/KR102547925B1/ko active Active
- 2015-09-16 DK DK15775638.8T patent/DK3194360T3/en active
- 2015-09-16 CN CN201580049384.9A patent/CN107001258B/zh active Active
- 2015-09-16 JP JP2017515241A patent/JP6654771B2/ja active Active
- 2015-09-16 CA CA2961275A patent/CA2961275C/en active Active
- 2015-09-16 WO PCT/EP2015/071178 patent/WO2016042010A1/en not_active Ceased
- 2015-09-16 SI SI201530348T patent/SI3194360T1/sl unknown
- 2015-09-16 AU AU2015316886A patent/AU2015316886B2/en active Active
- 2015-09-16 PL PL15775638T patent/PL3194360T3/pl unknown
-
2018
- 2018-08-27 CY CY20181100888T patent/CY1121920T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107001258A (zh) | 2017-08-01 |
| KR20170076649A (ko) | 2017-07-04 |
| PT3194360T (pt) | 2018-10-18 |
| JP2017533185A (ja) | 2017-11-09 |
| CA2961275A1 (en) | 2016-03-24 |
| HRP20181460T1 (hr) | 2018-11-02 |
| DK3194360T3 (en) | 2018-09-03 |
| ES2686733T3 (es) | 2018-10-19 |
| US10093621B2 (en) | 2018-10-09 |
| HUE039947T2 (hu) | 2019-02-28 |
| KR102547925B1 (ko) | 2023-06-26 |
| AU2015316886A1 (en) | 2017-04-06 |
| WO2016042010A1 (en) | 2016-03-24 |
| RS57443B1 (sr) | 2018-09-28 |
| SI3194360T1 (sl) | 2018-09-28 |
| US20170253560A1 (en) | 2017-09-07 |
| JP6654771B2 (ja) | 2020-02-26 |
| EP3194360A1 (en) | 2017-07-26 |
| CN107001258B (zh) | 2019-03-19 |
| CA2961275C (en) | 2023-10-03 |
| EP3194360B1 (en) | 2018-06-27 |
| AU2015316886B2 (en) | 2019-02-21 |
| CY1121920T1 (el) | 2020-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL266847B (en) | Cancer treatment methods that include tigit binding agents | |
| IL256224B (en) | Combined therapy for cancer treatment | |
| LT3283527T (lt) | Kompleksinė terapija vėžio gydymui | |
| PT3212233T (pt) | Terapia combinada para o tratamento de doenças | |
| SG11201609770TA (en) | Combination therapies for the treatment of cancer | |
| HUE059694T2 (hu) | Készítmény rák kezelésére | |
| IL258521A (en) | Combination of treatments for cancer treatment | |
| IL285077A (en) | Compounds for the treatment of cancer | |
| PL3122358T3 (pl) | Połączenia inhibitorów fgfr i cmet w leczeniu nowotworu | |
| HUE055433T2 (hu) | Kombinált készítmény rák kezelésére | |
| IL259996A (en) | Combinations for cancer treatment | |
| IL249502B (en) | New therapeutic uses of benzylideneguanidine derivatives for the treatment of diseases caused by structurally abnormal proteins | |
| EP3226901A4 (en) | Combination therapy for treatment of cancer | |
| EP3185884A4 (en) | Combination therapy for treatment of cancer | |
| GB201408297D0 (en) | Treatment of cancer | |
| ZA201901578B (en) | Combinations including abx196 for the treatment of cancer | |
| GB201409363D0 (en) | Skin cancer treatment | |
| GB201407837D0 (en) | Methods of cancer therapy | |
| ZA201704589B (en) | Compounds for the treatment of cancer | |
| GB201417456D0 (en) | Treatment of cancer | |
| SI3194360T1 (sl) | 4-okso-N-(4-hidroksifenil)retinamidni derivati kot terapevtska sredstva za zdravljenje raka | |
| SG11201801083UA (en) | Tumor therapeutic agent | |
| GB201417819D0 (en) | Agents for cancer therapy | |
| GB201409362D0 (en) | Treatment of cancer | |
| GB201405449D0 (en) | Treatment of cancer |