PL320916A1 - Derivatives of piperasino 2,5-dione as modulators of drug-fastness in respect to amny drugs - Google Patents
Derivatives of piperasino 2,5-dione as modulators of drug-fastness in respect to amny drugsInfo
- Publication number
- PL320916A1 PL320916A1 PL95320916A PL32091695A PL320916A1 PL 320916 A1 PL320916 A1 PL 320916A1 PL 95320916 A PL95320916 A PL 95320916A PL 32091695 A PL32091695 A PL 32091695A PL 320916 A1 PL320916 A1 PL 320916A1
- Authority
- PL
- Poland
- Prior art keywords
- piperasino
- amny
- fastness
- dione
- modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426224.3A GB9426224D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
| PCT/GB1995/003027 WO1996020190A1 (en) | 1994-12-23 | 1995-12-22 | Piperazine 2,5 dione derivatives as modulators of multi-drug resistance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL320916A1 true PL320916A1 (en) | 1997-11-10 |
Family
ID=10766589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL95320916A PL320916A1 (en) | 1994-12-23 | 1995-12-22 | Derivatives of piperasino 2,5-dione as modulators of drug-fastness in respect to amny drugs |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0799222A1 (en) |
| JP (1) | JPH10511384A (en) |
| CN (1) | CN1175253A (en) |
| AU (1) | AU698828B2 (en) |
| BG (1) | BG101602A (en) |
| BR (1) | BR9510410A (en) |
| CA (1) | CA2207500A1 (en) |
| CZ (1) | CZ190097A3 (en) |
| FI (1) | FI972660L (en) |
| GB (1) | GB9426224D0 (en) |
| HU (1) | HUT77943A (en) |
| IL (1) | IL116525A0 (en) |
| NO (1) | NO972937D0 (en) |
| NZ (1) | NZ297847A (en) |
| PL (1) | PL320916A1 (en) |
| SK (1) | SK83697A3 (en) |
| TW (1) | TW358094B (en) |
| WO (1) | WO1996020190A1 (en) |
| ZA (1) | ZA9510909B (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0001531A3 (en) * | 1996-10-18 | 2000-09-28 | Xenova Ltd Slough | Anthranilic acid derivatives as multi drug resistance modulators |
| GB9717576D0 (en) * | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| CO5140073A1 (en) | 1998-10-08 | 2002-03-22 | Smithkline Beecham Plc | DERIVATIVES OF 2,3,4,5-TETRAHIDRO-1H-3-BENZAPINA |
| BRPI0017067B8 (en) * | 2000-01-18 | 2021-05-25 | Beyondspring Pharmaceuticals Inc | cell division inhibitor, dehydrogenase, method for producing a compound and cell division inhibitor |
| EP1315777B1 (en) | 2000-09-06 | 2007-10-31 | AP Pharma, Inc. | Degradable polyacetal polymers |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| BR0313363A (en) | 2002-08-02 | 2005-08-09 | Nereus Pharmaceuticals Inc | Dehydrophenylhistines and their analogues, and their synthesis |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| CN103396372B (en) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 2,5-diketopiperazine derivative, as well as preparation method and application thereof in preparing control agent for resisting marine fouling organisms |
| MX383691B (en) | 2015-03-06 | 2025-03-14 | Beyondspring Pharmaceuticals Inc | TREATMENT METHOD FOR CANCER ASSOCIATED WITH A RAS MUTATION. |
| HK1249051A1 (en) | 2015-03-06 | 2018-10-26 | BeyondSpring Pharmaceuticals Inc. | Method of treating a brain tumor |
| US10155748B2 (en) | 2015-07-13 | 2018-12-18 | Beyondspring Pharmaceuticals, Inc. | Plinabulin compositions |
| WO2017139231A1 (en) | 2016-02-08 | 2017-08-17 | Beyondspring Pharmaceuticals, Inc. | Compositions containing tucaresol or its analogs |
| RU2760348C2 (en) | 2016-06-06 | 2021-11-24 | Бейондспринг Фармасьютикалс, Инк. | Method for reducing neutropenia |
| JP2020503363A (en) | 2017-01-06 | 2020-01-30 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | Tubulin binding compounds and their therapeutic use |
| BR112019015974A2 (en) | 2017-02-01 | 2020-03-31 | Beyondspring Pharmaceuticals, Inc. | METHOD TO REDUCE NEUTROPENY |
| KR20200112881A (en) | 2018-01-24 | 2020-10-05 | 비욘드스프링 파마수티컬스, 인코포레이티드. | Composition and method for reducing thrombocytopenia through administration of plinabulin |
| CA3215047A1 (en) | 2021-04-09 | 2022-10-13 | Lan Huang | Therapeutic compositions and methods for treating tumors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2718830B2 (en) * | 1992-07-10 | 1998-02-25 | ラボラトワール、グラクソ、ソシエテ、アノニム | Anilide derivative |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426224.3A patent/GB9426224D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510909A patent/ZA9510909B/en unknown
- 1995-12-22 WO PCT/GB1995/003027 patent/WO1996020190A1/en not_active Ceased
- 1995-12-22 IL IL11652595A patent/IL116525A0/en unknown
- 1995-12-22 CA CA002207500A patent/CA2207500A1/en not_active Abandoned
- 1995-12-22 FI FI972660A patent/FI972660L/en unknown
- 1995-12-22 BR BR9510410-0A patent/BR9510410A/en not_active Application Discontinuation
- 1995-12-22 HU HU9800398A patent/HUT77943A/en unknown
- 1995-12-22 CZ CZ971900A patent/CZ190097A3/en unknown
- 1995-12-22 NZ NZ297847A patent/NZ297847A/en unknown
- 1995-12-22 AU AU43100/96A patent/AU698828B2/en not_active Ceased
- 1995-12-22 EP EP95941797A patent/EP0799222A1/en not_active Withdrawn
- 1995-12-22 CN CN95197672A patent/CN1175253A/en active Pending
- 1995-12-22 PL PL95320916A patent/PL320916A1/en unknown
- 1995-12-22 JP JP8520301A patent/JPH10511384A/en active Pending
- 1995-12-22 SK SK836-97A patent/SK83697A3/en unknown
- 1995-12-23 TW TW084113836A patent/TW358094B/en active
-
1997
- 1997-06-11 BG BG101602A patent/BG101602A/en unknown
- 1997-06-23 NO NO972937A patent/NO972937D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI972660A7 (en) | 1997-08-22 |
| CZ190097A3 (en) | 1998-01-14 |
| GB9426224D0 (en) | 1995-02-22 |
| BR9510410A (en) | 1999-09-08 |
| ZA9510909B (en) | 1996-08-30 |
| WO1996020190A1 (en) | 1996-07-04 |
| CA2207500A1 (en) | 1996-07-04 |
| NO972937L (en) | 1997-06-23 |
| SK83697A3 (en) | 1998-05-06 |
| AU4310096A (en) | 1996-07-19 |
| FI972660A0 (en) | 1997-06-19 |
| TW358094B (en) | 1999-05-11 |
| AU698828B2 (en) | 1998-11-05 |
| HUT77943A (en) | 1998-12-28 |
| BG101602A (en) | 1998-02-27 |
| IL116525A0 (en) | 1996-03-31 |
| CN1175253A (en) | 1998-03-04 |
| FI972660L (en) | 1997-08-22 |
| JPH10511384A (en) | 1998-11-04 |
| NZ297847A (en) | 1999-04-29 |
| NO972937D0 (en) | 1997-06-23 |
| EP0799222A1 (en) | 1997-10-08 |
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