PL323638A1 - Method of detecting obesity protein modulating compounds - Google Patents

Method of detecting obesity protein modulating compounds

Info

Publication number: PL323638A1
Authority: PL; Poland
Prior art keywords: modulating compounds; obesity protein; protein modulating; detecting obesity; detecting
Prior art date: 1995-05-30

Application number

PL96323638A

Inventor

Lee James Beeley

Richard Antony Godwin Smith

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-30

Filing date

1996-05-28

Publication date

1998-04-14

1995-05-30 Priority claimed from GBGB9510857.7A external-priority patent/GB9510857D0/en

1995-06-08 Priority claimed from GBGB9511602.6A external-priority patent/GB9511602D0/en

1996-05-28 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1998-04-14 Publication of PL323638A1 publication Critical patent/PL323638A1/en

Links

208000008589 Obesity Diseases 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
235000020824 obesity Nutrition 0.000 title 1
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL96323638A 1995-05-30 1996-05-28 Method of detecting obesity protein modulating compounds PL323638A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9510857.7A GB9510857D0 (en)	1995-05-30	1995-05-30	Novel assay
GBGB9511602.6A GB9511602D0 (en)	1995-06-08	1995-06-08	Novel assay

Publications (1)

Publication Number	Publication Date
PL323638A1 true PL323638A1 (en)	1998-04-14

Family

ID=26307107

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL96323638A PL323638A1 (en)	1995-05-30	1996-05-28	Method of detecting obesity protein modulating compounds

Country Status (15)

Country	Link
EP (1)	EP0832284A1 (en)
JP (1)	JPH11505725A (en)
KR (1)	KR19990022134A (en)
CN (1)	CN1192248A (en)
AU (1)	AU715215B2 (en)
BR (1)	BR9608686A (en)
CA (1)	CA2222409A1 (en)
CZ (1)	CZ379097A3 (en)
HU (1)	HUP9801744A3 (en)
MX (1)	MX9709360A (en)
NO (1)	NO975504D0 (en)
NZ (1)	NZ309777A (en)
PL (1)	PL323638A1 (en)
TR (1)	TR199701469T1 (en)
WO (1)	WO1996038586A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6001968A (en) *	1994-08-17	1999-12-14	The Rockefeller University	OB polypeptides, modified forms and compositions
US6429290B1 (en)	1994-08-17	2002-08-06	The Rockefeller University	OB polypeptides, modified forms and derivatives
EP0914611A4 (en) *	1996-04-22	2002-10-16	Merck & Co Inc	DOSAGE OF LEPTIN
US6007998A (en) *	1996-04-22	1999-12-28	Merck & Co., Inc.	Leptin assay
US6001816A (en) *	1996-06-20	1999-12-14	Merck & Co., Inc.	Gene therapy for leptin deficiency
PL333187A1 (en) *	1996-11-01	1999-11-22	Smithkline Beecham Plc	Method of detecting compounds which modulate the performance of protein of obesity (ob)
IT1293533B1 (en) *	1997-07-14	1999-03-01	Angeletti P Ist Richerche Bio	METHOD FOR THE SELECTION OF MOLECULES ABLE TO MIMIC, INHIBIT OR ENHANCE THE EFFECTS OF THE INTERACTION BETWEEN LEPTIN AND CELLS THAT
WO1999023493A1 (en) *	1997-10-31	1999-05-14	The Rockefeller University	Methods of identifying agents that modulate leptin activity
EP1053007A2 (en) *	1998-02-11	2000-11-22	Beth Israel Deaconess Medical Center	Methods and compositions for modulating leptin activity
GB9814199D0 (en) *	1998-06-30	1998-08-26	Univ Buckingham	Novel method
GB9828087D0 (en) *	1998-12-18	1999-02-17	Smithkline Beecham Plc	Novel method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7795094A (en) *	1993-09-15	1995-04-03	New York University	Dna sequence which binds transcriptional regulatory proteins activated in response to various cytokines and uses thereof
AU2285995A (en) *	1994-04-14	1995-11-10	Ligand Pharmaceuticals Incorporated	Dna spacer regulatory elements responsive to cytokines and methods for their use

1996
- 1996-05-28 PL PL96323638A patent/PL323638A1/en unknown
- 1996-05-28 BR BR9608686A patent/BR9608686A/en active Search and Examination
- 1996-05-28 CA CA002222409A patent/CA2222409A1/en not_active Abandoned
- 1996-05-28 CN CN96195983A patent/CN1192248A/en active Pending
- 1996-05-28 NZ NZ309777A patent/NZ309777A/en unknown
- 1996-05-28 HU HU9801744A patent/HUP9801744A3/en unknown
- 1996-05-28 JP JP8536176A patent/JPH11505725A/en active Pending
- 1996-05-28 EP EP96917454A patent/EP0832284A1/en not_active Withdrawn
- 1996-05-28 CZ CZ973790A patent/CZ379097A3/en unknown
- 1996-05-28 TR TR97/01469T patent/TR199701469T1/en unknown
- 1996-05-28 AU AU60023/96A patent/AU715215B2/en not_active Ceased
- 1996-05-28 MX MX9709360A patent/MX9709360A/en unknown
- 1996-05-28 WO PCT/EP1996/002291 patent/WO1996038586A1/en not_active Ceased
- 1996-05-28 KR KR1019970708613A patent/KR19990022134A/en not_active Ceased
1997
- 1997-11-28 NO NO975504A patent/NO975504D0/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
BR9608686A (en)	1999-07-06
KR19990022134A (en)	1999-03-25
CZ379097A3 (en)	1998-05-13
HUP9801744A2 (en)	1998-10-28
NO975504L (en)	1997-11-28
WO1996038586A1 (en)	1996-12-05
TR199701469T1 (en)	1998-03-21
MX9709360A (en)	1998-02-28
EP0832284A1 (en)	1998-04-01
AU715215B2 (en)	2000-01-20
AU6002396A (en)	1996-12-18
CA2222409A1 (en)	1996-12-05
HUP9801744A3 (en)	2000-06-28
CN1192248A (en)	1998-09-02
NZ309777A (en)	2000-01-28
JPH11505725A (en)	1999-05-25
NO975504D0 (en)	1997-11-28

Publication	Publication Date	Title
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PL323638A1 (en)	1998-04-14	Method of detecting obesity protein modulating compounds
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PL327147A1 (en)	1998-11-23	Method of obtaining dihydropyrimidinones
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HK1009835A (en)	1999-06-11	Method for the detection of compounds that modulate the effects of the obese protein
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