PL326428A1 - Method of obtaining a compound stimulating hormonal secretion of a growth hormone - Google Patents

Method of obtaining a compound stimulating hormonal secretion of a growth hormone

Info

Publication number: PL326428A1
Authority: PL; Poland
Prior art keywords: obtaining; growth hormone; hormonal secretion; compound stimulating; stimulating hormonal
Prior art date: 1995-10-27

Application number

PL96326428A

Inventor

Peter G Houghton

Ioannis Houpis

Audrey Molina

Joseph E Lynch

Ralph P Volante

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-27

Filing date

1996-10-23

Publication date

1998-09-14

1996-02-13 Priority claimed from GBGB9602949.1A external-priority patent/GB9602949D0/en

1996-10-23 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1998-09-14 Publication of PL326428A1 publication Critical patent/PL326428A1/en

Links

102000018997 Growth Hormone Human genes 0.000 title 1
108010051696 Growth Hormone Proteins 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000000122 growth hormone Substances 0.000 title 1
230000003054 hormonal effect Effects 0.000 title 1
230000028327 secretion Effects 0.000 title 1
230000004936 stimulating effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL96326428A 1995-10-27 1996-10-23 Method of obtaining a compound stimulating hormonal secretion of a growth hormone PL326428A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US589895P	1995-10-27	1995-10-27
GBGB9602949.1A GB9602949D0 (en)	1996-02-13	1996-02-13	Process for the preparation of a growth hormone secretagogue
PCT/US1996/016954 WO1997015573A1 (en)	1995-10-27	1996-10-23	Process for the preparation of a growth hormone secretagogue

Publications (1)

Publication Number	Publication Date
PL326428A1 true PL326428A1 (en)	1998-09-14

Family

ID=26308687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL96326428A PL326428A1 (en)	1995-10-27	1996-10-23	Method of obtaining a compound stimulating hormonal secretion of a growth hormone

Country Status (14)

Country	Link
EP (1)	EP0863900A1 (en)
JP (1)	JPH11513984A (en)
KR (1)	KR19990067097A (en)
AR (1)	AR004124A1 (en)
AU (1)	AU7468596A (en)
BR (1)	BR9610887A (en)
CA (1)	CA2235511A1 (en)
CZ (1)	CZ128298A3 (en)
HR (1)	HRP960494A2 (en)
HU (1)	HUP9902095A3 (en)
PL (1)	PL326428A1 (en)
SK (1)	SK51198A3 (en)
WO (1)	WO1997015573A1 (en)
YU (1)	YU56596A (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9601724D0 (en) *	1996-01-29	1996-03-27	Merck Sharp & Dohme	Therapeutic agents
AU4993497A (en) *	1996-10-25	1998-05-22	Merck & Co., Inc.	Convergent process for the preparation of a growth hormone secretagogue
US6329342B1 (en)	1997-08-19	2001-12-11	Eli Lilly And Company	Treatment of congestive heart failure with growth hormone secretagogues
US6639076B1 (en)	1998-08-18	2003-10-28	Eli Lilly And Company	Growth hormone secretagogues
US6828331B1 (en)	1999-02-19	2004-12-07	Eli Lilly And Company	Growth hormone secretagogues
ATE446758T1 (en)	2000-05-31	2009-11-15	Pfizer Prod Inc	USE OF GROWTH HORMONE SECRETAGOGENES TO PROMOTE DIGESTIVE MOTILITY
US7125840B2 (en)	2001-10-09	2006-10-24	Eli Lilly And Company	Substituted dipeptides as growth hormone secretagogues
WO2003087069A2 (en)	2002-04-09	2003-10-23	Eli Lilly And Company	Dipeptidic growth hormone secretagogues
US7476653B2 (en)	2003-06-18	2009-01-13	Tranzyme Pharma, Inc.	Macrocyclic modulators of the ghrelin receptor
CU23558A1 (en)	2006-02-28	2010-07-20	Ct Ingenieria Genetica Biotech	COMPOUNDS ANALOG TO THE PEPTIDIC SECRETAGOGS OF THE GROWTH HORMONE
CA2677399C (en)	2007-02-09	2016-09-13	Tranzyme Pharma, Inc.	Macrocyclic ghrelin receptor modulators and methods of using the same
US9119832B2 (en)	2014-02-05	2015-09-01	The Regents Of The University Of California	Methods of treating mild brain injury
WO2017075535A1 (en)	2015-10-28	2017-05-04	Oxeia Biopharmaceuticals, Inc.	Methods of treating neurodegenerative conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994013696A1 (en) *	1992-12-11	1994-06-23	Merck & Co., Inc.	Spiro piperidines and homologs which promote release of growth hormone

1996
- 1996-10-23 WO PCT/US1996/016954 patent/WO1997015573A1/en not_active Ceased
- 1996-10-23 CA CA002235511A patent/CA2235511A1/en not_active Abandoned
- 1996-10-23 PL PL96326428A patent/PL326428A1/en unknown
- 1996-10-23 SK SK511-98A patent/SK51198A3/en unknown
- 1996-10-23 BR BR9610887A patent/BR9610887A/en not_active Application Discontinuation
- 1996-10-23 AU AU74685/96A patent/AU7468596A/en not_active Abandoned
- 1996-10-23 JP JP9516736A patent/JPH11513984A/en active Pending
- 1996-10-23 CZ CZ981282A patent/CZ128298A3/en unknown
- 1996-10-23 HU HU9902095A patent/HUP9902095A3/en unknown
- 1996-10-23 EP EP96936868A patent/EP0863900A1/en not_active Withdrawn
- 1996-10-23 KR KR1019980703037A patent/KR19990067097A/en not_active Withdrawn
- 1996-10-25 HR HR9602949.1A patent/HRP960494A2/en not_active Application Discontinuation
- 1996-10-25 YU YU56596A patent/YU56596A/en unknown
- 1996-10-25 AR ARP960104931A patent/AR004124A1/en unknown

Also Published As

Publication number	Publication date
JPH11513984A (en)	1999-11-30
EP0863900A1 (en)	1998-09-16
MX9803316A (en)	1998-09-30
AR004124A1 (en)	1998-09-30
HRP960494A2 (en)	1998-04-30
SK51198A3 (en)	1998-11-04
WO1997015573A1 (en)	1997-05-01
HUP9902095A3 (en)	2001-05-28
BR9610887A (en)	1999-07-13
YU56596A (en)	1999-09-27
CZ128298A3 (en)	1998-07-15
HUP9902095A2 (en)	1999-10-28
KR19990067097A (en)	1999-08-16
CA2235511A1 (en)	1997-05-01
AU7468596A (en)	1997-05-15

Publication	Publication Date	Title
PL327634A1 (en)	1998-12-21	Growth hormone secretion stimulating compounds
HUP9900870A3 (en)	2001-04-28	Composition for sustained release of human growth hormone
ZA968989B (en)	1997-04-29	Polymorphic forms of a growth hormone secretagogue
PL321590A1 (en)	1997-12-08	Compounds capable to cause liberation of the growth hormone
AU1868595A (en)	1995-08-15	Human growth hormone
AU2147192A (en)	1993-01-25	Method of stimulating immune response using growth hormone
AU1615695A (en)	1995-10-19	Method for forming bone cement to an implant
IL116743A0 (en)	1996-05-14	Pharmaceutical composition comprising a growth hormone
AU3964795A (en)	1996-05-23	4-heterocyclic piperidines promote release of growth hormone
GB9622440D0 (en)	1997-01-08	Treatment of congestive heart failure with a growth hormone secretagogue
PL356364A1 (en)	2003-04-07	Application of growth hormone secretion stimulating compound and a set therefor
HUP9902095A3 (en)	2001-05-28	New process for the preparation of a growth hormone secretagogue
AU5514586A (en)	1986-08-26	A process for producing human growth hormone
GB9602414D0 (en)	1996-04-03	Camphor compounds promote release of growth hormone
IL116201A0 (en)	1996-01-31	Method of preparing confections
AU1942995A (en)	1995-10-03	New use of growth hormone
AU4993497A (en)	1998-05-22	Convergent process for the preparation of a growth hormone secretagogue
PL327511A1 (en)	1998-12-21	Polymorphous forms of a growth hormone secretion stimulating substance
AU6046294A (en)	1994-09-14	Process for producing human growth hormone
EP0828507A4 (en)	2000-10-18	Method for treatment of pain
IL116742A0 (en)	1996-05-14	Pharmaceutical composition comprising a growth hormone
KR0184754B1 (en)	1999-04-01	Method for producing human growth hormone
AU5881996A (en)	1996-12-30	Methods of treatment using growth hormone antagonists
AU4659196A (en)	1996-07-31	Methods of inhibiting growth hormone effects
AU1267992A (en)	1993-08-03	Method of installing a dental implant