PL326844A1 - Novel derivatives of quinosalinodione, their production and implementation in drugs - Google Patents

Novel derivatives of quinosalinodione, their production and implementation in drugs

Info

Publication number
PL326844A1
PL326844A1 PL96326844A PL32684496A PL326844A1 PL 326844 A1 PL326844 A1 PL 326844A1 PL 96326844 A PL96326844 A PL 96326844A PL 32684496 A PL32684496 A PL 32684496A PL 326844 A1 PL326844 A1 PL 326844A1
Authority
PL
Poland
Prior art keywords
quinosalinodione
drugs
implementation
production
novel derivatives
Prior art date
Application number
PL96326844A
Other languages
English (en)
Inventor
Andreas Huth
Martin Krueger
Eckhard Ottow
Dieter Seidelmann
Roland Neuhaus
Herbert Schneider
Lechoslaw Turski
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PL326844A1 publication Critical patent/PL326844A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994—Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL96326844A 1995-11-24 1996-11-15 Novel derivatives of quinosalinodione, their production and implementation in drugs PL326844A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19545251A DE19545251A1 (de) 1995-11-24 1995-11-24 Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
PCT/DE1996/002227 WO1997019066A1 (de) 1995-11-24 1996-11-15 Neue chinoxalindionderivate, deren herstellung und verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
PL326844A1 true PL326844A1 (en) 1998-10-26

Family

ID=7779176

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96326844A PL326844A1 (en) 1995-11-24 1996-11-15 Novel derivatives of quinosalinodione, their production and implementation in drugs

Country Status (20)

Country Link
EP (1) EP0876357A1 (is)
JP (1) JP2000500471A (is)
KR (1) KR19990071596A (is)
CN (1) CN1202891A (is)
AU (1) AU720083B2 (is)
CA (1) CA2238023A1 (is)
CZ (1) CZ160498A3 (is)
DE (1) DE19545251A1 (is)
EE (1) EE9800163A (is)
HU (1) HUP9902041A3 (is)
IL (1) IL124534A0 (is)
IS (1) IS4740A (is)
MX (1) MX9804068A (is)
NO (1) NO982349L (is)
NZ (1) NZ330492A (is)
PL (1) PL326844A1 (is)
SK (1) SK68298A3 (is)
TR (1) TR199800904T2 (is)
WO (1) WO1997019066A1 (is)
ZA (1) ZA969832B (is)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737446A1 (de) * 1997-08-22 1999-02-25 Schering Ag Verfahren zur Herstellung von Phosphonsäurederivaten
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CN106619953A (zh) * 2016-10-31 2017-05-10 山东省海盟生化科技有限公司 一种用于皮肤病的外用中药组合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
PT101004B (pt) * 1991-10-26 1999-10-29 Schering Ag Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4439492A1 (de) * 1994-10-25 1996-05-02 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
DE4439493A1 (de) * 1994-10-25 1996-05-02 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
DE19519979A1 (de) * 1995-05-24 1996-11-28 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln

Also Published As

Publication number Publication date
EP0876357A1 (de) 1998-11-11
HUP9902041A2 (hu) 2000-04-28
ZA969832B (en) 1997-06-17
IL124534A0 (en) 1998-12-06
MX9804068A (es) 1998-09-30
SK68298A3 (en) 1998-12-02
DE19545251A1 (de) 1997-05-28
CN1202891A (zh) 1998-12-23
HUP9902041A3 (en) 2000-07-28
AU1867497A (en) 1997-06-11
EE9800163A (et) 1998-12-15
JP2000500471A (ja) 2000-01-18
NO982349L (no) 1998-07-01
IS4740A (is) 1998-05-13
KR19990071596A (ko) 1999-09-27
TR199800904T2 (xx) 1998-08-21
CA2238023A1 (en) 1997-05-29
NZ330492A (en) 1999-10-28
AU720083B2 (en) 2000-05-25
CZ160498A3 (cs) 1998-09-16
WO1997019066A1 (de) 1997-05-29
NO982349D0 (no) 1998-05-22

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PL326844A1 (en) Novel derivatives of quinosalinodione, their production and implementation in drugs