PL3272745T3 - Podstawione imidazolilem pochodne indolu wiążące receptor serotoninowy 5-HT7 oraz ich kompozycje farmaceutyczne - Google Patents

Podstawione imidazolilem pochodne indolu wiążące receptor serotoninowy 5-HT7 oraz ich kompozycje farmaceutyczne

Info

Publication number
PL3272745T3
PL3272745T3 PL16461543T PL16461543T PL3272745T3 PL 3272745 T3 PL3272745 T3 PL 3272745T3 PL 16461543 T PL16461543 T PL 16461543T PL 16461543 T PL16461543 T PL 16461543T PL 3272745 T3 PL3272745 T3 PL 3272745T3
Authority
PL
Poland
Prior art keywords
imidazolyl
pharmaceutical compositions
serotonin receptor
indole derivatives
substituted indole
Prior art date
Application number
PL16461543T
Other languages
English (en)
Inventor
Adam Hogendorf
Agata Hogendorf
Grzegorz Satala
Rafal Kurczab
Ryszard Bugno
Jakub Staron
Tomasz Lenda
Andrzej J. BOJARSKI
Original Assignee
Instytut Farmakologii Polskiej Akademii Nauk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Farmakologii Polskiej Akademii Nauk filed Critical Instytut Farmakologii Polskiej Akademii Nauk
Publication of PL3272745T3 publication Critical patent/PL3272745T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL16461543T 2016-07-21 2016-07-21 Podstawione imidazolilem pochodne indolu wiążące receptor serotoninowy 5-HT7 oraz ich kompozycje farmaceutyczne PL3272745T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16461543.7A EP3272745B1 (en) 2016-07-21 2016-07-21 Imidazolyl-substituted indole derivatives binding 5-ht7 serotonin receptor and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
PL3272745T3 true PL3272745T3 (pl) 2020-01-31

Family

ID=56507560

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16461543T PL3272745T3 (pl) 2016-07-21 2016-07-21 Podstawione imidazolilem pochodne indolu wiążące receptor serotoninowy 5-HT7 oraz ich kompozycje farmaceutyczne

Country Status (12)

Country Link
US (1) US10844046B2 (pl)
EP (1) EP3272745B1 (pl)
CN (1) CN109641877B (pl)
AU (1) AU2017300841B2 (pl)
CA (1) CA3031006A1 (pl)
DK (1) DK3272745T3 (pl)
ES (1) ES2744720T3 (pl)
HR (1) HRP20191532T1 (pl)
HU (1) HUE045355T2 (pl)
PL (1) PL3272745T3 (pl)
PT (1) PT3272745T (pl)
WO (1) WO2018015558A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11572354B2 (en) 2018-01-10 2023-02-07 University Health Network Inhibitor of indoleamine 2,3-dioxygenase-1 and methods of manufacture and use thereof
CN112174937B (zh) * 2020-10-19 2022-06-03 南京农业大学 3-(5-咪唑基)吲哚类化合物及其制备方法和应用
US20230391786A1 (en) * 2022-06-02 2023-12-07 Eli Lilly And Company cGAS INHIBITORS
PL447976A1 (pl) * 2024-03-11 2025-09-15 Celon Pharma Spółka Akcyjna Pochodna imidazolo-indolowa wiążąca się z receptorem serotoninowym 5-HT7, kompozycja farmaceutyczna zawierająca tę pochodną, zastosowania pochodnej i kompozycji oraz produkt pośredni do wytwarzania pochodnej imidazolo-indolowej

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616601A (en) * 1994-07-28 1997-04-01 Gd Searle & Co 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
DE19948417A1 (de) 1999-10-07 2001-04-19 Morphochem Ag Imidazol-Derivate und ihre Verwendung als Arzneimittel
US6281356B1 (en) * 1999-12-22 2001-08-28 Hoffmann-La Roche Inc. Substituted pyrroles
EP2142535A2 (en) * 2007-03-29 2010-01-13 Novartis Ag 3-imidazolyl-indoles for the treatment of proliferative diseases

Also Published As

Publication number Publication date
ES2744720T3 (es) 2020-02-26
PT3272745T (pt) 2019-09-27
AU2017300841A1 (en) 2019-01-31
AU2017300841B2 (en) 2021-09-09
CN109641877B (zh) 2021-09-21
CA3031006A1 (en) 2018-01-25
EP3272745B1 (en) 2019-06-26
US10844046B2 (en) 2020-11-24
CN109641877A (zh) 2019-04-16
DK3272745T3 (da) 2019-09-02
EP3272745A1 (en) 2018-01-24
WO2018015558A1 (en) 2018-01-25
HUE045355T2 (hu) 2019-12-30
US20190284169A1 (en) 2019-09-19
HRP20191532T1 (hr) 2019-11-29

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