PL3273968T3 - Związki minocykliny do ochrony biologicznej - Google Patents

Związki minocykliny do ochrony biologicznej

Info

Publication number
PL3273968T3
PL3273968T3 PL16769622.8T PL16769622T PL3273968T3 PL 3273968 T3 PL3273968 T3 PL 3273968T3 PL 16769622 T PL16769622 T PL 16769622T PL 3273968 T3 PL3273968 T3 PL 3273968T3
Authority
PL
Poland
Prior art keywords
biodefense
minocycline compounds
minocycline
compounds
Prior art date
Application number
PL16769622.8T
Other languages
English (en)
Inventor
Michael P. Draper
S. Ken Tanaka
Original Assignee
Paratek Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharmaceuticals, Inc. filed Critical Paratek Pharmaceuticals, Inc.
Publication of PL3273968T3 publication Critical patent/PL3273968T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL16769622.8T 2015-03-24 2016-03-23 Związki minocykliny do ochrony biologicznej PL3273968T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562137719P 2015-03-24 2015-03-24
PCT/US2016/023807 WO2016154332A1 (en) 2015-03-24 2016-03-23 Minocycline compounds for biodefense

Publications (1)

Publication Number Publication Date
PL3273968T3 true PL3273968T3 (pl) 2024-01-03

Family

ID=56977663

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16769622.8T PL3273968T3 (pl) 2015-03-24 2016-03-23 Związki minocykliny do ochrony biologicznej

Country Status (14)

Country Link
US (5) US20180133231A1 (pl)
EP (2) EP3273968B1 (pl)
JP (4) JP6826582B2 (pl)
KR (3) KR102656263B1 (pl)
CN (2) CN107613988A (pl)
AU (4) AU2016235151A1 (pl)
CA (1) CA2980727C (pl)
ES (1) ES2959665T3 (pl)
FI (1) FI3273968T3 (pl)
HU (1) HUE063795T2 (pl)
IL (1) IL254622B2 (pl)
MX (1) MX389771B (pl)
PL (1) PL3273968T3 (pl)
WO (1) WO2016154332A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL254622B2 (en) * 2015-03-24 2024-01-01 Paratek Minocycline compounds for biodefense
JP7025702B2 (ja) * 2016-03-31 2022-02-25 日産化学株式会社 配向層形成組成物
TW202206081A (zh) * 2016-08-03 2022-02-16 美商派瑞泰Spv2有限公司 9—胺甲基米諾四環素化合物及其用途
BR112019008897A2 (pt) * 2016-11-01 2019-08-13 Paratek Pharm Innc método para tratar pneumonia bacteriana adquirida na comunidade.
WO2019212883A1 (en) * 2018-04-30 2019-11-07 Rempex Pharmaceuticals, Inc. Methods of treating bacterial infections with minocycline
SG11202106791XA (en) 2019-01-31 2021-07-29 Takeda Pharmaceuticals Co Heterocyclic compound and use thereof
CN111484424B (zh) * 2020-04-14 2022-10-25 成都百特万合医药科技有限公司 一种合成奥马环素的方法
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas
CN114591216A (zh) * 2022-02-17 2022-06-07 四川澄华生物科技有限公司 一种合成奥马环素中间体的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA013908B1 (ru) 2000-07-07 2010-08-30 Трастис Оф Тафтс Коллидж Замещенные соединения миноциклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния млекопитающего
WO2011101710A1 (en) * 2010-02-16 2011-08-25 Wockhardt Research Centre Efflux pump inhibitors
US7553828B2 (en) 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
WO2003082011A1 (en) * 2002-03-29 2003-10-09 The Research Foundation Of State University Of New York Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins
US7943600B2 (en) 2004-12-20 2011-05-17 Massachusetts Institute Of Technology Antimicrobial combination therapy
JP2009526069A (ja) * 2006-02-08 2009-07-16 バイオシネクサス インコーポレーティッド 細菌胞子の中和
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
JP2010525069A (ja) 2007-04-27 2010-07-22 パラテック ファーマシューティカルズ インコーポレイテッド アミノアルキルテトラサイクリン化合物の合成方法および精製方法
CA2717703A1 (en) 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
AU2013262991A1 (en) * 2012-05-14 2014-12-04 Paratek Pharmaceuticals, Inc. Methods of using (4S,4aS,5aR,12aS)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide
IL254622B2 (en) 2015-03-24 2024-01-01 Paratek Minocycline compounds for biodefense

Also Published As

Publication number Publication date
IL254622B1 (en) 2023-09-01
ES2959665T3 (es) 2024-02-27
EP3273968B1 (en) 2023-07-19
EP3273968A1 (en) 2018-01-31
AU2016235151A1 (en) 2017-10-12
JP2021059544A (ja) 2021-04-15
HUE063795T2 (hu) 2024-01-28
FI3273968T3 (fi) 2023-10-09
AU2020260450B2 (en) 2022-07-21
IL254622B2 (en) 2024-01-01
KR20240051297A (ko) 2024-04-19
CN116392496A (zh) 2023-07-07
KR102656263B1 (ko) 2024-04-09
US20250367219A1 (en) 2025-12-04
IL254622A0 (en) 2017-11-30
JP2025023946A (ja) 2025-02-19
US11129839B2 (en) 2021-09-28
KR20170138439A (ko) 2017-12-15
AU2020260450A1 (en) 2020-12-03
CA2980727A1 (en) 2016-09-29
AU2022256106A1 (en) 2022-11-24
MX389771B (es) 2025-03-20
JP2018509475A (ja) 2018-04-05
EP4268897A3 (en) 2024-01-03
JP6826582B2 (ja) 2021-02-03
US20200330489A1 (en) 2020-10-22
US20230098554A1 (en) 2023-03-30
US20240238315A1 (en) 2024-07-18
EP4268897A2 (en) 2023-11-01
MX2017012073A (es) 2018-02-21
WO2016154332A1 (en) 2016-09-29
US20180133231A1 (en) 2018-05-17
AU2024202788A1 (en) 2024-05-23
KR20250151591A (ko) 2025-10-21
CN107613988A (zh) 2018-01-19
CA2980727C (en) 2023-09-19
JP2023022179A (ja) 2023-02-14
EP3273968A4 (en) 2018-11-14

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