PL3287443T3 - 6-członowa pochodna heterocykliczna i kompozycja farmaceutyczna ją zawierająca - Google Patents
6-członowa pochodna heterocykliczna i kompozycja farmaceutyczna ją zawierającaInfo
- Publication number
- PL3287443T3 PL3287443T3 PL16783270T PL16783270T PL3287443T3 PL 3287443 T3 PL3287443 T3 PL 3287443T3 PL 16783270 T PL16783270 T PL 16783270T PL 16783270 T PL16783270 T PL 16783270T PL 3287443 T3 PL3287443 T3 PL 3287443T3
- Authority
- PL
- Poland
- Prior art keywords
- same
- pharmaceutical composition
- membered heterocyclic
- heterocyclic derivative
- derivative
- Prior art date
Links
- 125000004070 6 membered heterocyclic group Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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| US10392347B2 (en) | 2015-10-14 | 2019-08-27 | Bristol-Myers Squibb Company | 2,4-dihydroxy-nicotinamides as APJ agonists |
| MY189454A (en) | 2016-03-24 | 2022-02-14 | Bristol Myers Squibb Co | 6-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamides as apj agonists |
| WO2017204316A1 (ja) * | 2016-05-27 | 2017-11-30 | 塩野義製薬株式会社 | 5-オキソ-1,2,4-トリアジン誘導体およびその医薬組成物 |
| EP3527568A4 (en) | 2016-10-17 | 2020-03-18 | Shionogi & Co., Ltd | BICYCLIC NITROGENATED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREFOR |
| WO2018074565A1 (ja) * | 2016-10-21 | 2018-04-26 | 塩野義製薬株式会社 | 含窒素6員複素環誘導体およびそれらを含有する医薬組成物 |
| WO2020132820A1 (zh) * | 2018-12-24 | 2020-07-02 | 广东莱佛士制药技术有限公司 | 一种3-(苄氧基)-4-氧代-4h-吡喃-2-羧酸的合成方法 |
| CN113666914B (zh) * | 2021-09-27 | 2022-06-07 | 成都施贝康生物医药科技有限公司 | 二氢嘧啶类化合物及其制备方法和用途 |
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| WO1999024420A1 (en) * | 1997-11-06 | 1999-05-20 | Smithkline Beecham Plc | Pyrimidinone compounds and pharmaceutical compositions containing them |
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| PA8557501A1 (es) | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| JP2005530806A (ja) * | 2002-05-23 | 2005-10-13 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害薬 |
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| CN1980902A (zh) * | 2004-06-29 | 2007-06-13 | 辉瑞产品有限公司 | 通过对羟基保护前体去保护而制备5-4-(2-羟基-丙基)-3,5-二氧代-4,5-二氢-3h-[1,2,4]三嗪-2-基-苯甲酰胺衍生物的方法 |
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-
2016
- 2016-04-22 JP JP2017514205A patent/JP6358639B2/ja active Active
- 2016-04-22 DK DK16783270.8T patent/DK3287443T3/da active
- 2016-04-22 PL PL16783270T patent/PL3287443T3/pl unknown
- 2016-04-22 EP EP21196697.3A patent/EP3957627B1/en active Active
- 2016-04-22 KR KR1020197031631A patent/KR20190123812A/ko not_active Withdrawn
- 2016-04-22 BR BR112017022654-5A patent/BR112017022654A2/pt not_active Application Discontinuation
- 2016-04-22 CA CA2983721A patent/CA2983721A1/en not_active Abandoned
- 2016-04-22 WO PCT/JP2016/062759 patent/WO2016171249A1/ja not_active Ceased
- 2016-04-22 EP EP16783270.8A patent/EP3287443B1/en active Active
- 2016-04-22 ES ES16783270T patent/ES2905399T3/es active Active
- 2016-04-22 AU AU2016252686A patent/AU2016252686B2/en not_active Ceased
- 2016-04-22 KR KR1020177033887A patent/KR102059333B1/ko not_active Expired - Fee Related
- 2016-04-22 RU RU2017140830A patent/RU2683245C1/ru active
- 2016-04-22 CN CN201680037127.8A patent/CN107709299B/zh active Active
- 2016-04-22 TW TW105112745A patent/TWI715569B/zh not_active IP Right Cessation
- 2016-04-22 MX MX2017013678A patent/MX391647B/es unknown
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2018
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2020
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Also Published As
| Publication number | Publication date |
|---|---|
| US11124486B2 (en) | 2021-09-21 |
| WO2016171249A1 (ja) | 2016-10-27 |
| DK3287443T3 (da) | 2022-02-07 |
| KR20170139144A (ko) | 2017-12-18 |
| US20200262796A1 (en) | 2020-08-20 |
| BR112017022654A2 (pt) | 2018-07-10 |
| US10774051B2 (en) | 2020-09-15 |
| JPWO2016171249A1 (ja) | 2018-03-01 |
| JP6358639B2 (ja) | 2018-07-18 |
| EP3287443B1 (en) | 2021-10-27 |
| TWI715569B (zh) | 2021-01-11 |
| US20180118694A1 (en) | 2018-05-03 |
| KR20190123812A (ko) | 2019-11-01 |
| RU2683245C1 (ru) | 2019-03-27 |
| EP3287443A1 (en) | 2018-02-28 |
| JP2018162273A (ja) | 2018-10-18 |
| EP3957627B1 (en) | 2024-06-19 |
| AU2016252686A1 (en) | 2017-10-26 |
| CN107709299B (zh) | 2021-07-16 |
| TW201643140A (zh) | 2016-12-16 |
| EP3957627A1 (en) | 2022-02-23 |
| CA2983721A1 (en) | 2016-10-27 |
| AU2016252686B2 (en) | 2019-03-14 |
| ES2905399T3 (es) | 2022-04-08 |
| US20210292283A1 (en) | 2021-09-23 |
| MX2017013678A (es) | 2018-03-15 |
| KR102059333B1 (ko) | 2019-12-26 |
| CN107709299A (zh) | 2018-02-16 |
| EP3287443A4 (en) | 2018-09-26 |
| MX391647B (es) | 2025-03-21 |
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