PL329351A1 - Piperidines and pyrolydines - Google Patents

Piperidines and pyrolydines

Info

Publication number
PL329351A1
PL329351A1 PL97329351A PL32935197A PL329351A1 PL 329351 A1 PL329351 A1 PL 329351A1 PL 97329351 A PL97329351 A PL 97329351A PL 32935197 A PL32935197 A PL 32935197A PL 329351 A1 PL329351 A1 PL 329351A1
Authority
PL
Poland
Prior art keywords
pyrolydines
piperidines
Prior art date
Application number
PL97329351A
Inventor
Joachim Maerz
Henning Boettcher
Ralf Devant
Hartmut Greiner
Gerd Bartoszyk
Juergen Harting
Christoph Seyfried
Ronny Andersson Bengt
Lars Olov Hansson
Clas Ake Sonesson
Nils Peter Stjernloef
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL329351A1 publication Critical patent/PL329351A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
PL97329351A 1996-04-18 1997-04-14 Piperidines and pyrolydines PL329351A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19615232A DE19615232A1 (en) 1996-04-18 1996-04-18 New carbamoyl derivatives and their use as 5-HT ¶1¶¶A¶ antagonists
PCT/EP1997/001853 WO1997040038A1 (en) 1996-04-18 1997-04-14 Piperidines and pyrrolidines

Publications (1)

Publication Number Publication Date
PL329351A1 true PL329351A1 (en) 1999-03-29

Family

ID=7791576

Family Applications (1)

Application Number Title Priority Date Filing Date
PL97329351A PL329351A1 (en) 1996-04-18 1997-04-14 Piperidines and pyrolydines

Country Status (15)

Country Link
EP (1) EP0898569A1 (en)
JP (1) JP2000508670A (en)
KR (1) KR20000005505A (en)
AR (1) AR006690A1 (en)
AU (1) AU2696797A (en)
BR (1) BR9708677A (en)
CA (1) CA2252385A1 (en)
CZ (1) CZ330598A3 (en)
DE (1) DE19615232A1 (en)
HU (1) HUP9901389A3 (en)
NO (1) NO984861D0 (en)
PL (1) PL329351A1 (en)
SK (1) SK141998A3 (en)
WO (1) WO1997040038A1 (en)
ZA (1) ZA973301B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19756036A1 (en) * 1997-12-17 1999-06-24 Merck Patent Gmbh New indole amide derivatives
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
DK1068199T3 (en) * 1998-04-08 2003-03-03 Wyeth Corp N-Aryloxyethyl indolylalkylamines for the treatment of depression
AR015035A1 (en) * 1998-04-29 2001-04-11 American Home Prod SEROTONERGIC AGENTS, PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM AND ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT
US6376494B1 (en) 1998-06-15 2002-04-23 American Home Products Corporation Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents
WO1999065887A1 (en) * 1998-06-15 1999-12-23 American Home Products Corporation Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents
CN1335835A (en) * 1998-12-17 2002-02-13 美国家用产品公司 Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine urea derivatives having 5HT1A receptor activity
DE69925160T2 (en) * 1998-12-17 2006-02-16 Wyeth ARYLPIPERIDINE AND ARYL 1,2,5,6-TETRAHYDROPYRIDINAMIDE DERIVATIVES WITH 5HT1A RECEPTOR ACTIVITY
US6239126B1 (en) 1998-12-17 2001-05-29 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetra-hydropyridine urea derivatives
US6326381B1 (en) 1998-12-17 2001-12-04 American Home Products Corporation Arylpiperidine and aryl-1,2,5,6-tetrahydropyidine amide derivates
EP1146871A4 (en) * 1999-01-28 2002-04-17 Bristol Myers Squibb Co Antidepressant heterocyclic compounds
BR0116549A (en) * 2000-12-27 2003-12-23 Axiogenesis Ag System for cell-specific selection and development-specific selection of embryonic stem cell, adult stem cell and germ line embryonic cell differentiation
KR100459917B1 (en) * 2001-12-14 2004-12-03 (주)바이오뉴트리젠 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising same
DE10337184A1 (en) * 2003-08-13 2005-03-10 Gruenenthal Gmbh Substituted 3-pyrrolidine-indole derivatives
UY36390A (en) * 2014-11-05 2016-06-01 Flexus Biosciences Inc MODULATING COMPOUNDS OF INDOLAMINE ENZYME 2,3-DIOXYGENASE (IDO), ITS SYNTHESIS METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EA201790806A1 (en) 2014-11-05 2017-11-30 Флексус Байосайенсиз, Инк. IMMUNOREGULATING AGENTS
KR20240017363A (en) * 2021-06-02 2024-02-07 세인트 조셉스 유니버시티 Fluorinated tryptamine compounds, analogs thereof and methods of using the same
KR20240144259A (en) 2022-01-29 2024-10-02 수벤 라이프 사이언시스 리미티드 Benzoisothiazole and benzoxazole compounds for the treatment of mental disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3226392A (en) * 1960-03-07 1965-12-28 Sterling Drug Inc 1-[n-aryl-n-acylaminoalkyl]-4-aryl-1,2,3,6-tetrahydropyridines, the corresponding piperidines and their salts
US3647790A (en) * 1969-04-08 1972-03-07 American Home Prod Ouinoxalinyl-oxazolidines and -oxazines
US4782071A (en) * 1986-11-03 1988-11-01 Warner-Lambert Company Tetrasubstituted urea cholinergic agents
MX9201991A (en) * 1991-05-02 1992-11-01 Jonh Wyeth & Brother Limited DERIVATIVES OF PIPERAZINE AND PROCEDURE FOR ITS PREPARATION.
FR2706894A1 (en) * 1993-06-22 1994-12-30 Synthelabo N-Phenyl-N-(piperidinoalkyl)arylamide derivatives, their preparation and their application in therapeutics
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
GB9411099D0 (en) * 1994-06-03 1994-07-27 Wyeth John & Brother Ltd Piperazine derivatives

Also Published As

Publication number Publication date
NO984861L (en) 1998-10-16
AR006690A1 (en) 1999-09-08
NO984861D0 (en) 1998-10-16
CA2252385A1 (en) 1997-10-30
KR20000005505A (en) 2000-01-25
EP0898569A1 (en) 1999-03-03
AU2696797A (en) 1997-11-12
BR9708677A (en) 1999-08-03
HUP9901389A3 (en) 2000-09-28
CZ330598A3 (en) 1999-01-13
WO1997040038A1 (en) 1997-10-30
JP2000508670A (en) 2000-07-11
SK141998A3 (en) 1999-03-12
HUP9901389A2 (en) 1999-08-30
DE19615232A1 (en) 1997-10-23
ZA973301B (en) 1997-10-24

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