PL3294740T3 - Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych - Google Patents

Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych

Info

Publication number: PL3294740T3
Authority: PL; Poland
Prior art keywords: prophylaxis; derivatives; novel; treatment; virus infection
Prior art date: 2015-05-08

Application number

PL16720421T

Other languages

English (en)

Inventor

Chungen Liang

Kun MIAO

Jianping Wang

Hongying Yun

Xiufang ZHENG

Original Assignee

F. Hoffmann-La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-05-08

Filing date

2016-05-04

Publication date

2020-03-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55910966&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3294740(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-05-04 Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag

2020-03-31 Publication of PL3294740T3 publication Critical patent/PL3294740T3/pl

Links

150000001875 compounds Chemical class 0.000 title 1
238000011321 prophylaxis Methods 0.000 title 1
238000011282 treatment Methods 0.000 title 1
230000009385 viral infection Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL16720421T 2015-05-08 2016-05-04 Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych PL3294740T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
CN2015078507		2015-05-08
CN2016078785		2016-04-08
PCT/EP2016/059961 WO2016180695A1 (en)	2015-05-08	2016-05-04	Novel sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection
EP16720421.3A EP3294740B1 (en)	2015-05-08	2016-05-04	Novel sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection

Publications (1)

Publication Number	Publication Date
PL3294740T3 true PL3294740T3 (pl)	2020-03-31

Family

ID=55910966

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL16720421T PL3294740T3 (pl)	2015-05-08	2016-05-04	Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych

Country Status (32)

Country	Link
US (3)	US9708325B2 (pl)
EP (1)	EP3294740B1 (pl)
JP (1)	JP6738352B2 (pl)
KR (1)	KR102690131B1 (pl)
CN (1)	CN107580596B (pl)
AR (1)	AR104528A1 (pl)
AU (3)	AU2016260683B2 (pl)
BR (1)	BR112017023959B1 (pl)
CA (1)	CA2982704C (pl)
CL (1)	CL2017002745A1 (pl)
CO (1)	CO2017009994A2 (pl)
CR (1)	CR20170496A (pl)
DK (1)	DK3294740T3 (pl)
ES (1)	ES2753777T3 (pl)
HR (1)	HRP20191942T1 (pl)
HU (1)	HUE045906T2 (pl)
IL (2)	IL254947B (pl)
LT (1)	LT3294740T (pl)
MX (2)	MX376761B (pl)
MY (1)	MY182353A (pl)
NZ (2)	NZ735648A (pl)
PE (1)	PE20171620A1 (pl)
PH (1)	PH12017502009A1 (pl)
PL (1)	PL3294740T3 (pl)
PT (1)	PT3294740T (pl)
RS (1)	RS59435B1 (pl)
RU (1)	RU2745269C2 (pl)
SG (1)	SG10202108841YA (pl)
SI (1)	SI3294740T1 (pl)
TW (2)	TWI768467B (pl)
UA (1)	UA120450C2 (pl)
WO (1)	WO2016180695A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX376761B (es)	2015-05-08	2025-03-07	Hoffmann La Roche	Nuevos compuestos y derivados de sulfonimidoilpurinona para el tratamiento y profilaxis de infecciones víricas.
KR102459155B1 (ko) *	2016-08-29	2022-10-28	에프. 호프만-라 로슈 아게	바이러스 감염의 치료 및 예방을 위한 7-치환된 설폰이미도일푸린온 화합물
PL3512556T3 (pl) *	2016-09-13	2021-12-27	F. Hoffmann-La Roche Ag	Leczenie skojarzone agonistą TLR7 i inhibitorem składania kapsydu HBV
EP3752505B1 (en)	2018-02-12	2023-01-11	F. Hoffmann-La Roche AG	Novel sulfone compounds and derivatives for the treatment and prophylaxis of virus infection
MX2020008746A (es) *	2018-02-28	2020-09-28	Hoffmann La Roche	Compuestos de sulfonimidoilpurinona 7-sustituidos y sus derivados para el tratamiento y prevencion del cancer de higado.
CN111072667A (zh) *	2018-10-22	2020-04-28	罗欣药业(上海)有限公司	五元或六元杂环并嘧啶类化合物及其用途
AU2020223031B2 (en) *	2019-02-12	2024-08-29	Ambrx, Inc.	Compositions containing, methods and uses of antibody-TLR agonist conjugates
EP4031544B1 (en)	2019-09-20	2024-02-28	Syngenta Crop Protection AG	Pesticidally active heterocyclic derivatives with sulfur and sulfoximine containing substituents
WO2021154662A1 (en) *	2020-01-27	2021-08-05	Bristol-Myers Squibb Company	1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
KR20220132592A (ko) *	2020-01-27	2022-09-30	브리스톨-마이어스 스큅 컴퍼니	톨-유사 수용체 7 (TLR7) 효능제로서의 1H-피라졸로[4,3-d]피리미딘 화합물
CN119604517A (zh)	2022-07-14	2025-03-11	豪夫迈·罗氏有限公司	用于治疗癌症的磷酰基嘌呤酮化合物
CN118724963A (zh) *	2023-03-30	2024-10-01	浙江养生堂天然药物研究所有限公司	含磷或含硫的大环化合物及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4189048B2 (ja)	1997-12-26	2008-12-03	大日本住友製薬株式会社	複素環化合物
EP1888587A1 (en)	2005-05-04	2008-02-20	Pfizer Limited	2-amido-6-amino-8-oxopurine derivatives as toll-like receptor modulators for the treatment of cancer and viral infections, such as hepatitis c
CN101239980B (zh)	2008-02-18	2011-06-22	靳广毅	免疫受体调节剂偶联体前体和偶联体及其应用
WO2010077613A1 (en)	2008-12-09	2010-07-08	Gilead Sciences, Inc.	Modulators of toll-like receptors
WO2011079016A1 (en)	2009-12-22	2011-06-30	Gilead Sciences, Inc.	Methods of treating hbv and hcv infection
TWI555737B (zh) *	2011-05-24	2016-11-01	拜耳知識產權公司	含有硫醯亞胺基團之４－芳基－ｎ－苯基－１，３，５－三氮雜苯－２－胺
EP2776439B1 (en)	2011-11-09	2018-07-04	Janssen Sciences Ireland UC	Purine derivatives for the treatment of viral infections
MX366481B (es)	2013-03-29	2019-07-09	Janssen Sciences Ireland Uc	Deaza-purinonas macrociclicas para el tratamiento de infecciones virales.
LT3190113T (lt)	2014-08-15	2021-08-25	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Pirolopirimidino junginiai, naudotini kaip tlr7 agonistai
MX376761B (es) *	2015-05-08	2025-03-07	Hoffmann La Roche	Nuevos compuestos y derivados de sulfonimidoilpurinona para el tratamiento y profilaxis de infecciones víricas.
KR102459155B1 (ko) *	2016-08-29	2022-10-28	에프. 호프만-라 로슈 아게	바이러스 감염의 치료 및 예방을 위한 7-치환된 설폰이미도일푸린온 화합물

2016
- 2016-05-04 MX MX2017014033A patent/MX376761B/es active IP Right Grant
- 2016-05-04 SG SG10202108841YA patent/SG10202108841YA/en unknown
- 2016-05-04 MX MX2020010949A patent/MX393198B/es unknown
- 2016-05-04 LT LT16720421T patent/LT3294740T/lt unknown
- 2016-05-04 PL PL16720421T patent/PL3294740T3/pl unknown
- 2016-05-04 KR KR1020177035298A patent/KR102690131B1/ko active Active
- 2016-05-04 RS RSP20191351 patent/RS59435B1/sr unknown
- 2016-05-04 PT PT167204213T patent/PT3294740T/pt unknown
- 2016-05-04 JP JP2017558397A patent/JP6738352B2/ja active Active
- 2016-05-04 PE PE2017002102A patent/PE20171620A1/es unknown
- 2016-05-04 HR HRP20191942TT patent/HRP20191942T1/hr unknown
- 2016-05-04 EP EP16720421.3A patent/EP3294740B1/en active Active
- 2016-05-04 HU HUE16720421A patent/HUE045906T2/hu unknown
- 2016-05-04 SI SI201630473T patent/SI3294740T1/sl unknown
- 2016-05-04 CN CN201680026493.3A patent/CN107580596B/zh active Active
- 2016-05-04 RU RU2017142577A patent/RU2745269C2/ru active
- 2016-05-04 NZ NZ735648A patent/NZ735648A/en not_active IP Right Cessation
- 2016-05-04 CA CA2982704A patent/CA2982704C/en active Active
- 2016-05-04 MY MYPI2017704175A patent/MY182353A/en unknown
- 2016-05-04 BR BR112017023959-0A patent/BR112017023959B1/pt not_active IP Right Cessation
- 2016-05-04 NZ NZ775222A patent/NZ775222A/en unknown
- 2016-05-04 DK DK16720421T patent/DK3294740T3/da active
- 2016-05-04 ES ES16720421T patent/ES2753777T3/es active Active
- 2016-05-04 UA UAA201712023A patent/UA120450C2/uk unknown
- 2016-05-04 AU AU2016260683A patent/AU2016260683B2/en not_active Ceased
- 2016-05-04 CR CR20170496A patent/CR20170496A/es unknown
- 2016-05-04 WO PCT/EP2016/059961 patent/WO2016180695A1/en not_active Ceased
- 2016-05-05 AR ARP160101278A patent/AR104528A1/es unknown
- 2016-05-06 TW TW109131169A patent/TWI768467B/zh active
- 2016-05-06 US US15/148,309 patent/US9708325B2/en active Active
- 2016-05-06 TW TW105114192A patent/TWI706954B/zh active
2017
- 2017-06-13 US US15/621,080 patent/US10399983B2/en active Active
- 2017-09-29 CO CONC2017/0009994A patent/CO2017009994A2/es unknown
- 2017-10-09 IL IL254947A patent/IL254947B/en active IP Right Grant
- 2017-10-30 CL CL2017002745A patent/CL2017002745A1/es unknown
- 2017-11-03 PH PH12017502009A patent/PH12017502009A1/en unknown
2019
- 2019-08-02 US US16/530,229 patent/US11242345B2/en active Active
2020
- 2020-10-14 AU AU2020256348A patent/AU2020256348B2/en not_active Ceased
2021
- 2021-02-09 IL IL280769A patent/IL280769B2/en unknown
2022
- 2022-06-29 AU AU2022204666A patent/AU2022204666A1/en not_active Abandoned

Also Published As

Publication number	Publication date
RU2745269C2 (ru)	2021-03-22
TW202108584A (zh)	2021-03-01
US20160326177A1 (en)	2016-11-10
EP3294740A1 (en)	2018-03-21
US20200109144A1 (en)	2020-04-09
TWI706954B (zh)	2020-10-11
IL280769B1 (en)	2023-03-01
NZ775222A (en)	2024-09-27
SI3294740T1 (sl)	2019-12-31
US10399983B2 (en)	2019-09-03
CN107580596A (zh)	2018-01-12
NZ735648A (en)	2023-06-30
HK1247925A1 (zh)	2018-10-05
RS59435B1 (sr)	2019-11-29
IL254947B (en)	2021-02-28
BR112017023959A2 (pt)	2018-07-17
PT3294740T (pt)	2019-10-29
IL254947A0 (en)	2017-12-31
PE20171620A1 (es)	2017-11-02
HRP20191942T1 (hr)	2020-01-10
CL2017002745A1 (es)	2018-05-18
AU2016260683B2 (en)	2020-10-29
SG10202108841YA (en)	2021-09-29
CR20170496A (es)	2017-12-05
AU2020256348B2 (en)	2022-06-16
KR20180003612A (ko)	2018-01-09
EP3294740B1 (en)	2019-09-04
MX393198B (es)	2025-03-19
ES2753777T3 (es)	2020-04-14
AU2022204666A1 (en)	2022-07-21
AU2016260683A1 (en)	2017-10-12
MX2017014033A (es)	2018-03-01
KR102690131B1 (ko)	2024-07-31
MY182353A (en)	2021-01-20
AR104528A1 (es)	2017-07-26
CN107580596B (zh)	2020-07-14
JP6738352B2 (ja)	2020-08-12
UA120450C2 (uk)	2019-12-10
JP2018515509A (ja)	2018-06-14
WO2016180695A1 (en)	2016-11-17
CA2982704C (en)	2023-10-24
US9708325B2 (en)	2017-07-18
IL280769B2 (en)	2023-07-01
TWI768467B (zh)	2022-06-21
TW201716410A (zh)	2017-05-16
MX2020010949A (es)	2022-06-16
AU2020256348A1 (en)	2020-11-12
DK3294740T3 (da)	2019-11-04
PH12017502009A1 (en)	2018-03-26
IL280769A (en)	2021-04-29
US20170275286A1 (en)	2017-09-28
LT3294740T (lt)	2019-11-25
RU2017142577A3 (pl)	2019-10-31
MX376761B (es)	2025-03-07
CO2017009994A2 (es)	2018-02-20
US11242345B2 (en)	2022-02-08
HUE045906T2 (hu)	2020-01-28
CA2982704A1 (en)	2016-11-17
BR112017023959B1 (pt)	2023-05-02
RU2017142577A (ru)	2019-06-10

Publication	Publication Date	Title
IL280769A (en)	2021-04-29	New sulfonimidylpurinone compounds and their history for the treatment and prevention of virus infection
IL284255A (en)	2021-07-29	7-substituted sulfonimidylpurinone compounds for the treatment and prevention of viral infection
IL245436A0 (en)	2016-06-30	New dihydroquinolizinones for the treatment and prevention of hepatitis b virus infection
IL246449A0 (en)	2016-08-31	6-compressed new heteroaryldihydropyrimidines for the treatment and prevention of hepatitis b virus infection
IL263972A (en)	2019-01-31	Dihydropyranopyrimidines for the treatment of viral infections
SG11201509463YA (en)	2015-12-30	6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
ZA201705634B (en)	2018-12-19	Quinoline derivatives for use in the treatment or prevention of viral infection
EP3280422A4 (en)	2018-12-05	Compositions and methods for the treatment of hbv infection
SG11201702766YA (en)	2017-05-30	Spiro-indolines for the treatment and prophylaxis of respiratory syncytial virus infection (rsv)
PT3137078T (pt)	2019-06-11	Tratamento da infeção por vírus da hepatite delta
ZA201900770B (en)	2019-12-18	7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection
LT3504210T (lt)	2021-05-10	Nauji 7 padėtyje pakeisti sulfonimidoilpurinono junginiai, skirti viruso sukeliamos infekcijos gydymui ir profilaktikai
ZA201604784B (en)	2019-12-18	Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection