PL3296319T3 - Sposoby leczenia nowotworu jelita grubego - Google Patents

Sposoby leczenia nowotworu jelita grubego

Info

Publication number
PL3296319T3
PL3296319T3 PL17197865T PL17197865T PL3296319T3 PL 3296319 T3 PL3296319 T3 PL 3296319T3 PL 17197865 T PL17197865 T PL 17197865T PL 17197865 T PL17197865 T PL 17197865T PL 3296319 T3 PL3296319 T3 PL 3296319T3
Authority
PL
Poland
Prior art keywords
colon
methods
treating cancer
cancer
treating
Prior art date
Application number
PL17197865T
Other languages
English (en)
Inventor
Julie Pannequin
Leila Houhou
Berenice Framery
Nejla Erkilic
Dominique Joubert
Frederic Hollande
Original Assignee
Centre National De La Recherche Scientifique (Cnrs)
Institut National De La Sante Et De La Recherche Medicale (Inserm)
Progastrine Et Cancers S.À R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National De La Recherche Scientifique (Cnrs), Institut National De La Sante Et De La Recherche Medicale (Inserm), Progastrine Et Cancers S.À R.L. filed Critical Centre National De La Recherche Scientifique (Cnrs)
Publication of PL3296319T3 publication Critical patent/PL3296319T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046Stomach, Intestines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/595Gastrins; Cholecystokinins [CCK]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PL17197865T 2010-01-08 2011-01-07 Sposoby leczenia nowotworu jelita grubego PL3296319T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29361210P 2010-01-08 2010-01-08
US36785510P 2010-07-26 2010-07-26
EP11704178.0A EP2542585B8 (en) 2010-01-08 2011-01-07 Methods for treating colorectal cancer
EP17197865.3A EP3296319B1 (en) 2010-01-08 2011-01-07 Methods for treating colorectal cancer
PCT/EP2011/000046 WO2011083088A2 (en) 2010-01-08 2011-01-07 Methods for treating colorectal cancer

Publications (1)

Publication Number Publication Date
PL3296319T3 true PL3296319T3 (pl) 2021-09-27

Family

ID=43795093

Family Applications (2)

Application Number Title Priority Date Filing Date
PL11704178T PL2542585T3 (pl) 2010-01-08 2011-01-07 Sposoby leczenia nowotworu jelita grubego
PL17197865T PL3296319T3 (pl) 2010-01-08 2011-01-07 Sposoby leczenia nowotworu jelita grubego

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL11704178T PL2542585T3 (pl) 2010-01-08 2011-01-07 Sposoby leczenia nowotworu jelita grubego

Country Status (14)

Country Link
US (1) US9217032B2 (pl)
EP (2) EP2542585B8 (pl)
JP (1) JP5930972B2 (pl)
KR (1) KR101493261B1 (pl)
CN (1) CN102947337B (pl)
AU (1) AU2011204651B2 (pl)
BR (1) BR112012016823A2 (pl)
CA (1) CA2786417C (pl)
EA (1) EA026944B1 (pl)
ES (2) ES2657458T3 (pl)
NZ (1) NZ601584A (pl)
PL (2) PL2542585T3 (pl)
SG (1) SG182335A1 (pl)
WO (1) WO2011083088A2 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7854932B2 (en) 2006-12-19 2010-12-21 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
US8136651B2 (en) * 2007-12-14 2012-03-20 The Procter & Gamble Company Method and apparatus for orienting articles
SG181938A1 (en) 2009-12-25 2012-07-30 Pharmalogicals Res Pte Ltd Method for searching and screening for target of anti-cancer agent using non-human animal model having nog established cancer cell line transplanted therein
KR101570404B1 (ko) * 2010-03-24 2015-11-20 르 라보레또레 쎄르비에르 결장직장암 및 위창자암의 예방
EA028515B1 (ru) * 2010-07-26 2017-11-30 Ле Лаборатуар Сервье Способы и композиции для терапии рака печени
CN103328626B (zh) 2010-10-06 2017-02-08 中外制药株式会社 癌干细胞群及其制备方法
US9410955B2 (en) * 2011-06-01 2016-08-09 Inserm (Institut National De La Sante Et De La Recherche Medicale) Method for predicting the risk of developing a colonic neoplasia
WO2013035824A1 (ja) * 2011-09-07 2013-03-14 ファーマロジカルズ・リサーチ プライベート リミテッド 癌幹細胞の分離
EP2772268B8 (en) 2011-10-28 2020-01-08 Chugai Seiyaku Kabushiki Kaisha Cancer stem cell-specific molecule
EP2948775B1 (en) * 2013-01-23 2018-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for detecting neoplasia
WO2016066671A1 (en) * 2014-10-29 2016-05-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for treating resistant cancers using progastrin inhibitors
CN113968912B (zh) 2014-12-05 2025-05-16 纪念斯隆-凯特琳癌症中心 靶向g-蛋白偶联受体的嵌合抗原受体及其用途
KR102602417B1 (ko) * 2014-12-05 2023-11-16 메모리얼 슬로안 케터링 캔서 센터 G-단백질 커플화 수용체를 표적화하는 항체 및 이의 사용 방법
CA3193501A1 (en) 2015-12-31 2017-07-06 Progastrine Et Cancers S.A R.L. Compositions and methods for detecting and treating gastric cancer
WO2017114976A1 (en) 2015-12-31 2017-07-06 Progastrine Et Cancers S.À R.L. Compositions and methods for detecting and treating esophageal cancer
EP3954999B9 (en) 2015-12-31 2025-03-12 ECS-Progastrin SA Compositions and methods for detecting and treating ovarian cancer
TN2018000197A1 (en) * 2015-12-31 2019-10-04 Syncerus S A R L Compositions and methods for assessing the risk of cancer occurrence
US11561225B2 (en) 2017-03-30 2023-01-24 Progastrine Et Cancers S.À R.L. Compositions and methods for treating lung cancer
CA3058267C (en) * 2017-03-30 2023-07-25 Progastrine Et Cancers S.A R.L. Compositions and methods for detecting and treating prostate cancer using progastrin binding molecule
ES2920283T3 (es) 2017-12-05 2022-08-02 Progastrine Et Cancers S A R L Terapia de combinación entre un anticuerpo antiprogastrina y la inmunoterapia para tratar el cáncer
WO2019111998A1 (ja) * 2017-12-08 2019-06-13 京ダイアグノスティクス株式会社 癌スフェロイドの製造方法および大腸癌患者の選択方法
JP7338128B2 (ja) 2017-12-08 2023-09-05 イー、シー、エス、ビオトラッカー、エス、エー、アール、エル 癌診断における放射性標識プロガストリン
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ecs前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
EP3759492A1 (en) 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy
CN115335399A (zh) 2019-12-06 2022-11-11 朱诺治疗学股份有限公司 针对gprc5d靶结合结构域的抗独特型抗体以及相关组合物和方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
AUPO982097A0 (en) * 1997-10-15 1997-11-06 University Of Melbourne, The Methods and compositions for use therein
US20010039016A1 (en) * 2000-03-27 2001-11-08 Waldman Scott A. Use of expression profiling for identifying molecular markers useful for diagnosis of metastatic cancer
US20050074793A1 (en) 2003-04-04 2005-04-07 Wilson Keith E. Metastatic colorectal cancer signatures
EP1794586B1 (en) 2004-09-22 2013-01-30 Cancer Advances, Inc., Monoclonal antibodies to progastrin
CA2652768A1 (en) * 2006-05-22 2007-11-29 Inserm (Institut National De La Sante Et De La Recherche Medicale) Inhibitors of progastrin-induced repression of icat for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells andcells in which the beta-catenin/tcf-4-mediated transcriptional pathway is constitutively active
US7854932B2 (en) 2006-12-19 2010-12-21 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
EP2249644A4 (en) 2008-02-08 2012-05-30 Poniard Pharmaceuticals Inc PICOPLATIN AND AMRUBICIN FOR THE TREATMENT OF LUNG CANCER
US20090275546A1 (en) * 2008-04-10 2009-11-05 Istituto Superiore Di Sanita Diagnostic tests and personalized treatment regimes for cancer stem cells
US20110318380A1 (en) 2008-10-01 2011-12-29 Dako Denmark A/S MHC Multimers in Cancer Vaccines and Immune Monitoring

Also Published As

Publication number Publication date
EA026944B1 (ru) 2017-06-30
KR101493261B1 (ko) 2015-02-16
HK1252832A1 (en) 2019-06-06
BR112012016823A2 (pt) 2017-09-26
EP2542585B8 (en) 2017-12-13
WO2011083088A3 (en) 2011-10-20
EP2542585B1 (en) 2017-10-25
PL2542585T3 (pl) 2018-04-30
KR20130028049A (ko) 2013-03-18
CA2786417A1 (en) 2011-07-14
AU2011204651A1 (en) 2012-07-26
ES2657458T3 (es) 2018-03-05
EA201201000A1 (ru) 2013-02-28
EP3296319A1 (en) 2018-03-21
US20110177063A1 (en) 2011-07-21
NZ601584A (en) 2014-11-28
US9217032B2 (en) 2015-12-22
CN102947337A (zh) 2013-02-27
SG182335A1 (en) 2012-08-30
EP2542585A2 (en) 2013-01-09
CA2786417C (en) 2016-03-29
WO2011083088A2 (en) 2011-07-14
AU2011204651B2 (en) 2014-03-20
EP3296319B1 (en) 2021-03-24
CN102947337B (zh) 2016-06-01
ES2875475T3 (es) 2021-11-10
JP2013516437A (ja) 2013-05-13
JP5930972B2 (ja) 2016-06-08

Similar Documents

Publication Publication Date Title
IL289300A (en) Combination therapy for treating cancer
IL276362A (en) Cancer treatment methods
IL262956B (en) Methods for increasing efficacy of folr1 cancer therapy
LT2707030T (lt) Vėžio gydymas
PL2552438T3 (pl) Sposoby leczenia raka wątrobowokomórkowego
PL2739153T3 (pl) Leczenie raka sutka
HUE047198T2 (hu) Fitokannabinoidok emlõrák kezelésére
IL224370B (en) Combination treatment for prostate carcinoma
HUE046667T2 (hu) Rák kombinatív kezelése
BR112014007603A2 (pt) métodos de tratamento do câncer
KR101839161B9 (ko) 난소암의 치료를 위한 항혈관신생 요법
DK2717941T3 (da) Behandling af cancer
PT2897620T (pt) Método de tratamento de cancro
BR112012005594A2 (pt) tratamento de câncer
BR112013011659A2 (pt) métodos de tratamento do câncer
LT2914254T (lt) Kombinacinės terapijos chemoresistencinių vėžių gydymui
HUE045445T2 (hu) Kombinált terápia petefészekrák kezelésére
PL2742356T3 (pl) Środki prognostyczne w leczeniu nowotworów
EP2640390A4 (en) METHODS OF TREATING CANCER
DK2802351T3 (da) Midler til behandling af triple-negativ brystkræft
SI2892925T1 (sl) Kombinacijsko zdravljenje raka
PL2467140T3 (pl) Lapatynib do leczenia raka
EP2849786A4 (en) Methods for treatment of gastric cancer
EP2585115A4 (en) Cancer therapy
PL2855475T3 (pl) Alfa-karboliny do leczenia nowotworu