PL3298162T3 - Wykrywanie docelowego kwasu nukleinowego i wariantów - Google Patents

Wykrywanie docelowego kwasu nukleinowego i wariantów

Info

Publication number
PL3298162T3
PL3298162T3 PL16723135T PL16723135T PL3298162T3 PL 3298162 T3 PL3298162 T3 PL 3298162T3 PL 16723135 T PL16723135 T PL 16723135T PL 16723135 T PL16723135 T PL 16723135T PL 3298162 T3 PL3298162 T3 PL 3298162T3
Authority
PL
Poland
Prior art keywords
variants
detection
nucleic acid
target nucleic
target
Prior art date
Application number
PL16723135T
Other languages
English (en)
Inventor
Lao Hayamizu SAAL
Anthony Miles GEORGE
Original Assignee
Saga Diagnostics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saga Diagnostics Ab filed Critical Saga Diagnostics Ab
Publication of PL3298162T3 publication Critical patent/PL3298162T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/107—Temperature of melting, i.e. Tm
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/107—Probe or oligonucleotide ligation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL16723135T 2015-05-18 2016-05-18 Wykrywanie docelowego kwasu nukleinowego i wariantów PL3298162T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1550629 2015-05-18
EP16723135.6A EP3298162B1 (en) 2015-05-18 2016-05-18 Detection of target nucleic acid and variants
PCT/EP2016/061121 WO2016184902A1 (en) 2015-05-18 2016-05-18 Detection of target nucleic acid and variants

Publications (1)

Publication Number Publication Date
PL3298162T3 true PL3298162T3 (pl) 2020-07-27

Family

ID=56008652

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16723135T PL3298162T3 (pl) 2015-05-18 2016-05-18 Wykrywanie docelowego kwasu nukleinowego i wariantów

Country Status (23)

Country Link
US (2) US11066707B2 (pl)
EP (1) EP3298162B1 (pl)
JP (1) JP6956012B2 (pl)
KR (1) KR102377229B1 (pl)
CN (1) CN107636167B (pl)
AU (1) AU2016263457B2 (pl)
CA (1) CA2984960C (pl)
CY (1) CY1122788T1 (pl)
DK (1) DK3298162T3 (pl)
EA (1) EA038921B9 (pl)
ES (1) ES2775551T3 (pl)
HR (1) HRP20200321T1 (pl)
HU (1) HUE048349T2 (pl)
IL (1) IL255714B (pl)
LT (1) LT3298162T (pl)
MX (1) MX375564B (pl)
PL (1) PL3298162T3 (pl)
PT (1) PT3298162T (pl)
RS (1) RS60032B1 (pl)
SI (1) SI3298162T1 (pl)
SM (1) SMT202000260T1 (pl)
WO (1) WO2016184902A1 (pl)
ZA (1) ZA201707740B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS60032B1 (sr) * 2015-05-18 2020-04-30 Saga Diagnostics Ab Detekcija ciljne nukleinske kiseline i varijanti
KR20200115552A (ko) * 2018-01-22 2020-10-07 루미넥스 코포레이션 별개의 용융 분석을 위한 방법 및 조성물
WO2021125854A1 (ko) * 2019-12-20 2021-06-24 고려대학교 산학협력단 극소량의 희귀 단일 염기 변이체 검출용 프라이머 및 이를 이용하여 극소량의 희귀 단일 염기 변이체를 특이적이고 민감하게 검출하는 방법
WO2022067743A1 (zh) * 2020-09-30 2022-04-07 李峰 一种用于dna单核苷酸变异检测的方法、探针及试剂盒及其应用
KR102616916B1 (ko) * 2021-05-11 2023-12-21 주식회사 애이마 발암성 돌연변이 유전자 검출용 가이드 rna 내지 이의 용도
GB202203187D0 (en) 2022-03-08 2022-04-20 Rarity Bioscience Ab Method of detection of a target nucleic acid sequence
US20230392212A1 (en) 2022-06-03 2023-12-07 Saga Diagnostics Ab Detection of target nucleic acids
US20230392199A1 (en) * 2022-06-03 2023-12-07 Saga Diagnostics Ab Detection of target nucleic acids with preamplification
EP4581159A1 (en) 2022-08-31 2025-07-09 Saga Diagnostics AB Multi-vector detection of variant sequences
EP4581157A2 (en) 2022-08-31 2025-07-09 Saga Diagnostics AB Detection of variant esr1 sequences
US20240352512A1 (en) 2023-04-24 2024-10-24 Saga Diagnostics Ab Detection of variants
CN117816262A (zh) * 2024-01-05 2024-04-05 湖南工程学院 一种检测癌症突变基因的一步式微流控微珠阵列芯片、试剂盒及其应用
BG67854B1 (bg) * 2024-02-02 2026-04-15 Медицински университет – Пловдив КОМПЛЕКТ ЗА МОЛЕКУЛЯРНО-ГЕНЕТИЧНА ДЕТЕКЦИЯ И КОЛИЧЕСТВEНО ОПРЕДЕЛЯНЕ НА МУТАЦИЯ P.H1047R В PIK3CA ГЕНА В ТУМОРНА ТЪКАН И/ИЛИ ПЕРИФЕРНА КРЪВ ЧРЕЗ ДИГИТАЛЕН КАПКОВ (ddPCR) МЕТОД

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US20040022764A1 (en) * 2002-07-31 2004-02-05 Hanan Polansky Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease
JP4353504B2 (ja) * 2003-05-19 2009-10-28 キヤノン株式会社 核酸の増幅方法および標識化方法、これを用いた核酸検出方法
WO2006094360A1 (en) 2005-03-11 2006-09-14 Molecular Plant Breeding Nominees Ltd Method of amplifying nucleic acid
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RS60032B1 (sr) * 2015-05-18 2020-04-30 Saga Diagnostics Ab Detekcija ciljne nukleinske kiseline i varijanti

Also Published As

Publication number Publication date
IL255714A (en) 2018-01-31
AU2016263457B2 (en) 2020-08-27
MX2017014771A (es) 2018-08-15
CN107636167A (zh) 2018-01-26
EP3298162B1 (en) 2019-11-27
ZA201707740B (en) 2021-04-28
HRP20200321T1 (hr) 2020-06-12
KR20180019585A (ko) 2018-02-26
JP2018523970A (ja) 2018-08-30
KR102377229B1 (ko) 2022-03-22
SI3298162T1 (sl) 2020-06-30
CY1122788T1 (el) 2021-05-05
MX375564B (es) 2025-03-06
WO2016184902A1 (en) 2016-11-24
ES2775551T3 (es) 2020-07-27
AU2016263457A1 (en) 2017-12-07
HUE048349T2 (hu) 2020-07-28
LT3298162T (lt) 2020-03-10
CA2984960C (en) 2022-10-04
US20180340230A1 (en) 2018-11-29
CN107636167B (zh) 2022-09-02
EP3298162A1 (en) 2018-03-28
SMT202000260T1 (it) 2020-07-08
RS60032B1 (sr) 2020-04-30
EA201792405A1 (ru) 2018-07-31
US11066707B2 (en) 2021-07-20
PT3298162T (pt) 2020-03-26
BR112017024702A2 (pt) 2018-09-18
JP6956012B2 (ja) 2021-10-27
CA2984960A1 (en) 2016-11-24
US20220056533A1 (en) 2022-02-24
DK3298162T3 (da) 2020-03-02
EA038921B1 (ru) 2021-11-10
IL255714B (en) 2020-09-30
EA038921B9 (ru) 2021-12-06

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