PL3302473T3 - Wytwarzanie cytrynianu sufentanylu i zasady sufentanylu - Google Patents

Wytwarzanie cytrynianu sufentanylu i zasady sufentanylu

Info

Publication number
PL3302473T3
PL3302473T3 PL16800663T PL16800663T PL3302473T3 PL 3302473 T3 PL3302473 T3 PL 3302473T3 PL 16800663 T PL16800663 T PL 16800663T PL 16800663 T PL16800663 T PL 16800663T PL 3302473 T3 PL3302473 T3 PL 3302473T3
Authority
PL
Poland
Prior art keywords
sufentanil
preparation
base
citrate
sufentanil citrate
Prior art date
Application number
PL16800663T
Other languages
English (en)
Inventor
George Helmut KLEMM
Brian Orr
Joel MCCLENAGHAN
Original Assignee
SpecGx LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SpecGx LLC filed Critical SpecGx LLC
Publication of PL3302473T3 publication Critical patent/PL3302473T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL16800663T 2015-05-27 2016-05-25 Wytwarzanie cytrynianu sufentanylu i zasady sufentanylu PL3302473T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562166911P 2015-05-27 2015-05-27
PCT/US2016/034091 WO2016191472A1 (en) 2015-05-27 2016-05-25 Preparation of sufentanil citrate and sufentanil base
EP16800663.3A EP3302473B1 (en) 2015-05-27 2016-05-25 Preparation of sufentanil citrate and sufentanil base

Publications (1)

Publication Number Publication Date
PL3302473T3 true PL3302473T3 (pl) 2020-12-14

Family

ID=57393664

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16800663T PL3302473T3 (pl) 2015-05-27 2016-05-25 Wytwarzanie cytrynianu sufentanylu i zasady sufentanylu

Country Status (10)

Country Link
US (5) US10227335B2 (pl)
EP (1) EP3302473B1 (pl)
JP (4) JP2018515580A (pl)
AU (1) AU2016268344B2 (pl)
BR (1) BR112017025115B1 (pl)
CA (1) CA2986764A1 (pl)
ES (1) ES2806631T3 (pl)
MX (1) MX381426B (pl)
PL (1) PL3302473T3 (pl)
WO (1) WO2016191472A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016191472A1 (en) 2015-05-27 2016-12-01 Mallinckrodt Llc Preparation of sufentanil citrate and sufentanil base

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179569A (en) * 1975-03-14 1979-12-18 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-N-phenylamides
US3998834A (en) 1975-03-14 1976-12-21 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-n-phenylamides and -carbamates
US5039804A (en) * 1989-12-13 1991-08-13 Glaxo Inc. Preparation of substituted alkali metal piperidine-4-carboxylates
US5489689A (en) * 1993-09-30 1996-02-06 Mallinckrodt Chemical, Inc. Preparation of piperidine derivatives
US6342250B1 (en) * 1997-09-25 2002-01-29 Gel-Del Technologies, Inc. Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices
CA2393559C (en) 1999-12-06 2009-05-26 Mallinckrodt Inc. Methods for the syntheses of alfentanil, sufentanil and remifentanil
AU2002335080A1 (en) * 2001-10-17 2003-04-28 E.I. Du Pont De Nemours And Company Rotor-stator apparatus and process for the formation of particles
WO2008005423A1 (en) * 2006-07-03 2008-01-10 Cambrex Charles City, Inc. Improved method of making sufentanil
WO2008100434A1 (en) 2007-02-09 2008-08-21 Durect Corporation Transoral dosage forms comprising sufentanil and naloxone
US20100056574A1 (en) * 2008-09-04 2010-03-04 Mallinckrodt Inc. Crystalline Forms of Sufentanil
US8299258B2 (en) 2008-11-04 2012-10-30 Cambrex Charles City Method of making piperidine derivatives
US8946433B2 (en) * 2010-09-17 2015-02-03 Mallinckrodt Llc Process for the preparation of sufentanil base and related compounds
EP2455377B1 (de) 2010-11-11 2014-07-09 hameln rds gmbh Synthese von Fentanyl Analoga
CN102060753B (zh) * 2010-12-29 2013-01-09 宜昌人福药业有限责任公司 一种4-苯胺基哌啶类镇痛药的精制方法
JP6146613B2 (ja) 2013-09-04 2017-06-14 東芝ライテック株式会社 自動車用照明装置、および自動車用灯具
WO2016191472A1 (en) * 2015-05-27 2016-12-01 Mallinckrodt Llc Preparation of sufentanil citrate and sufentanil base

Also Published As

Publication number Publication date
JP2021059609A (ja) 2021-04-15
US20210061793A1 (en) 2021-03-04
EP3302473A1 (en) 2018-04-11
JP2018515580A (ja) 2018-06-14
CA2986764A1 (en) 2016-12-01
EP3302473A4 (en) 2019-04-17
US20250368630A1 (en) 2025-12-04
US20160347743A1 (en) 2016-12-01
BR112017025115B1 (pt) 2023-03-14
US20190152961A1 (en) 2019-05-23
EP3302473B1 (en) 2020-07-08
JP2023036903A (ja) 2023-03-14
AU2016268344B2 (en) 2020-03-26
ES2806631T3 (es) 2021-02-18
US12371423B2 (en) 2025-07-29
BR112017025115A2 (pt) 2018-07-31
JP2024138039A (ja) 2024-10-07
US10227335B2 (en) 2019-03-12
AU2016268344A1 (en) 2017-11-30
JP7525589B2 (ja) 2024-07-30
US10899749B2 (en) 2021-01-26
US20230074804A1 (en) 2023-03-09
MX2017015100A (es) 2018-08-09
MX381426B (es) 2025-03-12
WO2016191472A1 (en) 2016-12-01

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