PL3305768T3 - Sól sodowa inhibitora transportera kwasu moczowego i jego forma krystaliczna - Google Patents

Sól sodowa inhibitora transportera kwasu moczowego i jego forma krystaliczna

Info

Publication number
PL3305768T3
PL3305768T3 PL16799331T PL16799331T PL3305768T3 PL 3305768 T3 PL3305768 T3 PL 3305768T3 PL 16799331 T PL16799331 T PL 16799331T PL 16799331 T PL16799331 T PL 16799331T PL 3305768 T3 PL3305768 T3 PL 3305768T3
Authority
PL
Poland
Prior art keywords
sodium salt
crystalline form
uric acid
acid transporter
transporter inhibitor
Prior art date
Application number
PL16799331T
Other languages
English (en)
Inventor
Guaili Wu
Zhenjun QIU
Yunpeng Su
Xi LU
Original Assignee
Jiangsu Hengrui Medicine Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hengrui Medicine Co., Ltd. filed Critical Jiangsu Hengrui Medicine Co., Ltd.
Publication of PL3305768T3 publication Critical patent/PL3305768T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
PL16799331T 2015-05-27 2016-05-26 Sól sodowa inhibitora transportera kwasu moczowego i jego forma krystaliczna PL3305768T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510280720 2015-05-27
EP16799331.0A EP3305768B1 (en) 2015-05-27 2016-05-26 Sodium salt of uric acid transporter inhibitor and crystalline form thereof
PCT/CN2016/083423 WO2016188444A1 (zh) 2015-05-27 2016-05-26 一种尿酸转运蛋白抑制剂的钠盐及其结晶形式

Publications (1)

Publication Number Publication Date
PL3305768T3 true PL3305768T3 (pl) 2020-12-28

Family

ID=57393793

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16799331T PL3305768T3 (pl) 2015-05-27 2016-05-26 Sól sodowa inhibitora transportera kwasu moczowego i jego forma krystaliczna

Country Status (22)

Country Link
US (2) US10196361B2 (pl)
EP (1) EP3305768B1 (pl)
JP (1) JP6738350B2 (pl)
KR (1) KR20180006441A (pl)
CN (1) CN107001276B (pl)
AU (1) AU2016269359B2 (pl)
BR (1) BR112017022505A2 (pl)
CA (1) CA2984961C (pl)
CY (1) CY1123262T1 (pl)
DK (1) DK3305768T3 (pl)
ES (1) ES2811325T3 (pl)
HR (1) HRP20201178T1 (pl)
HU (1) HUE051640T2 (pl)
LT (1) LT3305768T (pl)
MX (1) MX379184B (pl)
PL (1) PL3305768T3 (pl)
PT (1) PT3305768T (pl)
RS (1) RS60749B1 (pl)
RU (1) RU2719484C2 (pl)
SI (1) SI3305768T1 (pl)
SM (1) SMT202000421T1 (pl)
WO (1) WO2016188444A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3305768T3 (pl) * 2015-05-27 2020-12-28 Jiangsu Hengrui Medicine Co., Ltd. Sól sodowa inhibitora transportera kwasu moczowego i jego forma krystaliczna
CN108201529B (zh) * 2016-12-16 2021-10-08 江苏恒瑞医药股份有限公司 一种含有尿酸转运蛋白抑制剂的药物组合物及其制备方法
CN110467571B (zh) * 2018-05-11 2021-02-26 江苏恒瑞医药股份有限公司 一种制备环烷基甲酸类衍生物或其可药用盐的方法
WO2025072489A2 (en) 2023-09-27 2025-04-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SA04250253B1 (ar) * 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
MX362747B (es) * 2013-05-13 2019-02-05 Shanghai hengrui pharmaceutical co ltd Derivado de ácido cicloalquilo, método de preparación del mismo, y aplicación farmacéutica del mismo.
PL3305768T3 (pl) * 2015-05-27 2020-12-28 Jiangsu Hengrui Medicine Co., Ltd. Sól sodowa inhibitora transportera kwasu moczowego i jego forma krystaliczna

Also Published As

Publication number Publication date
ES2811325T3 (es) 2021-03-11
EP3305768A4 (en) 2019-02-13
SMT202000421T1 (it) 2020-09-10
KR20180006441A (ko) 2018-01-17
PT3305768T (pt) 2020-08-03
CA2984961A1 (en) 2016-12-01
EP3305768A1 (en) 2018-04-11
US20180134663A1 (en) 2018-05-17
US20190040015A1 (en) 2019-02-07
CN107001276B (zh) 2020-03-13
CY1123262T1 (el) 2021-12-31
HUE051640T2 (hu) 2021-03-01
LT3305768T (lt) 2020-08-25
CN107001276A (zh) 2017-08-01
MX2017014319A (es) 2018-03-07
BR112017022505A2 (pt) 2018-07-17
RU2017142996A (ru) 2019-06-27
JP6738350B2 (ja) 2020-08-12
JP2018515454A (ja) 2018-06-14
DK3305768T3 (da) 2020-08-10
HRP20201178T1 (hr) 2020-11-13
SI3305768T1 (sl) 2020-10-30
RS60749B1 (sr) 2020-10-30
US10196361B2 (en) 2019-02-05
RU2719484C2 (ru) 2020-04-17
RU2017142996A3 (pl) 2019-11-20
AU2016269359B2 (en) 2020-02-06
EP3305768B1 (en) 2020-07-01
MX379184B (es) 2025-03-10
CA2984961C (en) 2023-08-01
US10358424B2 (en) 2019-07-23
AU2016269359A1 (en) 2017-11-23
WO2016188444A1 (zh) 2016-12-01

Similar Documents

Publication Publication Date Title
TWI560185B (en) Acid addition salt of trk inhibitor compound
DK2970123T4 (da) Krystallinsk dihydrochloridhydratsalt af omecamtiv mecarbil og fremgangsmåde til fremstilling heraf
HUE050414T2 (hu) Eljárás hialuronsav nátriumsója elõállítására és tisztítására
SG11201706917WA (en) Salts of pi3k inhibitor and processes for their preparation
PT3481819T (pt) Compostos e a sua utilização para reduzir os níveis de ácido úrico
IL259998A (en) Polymorphic crystalline forms of obeticholic acid
EP3071554A4 (en) Crystalline forms of lesinurad and its sodium salt
PL3148661T3 (pl) Sposób oczyszczania kwasu benzoesowego
EP3247761A4 (en) Use of hydroxyacid to reduce the localized corrosion potential of low dose hydrate inhibitors
IL256127B (en) Use of benzimidazole history for nocturnal acid reflux
HUE043194T2 (hu) PLK-4 inhibitor sója és kristályformái
IL248567A0 (en) Using compounds known as d-amino acid oxidase inhibitors
PL3632904T3 (pl) Inhibitory urat1 do pobudzania wydalania kwasu moczowego
IL269073A (en) Crystalline forms of obeticholic acid
SI3305768T1 (sl) Natrijeva sol inhibitorja transporterja sečne kisline in kristalinična oblika le-te
IL253726A0 (en) Preparations for the treatment of inflammatory diseases related to uric acid
EP3199529A4 (en) Salt of dicarboxylic acid compound
HUE052088T2 (hu) Neridronsav vagy sójának alkalmazása osteoarthrosis kezelésére
ZA201901155B (en) Salt and crystal of diaza-benzofluorane compound
GB201617044D0 (en) Inhibitor of citrate transporter
FIC20170021I1 (fi) deoksikoolihapon natriumsuola
GB201517998D0 (en) Inhibitor of citrate transporter
GB201515692D0 (en) Inhibitor of citrate transporter