PL3307289T3 - Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt) - Google Patents

Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt)

Info

Publication number
PL3307289T3
PL3307289T3 PL16732111T PL16732111T PL3307289T3 PL 3307289 T3 PL3307289 T3 PL 3307289T3 PL 16732111 T PL16732111 T PL 16732111T PL 16732111 T PL16732111 T PL 16732111T PL 3307289 T3 PL3307289 T3 PL 3307289T3
Authority
PL
Poland
Prior art keywords
mrt
compositions
manufacture
methods
restoration therapy
Prior art date
Application number
PL16732111T
Other languages
English (en)
Inventor
Lee A. Jones
Courtney R. JONES
Beth Anne-Szkudlarek Brown
Joshua ERICKSON
Original Assignee
Rebiotix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rebiotix, Inc. filed Critical Rebiotix, Inc.
Publication of PL3307289T3 publication Critical patent/PL3307289T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL16732111T 2015-06-09 2016-06-09 Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt) PL3307289T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562173182P 2015-06-09 2015-06-09
US201562247825P 2015-10-29 2015-10-29
PCT/US2016/036714 WO2016201114A1 (en) 2015-06-09 2016-06-09 Microbiota restoration therapy (mrt) compositions and methods of manufacture
EP16732111.6A EP3307289B1 (en) 2015-06-09 2016-06-09 Methods of manufacture of microbiota restoration therapy (mrt) compositions

Publications (1)

Publication Number Publication Date
PL3307289T3 true PL3307289T3 (pl) 2022-01-17

Family

ID=56203991

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16732111T PL3307289T3 (pl) 2015-06-09 2016-06-09 Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt)

Country Status (12)

Country Link
US (2) US10226431B2 (pl)
EP (2) EP3307289B1 (pl)
JP (2) JP6616431B2 (pl)
KR (3) KR102066242B1 (pl)
CN (1) CN107921072A (pl)
AU (5) AU2016274757B2 (pl)
BR (1) BR112017026586B1 (pl)
CA (1) CA2986915C (pl)
ES (1) ES2889902T3 (pl)
IL (2) IL281424B2 (pl)
PL (1) PL3307289T3 (pl)
WO (1) WO2016201114A1 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3564357T3 (da) 2010-02-01 2022-06-20 Rebiotix Inc Bakterieterapi mod clostridium difficile colitis
KR102099503B1 (ko) 2013-06-05 2020-04-09 리바이오틱스, 인코퍼레이티드 미생물상 복원 요법(mrt) 조성물
US12050161B2 (en) 2015-04-24 2024-07-30 Maat Pharma Microorganism sampling method, microorganism sampling device and sampling kit comprising such a sampling device
FR3035328B1 (fr) 2015-04-24 2019-08-23 Maat Pharma Procede de preparation d'un echantillon de microbiote fecal
FR3035317B1 (fr) 2015-04-24 2019-06-14 Maat Pharma Dispositif de prelevement de micro-organismes, kit de prelevement comprenant un tel dispositif et procede de prelevement mettant en œuvre un tel dispositif
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10443935B2 (en) * 2015-08-03 2019-10-15 Gen-Probe Incorporated Apparatus for maintaining a controlled environment
FR3045383B1 (fr) 2015-12-18 2019-06-14 Maat Pharma Procede de lyophilisation d'un echantillon de microbiote fecal
US10092601B2 (en) * 2016-10-11 2018-10-09 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
EP3606325B1 (en) 2017-04-03 2024-09-04 Gusto Global, LLC Rational design of microbial-based biotherapeutics
EP3388069B1 (en) 2017-04-12 2019-05-01 ETH Zurich Consortia of living bacteria useful for treatment of microbiome dysbiosis
US20220125042A1 (en) * 2017-05-17 2022-04-28 Universidade Nova De Lisboa Cryoprotectant and/or cryopreservant composition, methods and uses thereof
CN107422021B (zh) * 2017-07-14 2019-11-19 北京朗阅科技有限公司 琼脂糖胶囊及其制备方法与应用
MX2020004204A (es) * 2017-10-13 2020-08-13 Rebiotix Inc Indice de salud del microbioma.
EP3485879A1 (en) 2017-11-17 2019-05-22 Maat Pharma Pharmaceutical oral formulation comrpsing bacteria
WO2019213595A1 (en) 2018-05-04 2019-11-07 Ferring B.V. Microbiota restoration therapy (mrt) compositions and methods of manufacture
KR20240091008A (ko) * 2018-06-14 2024-06-21 리바이오틱스, 인코퍼레이티드 미생물총 회복 요법 조성물 및 제조 방법
CN112703005A (zh) * 2018-07-17 2021-04-23 费灵有限公司 包括微生物群恢复治疗（mrt）组合物的联合疗法
CN109679877A (zh) * 2019-01-17 2019-04-26 广州承葛生物科技有限公司 一种高活性粪菌胶囊的制备方法
JP2022548785A (ja) 2019-09-24 2022-11-21 プロラクタ バイオサイエンス，インコーポレイテッド 炎症性疾患及び免疫疾患の治療のための組成物及び方法
EP4045069A1 (en) 2019-10-18 2022-08-24 Thaena Inc. Fecal-derived sterile postbiotic composition and method therefor
JP7653147B2 (ja) 2019-12-30 2025-03-28 奇▲輝▼生物科技（▲揚▼州）有限公司 腸管内容物分離回収装置、方法及び抽出物
WO2021247571A1 (en) 2020-06-01 2021-12-09 Ferring B.V. Vaginal microbiota compositions
KR20230088680A (ko) 2020-08-14 2023-06-20 프롤랙타 바이오사이언스, 인코포레이티드 박테리아 요법에 사용하기 위한 인간 모유 올리고당 조성물
WO2022051610A1 (en) 2020-09-04 2022-03-10 Ferring B.V. Microbiota restoration therapy (mrt) compositions and methods of manufacture
CN112089736B (zh) * 2020-09-22 2022-07-15 苏州普瑞森生物科技有限公司 一种全菌胶囊及其制备方法和应用
CN112826836A (zh) * 2021-01-08 2021-05-25 深圳未知君生物科技有限公司 一种粪菌口服制剂及其制备方法
CN116218677A (zh) * 2023-03-31 2023-06-06 南京法迈特科技发展有限公司 一种粪菌菌液保护剂及其应用和粪菌菌液的制备方法
WO2025210272A1 (en) 2024-04-05 2025-10-09 Ferring B.V. Composition comprising lactobacillus species for vaginal therapies

Family Cites Families (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL257275A (pl) 1959-10-26
DE3887353T2 (de) 1987-10-12 1994-05-05 Capability Services Pty Ltd Behandlungsverfahren für magen-darm-krankheiten.
US5274001A (en) 1987-12-24 1993-12-28 Borody Thomas J Orthostatic lavage solutions
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
DE68928665T2 (de) 1988-08-02 1998-11-12 Gastro Services Pty Ltd Behandlung von gastro-intestinalen krankheiten
CA1337265C (en) 1988-08-04 1995-10-10 Thomas Julius Borody Oral antibody therapy for patients with lowered immune response and composition therefor
CA2090220C (en) 1990-10-22 2003-07-08 Thomas Julius Borody Treatment of non-inflammatory and non-infectious bowel disorders
US5519014A (en) 1990-10-22 1996-05-21 Borody; Thomas J. Treatment of non-inflammatory and non-infectious bowel disorders
US5229374A (en) 1992-01-28 1993-07-20 Burton Albert F Method for treatment of lower gastrointestinal tract disorders
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
AUPM864894A0 (en) 1994-10-07 1994-11-03 Borody, Thomas Julius Treatment of bowel-dependent neurological disorders
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US5656283A (en) 1995-06-08 1997-08-12 Ortho Pharmaceutical Corporation In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product
ES2248822T3 (es) 1995-09-15 2006-03-16 Dale N. Gerding Procedimientos y composiciones para la prevencion y el tratamiento de enfermedades asociadas al clostridium difficile.
AUPN634595A0 (en) 1995-11-03 1995-11-30 Borody, Thomas Julius Improved method for colonic evacuation
US6103268A (en) 1995-11-03 2000-08-15 Borody; Thomas Julius Administering osmotic colonic evacuant containing a picosulfate
US5925354A (en) 1995-11-30 1999-07-20 Michigan State University Riboflavin mutants as vaccines against Actinobacillus pleuropneumoniae
US5711446A (en) 1996-01-16 1998-01-27 Sorenson Bioscience, Inc. Cryogenic freezing vial
US6096310A (en) 1997-04-15 2000-08-01 Bier; Milan Oral immunotherapy of bacterial overgrowth
AUPO665397A0 (en) 1997-05-07 1997-05-29 Borody, Thomas Julius Novel therapy for constipation
US6969520B2 (en) 1997-10-20 2005-11-29 Acambis Inc. Active immunization against clostridium difficile disease
EP2305303A3 (en) 1997-10-20 2013-11-13 Sanofi Pasteur Biologics Co. Immunization against Clostridium difficile disease
US6428783B1 (en) 1998-03-11 2002-08-06 Medtech Center, Inc. Bank of autochthonous strains of microorganisms and methods of its use for recovery of intestinal microbiocenosis of the men
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
US7430478B2 (en) 2000-03-01 2008-09-30 Caridian Bct, Inc. Blood processing information system with blood loss equivalency tracking
FR2808689B1 (fr) 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20040062757A1 (en) 2001-06-05 2004-04-01 Finegold Sydney M. Method of testing gastrointestinal diseases associated with species of genus clostridium
CN1444484A (zh) 2000-06-19 2003-09-24 穆科普罗泰科有限公司 用益生菌对粘膜表面的细菌或病毒感染进行治疗或免疫治疗及用于此的组合物
EP1303285A2 (en) 2000-07-17 2003-04-23 Chr. Hansen A/S Methods and formulations with probiotic microorganisms and medicaments
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
AU2002902A (en) 2000-11-14 2002-05-27 Techlab Inc Method for differentiating irritable bowel syndrome from inflammatory bowel disease (ibd) and for monitoring persons with ibd using total endogenous lactoferrinas a marker
EP2295081B1 (en) 2001-06-26 2018-10-31 Amgen Inc. Antibodies to OPGL
DK2184346T3 (en) 2001-09-06 2017-06-26 Rapid Micro Biosystems Inc Rapid detection of replicating cells
EP1300472A1 (en) 2001-10-02 2003-04-09 Stichting Top-Instituut Voedselwetenschappen A method for testing the effect of nutrients on gastrointestinal colonisation resistance of humans
GB0124580D0 (en) 2001-10-12 2001-12-05 Univ Reading New composition
EP1448987A4 (en) 2001-12-10 2005-06-08 Ardais Corp SYSTEM AND METHODS FOR OBTAINING PATIENT SAMPLES IN CORRELATION WITH DATA
US20030161871A1 (en) 2001-12-19 2003-08-28 Geoffrey Hird Solubilized riboflavin
AUPS088702A0 (en) 2002-03-04 2002-03-28 Borody, Thomas Julius Electrolyte purgative
US20040002451A1 (en) * 2002-06-20 2004-01-01 Bruce Kerwin Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing
ATE513551T1 (de) 2003-01-24 2011-07-15 Flora Technology Inc Zusammensetzungen und verfahren zur wiederherstellung der bakterienflora
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
US7935334B2 (en) 2005-07-07 2011-05-03 Imagilin Technologies, LLC Probiotics as alternative medicines against infectious diseases
US20060008511A1 (en) 2004-07-08 2006-01-12 Jhy-Jhu Lin Probiotic products for pet applications
AU2005335216A1 (en) 2004-10-05 2007-02-15 Wyeth Probe arrays for detecting multiple strains of different species
AU2005306801B2 (en) 2004-11-08 2012-05-17 The Regents Of The University Of Colorado Structure-based compound design involving riboswitches
US20060210448A1 (en) 2005-03-10 2006-09-21 Naishu Wang Fecal specimen collection, preserving and transport device and method
US7607776B1 (en) 2005-10-24 2009-10-27 James Waller Lambuth Lewis Digital eye bank for virtual clinic trials
WO2007100412A2 (en) 2005-12-21 2007-09-07 Yale University Methods and compositions related to the modulation of riboswitches
EP1978821B2 (en) 2005-12-29 2019-02-06 Hill's Pet Nutrition, Inc. Method for modifying gut flora in animals
US20080027353A1 (en) 2006-07-31 2008-01-31 Kliman Harvey J Method of making and using a library of biological information
EP2102350A4 (en) 2006-12-18 2012-08-08 Univ St Louis DARMMICROBIOMA AS A BIOMARKER AND THERAPEUTIC OBJECT FOR THE TREATMENT OF ADIPOSITAS OR ADIPOSITASCONDUCTIVE DISEASES
EP2030623A1 (en) 2007-08-17 2009-03-04 Nestec S.A. Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria
EP2211879B1 (en) * 2007-10-26 2014-05-07 Brenda E. Moore Probiotic compositions and methods for inducing and supporting weight loss
US20090148540A1 (en) 2007-12-10 2009-06-11 Mi Hope Incorporated Antibacterial composition and method of production
AR072777A1 (es) * 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
US20110237549A1 (en) 2008-03-27 2011-09-29 Memorial Sloan Kettering Cancer Center Modulators of rna riboswitches
WO2010002890A2 (en) 2008-06-30 2010-01-07 The Washington University Methods of promoting weight loss and associated arrays
US20100008850A1 (en) 2008-07-14 2010-01-14 William John Martin Method of generating hydrogen in drinking water using an enerceutical product added to magnesium in a hydrogen permeable but solute impermeable container
WO2010009241A2 (en) 2008-07-17 2010-01-21 Bioworks, Inc. Control of plant diseases and enhancing plant growth using a combination of a trichoderma virens species and a rhizosphere competent trichoderma harzianum species
US20120077781A1 (en) 2008-08-11 2012-03-29 Robert Gadwood Flavin derivatives
EP2243487A1 (en) 2009-04-23 2010-10-27 Actogenix N.V. Enteric coated formulation
GB0916335D0 (en) 2009-09-17 2009-10-28 Martin W J Medicaments
PL2480255T3 (pl) 2009-09-23 2018-07-31 Thomas Julius Borody Terapia przewlekłych zakażeń jelitowych
DE112010004110T8 (de) 2009-10-22 2012-12-06 Thomas Julius Borody Neue parasitentherapie
US8772242B2 (en) 2009-10-26 2014-07-08 Thomas Julius Borody Therapy for enteric infections
DK3564357T3 (da) 2010-02-01 2022-06-20 Rebiotix Inc Bakterieterapi mod clostridium difficile colitis
US8853269B2 (en) 2010-02-04 2014-10-07 Copperhead Chemical Company Inc. Composition and method for treating infections and promoting intestinal health
US20130005586A1 (en) 2010-03-01 2013-01-03 Stanislav Ehrlich Method of diagnostic of obesity
US20130045874A1 (en) 2010-03-01 2013-02-21 Institut National De La Recherche Agronomique Method of Diagnostic of Inflammatory Bowel Diseases
FI20105478A0 (fi) 2010-04-30 2010-04-30 Valtion Teknillinen Menetelmä tyypin 1 diabeteksen diagnosoimiseksi ja menetelmiä ja koostumuksia tyypin 1 diabeteksen puhkeamisen estämiseksi
US9707207B2 (en) 2010-05-26 2017-07-18 The United States Of America As Represented By The Department Of Veterans Affairs Method for diagnosing, preventing, and treating neurological diseases
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物
FI20105825A7 (fi) 2010-07-26 2012-01-27 Suomen Punainen Risti Veripalvelu Veriryhmästatuksen käyttö III
WO2012013861A2 (en) 2010-07-26 2012-02-02 Suomen Punainen Risti Veripalvelu Use of blood group status iii
EP3424515A3 (en) * 2010-08-04 2019-06-19 Thomas Julius Borody Stool collection devices and methods for using them
US9386793B2 (en) 2010-08-20 2016-07-12 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
EP2613802A4 (en) 2010-09-10 2014-03-26 Viropharma Inc ENVIRONMENTAL CLOSTRIDAL BACTERIOTHERAPY AND ASSOCIATED FORMULATIONS AND METHODS OF MAKING AND USING SAME
WO2012050513A1 (en) 2010-10-11 2012-04-19 Baeckhed Fredrik Method for identifying a risk of cardiovascular disease by analysing oral microbiota
CN103687604A (zh) 2011-03-01 2014-03-26 群体创新有限责任公司 用于治疗与致病生物膜相关之病症的材料和方法
US9968638B2 (en) 2011-03-09 2018-05-15 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2012122522A2 (en) 2011-03-09 2012-09-13 Washington University Cultured collection of gut microbial community
WO2014152484A1 (en) * 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Freeze dried fecal microbiota for use in fecal microbial transplantation
WO2012142605A1 (en) 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent
US20120276059A1 (en) 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for monitoring infection in patients with clostridium difficile disease
WO2012159023A2 (en) 2011-05-19 2012-11-22 Virginia Commonwealth University Gut microflora as biomarkers for the prognosis of cirrhosis and brain dysfunction
US20130022575A1 (en) 2011-07-19 2013-01-24 Microbial Rx Systems and methods of replacing intestinal flora
CA2846804A1 (en) 2011-08-26 2013-03-07 Microbiota Diagnostics, Llc Methods for diagnosing and treating cardiac defects
US20140363397A1 (en) 2011-09-14 2014-12-11 Queen's University At Kingston Method for treatment of disorders of the gastrointestinal system
CN103857402A (zh) 2011-10-11 2014-06-11 阿基姆医药公司 包括厌氧培养的人类肠道微生物群的组合物
JP6219836B2 (ja) * 2011-11-09 2017-10-25 キャプシュゲル・ベルジウム・エヌ・ヴィ 耐酸性ツーピースハードカプセル用の耐酸性バンディング溶液
US9176026B2 (en) 2011-12-15 2015-11-03 Pureflora, Inc. Device for the collection, refinement, and administration of gastrointestinal microflora
EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
US9421233B2 (en) 2012-04-27 2016-08-23 Cedars-Sinai Medical Center Fungal mycobiome as probiotics, diagnostics and therapeutics
US10130665B2 (en) 2012-05-18 2018-11-20 Genome Research Limited Method for identifying bacteria for bacteriotherapy
KR20150027154A (ko) 2012-07-02 2015-03-11 디에스엠 아이피 어셋츠 비.브이. 타이모퀴논을 함유하는 캡슐
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
SG11201503966PA (en) 2012-11-23 2015-06-29 Seres Health Inc Synergistic bacterial compositions and methods of production and use thereof
EP2922555A4 (en) * 2012-11-26 2016-06-15 Borody Thomas J COMPOSITIONS FOR THE RESTORATION OF A FÄKALBIOZÖNOSE AND METHOD FOR THE PRODUCTION AND USE THEREOF
CA2931835C (en) 2012-11-29 2021-02-23 Progel Pty Ltd Microparticles comprising a probiotic, cross-linkable reagent, a denatured protein, polyol plasticiser and trehalose
JP2016509003A (ja) 2013-02-04 2016-03-24 セレス セラピューティクス インコーポレイテッド 組成物および方法
US10973861B2 (en) 2013-02-04 2021-04-13 Seres Therapeutics, Inc. Compositions and methods
US9192361B2 (en) 2013-02-26 2015-11-24 Christopher J Stevens Fecal microbiome transplant material preparation method and apparatus
EP2971148A4 (en) 2013-03-14 2016-08-17 Seres Therapeutics Inc METHODS OF DETECTING PATHOGENS AND ENRICHING FROM MATERIALS AND COMPOSITIONS
WO2014145958A2 (en) 2013-03-15 2014-09-18 Seres Health, Inc. Network-based microbial compositions and methods
US9511100B2 (en) * 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
KR102099503B1 (ko) 2013-06-05 2020-04-09 리바이오틱스, 인코퍼레이티드 미생물상 복원 요법(mrt) 조성물
US20150037285A1 (en) 2013-07-03 2015-02-05 New York University Methods for efficient transfer of viable and bioactive microbiota
EP3035944B1 (en) 2013-08-22 2019-10-02 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Probiotics for use in the treatment of bacterial vaginosis
JP2015091647A (ja) 2013-09-30 2015-05-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 マーキング方法、レーザー転写フィルム、インク組成物、マークが施された転写対象可食物及びその製造方法
CN104922158B (zh) * 2015-06-05 2018-11-02 中国人民解放军第三军医大学第三附属医院 粪菌胶囊及其制备与应用
CN105103858A (zh) 2015-08-17 2015-12-02 太仓市雅丰农场专业合作社 一种小麦的种植方法
CN105193858A (zh) * 2015-09-25 2015-12-30 南昌大学 一种天然粪便菌群移植在肠道疾病治疗中的应用

Also Published As

Publication number Publication date
AU2016274757A1 (en) 2018-01-04
KR20180016539A (ko) 2018-02-14
KR102342925B1 (ko) 2021-12-23
KR102066242B1 (ko) 2020-01-14
BR112017026586A2 (pt) 2018-08-14
US20170252303A1 (en) 2017-09-07
WO2016201114A1 (en) 2016-12-15
CA2986915C (en) 2023-09-19
AU2025203820A1 (en) 2025-06-12
CN107921072A (zh) 2018-04-17
AU2016274757B2 (en) 2019-02-07
EP3939601A1 (en) 2022-01-19
JP6616431B2 (ja) 2019-12-04
IL281424B2 (en) 2023-10-01
US10391064B2 (en) 2019-08-27
AU2025203820A9 (en) 2026-03-19
AU2022256174A1 (en) 2022-11-24
AU2020220084A1 (en) 2020-09-03
BR112017026586B1 (pt) 2021-11-03
JP6907288B2 (ja) 2021-07-21
US10226431B2 (en) 2019-03-12
AU2019203164A1 (en) 2019-05-30
JP2020037573A (ja) 2020-03-12
AU2020220084B2 (en) 2022-07-21
HK1254281A1 (zh) 2019-07-19
IL256033B (en) 2021-03-25
IL256033A (en) 2018-01-31
KR20200127060A (ko) 2020-11-09
CA2986915A1 (en) 2016-12-15
ES2889902T3 (es) 2022-01-14
US20160361263A1 (en) 2016-12-15
JP2018516960A (ja) 2018-06-28
EP3307289B1 (en) 2021-08-04
AU2022256174B2 (en) 2025-02-27
IL281424B1 (en) 2023-06-01
EP3307289A1 (en) 2018-04-18
AU2019203164B2 (en) 2020-05-21
KR102175829B1 (ko) 2020-11-06
IL281424A (en) 2021-04-29
KR20200006181A (ko) 2020-01-17

Similar Documents

Publication Publication Date Title
IL281424A (en) Microbiota restoration treatment preparations and production methods
IL242934B (en) Microbiota restoration therapy (mrt) compounds and methods of manufacture
IL260257A (en) Preparations and methods for the treatment of hemoglobinopathies
ZA201707981B (en) Compositions of obeticholic acid and methods of use
IL254016A0 (en) A preparation for medical and preventive treatment produced by microbiota
EP3223838A4 (en) Gold kiwifruit compositions and methods of preparation and use therefor
IL248363A0 (en) Preparations containing a high dose of a tetracyclic compound, methods for their preparation and their uses
EP3207048A4 (en) Compositions and methods of treating muscular dystrophy
SG10202004071UA (en) Cryoprecipitate compositions and methods of preparation thereof
EP3131556A4 (en) Methods and compositions for treatment of copd diseases
EP3215132A4 (en) Methods of administering amantadine compositions
EP3253211A4 (en) Compositions and methods for treatment of edema
EP3154952A4 (en) Methods and compositions for treatment of her-positive cancers
SG11201803284YA (en) Novel method of use and compositions
ZA201802376B (en) Compositions and methods for treatment of homocystinuria
PL3113774T3 (pl) Kompozycje grapiprantu i sposoby ich zastosowania
EP3151862A4 (en) Therapeutic detoxification compositions and methods of making and using same
EP3256094A4 (en) Dental compositions and methods of use
EP3344593A4 (en) COMPOSITIONS AND METHODS OF WELL CEMENTING
AU2015903210A0 (en) Compositions and methods of treatment
HK1262230A1 (en) Compositions and methods for delivery of therapeutic agents
GB201614997D0 (en) Oligosaccharide compositions and methods of making and using them
AU2015905131A0 (en) Methods and Preparation and Uses of Xanthorrhoeaceae Compositions
HK1262957A1 (en) Compositions and methods for treatment of liver diseases
HK1260504A1 (en) Compositions and methods for treatment of cancer