PL3319609T3 - Kompozycje i sposoby stosowania kombinacji leków przeciwbakteryjnych - Google Patents

Kompozycje i sposoby stosowania kombinacji leków przeciwbakteryjnych

Info

Publication number
PL3319609T3
PL3319609T3 PL16822054.9T PL16822054T PL3319609T3 PL 3319609 T3 PL3319609 T3 PL 3319609T3 PL 16822054 T PL16822054 T PL 16822054T PL 3319609 T3 PL3319609 T3 PL 3319609T3
Authority
PL
Poland
Prior art keywords
compositions
methods
drug combinations
antibacterial drug
antibacterial
Prior art date
Application number
PL16822054.9T
Other languages
English (en)
Inventor
Gautam Dantas
Patrick GONZALES
Kevin Forsberg
Mitchell PESESKY
Mayland Chang
Shahriar Mobashery
Original Assignee
Washington University
University Of Notre Dame Du Lac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington University, University Of Notre Dame Du Lac filed Critical Washington University
Publication of PL3319609T3 publication Critical patent/PL3319609T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL16822054.9T 2015-07-09 2016-07-08 Kompozycje i sposoby stosowania kombinacji leków przeciwbakteryjnych PL3319609T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562190588P 2015-07-09 2015-07-09
PCT/US2016/041565 WO2017008034A1 (en) 2015-07-09 2016-07-08 Compositions and methods of use of antibacterial drug combinations

Publications (1)

Publication Number Publication Date
PL3319609T3 true PL3319609T3 (pl) 2022-12-05

Family

ID=57686086

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16822054.9T PL3319609T3 (pl) 2015-07-09 2016-07-08 Kompozycje i sposoby stosowania kombinacji leków przeciwbakteryjnych

Country Status (9)

Country Link
US (3) US10500191B2 (pl)
EP (2) EP3319609B1 (pl)
JP (3) JP6845511B2 (pl)
CN (2) CN108289896B (pl)
DK (1) DK3319609T3 (pl)
ES (1) ES2929058T3 (pl)
PL (1) PL3319609T3 (pl)
PT (1) PT3319609T (pl)
WO (1) WO2017008034A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3319609T3 (da) * 2015-07-09 2022-08-22 Univ Washington Sammensætninger og fremgangsmåder til anvendelse af antibakterielle lægemiddelkombinationer
CN107789355B (zh) * 2016-09-07 2022-04-12 湘北威尔曼制药股份有限公司 含有哌拉西林的复方药物组合物及其应用
US10434089B2 (en) 2017-01-25 2019-10-08 The Johns Hopkins University Avibactam and carbapenems antibacterial agents
US11376237B2 (en) 2017-10-03 2022-07-05 Melinta Subsidiary Corp. Methods of treating bacterial infections
US11690810B2 (en) * 2018-11-14 2023-07-04 The Chinese University Of Hong Kong Combination treatment of bacterial infection
CN110279692A (zh) * 2019-07-17 2019-09-27 中南大学湘雅二医院 一种抗感染组合物、制剂及其应用
GB202100378D0 (en) * 2021-01-12 2021-02-24 Quadram Inst Bioscience Methods and compositions for antibiotic potentiation
CN113559099A (zh) * 2021-08-27 2021-10-29 丹诺医药(苏州）有限公司 包含舒巴坦和阿维巴坦的药物组合物及其应用
CN117940127A (zh) * 2022-07-05 2024-04-26 塞戈瑞·弗拉基米罗维奇·西多连科 治疗多种耐药细菌感染的制剂
CN115778949A (zh) * 2022-12-15 2023-03-14 复旦大学附属华山医院 用于抑制产kpc酶肺炎克雷伯菌的组合物、药物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565456A (zh) * 2003-06-14 2005-01-19 张哲峰 一种头孢吡肟抗菌组合药物
CA2686348A1 (en) * 2007-05-21 2008-11-27 Hans Rudolf Pfaendler Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems
BRPI0916885B8 (pt) * 2008-08-28 2021-05-25 Astrazeneca Ab composição farmacêutica
CN102349897B (zh) * 2011-07-22 2012-12-26 深圳市新泰医药有限公司 一种美罗培南钠/他唑巴坦钠药物组合物
CN103648496B (zh) 2011-07-26 2016-05-25 沃克哈特有限公司 包含β-内酰胺抗生素、舒巴坦和β-内酰胺酶抑制剂的药物组合物
WO2013085152A1 (en) * 2011-12-07 2013-06-13 Union Korea Pharm Co., Ltd. Combined antibiotics comprising cephalosporins and beta-lactamase inhibitors
US20150258072A1 (en) 2012-09-03 2015-09-17 Wockhardt Limited Antibacterial compositions
GB201306980D0 (en) * 2013-04-17 2013-05-29 Blueberry Therapeutics Ltd Methods
CA2983992A1 (en) * 2015-04-30 2016-11-03 The Regents Of The University Of Colorado, A Body Corporate Polycyclic indoline and indolenine compounds
DK3319609T3 (da) 2015-07-09 2022-08-22 Univ Washington Sammensætninger og fremgangsmåder til anvendelse af antibakterielle lægemiddelkombinationer
WO2017203266A1 (en) * 2016-05-25 2017-11-30 Entasis Therapeutics Limited Combination therapy for treatment of resistant bacterial infections

Also Published As

Publication number Publication date
JP2021075560A (ja) 2021-05-20
EP3319609A1 (en) 2018-05-16
EP3319609B1 (en) 2022-06-15
CN108289896A (zh) 2018-07-17
DK3319609T3 (da) 2022-08-22
ES2929058T3 (es) 2022-11-24
JP2018525434A (ja) 2018-09-06
US20180200226A1 (en) 2018-07-19
US11559514B2 (en) 2023-01-24
US20200054605A1 (en) 2020-02-20
CN108289896B (zh) 2022-03-01
US20230293488A1 (en) 2023-09-21
WO2017008034A1 (en) 2017-01-12
CN114796499A (zh) 2022-07-29
HK1258393A1 (zh) 2019-11-08
PT3319609T (pt) 2022-08-23
JP7121954B2 (ja) 2022-08-19
US10500191B2 (en) 2019-12-10
JP6845511B2 (ja) 2021-03-17
EP3319609A4 (en) 2018-12-12
JP2022141948A (ja) 2022-09-29
EP4112057A1 (en) 2023-01-04

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