PL3325443T3 - Sposób otrzymywania pridopidyny - Google Patents
Sposób otrzymywania pridopidynyInfo
- Publication number
- PL3325443T3 PL3325443T3 PL16828644.1T PL16828644T PL3325443T3 PL 3325443 T3 PL3325443 T3 PL 3325443T3 PL 16828644 T PL16828644 T PL 16828644T PL 3325443 T3 PL3325443 T3 PL 3325443T3
- Authority
- PL
- Poland
- Prior art keywords
- pridopidin
- obtaining
- obtaining pridopidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/24—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195756P | 2015-07-22 | 2015-07-22 | |
| PCT/US2016/043682 WO2017015609A1 (en) | 2015-07-22 | 2016-07-22 | Process for preparing pridopidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3325443T3 true PL3325443T3 (pl) | 2022-08-01 |
Family
ID=57834816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16828644.1T PL3325443T3 (pl) | 2015-07-22 | 2016-07-22 | Sposób otrzymywania pridopidyny |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10047049B2 (pl) |
| EP (1) | EP3325443B1 (pl) |
| AR (2) | AR105434A1 (pl) |
| CA (1) | CA2993607C (pl) |
| DK (1) | DK3325443T3 (pl) |
| ES (1) | ES2922991T3 (pl) |
| HU (1) | HUE059158T2 (pl) |
| PL (1) | PL3325443T3 (pl) |
| TW (1) | TW201718491A (pl) |
| WO (1) | WO2017015609A1 (pl) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012028635A1 (en) | 2010-09-03 | 2012-03-08 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| MX347209B (es) | 2011-12-08 | 2017-04-19 | Teva Pharmaceuticals Int Gmbh | La sal de bromhidrato de pridopidina. |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| DK3010506T3 (da) | 2013-06-21 | 2021-07-12 | Prilenia Neurotherapeutics Ltd | Pridopidin i behandling af huntingtons sygdom |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| US9907786B2 (en) * | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US11471449B2 (en) | 2015-02-25 | 2022-10-18 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| US10603311B2 (en) | 2015-02-25 | 2020-03-31 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| JP7034488B2 (ja) | 2016-02-24 | 2022-03-14 | プリレニア・ニューロセラピューティクス・エルティーディー | プリドピジンを使用する神経変性眼疾患の治療 |
| DK3504187T3 (da) | 2016-08-24 | 2025-04-14 | Prilenia Neurotherapeutics Ltd | Anvendelse af pridopidin til behandling af funktionel tilbagegang |
| CN110012661A (zh) | 2016-08-24 | 2019-07-12 | 普瑞尼亚医疗发展有限公司 | 普利多匹定用于治疗肌张力障碍的用途 |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| BR112019015000A2 (pt) | 2017-01-20 | 2020-04-07 | Prilenia Neurotherapeutics Ltd. | uso de pridopidina para o tratamento da síndrome do x frágil |
| EP3357909A1 (en) * | 2017-02-02 | 2018-08-08 | Sandoz AG | Crystalline 4-[3-(methylsulfonyl)phenyl]-1-propyl-piperidine |
| AU2018317346B2 (en) | 2017-08-14 | 2021-08-26 | Prilenia Neurotherapeutics Ltd. | Method of treating amyotrophic lateral sclerosis with pridopidine |
| CN111278431A (zh) | 2017-08-30 | 2020-06-12 | 普瑞尼亚神经治疗有限公司 | 普利多匹定的高浓度剂型 |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| JP2020533296A (ja) | 2017-09-08 | 2020-11-19 | プリレニア ニューロセラピューティクス リミテッド | 薬物誘発性ジスキネジアを治療するためのプリドピジン |
| AU2020218158B2 (en) | 2019-02-04 | 2023-08-03 | Prilenia Neurotherapeutics Ltd. | Low dose pridopidine for Parkinson's Disease and other diseases associated with parkinsonism |
| AU2021219072B2 (en) | 2020-02-13 | 2024-10-03 | Prilenia Neurotherapeutics Ltd. | Combination therapy for treating amyotrophic lateral using pridopidine and another active agent |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
| EP4519246A4 (en) | 2022-05-03 | 2025-08-13 | Prilenia Neurotherapeutics Ltd | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE |
| IL315049A (en) | 2024-08-15 | 2026-03-01 | Prilenia Neurotherapeutics Ltd | Taste-masking compounds containing pridopidine, their use and method for their preparation |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE201669T1 (de) | 1991-04-17 | 2001-06-15 | Upjohn Co | Substituierte (s)-3-phenylpiperidin derivate, deren herstellung und deren verwendung als dopamin autorezeptor antagonisten |
| SE9702716D0 (sv) | 1997-07-15 | 1997-07-15 | Ross Nicholas Waters | Substituted phenylazacycloalkanes in the treatment of cognitive disorders |
| SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| PL1802573T3 (pl) * | 2004-10-13 | 2017-03-31 | Teva Pharmaceuticals International Gmbh | Proces syntezy 4-(3-metanosulfonylofenylo)-1-N-propylopiperydyny |
| AU2005293755A1 (en) | 2004-10-13 | 2006-04-20 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Process for the synthesis of 4-(3-sulfonylphenyl)-piperidines |
| CN101711236B (zh) | 2007-04-12 | 2012-10-31 | Nsab神经研究瑞典公司分公司 | 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物 |
| WO2011107583A1 (en) | 2010-03-04 | 2011-09-09 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders |
| WO2012028635A1 (en) | 2010-09-03 | 2012-03-08 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| CN103958469B (zh) * | 2011-09-07 | 2016-04-20 | 梯瓦制药国际有限责任公司 | 一种新的普利多匹定盐酸盐多晶型形态 |
| MX347209B (es) | 2011-12-08 | 2017-04-19 | Teva Pharmaceuticals Int Gmbh | La sal de bromhidrato de pridopidina. |
| AU2013243461A1 (en) | 2012-04-04 | 2014-11-06 | Teva Pharmaceuticals International Gmbh | Pharmaceutical compositions for combination therapy |
| US20140088145A1 (en) | 2012-09-27 | 2014-03-27 | Teva Pharmaceutical Industries, Ltd. | Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| WO2014052933A1 (en) | 2012-09-27 | 2014-04-03 | Teva Pharmaceutical Industries Ltd. | Laquinimod and pridopidine for treating neurodegenerative disorders |
| DK3010506T3 (da) | 2013-06-21 | 2021-07-12 | Prilenia Neurotherapeutics Ltd | Pridopidin i behandling af huntingtons sygdom |
| EA201691454A1 (ru) | 2014-01-22 | 2017-01-30 | Тева Фармасьютикалз Интернэшнл Гмбх | Композиции придопидина модифицированного высвобождения |
| TW201613859A (en) | 2014-06-30 | 2016-04-16 | Teva Pharma | Analogs of PRIDOPIDINE, their preparation and use |
| CA2970799A1 (en) | 2014-12-22 | 2016-06-30 | Teva Pharmaceuticals International Gmbh | L-tartrate salt of pridopidine |
| US10603311B2 (en) | 2015-02-25 | 2020-03-31 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to improve cognitive function and for treating Alzheimer's disease |
| WO2016138135A1 (en) | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
| US20170020854A1 (en) | 2015-07-22 | 2017-01-26 | Teva Pharmaceuticals International Gmbh | Pridopidine base formulations and their use |
-
2016
- 2016-07-21 AR ARP160102219A patent/AR105434A1/es active IP Right Grant
- 2016-07-22 PL PL16828644.1T patent/PL3325443T3/pl unknown
- 2016-07-22 DK DK16828644.1T patent/DK3325443T3/da active
- 2016-07-22 WO PCT/US2016/043682 patent/WO2017015609A1/en not_active Ceased
- 2016-07-22 ES ES16828644T patent/ES2922991T3/es active Active
- 2016-07-22 HU HUE16828644A patent/HUE059158T2/hu unknown
- 2016-07-22 TW TW105123329A patent/TW201718491A/zh unknown
- 2016-07-22 US US15/217,683 patent/US10047049B2/en active Active
- 2016-07-22 CA CA2993607A patent/CA2993607C/en active Active
- 2016-07-22 EP EP16828644.1A patent/EP3325443B1/en active Active
-
2024
- 2024-08-14 AR ARP240102151A patent/AR133546A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2993607A1 (en) | 2017-01-26 |
| DK3325443T3 (da) | 2022-07-18 |
| TW201718491A (zh) | 2017-06-01 |
| EP3325443A4 (en) | 2019-01-16 |
| AR133546A2 (es) | 2025-10-08 |
| WO2017015609A1 (en) | 2017-01-26 |
| EP3325443A1 (en) | 2018-05-30 |
| US20170022158A1 (en) | 2017-01-26 |
| US10047049B2 (en) | 2018-08-14 |
| CA2993607C (en) | 2024-01-16 |
| HUE059158T2 (hu) | 2022-10-28 |
| AR105434A1 (es) | 2017-10-04 |
| ES2922991T3 (es) | 2022-09-22 |
| EP3325443B1 (en) | 2022-06-08 |
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