PL336206A1 - Method of preventing mammary carcinoma by means of selective modulators of oestrogen receptors - Google Patents

Method of preventing mammary carcinoma by means of selective modulators of oestrogen receptors

Info

Publication number
PL336206A1
PL336206A1 PL98336206A PL33620698A PL336206A1 PL 336206 A1 PL336206 A1 PL 336206A1 PL 98336206 A PL98336206 A PL 98336206A PL 33620698 A PL33620698 A PL 33620698A PL 336206 A1 PL336206 A1 PL 336206A1
Authority
PL
Poland
Prior art keywords
mammary carcinoma
selective modulators
oestrogen receptors
preventing mammary
preventing
Prior art date
Application number
PL98336206A
Other languages
English (en)
Inventor
Andrew Lawrence Glasebrook
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL336206A1 publication Critical patent/PL336206A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PL98336206A 1997-04-09 1998-04-07 Method of preventing mammary carcinoma by means of selective modulators of oestrogen receptors PL336206A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4311897P 1997-04-09 1997-04-09
PCT/US1998/006989 WO1998045286A1 (en) 1997-04-09 1998-04-07 Prevention of breast cancer with selective estrogen receptor modulators

Publications (1)

Publication Number Publication Date
PL336206A1 true PL336206A1 (en) 2000-06-05

Family

ID=21925594

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98336206A PL336206A1 (en) 1997-04-09 1998-04-07 Method of preventing mammary carcinoma by means of selective modulators of oestrogen receptors

Country Status (15)

Country Link
EP (1) EP0975628A4 (no)
JP (1) JP2001518897A (no)
KR (1) KR20010006215A (no)
CN (1) CN1259945A (no)
AU (1) AU6957398A (no)
CA (1) CA2286207A1 (no)
EA (1) EA199900910A1 (no)
HU (1) HUP0001845A2 (no)
ID (1) ID23653A (no)
IL (1) IL132279A0 (no)
NO (1) NO994902L (no)
PL (1) PL336206A1 (no)
TR (1) TR199903244T2 (no)
WO (1) WO1998045286A1 (no)
ZA (1) ZA982818B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610706B1 (en) 1999-07-29 2003-08-26 Eli Lilly And Company Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride
US6653479B1 (en) 1999-07-29 2003-11-25 Eli Lilly And Company Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride
BRPI0818637A2 (pt) 2007-10-16 2015-04-07 Repros Therapeutics Inc Métodos de tratamento de sintoma da síndrome metabólica, de glicose em jejum prejudicada, da síndrome metabólica e de redução de níveis de glicose em, jejum em sujeito com hipogonadismo hipogonadotrófico secundário ou idiopático
JP2015508825A (ja) 2012-02-29 2015-03-23 レプロス セラピューティクス インコーポレイティド アンドロゲン欠乏症を治療するための併用療法
ES2671516T3 (es) 2013-02-19 2018-06-06 Novartis Ag Derivados de benzotiofeno y composiciones de los mismos como degradantes selectivos de los receptores de estrógeno
GB201311888D0 (en) * 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compounds
EP3373967B9 (en) 2015-11-10 2023-10-04 Paracrine Therapeutics AB Treatment of er-negative breast cancer with an pdgf-cc inhibitor and an anti estrogen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510357A (en) * 1995-02-28 1996-04-23 Eli Lilly And Company Benzothiophene compounds as anti-estrogenic agents
SG64896A1 (en) * 1995-02-28 1999-05-25 Lilly Co Eli Benzothiophene compounds intermediates compositions and methods
US5731342A (en) * 1996-02-22 1998-03-24 Eli Lilly And Company Benzothiophenes, formulations containing same, and methods

Also Published As

Publication number Publication date
NO994902D0 (no) 1999-10-08
CA2286207A1 (en) 1998-10-15
HUP0001845A2 (hu) 2001-06-28
EP0975628A4 (en) 2001-03-21
WO1998045286A1 (en) 1998-10-15
EP0975628A1 (en) 2000-02-02
EA199900910A1 (ru) 2000-04-24
KR20010006215A (ko) 2001-01-26
JP2001518897A (ja) 2001-10-16
ZA982818B (en) 1999-10-04
TR199903244T2 (xx) 2000-05-22
CN1259945A (zh) 2000-07-12
ID23653A (id) 2000-05-11
AU6957398A (en) 1998-10-30
NO994902L (no) 1999-12-07
IL132279A0 (en) 2001-03-19

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