PL3370698T3 - Kompozyty polimerowe zol-żel i ich zastosowania - Google Patents

Kompozyty polimerowe zol-żel i ich zastosowania

Info

Publication number
PL3370698T3
PL3370698T3 PL16805561T PL16805561T PL3370698T3 PL 3370698 T3 PL3370698 T3 PL 3370698T3 PL 16805561 T PL16805561 T PL 16805561T PL 16805561 T PL16805561 T PL 16805561T PL 3370698 T3 PL3370698 T3 PL 3370698T3
Authority
PL
Poland
Prior art keywords
sol
gel polymer
polymer composites
composites
gel
Prior art date
Application number
PL16805561T
Other languages
English (en)
Inventor
Sumitra RAJAGOPALAN
Wilms BAILLE
Piotr KUJAWA
Christopher A. Zook
Rebecca R. QUESNELL
Dennis L. Huczek
Stephen L. Secreast
Laibin Luo
Tammy A. Sanders
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of PL3370698T3 publication Critical patent/PL3370698T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
PL16805561T 2015-11-03 2016-11-02 Kompozyty polimerowe zol-żel i ich zastosowania PL3370698T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562250126P 2015-11-03 2015-11-03
US201662315756P 2016-03-31 2016-03-31
PCT/US2016/060015 WO2017079216A1 (en) 2015-11-03 2016-11-02 Sol-gel polymer composites and uses thereof
EP16805561.4A EP3370698B1 (en) 2015-11-03 2016-11-02 Sol-gel polymer composites and uses thereof

Publications (1)

Publication Number Publication Date
PL3370698T3 true PL3370698T3 (pl) 2022-04-25

Family

ID=57471981

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16805561T PL3370698T3 (pl) 2015-11-03 2016-11-02 Kompozyty polimerowe zol-żel i ich zastosowania

Country Status (16)

Country Link
US (2) US10064870B2 (pl)
EP (1) EP3370698B1 (pl)
JP (1) JP6864001B2 (pl)
KR (1) KR102145435B1 (pl)
CN (1) CN108601723B (pl)
AU (1) AU2016350868B2 (pl)
BR (1) BR112018009010B1 (pl)
CA (1) CA3002214C (pl)
CL (1) CL2018001194A1 (pl)
ES (1) ES2907686T3 (pl)
MX (1) MX374683B (pl)
PL (1) PL3370698T3 (pl)
PT (1) PT3370698T (pl)
RU (1) RU2761212C2 (pl)
UY (1) UY36973A (pl)
WO (1) WO2017079216A1 (pl)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201116559D0 (en) 2011-09-26 2011-11-09 Univ Leuven Kath Novel viral replication inhibitors
JOP20160086B1 (ar) 2015-05-08 2021-08-17 2 Katholieke Univ Leuven Ku Leuven Research And Development مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
JO3633B1 (ar) 2015-09-16 2020-08-27 Katholieke Univ Leuven Ku Leuven Research & Development مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
JOP20160198B1 (ar) 2015-09-16 2022-03-14 Janssen Pharmaceuticals Inc مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
AU2017233727A1 (en) * 2016-03-18 2018-09-13 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Chitosan hydrogels for accelerating involution and preventing infection of the mammary gland at drying-off
WO2017167953A1 (en) 2016-03-31 2017-10-05 Janssen Pharmaceuticals, Inc. Substituted indoline derivatives as dengue viral replication inhibitors
HRP20210847T1 (hr) 2016-03-31 2021-07-23 Janssen Pharmaceuticals, Inc. Supstituirani derivati indola kao inhibitori replikacije denga virusa
JOP20170069B1 (ar) 2016-04-01 2021-08-17 1 Janssen Pharmaceuticals Inc مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
EA201892200A1 (ru) 2016-04-01 2019-03-29 Янссен Фармасьютикалз, Инк. Замещенные производные соединений индола в качестве ингибиторов репликации вирусов денге
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
JOP20180025B1 (ar) 2017-03-31 2021-08-17 Janssen Pharmaceuticals Inc مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
JOP20180026A1 (ar) 2017-03-31 2019-01-30 Univ Leuven Kath مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
CN110536679B (zh) 2017-04-20 2023-03-31 硕腾服务有限责任公司 用于治疗乳腺炎的兽医用组合物和相关方法
CR20190531A (es) 2017-05-22 2020-03-05 Janssen Pharmaceuticals Inc Derivados de indolina sustituidos como inhibidores de la replicación vírica de dengue
CA3060583C (en) 2017-05-22 2024-06-04 Janssen Pharmaceuticals, Inc. Substituted indoline derivatives as dengue viral replication inhibitors
WO2018224680A1 (en) * 2017-06-09 2018-12-13 Bimeda Research & Development Limited Intramammary veterinary composition
CN109575484A (zh) * 2017-09-29 2019-04-05 天津城建大学 新型埃洛石/聚乙烯醇复合气凝胶及其制备方法和应用
EP3717034A1 (en) * 2017-12-01 2020-10-07 Zoetis Services LLC Hydrogel compositions and uses thereof
CN111801068A (zh) * 2018-01-18 2020-10-20 硕腾布鲁姆希尔Ip有限公司 内部乳头密封剂及其在预防干奶牛的牛乳腺炎中的应用
US20210299157A1 (en) * 2018-08-06 2021-09-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cellulose-based topical formulations
CA3120839A1 (en) * 2018-11-22 2020-05-28 Jichi Medical University Endoscope visual field-securing viscoelastic composition
AU2018452571B2 (en) * 2018-12-14 2025-06-19 Ecolab Usa Inc. Stable iodine-containing antimicrobial teat dip compositions
CN110437471B (zh) * 2019-07-11 2022-02-15 郑州轻工业学院 一种粘性复合水凝胶及其制备方法和用途
PH12022551160A1 (en) 2019-11-15 2023-09-25 Janssen Pharmaceuticals Inc Treatment and prevention of dengue disease
US20230021329A1 (en) * 2019-12-20 2023-01-26 Veri Nano Inc. Nanostructured binary gel composition and use thereof
CN111012947B (zh) * 2019-12-30 2021-11-12 南京财经大学 一种可注射和自愈合淀粉基水凝胶及其制备方法和应用
CN111214699A (zh) * 2020-01-08 2020-06-02 广州贝奥吉因生物科技股份有限公司 一种用于周围神经损伤修复的水凝胶及其制备方法
CN111840212B (zh) * 2020-06-18 2023-07-21 余祖功 一种非人类动物用乳头封闭剂及其制备方法
CN111825858B (zh) * 2020-07-02 2023-04-25 南京师范大学 一种基于两性离子和角蛋白的复合水凝胶及其制备方法
CA3194975A1 (en) * 2020-09-11 2022-03-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel or colloidal suspension derived from extracellular matrix, and uses thereof
WO2022217069A1 (en) * 2021-04-09 2022-10-13 Colorado School Of Mines Radical crosslinked zwitterionic gels and uses thereof
EP4329790A1 (en) * 2021-04-28 2024-03-06 Mileutis Ltd. Compositions and methods for modulating mammary disorders and conditions
CN113736435B (zh) * 2021-10-08 2023-05-12 扬州工业职业技术学院 一种钻井液用纳米微乳液封堵剂及其制备方法
CN114539574B (zh) * 2022-02-28 2023-06-06 浙江农林大学 压电-摩擦电耦合感应材料的制备方法和应用
CN117427203A (zh) * 2022-07-12 2024-01-23 北京石墨烯研究院 一种富含石墨烯的止血及抗菌用凝胶海绵
CN115990275A (zh) * 2022-10-08 2023-04-21 江苏省人民医院(南京医科大学第一附属医院) 一种黏膜下注射剂及其制备方法
CN115645635A (zh) * 2022-10-24 2023-01-31 杭州旸顺医疗科技有限公司 一种液相栓塞剂及其制备方法和用途
CN115804870B (zh) * 2022-12-02 2023-12-19 浙江大学 一种微创注射生物支架及其制造方法与应用
WO2024123809A1 (en) * 2022-12-06 2024-06-13 Tricol Biomedical, Inc. Flowable chitosan bioadhesive hemostatic compositions that resist dissolution
CN117362139A (zh) * 2023-10-27 2024-01-09 湖北航天化学技术研究所 一种提高电控固体推进剂力学性能的方法
WO2025160219A1 (en) * 2024-01-23 2025-07-31 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and compositions for treating reperfusion injury following myocardial infarction
WO2026117792A1 (en) * 2024-11-29 2026-06-04 The General Hospital Corporation Sustained release of purified collagenase clostridium histolyticum

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4333484A (en) 1978-08-02 1982-06-08 Philip Morris Incorporated Modified cellulosic smoking material and method for its preparation
US6074663A (en) 1995-01-16 2000-06-13 Baxter International Inc. Method of using cross-linked fibrin material
DK0971690T4 (en) 1996-12-18 2015-07-13 Bimeda Res & Dev Ltd Anti-infective intramammary veterinary composition.
CA2212300A1 (en) 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
DE60003459T2 (de) 1999-12-09 2004-05-06 Biosyntech Canada Inc., Laval Mineral-polymer hybrid-zusammensetzung
US20040047892A1 (en) 2000-11-15 2004-03-11 Desrosiers Eric Andre Filler composition for soft tissue augmentation and reconstructive surgery
NZ531618A (en) 2001-09-10 2005-03-24 Bimeda Res & Dev Ltd A bio-security system
KR100474945B1 (ko) 2002-01-10 2005-03-10 알앤엘생명과학주식회사 젖소의 원유 중 체세포 감소용 및 유방염의 예방 또는치료용 조성물
AU2004258746A1 (en) * 2003-07-31 2005-02-03 Pharmacia & Upjohn Company Llc Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
EP1718237A1 (en) 2004-02-02 2006-11-08 Bimeda Research And Development Limited A method and device for treating a teat canal of an animal
US20050191270A1 (en) * 2004-02-27 2005-09-01 Hydromer, Inc. Anti-infectious hydrogel compositions
EP2014708A1 (en) * 2005-01-13 2009-01-14 Cinvention Ag Shaped body made of a composite material
KR20070100836A (ko) * 2005-02-03 2007-10-11 신벤션 아게 졸/겔 기술에 의하여 제조된 약물 전달 물질
US9205046B2 (en) 2005-04-25 2015-12-08 The Governing Council Of The University Of Toronto Enhanced stability of inverse thermal gelling composite hydrogels
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
WO2007066837A1 (en) 2005-12-06 2007-06-14 Lg Household & Health Care Ltd. Delivery system for tooth whitening component using in situ gelling
ES2664229T3 (es) 2006-06-30 2018-04-18 Biomimetic Therapeutics, Llc Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador
NZ549249A (en) 2006-08-18 2009-10-30 Univ Massey Methods for reducing the incidence of mastitis by administration of keratin
EP2079477B1 (en) 2006-10-10 2017-07-26 Wisconsin Alumni Research Foundation Intra-mammary teat sealant formulation and method of using same to reduce or eliminate visual defects in aged cheeses
AU2007355106A1 (en) 2006-11-29 2008-12-18 Foamix Ltd. Foamable waterless compositions with modulating agents
US9034348B2 (en) 2006-12-11 2015-05-19 Chi2Gel Ltd. Injectable chitosan mixtures forming hydrogels
US8153612B2 (en) 2006-12-11 2012-04-10 Chi2Gel Ltd. Injectable chitosan mixtures forming hydrogels
JP5539727B2 (ja) * 2006-12-11 2014-07-02 チット2ジェル リミテッド ヒドロゲルを形成する新規な注入可能なキトサン混合物
WO2008134712A2 (en) 2007-04-30 2008-11-06 Living Proof, Inc. Use of matrix metalloproteinase inhibitors in skin care
CN101077377A (zh) * 2007-05-09 2007-11-28 史义林 防治牛、羊乳房炎的复方碘化壳聚糖涂膜剂及其制备方法
US20090081173A1 (en) 2007-08-10 2009-03-26 The Board Of Regents Of The University Of Texas System Methods and compositions involving bacteriophage isolates
GB2461186B (en) * 2008-04-21 2010-09-01 Otonomy Inc Controlled release corticosteroid compositions and methods for the treatment of otic disorders
US8318817B2 (en) * 2008-07-21 2012-11-27 Otonomy, Inc. Controlled release antimicrobial compositions and methods for the treatment of otic disorders
WO2010036945A2 (en) * 2008-09-26 2010-04-01 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
US20100143510A1 (en) * 2008-12-04 2010-06-10 Majid Razzak Intramammary teat sealant
US20100172889A1 (en) * 2008-12-05 2010-07-08 Catchmark Jeffrey M Degradable biomolecule compositions
DK2379635T3 (en) 2008-12-16 2016-12-05 Carlsberg As Cellulosic polymer material
US20100196347A1 (en) 2008-12-19 2010-08-05 Vladimir Kery Bone grafts with reduced protease activity and methods of selection and use
WO2011022070A2 (en) 2009-08-20 2011-02-24 The Regents Of The University Of California Perivascular stem cell composition for bone
CN101664381A (zh) * 2009-08-21 2010-03-10 天津生机集团股份有限公司 治疗奶牛乳房炎的原位凝胶缓释制剂的制备方法
CN102125516B (zh) * 2010-01-13 2014-03-26 北京大学 温敏型原位凝胶药物组合物
US9301976B2 (en) 2010-08-19 2016-04-05 The Regents Of The University Of California Compositions comprising perivascular stem cells and nell-1 protein
US20130287930A1 (en) 2010-12-16 2013-10-31 Specialites Pet Food Method for producing highly palatable dry cat food
GB201113606D0 (en) 2011-08-05 2011-09-21 Norbrook Lab Ltd Dual chamber syringe
WO2013062994A1 (en) 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating full thickness burn injuries
WO2013062995A1 (en) 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating deep partial and full thickness wounds and injuries
US9963627B2 (en) 2012-11-09 2018-05-08 Bioastra Technologies Inc. Nanostructured phase change materials for solid state thermal management
RU2521401C1 (ru) * 2012-12-07 2014-06-27 ГНУ Краснодарский научно-исследовательский ветеринарный институт Российская академия сельскохозяйственных наук (Краснодарский НИВИ) Средство для профилактики мастита у дойных коров в сухостойный период
KR102276326B1 (ko) 2013-03-13 2021-07-13 앙테이스 에스.아. 피부 회춘을 위한 펩타이드 및 이것을 사용하는 방법
EP2968113B8 (en) 2013-03-14 2020-10-28 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
SG11201507629XA (en) 2013-03-15 2015-10-29 Human Biomolecular Res Inst Compounds and matrices for use in bone growth and repair
EP2970586B1 (en) * 2013-03-15 2022-12-07 Genzyme Corporation Amine functional polyamides
TW201532621A (zh) 2013-04-22 2015-09-01 Neocutis Sa 抗氧化劑組成物及其使用方法
CN103381139A (zh) 2013-05-10 2013-11-06 南京农业大学 黄芪多糖注射用原位凝胶及其制备方法
BR112016005795B1 (pt) 2013-09-16 2022-07-12 Zoetis Services Llc Conjunto de infusão
CN104510729A (zh) 2013-09-26 2015-04-15 黄永 激活动物免疫抗性的脂肪酸及其衍生物的组合物
EP3200843A4 (en) 2014-10-03 2018-06-20 Cytori Therapeutics, Inc. Use of regenerative cells in mitigating burn progression and improving skin graft incorporation and healing

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US20170119785A1 (en) 2017-05-04
CN108601723A (zh) 2018-09-28
ES2907686T3 (es) 2022-04-26
KR20180075646A (ko) 2018-07-04
MX374683B (es) 2025-03-04
US20190030043A1 (en) 2019-01-31
UY36973A (es) 2017-06-30
CN108601723B (zh) 2022-05-17
JP2018536708A (ja) 2018-12-13
KR102145435B1 (ko) 2020-08-18
US10729698B2 (en) 2020-08-04
CA3002214C (en) 2022-01-04
RU2018115574A3 (pl) 2020-03-13
BR112018009010B1 (pt) 2023-09-26
PT3370698T (pt) 2022-03-02
RU2018115574A (ru) 2019-10-25
JP6864001B2 (ja) 2021-04-21
BR112018009010A2 (pt) 2018-10-30
US10064870B2 (en) 2018-09-04
RU2761212C2 (ru) 2021-12-06
AU2016350868B2 (en) 2022-03-31
WO2017079216A1 (en) 2017-05-11
CA3002214A1 (en) 2017-05-11
CL2018001194A1 (es) 2019-05-17
BR112018009010A8 (pt) 2019-02-26
AU2016350868A1 (en) 2018-05-10
MX2018005547A (es) 2018-11-09

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